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Pyridostigmine and Headaches: What Users Say

Brand names: Mestinon, Regonol, Mestinon Timespan

Headaches: mentioned by 4 users (6.8%)

Based on user experiences from 59 Pyridostigmine reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

cramps 18.6%
diarrhea 15.3%
shortness of breath 10.2%
headaches 6.8%
muscle aches 6.8%
upset stomach 6.8%
blurred vision 5.1%
fatigue 5.1%

Reviews for Pyridostigmine

Showing 4 reviews tagged with "headaches". Clear filters to view all 59 reviews.
Commonly mentioned side effects
  • svh...
  • Taken for 1 to 2 years
  • October 29, 2022

For Dysautonomia "It took me quite a while to tolerate Mestinon, mostly nausea and headache and twitchiness, but after being on it for about two years, I have almost no side effects. It wears off after several hours, and I take it 3 times a day. It is difficult for me to take it at night, but it would probably help even more if I could. I also take magnesium, which stopped my ectopic heartbeats and muscle rigidity, cramps, and spasms. I was pretty lucky to be prescribed this so soon after having COVID."

10 / 10
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25 Report
  • D1a...
  • September 1, 2018

For Dysautonomia "I have been on this a week and it seems to be significantly helping breathing issues at night, overall dryness everywhere, constipation, nausea, and urinary retention. Side effects, though, are very unpleasant-very blurry vision (especially at night or in darker lighting), headaches, pelvic pain, muscle cramps, and overall fatigue. I am currently taking a dose of 40 mg three times a day."

7 / 10
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40 Report
  • Anonymous
  • Taken for 1 to 6 months
  • September 14, 2022

For Dysautonomia "I had been on Mestinon for 6 months. In the meantime, I felt bad from the beginning. My brain fog worsened, and at times, it was hard to move my tongue, almost stroke-like symptoms. In the beginning, it caused severe nausea and headaches. I just saw my neurologist again, and he took me off of this drug. It definitely did not work for me."

1 / 10
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14 Report

Frequently asked questions

  • POT...
  • Taken for less than 1 month
  • February 17, 2017

For Dysautonomia "I started on 30 mg 2x daily. I had initial loose stools, but have gone back to constipation. I didn't get much relief from my tachycardia, and also noticed an increase in body twitches (not tremors). I'm now trying 60 mg 2x daily and I still have the increase in twitches and, most notably, headaches (worse than the normal everyday ones), and breathing issues (I already have asthma and laryngospasms). Not sure any benefit is worth these side effects, but it's only been a couple of days, so I'll give it a little more time."

3 / 10
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34 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.