Lyrica Interactions
There are 284 drugs known to interact with Lyrica (pregabalin), along with 6 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 28 are major, 255 are moderate, and 1 is minor.
- View all 284 medications that may interact with Lyrica
- View Lyrica alcohol/food interactions (1)
- View Lyrica disease interactions (6)
Most frequently checked interactions
View interaction reports for Lyrica (pregabalin) and the medicines listed below.
- albuterol
- amitriptyline
- amlodipine
- aspirin
- atorvastatin
- baclofen
- clonazepam
- cyclobenzaprine
- Cymbalta (duloxetine)
- duloxetine
- Flexeril (cyclobenzaprine)
- furosemide
- gabapentin
- hydrochlorothiazide
- ibuprofen
- levothyroxine
- lisinopril
- meloxicam
- metformin
- omeprazole
- oxycodone
- pantoprazole
- prednisone
- Synthroid (levothyroxine)
- tizanidine
- tramadol
- trazodone
- Vitamin B12 (cyanocobalamin)
- Vitamin D3 (cholecalciferol)
- Xanax (alprazolam)
Lyrica alcohol/food interactions
There is 1 alcohol/food interaction with Lyrica (pregabalin).
Lyrica disease interactions
There are 6 disease interactions with Lyrica (pregabalin) which include:
- drug dependence
- suicidal tendency
- angioedema
- creatine kinase elevations
- peripheral edema
- PR interval prolongation
More about Lyrica (pregabalin)
- Lyrica consumer information
- Compare alternatives
- Pricing & coupons
- Reviews (925)
- Drug images
- Side effects
- Dosage information
- Patient tips
- During pregnancy
- Generic availability
- Support group
- FDA approval history
- Drug class: gamma-aminobutyric acid analogs
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.