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Lyrica User Reviews & Ratings (Page 5)

Lyrica has an average rating of 6.4 out of 10 from a total of 930 reviews on Drugs.com. 53% of reviewers reported a positive experience, while 26% reported a negative experience.

Reviews for Lyrica

Commonly mentioned side effects
  • Jef...
  • Taken for 10 years or more
  • July 2, 2025

For Fibromyalgia "I have had fibromyalgia since I was 22 years old. I have been on Lyrica for 20 years, and it really helps with the pain. It works best if you take it every day and don't skip a dose when you feel less pain. I've noticed two side effects from the medicine: one, it makes you sleepy, and two, it causes me to have short-term memory loss. It's harder to remember things two, three, or four days later when I am on the medicine. I take 100 mg 3 times a day."

10 / 10
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  • Jen...
  • Taken for less than 1 month
  • October 30, 2015

For Neuropathic Pain "My Dr. just changed me to Lyrica 75mg twice a day vs 300mg of gabapentin 3x a day and Cymbalta 30mg 2x a day for neuropathy (not diabetic). I have only been taking it for 3 days and I can already tell a significant difference. My hands and feet have no burning pain, and I seem to have less numbness. I have also noticed that it helps tremendously with my anxiety. I was taking Xanax 1mg 3x a day, and now I only take it once a day if that. I seem to feel more relaxed and less anxious, so maybe this will actually help me stop taking the Xanax, which I've tried so many times in the past. So far, I am super impressed with this medication."

9 / 10
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  • msq...
  • Taken for 6 months to 1 year
  • August 6, 2013

For Neuropathic Pain "Works pretty well for nerve pain and numbness. I have degenerative disc disease along with several other cervical and spinal issues. I started at a higher dose that had too many side effects, but when my dosage was lowered, I had a lot of relief."

7 / 10
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Frequently asked questions

  • Bob...
  • May 27, 2016

For Fibromyalgia "Side effects are worse than Fibromyalgia pain. I've been taking Lyrica for two months. It was a miracle drug for the first few weeks. I've been living with Fibromyalgia for over 35 years and have tried everything. Anti-depressants, exercise, biofeedback, acupuncture, narcotics, you name it. So I was excited about the dramatic pain reduction from Lyrica. But now I have developed severe muscle weakness, headache, abdominal cramping, acne, and difficulty thinking clearly. I can barely hold myself up, and I can't lift anything over a few pounds. I have asked my doctor if I can safely stop taking it. I'm just waiting for him to return my call. I would rather just live with my horrible pain than take any more of these toxic drugs."

3 / 10
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  • Chr...
  • Taken for less than 1 month
  • July 24, 2018

For Neuralgia "I just started taking Lyrica 50 mg 2x a day for trigeminal neuralgia. Before I started, I was having awful facial pain, especially on the right side of my jaw and teeth. I thought I had some cavities or something. I was crying from being in so much pain. I went to the dentist, got an X-ray done, and there were no cavities and nothing wrong. So, I started doing my own research (googling my symptoms) and read about nerve pain. I immediately got in contact with my neurologist to come in and get seen. I also have epilepsy, chronic migraines, and the list goes on. When I picked up the medication from the pharmacy, I asked how long it would be before I could get relief, and the pharmacist said probably 3 or 4 days. I was feeling great after 2 doses of Lyrica. I am scared about the weight gain, so I'm watching how much I eat, but just not being in pain is so great right now!!! Thank you, Lyrica!!!"

10 / 10
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  • Bac...
  • Taken for less than 1 month
  • October 15, 2014

For Neuropathic Pain "I started taking this medication about a week ago. AMAZING! My doctor prescribed it for the pain shooting down my arm and hand from cervical and thoracic issues. I was writhing in pain at night, so much so I could barely walk. After just one dose, a total difference. I take just 75mg before bed. I do notice a feeling of drowsiness upon waking, but it is usually gone a couple of hours later, unless I take Tylenol or Motrin. One of the side effects I have had is swollen eyes and crusted eyes. I am very tired and need a nap. I find the pill seems to work for about 20 hours for nerve pain, and then it starts coming back."

9 / 10
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  • tri...
  • February 28, 2008

For Diabetic Peripheral Neuropathy "I love the drug, but I am experiencing excessive weight gain. I began the medication in November 2007. To date, I have gained 30 lbs. Some of my now fat clothes have gotten too tight. :( Has anyone else experienced this problem?"

10 / 10
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133 Report

More FAQ

  • dan...
  • August 9, 2013

For Fibromyalgia "I've been struggling with deep muscle and bone pain. After trying Vicodin, tramadol, gabapentin, and more - I can't even remember, my new doctor gave me a Lyrica sample. For the first time in four years, I was able to get out of bed with no pain. It's changed my life."

8 / 10
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  • Rus...
  • Taken for 2 to 5 years
  • August 4, 2019

For Neuropathic Pain "I've been on Lyrica for 4 years for nerve pain down my right arm due to nerve impingement at C7/T1. I'm one of those lucky people with minimal side effects. Can get a little forgetful (use phone calendar reminders), and hard to get up in the morning initially, but otherwise no issues. Also helped keep the migraines under control due to cervical headaches triggering a migraine. Was bed bound 4 out of 7 days. Now one migraine a month."

8 / 10
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  • mam...
  • September 1, 2015

For Neuropathic Pain "I was having terrible pain with sciatica. At times, I was in so much pain just walking in a shopping centre I just had to stop. Also, driving the car, my leg was in so much pain I had to lift it up with my hand to ease the pain. No medication I had taken stopped the pain, which was unbearable, and I couldn't sleep at night. My doctor prescribed Lyrica, and at first, I did not like it because it made my feet puffy, however, I went back on it with the prescribed dose of 150mg twice a day. Now I have to try to recall the pain because I have no sciatic pain at all with this drug. It also had the side effect of making me a bit 'dreamy,' which I rather like, but I do forget names and things I am saying, which I do not like. Can't have it all though!"

10 / 10
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  • Dus...
  • Taken for 1 to 2 years
  • May 23, 2014

For Neuropathic Pain "This medicine does seem to help quite a bit with nerve pain. I do tend to have an easily oversensitive nervous system. Lyrica makes me feel a lot better at nighttime so I can sleep. I take MS-Contin in the day and Lyrica at night. My life would be a lot less stable without Lyrica. I believe the best way I can describe what it does is slow down the pain signals so they are not as noticeable."

10 / 10
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  • TAL...
  • July 4, 2011

For Pain "Truly liberating to know that Lyrica helps alleviate my chronic pain. For over 30 years, my very misunderstood condition has been mistreated, and I myself much maligned. Using high dose opiates became my way to deal with it as they worked to a degree. BUT 3 years ago, Lyrica helped change my life. IF ONLY IT WAS AROUND A LONG TIME AGO. Lyrica works."

10 / 10
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  • TTT...
  • March 30, 2013

For Neuropathic Pain "I started taking Lyrica for pain from Hashimoto's disease. At first, I had a lot of energy. Then, I leveled off and the fatigue is back. The pain is about 85% gone! I did experience a huge emotional rollercoaster at first and even had suicidal thoughts for the first time ever. I figured it was just the adjustment period and gave it more time. It has been about 2 months now, and I just wish I could figure out if it is the Lyrica causing the fatigue. I ache too much without it to test the theory."

9 / 10
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  • Jam...
  • December 12, 2015

For Neuropathic Pain "I have a spine injury L5-S1 area. For the first 6 months, I was on every anti-inflammatory, and it made me sick. In addition, I was on a heavy dose of Tramadol with no effect on pain whatsoever, it just made me high. Then, Percocet only made me high and was very addictive. However, after reading about Lyrica, talking to my doctor, getting some, and stopping my flair-ups, it saved me. Lyrica reduced my pain by about 40% and stopped my flair-ups by about 80%. It acts somewhat like an antidepressant for me, making me a bit hyper (which is a good thing), but it kills my sex drive. I stopped it for a week, and it was hard on me as the pain and flair-ups came back. I rapidly built a tolerance to Lyrica, increasing my dosage from 100mg to 600mg. It also restored my hunger, and I'm gaining weight (a good thing). It's essential to realize that nothing but hard work and medication will reduce your pain, nothing can eliminate it entirely. I understand it can be disheartening, we all wish for a miraculous healing touch from our doctors. It's crucial to incorporate exercises at home, maintain a healthy diet, seek mental support, use pain medication, and seek guidance from your doctor. Dealing with chronic pain requires both mental and physical assistance, and above all, it's your determination that aids in your recovery."

7 / 10
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  • Im ...
  • Taken for less than 1 month
  • June 16, 2013

For Neuropathic Pain "I have been on Lyrica for about three weeks, and I feel that my experience may help. I have chronic nerve damage in my arm and sympathetic nerve damage. If you are about to begin the Lyrica ride, expect the following: you will be living in a cloud. I noticed a few reviews explained it as that, and I feel they hit the nail on the head. You literally feel drunk."

7 / 10
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  • Mis...
  • Taken for less than 1 month
  • February 18, 2019

For Fibromyalgia "My fibromyalgia has gotten worse the last 2 years, and I've also developed paresthesia in my feet and hands that causes burning and tingling. I was so tired of the pain and none of my doctors helping me that I was suicidal before Christmas 2018. That was before my new rheumatologist put me on Lyrica. I was to start with 75mg at night and then titrate up to an additional 75mg during the day (or take at night if it made me too tired). However, the 75mg alone has proven to be such a help that I may just stay there until I need to go up because the medication is pricey. I got a co-pay card from the Lyrica website, so I only had to pay $25. I don't care, though, it helps so much! I am no longer in so much pain!"

8 / 10
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  • Lon...
  • Taken for 2 to 5 years
  • June 14, 2017

For Fibromyalgia "Lyrica really has changed my life by allowing me to sleep at night without all the leg pain. Having both fibromyalgia and neuropathy is a lot of pain, but combined with my other meds, I no longer suffer from nerve pain."

10 / 10
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  • Poi...
  • July 28, 2016

For Neuropathic Pain "I took Lyrica for 8-9 months, then around the 5th month unknowingly it was Lyrica doing all kinds of bodily function damage, feeling unwell, swelling, cramping, kidneys, liver, and bladder hurt. Then I realized I no longer want to be poisoned, so I stopped taking it and it is hellish trying to get off. Wouldn't let my dog take it! Stay away from it! It's pure poison to your body and BRAIN as well. Very low functioning! It needs to be taken off the market!"

2 / 10
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  • Ms ...
  • Taken for less than 1 month
  • May 19, 2013

For Fibromyalgia "Diagnosed with fibromyalgia 6 years ago, I've tried many antidepressants and painkillers. I have been in withdrawal of Tramal and replacing it with Lyrica. I see it as my salvation when compared to some of the medications I have taken over the years. YES, withdrawal from any form of medication is horrific and with uncertainty and discomfort. I personally am prepared to go through this horrible time to give Lyrica its chance to work and improve my life, as I have seen an improvement already. Thanks to those who worked so hard to make this medicine for those of us who need it, know that your work is appreciated."

9 / 10
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96 Report
  • Bra...
  • August 26, 2015

For Fibromyalgia "This drug changed my life with unexpected benefits. I started taking it for a herniated disc and a lot of nerve damage. I started feeling pain relief immediately. It made me feel very high the first week, and I had to be careful how and when I would take it - 150mg 3 times a day. The high feeling eventually gradually dissipated. After a week, I noticed my wife smiling a lot. With great caution, I asked her why, and she said she likes how calm and relaxed I am. I'm naturally a very high-strung, intense person. I thought about what she said and noticed I actually was very relaxed, and things that typically set me off just didn't anymore. I then read about how the drug helps with anxiety. My insurance doesn't really cover it... I pay $50 for a month."

8 / 10
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  • tit...
  • Taken for 5 to 10 years
  • November 1, 2018

For Fibromyalgia "Lyrica has changed my life. I have worked in retail most of my life, and it entailed a lot of heavy lifting. As I got older, I started to get pain all over my body, my hands, legs, and back. Doctors gave me every drug you can think of, including narcotics, nothing was helping, and I was also getting very depressed. Finally, I saw a specialist and was prescribed Lyrica. Not only did it help me with the pain, but it also helped with the depression. I did gain 30 lbs, but I will take Lyrica over having pain and depression."

10 / 10
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  • Ann...
  • June 12, 2014

For Diabetic Peripheral Neuropathy "Lyrica is about as effective as opioids without the baggage that comes with the latter. Lyrica has its own side effects for me while working up to 450 mg/day, including a floaty, spaced-out sensation, INSANE appetite, and constipation - these side effects largely disappeared at the 2-week point. Pain relief was fairly quick, at about the third or fourth day."

8 / 10
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  • flo...
  • Taken for 1 to 6 months
  • February 18, 2014

For Fibromyalgia "I have found I have an increased urge to eat sweet foods. I have tried to control this by eating fruit. However, this does not stop the craving for sweets. Also, I have noticed an increased thirst and less urination. Further, I have been able to stop using morphine patches and taking Mersyndol Forte since starting Lyrica. The lessening of pain has enabled me to sleep better."

8 / 10
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  • Oll...
  • March 3, 2017

For Neuropathic Pain "I had an accident in April 2016. A riding lawnmower fell on top of me in a deep ditch. It knocked me out and caused severe lumbar spinal stenosis and pinched nerves. Up until this year, I was in a lot of pain due to the nerves being pinched by my spine. All this time, I have seen 3 doctors-really 4: one neurologist, 2 neurosurgeons, and an internist. No one even suggested Lyrica for my pain, except the neurologist who did the nerve conduction study. He said it worked for restless leg syndrome, which I also have. I got some Lyrica and tried it. It has brought me from a 10 pain level to a 2 or 3. I get up early now like I used to, I have the will to do things on my property, etc. I had lost the desire to even get out of bed. I wish I had tried Lyrica a lot sooner, it gave me my life back."

10 / 10
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67 Report
  • Har...
  • Taken for less than 1 month
  • February 1, 2019

For Neuropathic Pain "Biggest scam on Earth! I had suicidal thoughts and went into massive depression while using Lyrica. Lyrica has been found to be ineffective in numerous research papers and linked to depression and suicide. It does great in the market because of the phenomenal kickbacks Pfizer offers to doctors to push its sales (an expensive medicine with no generic alternative and claiming to cure a patient in extreme pain is a great way to milk the market). Pfizer spent $2 billion in marketing this drug by offering doctors and family free vacations, was found guilty and fined $1 billion by the US Supreme Court. PLEASE STOP USING LYRICA AND CHANGE THE DOCTOR WHO RECOMMENDED IT TO YOU! (If you refuse to believe me, do some research on Pfizer, e.g., 'Pfizer Pays $2.3 Billion to Settle Marketing Case')"

1 / 10
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