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Promethazine for Sedation User Reviews (Page 4)

Brand names: Promethegan, Phenadoz, Antinaus 50, Anergan 50 Adgan

Promethazine has an average rating of 5.9 out of 10 from a total of 118 reviews for the treatment of Sedation. 47% of reviewers reported a positive experience, while 33% reported a negative experience.

Reviews for Promethazine

  • Big...
  • Taken for less than 1 month
  • May 19, 2017

"Did nothing at all. Took another one, nothing. Very disappointed. After reading these reviews I really thought I'd found something that would help me sleep. Only one person it didn't work for. Guess I'm number two. Typical."

1 / 10
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11 Report
  • Bean
  • August 29, 2018

"For trouble falling asleep (no problem with staying asleep). I work as a heavy machinery operator. Prescribed by my dr. I asked for a short acting sleep aid. 1st attempt- Took at 8pm. Didn't sleep any earlier. Felt strange and disconnected next day until afternoon. 2nd attempt a week later- Taken 10am for nap. Didn't work. But my sinus cough cleared right up- wonderful! Still awake and alert at 6pm I went to dinner. I didn't get my usual red neck flush from beer- then at 8pm I became very drunk and uncontrollably sleepy after 4 beers. I was asleep by 9pm. Results: It stops sinus drip and cough in 30 mins. It prevents face flushing reaction to food and alcohol. It gets a bit sedating after around 10 hours and wears off around 18 hours later. Be very careful with alcohol even many hours later!!! Conclusion: Not useful for getting to sleep. Too long acting. To sleep at 9pm I would need to take it at work in the morning, too risky."

5 / 10
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9 Report
  • Lynn
  • Taken for 1 to 2 years
  • October 28, 2020

"I been taking this medicine for 2 years for my IBS which is very very bad and I get it around 3 am I wake up with stomach spasm so bad feels like having a baby with no medicine for pain, I passed out plenty of times because of how bad the pain gets so my Gastro doctor give me promethazine and the good part is I don’t have to take it every day sometimes I only take it once or twice within a year but it works good just it’s hard for me to wake up if I take it at 3am I don’t wake up till 8pm the next day I love how it works but I hate can’t wake up"

10 / 10
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6 Report

Frequently asked questions

  • McNab
  • Taken for less than 1 month
  • October 9, 2018

"I am in a quandry. For the past 10 months I have taken zopliclone nightly. My psychiatrist wants to wean me off it but any night I haven't taken it I haven't slept. Lack of sleep is detrimental to the stability of my mental health. I have been given choices A. for my quetiapine to be increased to aid my sleep (prob increasing my weight further) or B. to have my zopliclone replaced with promethazine but quite frankly having read the reviews here of people who already have experience with promethazine the reviews don't fill me with confidence that promethazine will be as effective as zopliclone. In an ideal world I'd stay on zopliclone but it isn't my choice and my psychiatrist says I will become tolerant to zopliclone."

1 / 10
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8 Report
  • Phehe...
  • Taken for less than 1 month
  • June 11, 2023

Phenergan (promethazine) "Taken to help me sleep, didn't really feel it worked as still awake at 1 am (took it at 8 pm). The next morning I couldn’t wake up. I was tired all the next day, dry mouth, and was exhausted. Had to stay home as could barely open my eyes. Won’t be taking it again."

2 / 10
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2 Report

Are you taking this medicine?

  • Night...
  • Taken for less than 1 month
  • October 11, 2021

Phenergan (promethazine) "I have recently started taking phenergan, I take two 50mg tablets about 20 minutes before sleep. 9 times out of 10 I'm having the most intense nightmares! I've literally just woke up from another. These tablets do work however you need to be mindful nightmares can occur."

5 / 10
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3 Report
  • Anonymous
  • Taken for less than 1 month
  • May 10, 2018

"This helped me on and off. I used to take sominex which is also promethazine hydrocloride but yeah it doesn't work every time so I suggest you take it now and again with not any more then 2 tablets (50mg). It does help with appetite and can give you that high feeling I remember being on it once and sleeping for like 20 hours"

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  • Anonymous
  • Taken for less than 1 month
  • July 15, 2021

"Be careful. For sedation yes works, I was given this to help the transition from one snri to ssri and I was initially told to take 2 at night I went for only one. Yes it worked but the next day I had a hangover like I been drinking all night, and only had a hours sleep.. sounds fun was not a nice relaxing feeling, more you are fighting to feel yourself again... so use with caution, if I have to use again a quarter of one would do the job Regards"

5 / 10
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3 Report
  • Jay
  • Taken for 1 to 6 months
  • June 29, 2022

"Have been taking this drug for a month, for insomnia. The first couple of nights I was excited to experience getting off to sleep which was a relief! After about a week despite sleeping I was feeling very tired during the day with a very low mood. After a couple of weeks, its effectiveness in helping me sleep had reduced and I was feeling more nervous during the day. Now after a month, I wake up if I do sleep with intense feelings of nervousness for hours which never really goes, and experience dreams at night that causes anxiety. I intended to reduce the dose and come off these pills."

3 / 10
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2 Report
  • C J
  • Taken for less than 1 month
  • September 17, 2023

"Interesting results with this drug. The first time I took 25mg, it completely wiped me out in about an hour after taking and led to an 11-hour sleep, something I've never had before. I would be lucky to sleep for 4 hours, so it worked as expected. But... The next day, I felt really weird, slightly light-headed. People commented on how 'spaced out I looked', so I clearly wasn't in a position to drive or work. Although this was a weekend, thankfully, so only take this if absolutely needed and expect side effects the next day."

7 / 10
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  • Not...
  • Taken for less than 1 month
  • June 6, 2022

Phenergan (promethazine) "I only take Phenergen for sleep as a last resort, and only the low dose. Phenergen does help me sleep, but it gives me intense nightmares and leaves me feeling really stressed and anxious. It also makes me drowsy the next day, so I basically can't function. Even for sleep though, it only works for a few days and then wears off. So only good for the short-term in my case. I wouldn't dare try the stronger stuff, I think it would be too much. As for allergies, it works well and instantly. So there's that at least. Still get the side-effects though."

6 / 10
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  • Nicky
  • Taken for less than 1 month
  • March 27, 2022

"This drug has ruined my life. I have been researching it since..I’ve been on a Phyche ward as a direct result. I woke up extremely trippy & started trying to kill myself, my son had to go with my parents, he is heartbroken. I was fitting in the hospital as well.I am now paranoid. I never sleep & my life as I know it is over. My whole personality has gone. I’m paranoid & after almost 2 months can still feel it in my face brain & body. My tongue swelled up & was hanging out I couldn't breath. I hallucinated & lost my cognitive abilities & my personality. I know my son can’t come home as this has not got better. I cannot organise myself. I have autism & adhd-generalised anxiety. I felt dizzy everything wobbled & I now don’t know what to do with myself. All I could say when I woke up was "it just won’t go” - and it still hasn’t"

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  • Boo
  • Taken for less than 1 month
  • August 6, 2021

"My doctor said I should try these instead of the usual zopiclone I have been prescribed for severe bouts of insomnia. I took two 25 mg tablets and they took over two hours to start making me sleepy . I still woke up a few times but went back to sleep and when it was time to get up for work, I was so groggy weak and disorientated I had to call in sick . The grogginess and malaise lasted into the evening. I don't think I'll be taking them again, the grogginess is way too much. Zopiclone knock me out straight and didn't make me as groggy next day even though they make me get a headache and feel irritable, I prefer that to the severe groggy feeling."

4 / 10
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  • Finnian
  • Taken for less than 1 month
  • May 1, 2023

"Literally only been taking it for three days and my insomnia is actually worse than it was beforehand. I was told it would only take 30 minutes to kick in but I tossed and turned for up to 3 hours, then woke up every hour or so for absolutely no reason. I'm honestly not sure if I want to continue taking it because I'm even more exhausted than I was previously, with a wicked headache and dry mouth to boot. Its only saving grace is that it might help deal with some of the nausea that comes with starting a new antidepressant, but even then I'm doubtful it will."

1 / 10
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  • sleep...
  • Taken for less than 1 month
  • January 21, 2023

"Has anyone else found it doesn't work? I had episodes of acute anxiety and wasn't sleeping. I was prescribed promethazine to help with sleep. I was told to take it on alternate nights. The first night I slept until 5 am but since then I sleep from 11 pm until 1 or 2 am and that's it. I often wake with a racing heart and drenched in sweat."

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  • Anonymous
  • Taken for less than 1 month
  • August 31, 2022

"I was having problems finishing work at 09:15 in the morning and returning to work the same day at 9:15pm and only sleeping for 3 hours between but now I take one and I wake 7-8 hours later and can stay alert at night easily. I take one tablet a week."

10 / 10
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1 Report
  • Deano
  • Taken for 2 to 5 years
  • September 18, 2021

"This medication did make me drowsy, but it gave me horrendous restless legs, which kept me awake all night, unless I took codeine with it, I later realised I was basically taking it every night, promethazine and codeine can stop you breathing in your sleep. I've stopped taking it, but I'm always craving it because the mix of the 2 is so addictive, it's like liquid heroin, a few rappers have died from overdosing on it."

1 / 10
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  • Bridge
  • Taken for less than 1 month
  • September 3, 2021

"I was on a big dose of temazepam sleeping pills per night. Still didn't sleep. 4 valium, still didn't sleep. Largactil, serequal, clonozepam, pot, cbd oil, therapy. They either did nothing or I built up a tolerance within a very short period of time. Phenergan 50mg was suggested by psyche. I have severe CPTSD, bi polar, depression, shocking anxiety. With phenergan and a valium, I sleep. Maybe 5 -6hrs. I have to have breaks and use oxycontin as I suffer chronic pain, fibromyalgia, emphysema. It helps sleep then I build a tolerance, so round n round we go. Yes I walk daily. Meditate. See a psychologist. See a psychiatrist. Have a great supportive partner and my doggy. My mind is wired differently. Good luck to you all. I would highly recommend Phenergan. Start at 25mg first though."

9 / 10
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  • dataB...
  • Taken for 2 to 5 years
  • October 7, 2022

"I take 50mg two hours before bed was the ONLY medication that would give me 7 hours of sleep. Usual sleep was 4 to 5 hours with the usual sleep meds (if they worked). Unfortunately at this high dosage the drug can cause seizures. This was the only side effect but I had to stop. If you can tolerate 50mg, it worked amazing for chronic insomnia."

8 / 10
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  • 3purp...
  • Taken for 1 to 2 years
  • January 16, 2022

"I have used this medication for three different purposes, in syrup form combined with Dextromethorphan and the one with codeine for cough, I was given this once IM injection at urgent care and sent home with a 5 day supply of 25mg twice a day to be taken as needed for nausea and vomiting, the first time I took this in tablet form it was 25mg, and I slept for 12 hours, uninterrupted sleep for 12 hours, I woke up on my friend's couch very confused and disoriented. My psychiatrist has given it to me a few times when my insomnia is really bad, and sedation is just absolutely necessary. It is not used for insomnia in the United States, but it is used for insomnia in Europe. I can't drive a car the next day if I take this at night, it makes me extremely sleepy, and I really don't think it is a safe drug for me to take at home. If I was in the hospital, I would not care if it was given to me because who wants to be in the hospital, right? mostly used for nausea/vomiting and cough syrup combo"

8 / 10
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  • MayGo...
  • Taken for less than 1 month
  • September 28, 2023

Phenergan (promethazine) "I may have had an auditory hallucination using this. Took 3mg just to be cautious. Small tablets. Ambo had mentioned it to me, so I gave it a go. OTC in Australia. The pharmacist told me to use no more than three times a week. Not bad."

7 / 10
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  • suzq
  • Taken for 1 to 2 years
  • January 11, 2024

"I've taken this to help with sleep and anxiety. I can take 50mg at night. At first, it worked quite well, but now not so much and I will soon be stopping it to find something else that will help balance my mood and have a sedating effect. I think short-term it is good, but you do become reliant on it to sleep, and after a while, it doesn't work as well. If I don't have it, I would be awake all night! I still struggle to sleep, taking 50mg now."

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  • Mike
  • Taken for 1 to 6 months
  • February 18, 2022

"Take this as I struggle to sleep due to stress and horrendous anxiety. My Dr wouldn't give me sleeping tablets so recommended phenergan. I take two 25mg before bed and it takes about 1 hour until I'm super chilled and sedated. Honestly best thing you can get over the counter. Only slight issue is for some reason I get an hungry and tend to raid my kitchen but I'd still rather have this medication with me"

9 / 10
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  • Rik
  • Taken for less than 1 month
  • February 1, 2022

"Taking 25mg promethazine for insomnia due to anxiety/panic/ocd since a week or 2 now for insomnia. It helps me well, it helps me fall asleep without any significant side effects (I nod off a bit more easily during the day but that's OK). Only downside is that I'm not allowed to drive with it in my country."

9 / 10
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  • Sharon
  • Taken for 6 months to 1 year
  • October 5, 2021

"Recently I had some trouble sleeping (had an accident due to not enough sleep/too much work) and so went to the doctor to see if I could get stillnox (which I'd had previously) and he suggested promethazine. It works great if I take it about 3 hours before I want to sleep (either 25mg - sometimes works) or 50mg (always works unless I'm extremely stressed). However I do notice I'm 50% slower and dumber at all work tasks the following day if I take 50mg. Sometimes it's worth it though just for a good night's sleep. Normally I just take it occassionally, but one week I was having a lot of trouble sleeping and so I took at bigger dose. When I woke up the next morning my phone was in the bathroom sink and I have no memory of how it got there. So overall it worked well but I'm sticking to 50mg max from now on. Also, I don't think this would have worked for me 15 years ago when I had real insomnia but it works now for fairly mild sleep problems."

8 / 10
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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

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