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Prochlorperazine for Nausea/Vomiting User Reviews (Page 5)

Brand names: Compro

Prochlorperazine has an average rating of 3.3 out of 10 from a total of 307 reviews for the treatment of Nausea/Vomiting. 22% of reviewers reported a positive experience, while 70% reported a negative experience.

Reviews for Prochlorperazine

  • peach...
  • Taken for 1 to 6 months
  • November 15, 2021

"I get severe nausea from IBS and anxiety, the only thing that has helped is prochloperazine 5mg! Don't be scared by these reviews, 95% of the bad reviews are talking about IV/injection prochloperazine, which clearly reacts very differently to the much lower pill dose. Within 30 minutes all of my nausea and most of my anxiety disappears, and it doesn't make me sleepy or dizzy either - unless I take more than one pill or take it with other medications that cause drowsiness. I never review medications but I had to show that not everyone has a bad experience with this med."

10 / 10
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  • This...
  • Taken for less than 1 month
  • November 17, 2019

Compazine (prochlorperazine) "I went to the ER for stomach issues as a teen and I took it went home and 45 minutes later my jaw shift all the way to the left and I couldn’t control it and my neck started leaning to the right I was rushed to the hospital and given Benadryl through an I’ve lucky it worked I was in so much pain"

1 / 10
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  • Katha...
  • June 23, 2020

Compazine (prochlorperazine) "took this for a migraine cycle and while it helped with the migraine. When the nurse gave it to me it made my heart race and it made me have the worst panic attack, I couldn’t stay still because my legs were restless and I was extremely hot and loopy I won’t take this again."

2 / 10
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  • Ahri
  • Taken for less than 1 month
  • October 31, 2016

Compazine (prochlorperazine) "I had been suffering from severe nausea and vomiting on and off including migraine, fever and flank pain. It was my second time in the ER so they gave me compazine and I'd never had it, it relieved my nausea and migraine but I started feeling so restless I was freaking out, like I wanted to rip out my iv and leave and run away. Then they told me it's a side effect and I already suffered from severe anxiety it made it 1000x worse. I had the worst time trying to sleep, then had the weirdest dreams of my life. They gave me Morphine shortly after which calmed me a little and took the rest of my pain away but I was hoping it'd honestly put me out. 24hrs layer and I still feel that restlessness in my body but it's so much better than it was."

1 / 10
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  • Drambo
  • Taken for less than 1 month
  • November 5, 2022

Compazine (prochlorperazine) "Was given this drug in the ER for a migraine and nausea, they didn’t tell me what they were given and I had the worst headache and didn’t even ask. Low and behold this medicine ruined my life after one dose!!! Was given with bendrayl and I felt extremely anxious panicky my legs and body were so restless I thought I was gonna die on the CT table I couldn’t put words together. It’s been 5 days and I’m still not the same panic attacks galore anxiety tight band around head/headache fear of doom and dizziness galore. This should be illegal"

1 / 10
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  • Super...
  • August 22, 2019

Compazine (prochlorperazine) "I feel for all of you very much. All of those bad experiences, I also had. Plus doctors and nurses don't seem to care at least most don't. About 13 years ago I went to the ER for nausea, vomiting and diarrhea. I didn't feel well when I went in. As soon as they Compazine in my IV, I felt terrible panic, restlessness, anxiety. I could not sit, lay down stay in one place for more than 5 minutes. I pulled my IV out and started running to my friend. I thought maybe I had a stoke. I didn't know. My friend tried to talk to the doctors. I was out side I couldn't do anything to feel any better. I waited to die. I was afraid I would hurt someone. I was 1 of the top weightlifters in the world. I started bang my head as hard as I could on the concrete wall. Then I went back in the hospital bleeding. I thought then the doctors would do something to help me. They called the police, my friend got me home. I was worse. I took some Xanax. I still have anxiety from that experience."

1 / 10
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  • Kswear
  • Taken for less than 1 month
  • July 21, 2019

Compazine (prochlorperazine) "I was given this awful medication in a migraine cocktail. Within minutes I was so anxious that I yanked my IV out and ran out of the hospital room. For hours I couldn't stop moving my legs. Its been 3 days and I'm still so anxious. I made the pharmacy write in notes that I was allergic to compazine - prochlorperazine so this never happens again."

1 / 10
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  • Hope
  • January 31, 2020

Compazine (prochlorperazine) "Was given this at the E.R about 4 months ago for gallbladder related nausea, had the worst panic attack I have ever experienced, tried to rip the I.V out of my arm and run out of the hospital, have had many extreme panic attacks since. I have had panic attacks before but never within 6 months of each other. I get them at least 10 times a month now. Wish I had never taken this medication."

1 / 10
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  • momlo...
  • Taken for less than 1 month
  • October 31, 2022

Compazine (prochlorperazine) "It has been a little over six months since I was given compazine through my IV, when I had a migraine and I am still not right. It’s important to note that prior to the injection I have never had any problems with mental health besides intermittent anxiety (mild). I went to the ER for a severe migraine that had been lasting a few days. I was given compazine through my IV for the pain. I immediately had the worst panic attack of my life. I can’t even compare it to other panic attacks I’ve had because it was profoundly horrific. Wanting to escape, suicidal thoughts, terror, wanting to rip the IV out of my arm, and extreme restlessness. I have had debilitating anxiety ever since. After readings many of the reviews, I see most people feel better after a few days, but that hasn’t been the case for me. Have now been struggling with never feeling at peace or comfort. I can no longer feel love, happiness, joy or even experience laughter. I walked out of that hospital a different person. Please avoid."

1 / 10
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  • Jesus...
  • Taken for 1 to 2 years
  • May 15, 2019

"I usually, but infrequently, take a dose of 2 'Buccastem' tablets, (placed high in between my upper lip and gum) containing 1.85mg of prochlorperazine each, in order to treat nausea (as well as migraine, if accompanying nausea). This invariably completely removes my nausea and migraine symptoms, enabling to get on with my plans for the day without any negative side effects. However, it reliably gives rise in me the pleasant side effects of calmness. I'm surprised to read its catastrophic reports on this forum. "

10 / 10
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  • FF89
  • Taken for 1 to 6 months
  • April 12, 2024

Compazine (prochlorperazine) "This medication has been very helpful for me with extreme nausea and vomiting. It was recommended that I take Benadryl with it for side effects, so I take one with one. It relieves my symptoms within 30 minutes; it's been a lifesaver. I didn’t have any adverse reactions like others, except fatigue, but that's to be expected, especially with the Benadryl."

8 / 10
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  • whaaaat
  • September 14, 2016

"THIS DRUG IS HELL!!!! I went to the ER because I was extremely dehydrated and feeling nausea and had a migraine. I had the CRAZIEST ANXIETY of my LIFE that lasted for 24hrs, and the worst part is that I'm prone to having anxiety panics from this moment. It took me a few years to be able to talk about about without having body memory of how horrible it was. PLEASE DON'T TAKE THIS."

1 / 10
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  • MissA...
  • Taken for 6 months to 1 year
  • February 18, 2019

Compazine (prochlorperazine) "I was given compazine for nausea and vomiting when I was having monthly (girls) problems which almost always included throwing up with pain. Violent spasms like tetney lockjaw I did thousands of dollars of damage to my teeth, and my whole jaw was crooked for days after. But Drs all told me it was "stress" all in my head not the meds. One time when I was in the hospital and they gave me compazine by injection it started within a few minutes, yup it was the compazine. Also have to be careful with other meds that may contain it. I had Tigan which worked pretty good but now no longer made. Last time Dr gave me Zofran but had a tough time getting the insurance to approve it as they wanted to give me the cheaper compazine generics. Be very very careful as I have had a few pharmacists tell me some other meds were not related only to find out that they were. Be sure to do your homework and double triple check what is in what."

1 / 10
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  • Liv
  • Taken for less than 1 month
  • March 21, 2019

Compazine (prochlorperazine) "I went to the ER when I was experiencing headaches and vomiting due to a new medication I was put on. The doctors gave me compazine, toradol and Benadryl through my IV. After a few minutes I experienced the worst feelings of my life. I was thrown into a huge panic attack, I couldn't sit still, my heart rate rose to over 130. I had to stay in the hospital for 5 extra hours just to get my heart rate to return to normal. It took 24+ hours for the initial panic feeling to go away and now going on 48 hours my head still feels all foggy and I get dizzy when I stand up for long periods of time. I hope I return to normal soon and I would not recommend this medication to anyone!!"

1 / 10
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  • Rys...
  • Taken for less than 1 month
  • March 4, 2019

"My daughter was prescribed this (@ 15) by her neurologist for 24/7 migraines as part of the "cocktail". Within 45 minutes of taking the med, she went from laying down in her room to running into my room and attacking me & breaking furniture. She paused and said "Mom, I am scared". Told the neuro, and SHE said that it was my daughter "just being a teenager". (Seriously??) She had her take it again- same reaction. I had to call 911 after her waking up at 3 am, raging/psychotic for 6 hours STRAIGHT. Police, fire department, ambulance came. I was afraid they would have to put her on a psychiatric hold, but she came out of it. The combo of a horrible doctor, and a HORRIBLE medication...NO THANK YOU! That poor child! I changed her doctor. That medication is so bad... SO BAD. All around HORRIBLE experience."

1 / 10
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  • Dee
  • Taken for less than 1 month
  • March 22, 2019

Compazine (prochlorperazine) "26 years ago I was prescribed this for vomiting and soon after I took it at home I had a stroke (at 22 years old) You can imagine the trauma I went through. I was home alone with my infant when it happened. I lost all control of the right side of my body. I could barely speak. I got to a phone in the house (no cellphone back then 26 years ago) and called my sister who lived closest to me. She couldn’t make out what I was saying until I started crying, then she realized I was in danger So she rushed over and got me to the nearby hospital. By the that time I was also beginning to swallow my tongue. I thought I was gonna die. I apparently passed out and when I came to I was hooked up to things, I was feeling much better from whatever they did for me, and had told me I had a stroke. Because of how young I was there wasn’t too much permanent damage. My right side of my face is still slightly lower or droopy than the other side from the incident but my brain is ok. Scary!"

1 / 10
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  • Jenn
  • Taken for less than 1 month
  • February 23, 2019

"Went to ER for vomiting. They gave me this drug. It made feel suicidal and more anxious that I ever have. I ended up having to leave AMA because they weren’t listening to me. I hope it wears off completely, quickly. I’m terrified it won’t. Please don’t let them give you this medication. It is awful!!!"

1 / 10
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  • Bee
  • Taken for less than 1 month
  • September 19, 2019

Compazine (prochlorperazine) "If you are ever offered a sedative / nausea medication please be aware that every single one of these recollections and experiences are true. I could compare almost exactly to each and every one of these stories. DO NOT TAKE COMPAZINE. It has been three days and I still do not feel normal."

1 / 10
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  • Anonymous
  • July 28, 2009

Compazine (prochlorperazine) "I am an older adult in good health. I originally had dizziness (possibly from a virus or sinus bug) which caused nausea. This medication took away both symptoms within 1-2 hours and I was able to carry on with my normal activities."

10 / 10
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  • Elano
  • Taken for less than 1 month
  • April 2, 2021

Compazine (prochlorperazine) "I’m honestly shocked this drug is still allowed to be administered. I have several chronic illnesses including mitochondrial disease, Ehlers Danlos syndrome, dysautonomia, gastroparesis, Migraines and more. Four years ago at 14 I was taken to the emergency room with a severe headache along with nausea and stroke like symptoms. I was given the migraine cocktail that included Compazine. I immediately felt a rush of adrenaline accompanied by the worst restless leg/body/burning sensation I’ve ever felt. I remember wanting to literally crawl out of my skin. I felt as though I was going crazy. I have been septic and close to death many times but genuinely cannot think of a more uncomfortable experience than being on this medication. It took 50 mg of IV Benadryl +3 mg of IV Ativan to get me to finally calm down"

1 / 10
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  • Vegas
  • Taken for 1 to 6 months
  • October 16, 2023

Compazine (prochlorperazine) "I have Lupus, and I used to get Promethazine with one of my meds that's really hard on my stomach. A few months ago, I had an appendicitis attack and was throwing up for weeks. The doctor gave me IV Compazine, which worked like magic and even calmed my anxiety from being sick and in the hospital. It worked so well for me; my doctor changed the Promethazine to Compazine as a daily med to help combat the side effects from my other meds. I've never had any of the side effects from Compazine that everyone else is describing. In fact, in addition to fixing my nausea issues, I'm a much calmer person, and I feel like it gives me energy. I guess I'm just a weird patient."

10 / 10
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  • Jennna
  • May 9, 2016

Compazine (prochlorperazine) "I was given this through an IV in the ER. I had terrible nausea and Zofran didn't touch it. Even though compazine did take my nausea away, it left me incredibly groggy yet restless. I spent the entire rest of the day in a haze. I've never abused drugs but I would imagine this is how you would feel when coming off of some sort of high yet it lasts all day long. I kept feeling angry and anxious as well. I would much rather have nausea and will never take this medicine again!"

3 / 10
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  • Migra...
  • Taken for less than 1 month
  • July 30, 2019

Compazine (prochlorperazine) "This drug made me feel worse than any drug I ever received. I had a migraine and at the A&E. It was pure mortal terror from the minute they went into my vein. I had them stop the infusion immediately but it was too late. My heart rate shot up, and I felt like I was going to die right there on the bed. Sleep came on and off, but not because of being relaxed. More like passing out repeatedly. I slept for 24 hours and still feel pretty horrible the next day."

1 / 10
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  • bulldog
  • Taken for less than 1 month
  • June 18, 2019

Compazine (prochlorperazine) "I suffer from severe headaches on occasion and usually Excedrin will do the trick. I had a headache several months ago that was there for 3 days. I finally broke down and went to the ER. They gave me Compazine and put me in a waiting room. Within five minutes I felt terrified like I had to get away. I told my wife to tell them to get my IV off me or I would rip it out of my arm. They let me sign-out AMA and I fled the hospital. For several hours after I felt like the walls were closing in and doom was imminent. I hate this medication and will NEVER take it again. Beware!!!"

1 / 10
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  • Bear
  • August 9, 2019

Compazine (prochlorperazine) "My doc gave me this medication over 20 years ago for nausea. I ended up having an allergic reaction. I had anxiety and I couldn’t relax all day. I went to hospital because of dystonia. Awful day. It also induced OCD which I have been dealing with ever since. Has this terrible medication triggered OCD in others?"

1 / 10
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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

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