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Xifaxan and Cramps: What Users Say

Cramps: mentioned by 4 users (4.2%)

Based on user experiences from 95 Xifaxan reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

bloating 15.8%
diarrhea 13.7%
gas 11.6%
constipation 9.5%
nausea 5.3%
cramps 4.2%
pain 4.2%
upset stomach 4.2%
brain fog 3.2%
depression 3.2%

Reviews for Xifaxan

Commonly mentioned side effects
  • Anonymous
  • March 2, 2012

For Irritable Bowel Syndrome with Diarrhea "It definitely helped with cramping and diarrhea, but I still did have the occasional episode of diarrhea. However, after 5 months, I'm back to where I started. I don't know how I feel about having to take an antibiotic every 5 months or if that's even recommended or safe."

8 / 10
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96 Report
  • bik...
  • June 2, 2015

For Irritable Bowel Syndrome with Diarrhea "Tested positive for SIBO. I had asked my GI doc for that test. Was happy to have an answer after years of suffering. I am also hypoglycemic, so the actual test for SIBO had my blood sugar super low... probably 2 days to recover from that! The first 2 days on the drug, I have felt dizzy and tired, and my arms super tingly (?). But the BMs improved immediately, so I didn't want to stop the Xifaxan. Now at 4 days, I'm not sure. Sometimes I start feeling amazing. I am also following a diet for candida and paying close attention to food combining. Just today, I started feeling the abdominal cramping come back! Really not sure what to do here...."

7 / 10
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47 Report
  • Anonymous
  • September 23, 2009

For Crohn's Disease "It took a few days for it to start working. I'm taking 2 pills a day. The first few days felt bad cramps, but after that, it felt like a complete cure. No bathroom trips, gained weight, I can eat anything without feeling bloated."

10 / 10
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55 Report
  • Yme...
  • Taken for less than 1 month
  • October 7, 2020

For Irritable Bowel Syndrome with Diarrhea "I started taking Xifaxan for suspected IBS and started having severe abdominal cramping within a few days. I called my doc six days in and told him I was in severe pain and had a low-grade fever, and he told me it’s normal to finish the 14-day course of treatment. I have suffered severe lower abdominal cramping. This is so bad I can’t stay silent when it happens, moaning and crying like a drama queen!"

1 / 10
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18 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.