Quetiapine for Insomnia User Reviews
Brand names: Seroquel, Seroquel XR
Reviews for Quetiapine
- Mar...
- Taken for 2 to 5 years
- July 9, 2021
"I would like to share the fact that this drug is prescribed for sleep at 25-50 mg maximum because the lower strength it acts like antihistamine, similar to sleep ease or other sleep meds that cause drowsiness. If used at stronger doses, it can engage not sleep favourable conditions, such as why it is used for depression and psychosis on label. I am a male weighing 210 lbs and take between 12.5 to a maximum of 25 mg. 25 knocks me out for 12-14 hours, 12.5 mg for more like 8 hours. I have studied this drug extensively and in most people (not all), it does not help sleep at higher doses. It can cause increased blood glucose at doses higher than 50 mg. Other negative effects are also shown in doses over 50 mg. I refer to a large study done recently in 2021."
- Bjo...
- Taken for 2 to 5 years
- March 4, 2021
"I've been taking 50mg Seroquel to sleep for a couple of years now. It works every night for me. Within half an hour of taking it, I am asleep for 6 hours. I tried quitting and got no sleep for days before giving up and taking it again. It felt like without it, I would never sleep again. Apparently, I'm dependent on it to sleep. Oh well, a good night's sleep is worth it. It's a 10 rating for me (minus 1 because I can't get off it)."
Frequently asked questions
- What are the strongest sleeping pills?
- Does Seroquel (quetiapine) help you sleep?
- What drugs cause tardive dyskinesia?
- The...
- Taken for 2 to 5 years
- January 15, 2021
"I read in various places that Seroquel is not a sleep med; apparently doctors and the like claim that that is not its purpose. Yeah, we know that, but I can assure you it is a very effective sleeping pill at 100mg. I have been taking it for four years and it has not failed me once. I've taken Trazodone and Ambien in the past, and I will say Seroquel is the best by far. I wake up completely refreshed, I have gained zero pounds, and it helps tremendously with helping one fall asleep and stay asleep. Give it a try, that would be my recommendation. Best of luck to you."
- Kps...
- February 21, 2020
"I have to start by stating every drug affects everyone differently, and some respond positively to certain meds, while others had horrible reviews. For me, this drug, quetiapine, literally saved my life. I was going on 3 weeks of no sleep from chronic stress. I was manic and could not sleep no matter what I tried. I took Xanax, over-the-counter antihistamines, downloaded meditation apps, etc. I was literally on the verge of the end of my life until my parents forced me to go to a behavioral health hospital. At intake, I was in the worst shape of my life, lost so much weight, and looked like a complete paranoid schizophrenic out of his mind. The psychiatrist told me that they were going to give me something to knock me out, and I asked what. She said Seroquel, and I asked what kind of drug is that, and she said an antipsychotic. I took 100 mg and sure enough, I finally got rest. It did take a while to get back to normal again, about a month, but I really believe if I hadn't been given this drug, it would have been the end of me."
Are you taking this medicine?
Your review helps others make informed decisions.- Lil...
- Taken for less than 1 month
- May 10, 2021
"Quetiapine 25mg has literally changed my life. I’ve been a poor sleeper all my life, but in the midst of menopause, I’m lucky to get 3 hours a night and developed anxiety, depression, and felt utterly lost. I have friends who are on large doses for bipolar features and tried 25 mg for sleep, and it worked. No daytime grogginess, just sleep. I could only use it for sleep, and happily my doc had no problem scripting off-label for me. It’s only been a few days, but I could cry with relief that I won’t spend 20 hours awake anymore. I’ve tried everything, and this medication at this dose has changed my life."
- You...
- Taken for 1 to 2 years
- February 10, 2021
"This medication was prescribed after I tapered off of Klonopin and could not sleep. I had weight gain at first but only because the doctor had me taking 200 mg. I tapered down to 25 mg and lost all the weight and still slept great. In fact, I felt much better on the lower dose and slept deeper. I had nightmares and sleep paralysis at the higher dose. It also helped my anxiety without feeling groggy the day after. I even take a half of the 25 mg to help soothe my anxiety. It’s been a game changer for me."
- Sle...
- January 2, 2021
"I was prescribed Quetiapine 25 mg for insomnia, however, I found out that it is not a sleeping pill because it’s for depression, schizophrenia, and anxiety. It has sedative side effects, so I guess that’s why it was prescribed to me for sleep. This pill causes me to sleep half the day and feel like a zombie the other half of the day. I don’t know how anyone can take this and work or take care of any responsibilities. I told my doctor that I can’t take this. Very disappointing that she prescribed this for me."
- Ins...
- Taken for 5 to 10 years
- January 29, 2021
"I went on Seroquel 6 years ago because I mentioned to my psychiatrist on a visit that I wasn’t sleeping well. She prescribed 150 ER, and it knocked me out at night. And reading the other reviews, I get what they are saying about the next day drowsiness. I'm now up to 300 mg ER, but I have to take it 3 hours before I go to sleep so it times out right. HOWEVER, even though it says it’s not addictive, I cannot sleep without it. I don’t want to be on sleeping medications forever. I’ve gone 5 days with no sleep when trying to quit. DO NOT TAKE! They are lying about its dependency!"
- Eda...
- Taken for 10 years or more
- February 25, 2020
"I have been taking quetiapine for more than 15 years for bipolar, but especially for insomnia. Lately, my brain feels sick and tired, and sometimes anxious all too often. I tried stopping taking the quetiapine, but it is absolutely impossible to sleep without it. I am taking 200mg, which is necessary. I understand that I can go insane without adequate sleep. My doctor up till now has not given me a solution. Do you have any suggestions I could try as I am caught between a rock and a hard place."
- Rac...
- Taken for less than 1 month
- August 25, 2020
"After quitting my 20-year marijuana habit, I developed insomnia, and then I developed anxiety about the insomnia. 50 mg of Seroquel works for my insomnia every single night. I am so thankful for it. It usually takes 30 minutes to kick in. Been on it for 3 weeks."
- SRa...
- Taken for 1 to 6 months
- December 2, 2020
"After trying MANY sleep remedies (Natural and prescription), I tried Seroquel as a last resort. This is the only thing that has worked for me!! I only take 12.5 mg and have no ill side effects. I am so very thankful my doctor suggested this. It helps turn off all the worry during the night so I can sleep 8-9 hours. A true miracle!"
- Mer...
- Taken for 2 to 5 years
- November 12, 2020
"I have been on Quetiapine for sleep for about 3 years. Started at a low dose but increased up to 200mg, which I have been on for about 2 years. I get sleepy about 20 minutes after my dose and can sleep a full 8 hours. It has been a complete game changer for me."
- All...
- Taken for 5 to 10 years
- February 2, 2021
"5 years on Trazodone and quetiapine for sleep. 50mg-75... A month ago, I decided to start the process, with my doctor's approval, to decrease my dosage. 37.5mg for 3 weeks, 4 weeks later 12mg, 4 weeks later I'm done. Last night was the first night. Woke up 1.5 hours earlier. And a little out of sorts. But I know this will pass. The traz, I'm on 1/2 tab, soon I'll be off of that. It can be done. Put tabs of melatonin in the pill holder or bottle instead. You have to get off this stuff. And you will."
- Jac...
- Taken for 2 to 5 years
- February 14, 2021
"I’ve been taking quetiapine for over 3 years, and it absolutely has helped me sleep. I began on a 25mg dosage but self-reduced the pills to a quarter dosage to wean myself off of them about 3 months into my prescription. What worries me is that if I forget to take my little 6.25mg portion of the pill, then I wake up after 2 hours of sleep each and every time. After trying for 3 or 4 days, I become so tired that I start using them again. These work well, just too well."
- Lea...
- Taken for 1 to 6 months
- August 16, 2020
"After years of chronic insomnia, my GP prescribed 25mg of Quetiapine. It's been a miracle drug for me. Still waking in the night, but able to go back to sleep and get a full 8 hours. Godsend is all I can say :) Only weird thing is that I have a lot more vivid dreams - weird!"
- Dad...
- Taken for 6 months to 1 year
- January 17, 2021
"Got prescribed this for sleep after trazodone failed to help. It is VERY powerful at the 25mg dose for me. Please let your psych know if you have frequent or strong side effects to medicine before using. It knocks me out and keeps me asleep, but makes me VERY groggy in the morning, like I am hungover, and makes me hungry while I'm getting drowsy. Be sure to go straight to bed after you take it to combat eating and risks of dizziness."
- Dev...
- January 24, 2021
"I've been on it for a week and a half for insomnia. Taking 75 mg per night and helps with sleep but can often wake and not get back to sleep after only an hour. Have felt increased anxiety the next day which is worse than when I don't sleep at all. I haven't been diagnosed with any particular mental illness but would consider myself to have some form of PTSD. My thoughts are not normal and have increasingly intrusive thoughts and ruminations. Will be getting off this from today and hopefully on something that levels me out and helps me sleep. Strange how we all react so differently"
- Cof...
- Taken for 5 to 10 years
- January 14, 2021
"Seroquel saved my life. Due to PTSD, I have had insomnia for over 7 years. It was so bad, I felt crazy and unstable. I contemplated suicide daily, and I couldn't function. I was finally able to sleep with Seroquel after trying everything else. Unfortunately, it made me gain a lot of weight, and I have very irregular periods. I don't want to continue long-term, but it does help me sleep at night. I could not function without it."
- Rip...
- Taken for less than 1 month
- June 13, 2014
"Now I realize my experience is somewhat limited, but if my doctor had not prescribed it for me about four days ago, I might be typing from a rubber room. Because of certain very stressful life events, I began to experience insomnia about two months ago. For those two months, I was getting approximately 3 hours of fragmented sleep a night. I started taking 50 mgs of this medicine four nights ago, and I'm getting 7-8 hours of sleep per night. This medicine broke the anxiety > insomnia > anxiety > insomnia cycle. Once you're in the circle of that cyclical hell, it's very difficult to break out of it."
- Toi...
- Taken for less than 1 month
- January 2, 2021
"I'm on a very small dose of Seroquel. The side effects are really horrible. I need to use my glasses all day because I keep making spelling errors, and it does not affect my pain medication (morphine sulfate)."
- bob...
- Taken for 5 to 10 years
- February 15, 2020
"Seroquel at 25 mg is a miracle sleep inducer. I took it for 10 years every night. One night I was away and without the pill. Guess what, horrible sleep! Lately I'm taking 50 mg as 25 mg seems to give now 6.5 vs 8 hours of sleep. Just like Tramadol fixed my depression, Seroquel fixed my sleep. These two meds don't send your psychiatrist to conferences in Maui and Tahiti, hence the lack of interest."
- gas...
- Taken for 2 to 5 years
- February 13, 2014
"I have been taking quetiapine for 3 years to help me sleep. For me, it is wonderful. I take 50-100 mg before bed every night, unless I am on call as I am a physician. If I go to bed within 30 minutes of taking it, I usually sleep well. One cup of coffee in the morning and I am good to go. Prior to quetiapine, sleep was nearly impossible, and sleeping pills would make me more useless the next day than if I just stayed up all night. I'm glad to have access to quetiapine."
- tiz...
- Taken for 1 to 6 months
- May 3, 2020
"Up until my gastric sleeve surgery in 2012, sleep was never an issue for me. If anything, I slept too much. Fast forward to 2020 and for the last 8 years I have suffered horrible to mild insomnia and even on a good night, I may get 5 hours of sleep. I have tried all the common sleeping scripts out there along with some pretty serious anti-anxiety drugs, which ended with pretty bad results (a week in the hospital). In February of this year, I went in for my normal physical, except my normal doctor had left the practice and the new doc filling in for her was the one I got to see. I explained all that I wrote above, and she reviewed my chart. She asked if anyone had ever suggested Quetiapine, which they hadn't. I'm currently on day 61 of taking 50mg a night with 7-9 hours a night being the new norm. I'm so thankful this wonderful doctor came into my life. I'm not sure if any other doctor would have even considered this drug. So far no adverse side effects or weight gain. :)"
- Ahm...
- Taken for less than 1 month
- August 19, 2024
"OMG! This medicine is life-changing. Just read reviews and tried it instantly. Bang! It knocked me out in an hour. Had the best sleep of my life. Trust me, guys. I have tried almost all drugs for my weak sleep cycle. But nothing worked so well. Please do give it a try. I had a 25 mg dose at 9 PM, and by 10 PM, I was blackout. I had almost 8-9 hours of deep sleep, which I never had before. I didn’t have deep sleep in ages. Thank you so much, everyone, for your reviews. Just because of your reviews, I had the best sleep of my life."
Are you taking this medicine?
Your review helps others make informed decisions.Learn more about Insomnia
- Anticholinergic Drugs to Avoid in the Elderly
- Benzodiazepines: Overview and Use
- What are the dangers of mixing sleeping pills with alcohol?
Care guides
Symptoms and treatments
Medicine.com guides (external)
More about quetiapine
- Check interactions
- Compare alternatives
- Pricing & coupons
- Reviews (2,251)
- Drug images
- Side effects
- Dosage information
- Patient tips
- During pregnancy
- Support group
- Drug class: atypical antipsychotics
- Breastfeeding
- En español
"I have been prescribed 25mg quetiapine for sleep and am baffled as to how the people who are prescribed 100mg a day could remain conscious? After being on this for 2 years, I am still totally knocked out by one 25mg tablet. Most nights, I take half a tab or less. I haven’t noticed any increased tolerance in the time I have been on it. Anyway, can someone tell me, is my reaction abnormal? If not, how do any of you on doses of 50, 100, up to 800 stay awake? Once I take 25mg, that’s it, I am gonna sleep, like it or not. I have read that it is prescribed in doses up to 800mg for bipolar and thought omg if someone with bipolar was prescribed it at the doses I read (around 250mg) and they reacted like me, they would literally be incapable of functioning at all. So I was just curious, if you have bipolar, does bipolar, by its nature, mean you have a much higher tolerance or different reaction? Or is my reaction to 25mg abnormal?"