Promethazine for Sedation User Reviews (Page 3)

• Megan
• Taken for less than 1 month
• October 12, 2020

"Horrible: Did its job for sedation but knocked me out for 16 hours after I had already had a full nights sleep. I ended up going to the hospital because it was such an adverse effect my neighbours couldn't wake me up properly when they came to check on me, I couldn't hear them calling me. The hospital added it to my allergy list. A few days after I started having extremely strong panic attacks, I had never had them before and put it down to Phenergan. I've read other reviews mentioning increased anxiety after taking it. It doesn't work for everybody."

• Kez
• Taken for 1 to 6 months
• June 19, 2018

"Having suffered torn cruciate ligament this couple of months, I've found phenergan to be a good sedative. I'm a bit worried about long term use, if anyone can help. I've been taking 25mg for the last 8 weeks to aide sleep. Any information would be greatly appreciated."

• Yatesie
• Taken for 5 to 10 years
• February 8, 2019

"Being an insomniac on and off (maybe once or twice a week as needed) for as long as I can remember, I find the only thing that really helps is Promethazine. It doesn't make me feel nauseous the next day like a lot of other sleeping tablets, both OTC and script. It can take a few hours to work, so I need to take it at least a couple of hours before I want to go to sleep. There is one negative - nightmares. I haven't heard from many other people who have experienced the same thing, but let me tell you, they can be horrendous - the worst kind of terror you can imagine. The weird thing is, sometimes I get them, sometimes I don't! And the half life is 12-16hrs or something, so you can be quite fatigued the next day. Overall though, in spite of all it, it's a winner for me."

• MMK
• December 2, 2019

"I’ve been familiar with promethazine since I was a baby (now 27). Nowadays I work 1-3 x 12 hour overnight shifts per week and suffer terrible allergies. Before going on dymista for my hayfever I would take 10-25 mg of phenergan each night (or day depending if I’m working) with a 2mg SR melatonin and tbh, after a week of continuous use the phenergan no longer sedates me (down-regulated receptors I think?). However if I take a break from it, one 10mg will knock me out in an hour. I sleep deeply and feel groggy the next day. It also helps my anxiety and the nausea I sometimes get with melatonin. However there are side effects; headaches, fatigue, and because it relaxes the muscles in sleep, mild sleep apnoea. I sometimes wake from dreams, gagging/dry retching or gasping for air. I also suffer from VCD and find I’m more susceptible to attacks when regularly taking phenergan. I read somewhere than neuroleptic drugs can do this. So now I take it if needed."

• xxxnsh
• Taken for 1 to 6 months
• October 17, 2021

Phenergan (promethazine) "I have really bad insomnia. I can not get to sleep at all. I take 50 mg of phenergan. And it takes a while to work like 4 hours then I fall asleep. I have tried other meds and they work for a short time but it is slow to work so that I lay in bed for at least 4 hours till I fall asleep, but hey least it works."

• Ghand
• August 28, 2015

Phenergan (promethazine) "I was prescribed this for my 6 yr old daughter to help her sleep. I've only been using it a couple of nights but it doesn't seem to be working. I am giving her the 3x5ml dose and giving her it at 6pm and up to now she is still not going to sleep before 11pm. Am I not giving her enough or not giving it enough time to work? Advice greatly appreciated! Thanks"

• HDano
• Taken for less than 1 month
• August 1, 2020

"My physician of three years thought it wise to change from Ambien 10 mg to Phenergan 25 mg for no apparent reason other than he feared Ambien dependency. Well yes I have primary insomnia per a sleep study, prescribed Ambien 10 mg and it has worked well for 19 years. Never needed to increase the dose. The Phenergan/ promethazine 12.5 mg took the face off my head. Yes I slept but 20 hours later am still looking for my face, that is, I am hungover with mild cognitive impairment so as not to be able to drive. For some the side effects aren't worth the sleep. I am one of those. It's back to the Ambien 10 mg or a new doctor."

• Jano
• Taken for less than 1 month
• October 10, 2020

"Have taken promethazine for 3 nights, have been struggling to sleep for a couple months now. Has done nothing but give me a slight headache around my temples. If anything I feel like this has kept me awake."

• KPano
• Taken for less than 1 month
• May 22, 2020

"Tried promethazine these to help with restless legs syndrome at night and think it made it worse. Not sure whether it was me waiting for them to work that made me more agitated or the tablet. Stopped taking them after 3 nights of hardly any sleep."

• skinn...
• Taken for less than 1 month
• August 9, 2018

"This is the worst drug I've ever taken. Headaches, tongue swelling, eye lids swelling and a rash on them. I've got sore legs, sore arms and feel so ill. My doctor took me off Zoplicone and replaced it with this medicine I WOULDNT RECOMEND THIS DRUG TO ANYBODY OR GIVE TO A PATIENT WITH MENTAL HEALTH PROBLEMS"

• JohnC
• Taken for 1 to 6 months
• February 22, 2018

"This drug works for insomnia but it seems to have a very long half life and I feel groggy the next day, plus it also gives me depression which can linger for at least a couple of days after taking it, depression is a common side effect of antihistamines especially the strongest anticholinergic ones like Promethazine/Phenergan."

• Sleep...
• September 20, 2017

"I was given 25mg to take night time. I found myself waiting hours before it kicks in. Everyone said the next day how well I looked however my brain was a bit fuzzy the following day. I shall use this drug to create a sleep routine and then only use it sparingly for emergencies of sleeplessness. I found myself sleeping through the night for the first time in years."

• seasi...
• Taken for 1 to 2 years
• February 4, 2017

"Before you take this for sleep, particularly if you are giving it to children, please read information about withdrawal. I was taking it for Prozac induced insomnia. Coming off Prozac was easy. Coming off phenergan is awful. It has been likened to coming off opiates. I am on day two. I am hoping by Monday it will be out of system and I can restart my life drug free."

• Mike
• Taken for 1 to 6 months
• March 27, 2022

Phenergan (promethazine) "Take 50mg at night to help me sleep as it takes away the anxiety. It works a treat. I'm very sedated and calm after 1 hour and can sleep 8 hours. Only down side I seem to crave sugar foods like chocolate so I tend to binge (can eat whole entire packet of biscuits in 10 mins)"

• Joano
• July 9, 2019

"I have taken 25 mg Promethazine on and off for a few months. It is not over the counter where I live, either. Some nights it works really good. But, some nights I toss and turn. I think the 25 mg is not working anymore. May have to up the dose? Did not know it could induce seizures."

• jay
• Taken for less than 1 month
• April 2, 2021

"My Gp had prescribed me promethazine to help combat my chronic insomnia. These pills have done absolutely nothing. I took two x 20mg pills 1 hour before bed and it literally did nothing. I had another sleepless night where I woke up about 4-5 times. I carried on taking them for the next 4 days to see if anything changed but no hope. I’m sorry but these are useless."

• Francis
• Taken for 1 to 2 years
• May 23, 2018

"I first used promethazine as 'when required med' when I was inpatient on a psych ward, and found that although it worked and helped calm me down and I stop hurting myself, it made me extremely drowsy. At the same time I was on melatonin but found that even 12mg (more than the highest recommend dose for a child my age) didn't help. I asked my doctor to switch my sleep Meds to a mix of both but he refused as we wouldn't know which one helped. At first he put me on 25mg (of promethazine) but after 2 months I had to have it upped to 50mg as I had grown too tolerant. I am not on melatonin and it works a treat with no side effects. ♡"

• Stuffl
• Taken for less than 1 month
• April 20, 2017

"I was given this stuff when in labor as I had felt nauseated I think they put it right into my IV. I vomited anyway, but suddenly didn't care much about it. It relaxed me so much that I fell asleep off and on between labor. Since I also have PTSD along with severe insomnia, I wouldn't mind trying it for sleep. It can't be worse than Ambien, where I usually don't know that I ransacked the kitchen and pillaged everything that I could stuff into my mouth. When I wake up in the morning I find the kitchen in mysterious disorder but have no memory eating anything, or even getting up. At least with Phenergen I wouldn't have to worry about it."

• Cathy
• Taken for 6 months to 1 year
• February 13, 2020

"Been prescribed promethazine to help sleep for approx 6 months now. Initially it was my psychiatrist who prescribed it due to the reluctancy to prescribe diazepam incase of dependency and addiction. I was put on the maximum dose of 100mg daily for agitation and to help me sleep (I don't usually have sleep problems but when I do they are awful since it's trauma related night terrors). I took them nearly every day and still couldn't tell you for sure if they helped. I think they may help reduce my agitation slightly but for sleep I'm uncertain. That tells me they aren't that effective if I can't even figure out if they made a difference. It's frustrating because I'd hoped this would be a good alternative to diazepam."

• Samy
• February 16, 2022

"I have used promethazine on and off for years to continue sleeping when I get broken sleep. But noticed recently that as well as feeling drugged all day it leaves me with low mood and irritability too. Just wanted to warn others of being careful specially if you suffer from depression or going through difficult time."

• Hudrion
• March 8, 2017

"I can't say this drug has NO effect, but I'm a chronic insomniac and have been treated for it with Xanax or Klonopin for at least the last 20 years. While mild doses of those drugs have induced sleep, when I've desired more sleep than those "benzos" have allowed me, I've tried Promethazine in varied doses, from 12.5 to 75 MGs and it just doesn't induce sleep like I had hoped. It's very effective for reduction of nausea, but I'm lucky if it barely makes me drowsy. Sometimes, even the higher doses had no effect at all. BOTTOM LINE: This med gets great reviews, so it works for some, but I'm proof that it's not effective for EVERYONE."

• Corol...
• March 16, 2018

"I took 50mgs of the promethazine for sleep, it took at least 2 hours to start working. Once it kicked in I was beyond tired, I fell asleep in my bed for about an hour and woke up, I got up to head outside for a cigarette I got dizzy and laid on my living room floor and was out for another good hour. After getting back to bed fell asleep for like 5 hours and woke up drenched in sweat having to change clothes, sheets etc. Overall worked good to go to sleep besides the sweating side effects and feeling fuzzy after its worn off. Most likely would not take again due to the sweats."

• Miche...
• Taken for 1 to 6 months
• September 3, 2018

"Have severe anxiety and was given this to take in the morning and before bed. It worked well the first 2 night's sent me straight to sleep but now It takes hours to fall asleep and I wake during the night many times think this is due to my anxiety being severe and needing a stronger dose. No side effects which is great."

• Dude
• Taken for 1 to 6 months
• April 26, 2018

"I suffered a head injury and had a really hard time being able to sleep afterwards. After trying Amitryptiline, doxepin nortriptyline without success, Promethazine/phenergan was the answer. It wore off a little after a while and then including 1x Ashwagandha 300mg (herbal supplement) it regains a good effect and have been able to reduce the dose from 25mg to 10mg. Takes about 1 hour to take effect. Is especially good to keep you asleep during night."

• Devle...
• October 3, 2017

"I've seen people on here say , this is NOT an over the counter medication where I live. Also this is nothing like ambien - ambien is a benzodiazepine medication, so if you're expecting that then don't! Works good for upset stomach as well as mild sedation, don't expect a "xanax" effect, but they will help with your appetite, and allow for some rest, also works good to help nausea if you take medications that make you sick, like morphine for example. I am NOT a professional or even in the medical field, there are way too many "shadetree" pharmacists out there so consult a real one for a real diagnosis or answer, its just they won't tell you what you "want" to hear like people on these forums will."