Prochlorperazine for Nausea/Vomiting User Reviews (Page 3)

• NE603
• Taken for less than 1 month
• February 1, 2019

Compazine (prochlorperazine) "I had experience high agitation and restlessness with this drug before so it’s been in my allergy list, unfortunately I was going through a difficult procedure and it’s the only anti-emetic this office offered. It had been over 10 years since I took it so I figured I’d try it again. Bad idea. This drug causes severe anxiety, agitation, muscle pain and a general feeling of needing to rip out of your skin!! I remember now why it was on my DO NOT USE list, the affects stay with you for a long time too. I will never take this again.. there’s a reason it’s listed as a mental health drug/antipsychotic.. IMO it MAKES you psychotic."

• saaaa...
• February 21, 2016

Compazine (prochlorperazine) "Went to the ER twice with a severe migraine, both times given Compazine. It definitely helps with relieving the pain but the side effects out weigh it for me. Felt like my skin was crawling, restlessness, skin rash, dry mouth, anxiety (triggered a panic attack both times), brought up a lot of bad thoughts of how I was dying. Long term, rebound headache, insomnia, loss of appetite. Also had it with Benadryl once and that scared me."

• Birdie
• Taken for less than 1 month
• August 23, 2020

Compazine (prochlorperazine) "Went to the ER with extreme dizziness. They wound up giving me Compazine. I wasn’t even familiar with what it was. I felt strange at first, but then my hands contorted & froze. My mouth had almost completely clamped shut. An orderly or a CNA just happened to come by to empty trash. I barely was able to say please go get someone something’s not right. The dr at first thought I had stroked. He ran some test gave me some Benadryl which helped. I would never take this drug again."

• anony...
• November 29, 2018

Compazine (prochlorperazine) "My mother had a colonoscopy and had a vocal chord spasm which caused her to cough during it. They gave her some medicine (don't remember the name) to help dry up her secretions and calm down the coughing. This made her chest tight, painful, and made her feel nauseous after she got home. I took her to the ER, she is allergic to Reglan, so they gave her a mix of benadryl and compazine for nausea. Within 5 minutes she was jittering around and felt like she wanted to rip her IVs out and run home. Her anxiety skyrocketed and her heart rate went up to 154 bpms. It wasn't until they gave her Ativan that her heart rate went down and she was able to calm down. We got sent home & she was still anxious and fidgeting around for about 4 hours until she finally fell asleep. She woke up and still felt a little anxious & fidgety but not near as bad as last night. One of the worst experiences she & I have ever had and she is going to have it put as she is allergic so she never has to be through it again."

• Nana...
• August 2, 2016

Compazine (prochlorperazine) "I was taking zofran for years for severe nausea. During a hospital stay I was given Reglan and had horrible hallucinations and my skin was crawling like some people in the reviews had with Prochlorperazine. However Zofran stopped working for me during the last bout of nausea so my doc gave me Prochlorperazine which helped tremendously and thankfully I had no side effects."

• Babyj...
• Taken for less than 1 month
• October 22, 2018

Compazine (prochlorperazine) "I'm just getting this medicine for a headache cocktail. And let me tell you I wanted to jump out of my own skin I have never felt anything like it it was absolutely horrible do not let them give you this medicine especially if you have anxiety which I have and they knew that because I told them absolutely horrible like your legs have bugs all in them and they're just crawling everywhere never ever again!!!!"

• Usles...
• April 6, 2019

Compazine (prochlorperazine) "I was given a migraine cocktail that had compazine included in it. THIS MEDICATION MADE MY SYMTOMS A MILLION TIMES WORSE! I started with my heart pounding and a severe anxious feeling immediately. I was given this med thru an IV. It literally felt like an instant panic attack. It's been 4 days now and I still am having spontaneous bouts of anxiety due to this medication. The half life is 24 hours with this med and it's been well over 96 hours since I was administered it and I'm still experiencing side effects. I also got low blood pressure which gave me cold sweats, disorientation and I was freezing. My only relief was from hot baths which made my blood pressure go up some. I also had dissociation, as if I wasn't even myself, from this medication. I can not stress enough how awful this medication is and it should NOT be used as nausea relief unless it's for EXTREME circumstances. This medication is used in people with schizophrenia! I am still not myself days after and its miserable."

• Kayle...
• Taken for less than 1 month
• February 20, 2020

"I have anxiety but I was prescribed this medication for my vertigo and sickness problem I randomly have ATM and I’m so dizzy but after taking these I feel better. I then read that it can help with anxiety and my panic attacks have been so bad I just wanted them to stop. So I started taking the medication for anxiety and I haven't had an attack in 2 days really, but I’m reading all these reviews and now I’m scared to take it because of my panic attacks got worse I have no idea what I would do TBH. Not sure if I should carry on taking them if they give you permanent damage anxiety wise."

• Sonya...
• November 18, 2008

Compro (prochlorperazine) "I used it after a surgery when the anti-nausea patch wasn't working well enough. I took off the patch, used the suppository and had no more nausea. Used it again after several hours of vomiting and diarrhea due to assumed food poinsoning. It was BAD (vomiting every 20 minutes). Then I remembered I had a left over suppository. Used it and didn't throw up once afterwards. I was able to go to sleep and woke up hours later when my fever had passed. "

• NoGut...
• February 7, 2020

Compazine (prochlorperazine) "I was given Demerol & Compazine to combat migraine & experienced severe agitation. The dr recognized phenothiazine-induced akathisia & countered it with Benadryl & Ativan. Years later I was, again, treated for HA. I double-checked the dr knew I couldn't take Compazine. He ordered chlorpromazine & Valium. Unfamiliar with the generic, I didn't realize it was Thorazine (in the same class as Compazine). Another bad reaction. I pulled the IV out, fled & paced at home for 15 hours. Surely, the dr knew I'd react negatively. A couple years later back to ER for the 1st time since the Thorazine. I explained my reactions in detail. This time I was given Reglan. Again, I ripped out the IV & was headed for the door when the nurse caught me. Repeated doses of an antidote worked. I learned, subsequently, it's common to react badly to Reglan if you reacted to Compazine. Either the dr was poorly informed or simply willing to risk my well-being. I've suffered at home in silence with ever since."

• Damom
• January 2, 2019

Compazine (prochlorperazine) "Went to the ER for a severe migraine...they gave me compazine and benadryl. 20 min later I was in a severe panic...ripping my IV's out. Calling out to the nurse saying I was leaving!! They had to give me more benadryl to reverse it. I left the hospital feeling worse than I did when I went in!! Horrible experience!"

• Renae...
• October 30, 2015

Compazine (prochlorperazine) "Had nausea from chemo and radiation and was given Zofran. Zofran did nothing to curb the nausea. I was just recently changed over to Compazine and the nausea is gone! I've not experienced any side effects whatsoever."

• Silve...
• Taken for less than 1 month
• December 15, 2017

Compazine (prochlorperazine) "I was born with chronic pancreatitis and chronic migraines so vomiting is a for sure thing every time I visit the ER. I have never in my life been traumatized by a medication until this encounter. It is like we are their lab rats, you feel helpless, insane, delusional, 51-50, a psychopath. You literally feel trapped inside your body if that makes any sense. I try to hold my composure off this medication because it literally makes you crazy. It should be illegal for them to give inject you with it without a warning on the side effects. You feel so weird for 3 days, it’s as if your innocence has been robbed from you, a form of violation."

• Shay
• November 6, 2019

Compazine (prochlorperazine) "This was, like many others on here have said, a terrifying ER experience. I was given Compazine for what they thought was a migraine, plus benadryl because they warned me about the anxiety. Upon giving it to me via IV, I felt a wave of panic enter my body. My heart stopped for a moment. I immediately wanted to get out of the hospital and tried to rip my IV out. I thought that would be the end of it. But it wasn't. I had crippling anxiety over the next 5 days! Yes, FIVE days. I had constant panic attacks where I would have to stop driving and pull over. One time I almost fainted during a meeting and had to go to the clinic. This drug made me dizzy, lightheaded, feeling like I was going to pass out all the time, gave me the strangest head pressure/tingling feeling, heart-racing constantly. I will never ever take this drug again. Worst experience."

• Asscher
• Taken for less than 1 month
• December 28, 2014

Compazine (prochlorperazine) "I was in the hospital suffering from post lumbar puncture headache and nausea/severe vomiting. IV Zofran did nothing, IV Reglan did nothing, only the IV Compazine gave me relief. Granted as soon as it ran out I started up again, but at least it allowed me a few hours of peace to sleep."

• Bear
• Taken for less than 1 month
• June 27, 2019

Compazine (prochlorperazine) "I wish I could give this drug 0/10 stars. This is not a drug that I would give to my worst enemy--And I have tried MANY drugs for migraines! I was given this with the migraine cocktail in the ER, which also includes benadryl & toradol. I experienced extreme anxiety and restlessness. I wanted to rip the IV out of my arm and run out of the hospital... not that I could have done this anyways because it caused me to have extrapyramidal and dystonic side effects!!!!! When I got discharged from the ER, this was the worst night of my life. My friend had to sleep over because I was freaking out. The side effects lasted for 2 days."

• Izano
• Taken for less than 1 month
• January 8, 2020

"Was prescribed this for ongoing condition of vertigo to help with the nausea. I took two pills and it gave me the worst anxiety I have ever experienced. It felt like I wasn’t even in my own body, I lost my appetite for about a week, my heart rate was through the roof and it was a struggle to breath properly. I’m only 20 years old and it took me a good month to recover fully from this drug. Whilst my vertigo had gone the next day, the side effects were so much worse than the original problem."

• Miss
• Taken for less than 1 month
• May 30, 2018

Compazine (prochlorperazine) "I cannot believe all of these totally horrible experiences with compazine. I was given in my IV for severe nausea and I had absolutely no side effects what so ever. I have taken another one now that I am home before I went to bed, again no problems or side effects at all. Hard to believe so many people are having such severe reactions?"

• Kitak...
• Taken for 2 to 5 years
• January 31, 2014

"I suffer from occasional vomiting from acid indigestion brought on by major anxiety. I take Protonix daily for indigestion & also Buspar for anxiety which has helped drastically. However sometimes the anxiety is so extreme I will still get nausea & vomiting. That's when I go to my trusted friend Compazine. It lasts well past 8 hours & gives me time to relax & calm my anxiety (which is near to impossible to do while you are throwing up stomach acid every few minutes%u2026). I have also been prescribed Zofran which also works very well, but is a lot more expensive. I have not experienced any side effects with either medicine. Compazine has saved me more than a few times when I have an appointment I can't afford to miss & that I am anxious over."

• Patty
• Taken for less than 1 month
• May 16, 2019

Compazine (prochlorperazine) "It is absolutely horrible I went into the ER yesterday with a bad headache on one side they wanted to give me some cocktail with included compazine and Benadryl combined I said no, I should have done my research on compazine prior to getting it intravenously the worst mistake of my life I had shakes anxiety which I don't have the worst dry mouth of my life that I almost choked on my sugar pill I felt like it had been out in the desert for a year I could not keep my mouth moist fast enough. It has been almost 24 hours and I'm still not back to 100 percent yet. That drug is toxic I would never I don't care how much pain I'm in ever take that drug."

• dharr...
• Taken for less than 1 month
• March 4, 2017

Compazine (prochlorperazine) "I was given compazine through the IV for nausea and vomiting while admitted. It was an absolute nightmare that still makes me feel pure fear when I think about it. I thought I was going to die. At first, my legs just felt restless which I thought I was just having some anxiety, but then it really hit. I couldn't get my body to cool down, I started vomiting, then lost control of my bowels in front of the nurses. This lasted over six hours until they finally gave me something that knocked me out until it was over. I thought I was going to die. It scared both my partner who was there and myself to the point that I am now scared to take anymore medications fearing a similar reaction. They should really warn people about this drug."

• Mahbu...
• Taken for 10 years or more
• February 3, 2017

Compazine (prochlorperazine) "I was talking to my sister about my bad reaction to a medication I took 15 years ago called Compazine. I took this prescribed medicine while at home. I remember my experience like it was yesterday. At first I felt a twitching in my jaws. All at once, my bottom jaw started going to the right, and my top jaw started going to the left. I could not stop it and I could not talk. In fact, my jaw felt like it was trying to break off my face. I remember the emotional and physical pain. Me and my husband were both crying, because we both didn't understand what was happening! My husband ended up taking me to another clinic, and they admitted me at once. So BEWARE! Just from talking - I found out this same medication hurt my sister just last year."

• Hannah
• May 19, 2016

Compazine (prochlorperazine) "I took this for my extreme amount of nausea causing anxiety. It did wonders for my nausea! It was wonderful and like a miracle. Until the 3rd time I took it... I had the worst experience of my life. My jaw got locked and stuck to one side, my eyes got locked looking upwards and I couldn't move them, my jaw felt as if it was trying to break itself and was so painful . I ended up sticking my finger down my throat to make myself vomit up the drug. It continued to lock my jaw up off and on for the next 48 hours. Never again. Be careful of the side effects. Worked wonders for my nausea and vomiting, but I would rather be throwing up than experiences those side effects"

• MDay
• Taken for less than 1 month
• February 17, 2019

Compazine (prochlorperazine) "I was in the ER due to a severe migraine that couldn’t be controlled with my prescriptions that I usually take. They gave me Compazine for the nausea/vomiting. It was the most awful thing ever. I became so restless. I felt like I had to leave and go home. I couldn’t sit still, and I felt like I constantly needed to pace the room. I felt like I was going crazy, and like I was about to rip my hair out. (I didn’t.) I will avoid this medicine at all costs. I don’t even know if it helped the nausea/vomiting because it made me feel so weird."

• Zanar...
• Taken for less than 1 month
• March 27, 2021

Compazine (prochlorperazine) "Do NOT use compazine!! I went to the ER for a severe migraine that lasted a week. They put me on Compazine and within just a few minutes I was shaking uncontrollably, couldn’t keep still, and had extreme anxiety like if I didn’t leave the hospital RIGHT AWAY my entire life would just go down the toilet. This was the only time I ever ripped out an IV. I called the nurse in and I could only mumble “oh god what did you do to me” over and over again. After some of these other reviews, I count myself lucky that my symptoms only lasted a single night and the migraine did go away. But still I will never take it again!"