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Lyrica for Fibromyalgia User Reviews (Page 5)

Lyrica has an average rating of 6.4 out of 10 from a total of 311 reviews for the treatment of Fibromyalgia. 52% of reviewers reported a positive experience, while 27% reported a negative experience.

Reviews for Lyrica

  • the...
  • Taken for 1 to 6 months
  • July 25, 2015

"I've had fibromyalgia for about 30yrs - I am 43. Endometriosis from ages 13-36, (a hysterectomy 'fixed' that;) clinical depression from abt 16, (break down at 28;) anxiety disorder; insomnia &/or severely disturbed sleep cycles for15-20yrs. AND I've needed a cane to walk for the last 2-3 yrs. FMS & depression compete for the title of "most debilitating." I've tried almst everything, (Cymbalta was useless.) The last 2 months I've been taking slowly increased doses of Lyrica. Currently on 150mg a day, (2× 75mg,) with a view to 300-400mg. I've had zero relief from pain, BUT nasty side fx. Almost no sleep. Worsened depression & anxiety. Terrible FMS type 'fog.' Flatulance! Cannot see this contiuing or improving. (Available on PBS in Australia.)"

1 / 10
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  • Diana...
  • February 2, 2013

"I have been on Lyrica for a week now, 150 mg only at night and have not felt this good in three years. I am move active. I have not gain any weight yet, but hopefully be as active as I am now I will lose weight."

9 / 10
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  • Monkey
  • December 31, 2016

"I wanted to share my experience in combining Lyrica and Neurontin for neuropathy symptoms; I've had fibromyalgia for 25 yrs. Neurontin was effective, but only at 1800 mg./day, which left me drowsy (fell asleep anytime I wasn't moving). My MD switched me to Lyrica (75 mg), but when I got to 3 per day, I rapidly gained weight - 10 lbs. in 2 wks! As a med student, I knew the two meds worked in a similar way and were metabolized similarly. I decreased the Lyrica to 1/ day, which stopped the weight gain, but didn't control the nerve pain, so I added back in one 300 mg. Neurontin per day (both at bedtime, to minimize drowsiness) - still not enough pain control. I added another Neurontin, and that was optimal for me. I take it all at bedtime."

10 / 10
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Frequently asked questions

  • Becca
  • Taken for 1 to 2 years
  • December 17, 2023

"I've tried everything through the years to manage pain, but most would only work with frequent breakthroughs and bad days. I have been on several antidepressants, NSAIDs, muscle relaxers, Ativan, and OTC medicines. Yoga, exercise, diet. Tried it all. It wasn't until I finally started Lyrica that I began to have more good days than bad. I have taken 300mg/day for over a year now, and I can finally get through my days like a normal person instead of struggling to work through pain. I don't think I'd be able to continue with my career without Lyrica - I used to wish that I could afford to work less. The only side effects I have encountered were tiredness and dizziness the first few weeks, slight weight gain (2-5 pounds) that never progressed, and occasional memory/word-retrieval issues. I'll take the side effects for what this medication has given me back in life. I am able to combine this with Zoloft for another diagnosis, and they do not cause any interactions."

9 / 10
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  • Sandymc
  • May 22, 2017

"I have suffered from headaches for years with relief with Excedrin. However, I was taking up to 8 at the onset to keep it from becoming a migraine. I'm really surprised that the Drs didn't tell my about "Excedrin abuse" since I told all that I was taking that much. However, when prescribed Lyrica for fibro pain, my headaches were gone to maybe 3 a week. So I highly recommend this for serious headache problems. Does help with Fibro pain. But, weight gain and dry mouth are my biggest side effect and is to the extent that I almost want to go back to 8 Excedrin a day. Hope this helps someone!"

7 / 10
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Are you taking this medicine?

  • Living
  • March 31, 2008

"I have had FM for 20 years, been on morphine, antidepressants, Fentanyl patches - you name it, I have tried it, but thank the Lord for Lyrica which I started in March 2008. It has made my life worth getting up for in the morning. I can do things I was not able to do for so long."

10 / 10
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  • Charl...
  • Taken for 6 months to 1 year
  • January 23, 2024

"I have fibromyalgia severely bad, and I have tried many different aspects even medical marijuana, but nothing helped like Lyrica did and it’s something I did not want to take at the beginning but once I did, I felt the remarkable difference within my body especially when I go through a flare-up. Yes, it is 1000% helpful and now that I am getting pains in my legs and feet. I know the worst is yet to come, so thank you for having Lyrica."

10 / 10
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More FAQ

  • Anonymous
  • Taken for less than 1 month
  • April 23, 2019

"I was prescribed 50 mg Lyrica twice daily and it helped slightly for a few days and then did absolutely nothing for my nerve pain/ fibromyalgia. I'm sure it works great for some people but for me the only thing it did was give me panic attacks, make me extremely depressed and altered my sense of taste. When I wanted to get off of it I got a new script for a wean and I had to phone lyrica to try to get to their patient assistance department since it is so expensive, even with the savings card and I should qualify for assistance. However I never got thru because their customer service insisted on interviewing me about my wean before they would put me thru to patient assistance. I shouldn't have to go thru 3 people to answer a yes or no question about assistance especially when I don't feel comfortable giving them my health records over the phone."

2 / 10
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  • LWSou...
  • April 27, 2017

"My doctor prescribed Lyrica for fibromyalgia. As I am very sensitive to medication, I was prescribed 75 mg at bedtime each night. The first month, I did feel better taking Lyrica. However, after about 4 months I began experiencing strange symptoms. I could not remember things. My brain was foggy. I wasn't myself and my pain returned. It was a no brainer, so I informed my doctor that I wanted off of this medication. I've been off Lyrica now for two months and my brain is back to normal. It was very scary to even think how little I was taking and what an impact it made on me. I am taking apple cider vinegar with honey every morning, exercising a little day, even if I don't want to, and resting when my body needs it."

1 / 10
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  • krism...
  • April 11, 2013

"This medicine worked pretty well for me. I didn't realize how well it worked until I went off of it before getting pregnant. The thing I didn't like about it though was that it always made me feel like I was in a cloud. My thinking wasn't clear. I would get dizzy. I didn't notice too much of a weight gain, but there was some. In the end, I chose to try a different med (Savella) after my daughter was born and have been happier with that. Still works and fewer side effects."

6 / 10
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  • Jll
  • Taken for less than 1 month
  • October 4, 2018

"I have Rheumatoid Arthritis and Fibromyalgia. I have only been taking Lyrica, 75mg twice a day, for a week. The first 4 days I felt "spacey", but that is going away. I immediately felt better. I have been on hydrocodone, then oxycodone. They were not helping much. My pain Dr did a cheek swab gene-drug reaction test. There were only two opiates that were compatible with my DNA. I've been on Nucynta, regular and ER for maybe 5 months. Still taking it and EC naproxen, Plaquinel. It was helpful for some of the pain, but not the nerve and muscle pain. I don't have any side effects so far from Lyrica. I will update if anything changes. All I need to say is I feel 85% better. I also feel better mentally and feel like doing things I haven't been able to til now. I'm taking a free trial, it hasn't been submitted through insurance yet. There is a discount card on website for $35 instead of insurance."

8 / 10
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  • Big...
  • May 16, 2017

"My doctor prescribed Lyrica for fibromyalgia, this was the worst medication I have ever taken! Within a few days, my anxiety levels were through the roof . I had other side effects too but I can't recall what they were now - it's been a horrendous year."

1 / 10
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  • Anonymous
  • March 7, 2008

"I have had fibromyalgia for 12 years and have been on high doses of morphine, Duragesic patches, methadone, and many other narcotics. I am now on 225mg of Lyrica twice a day and low doses of Opana. I feel like a new person, never thought it would ever happen. I feel like I did years ago, and I am 63 now but am able to do most of the things I was able to do before the fibro hit me. I can't work my old job as an RN, but I can do most things. Some days are better than others, but this is a great drug."

10 / 10
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  • Summe...
  • October 20, 2016

"Works pretty well for the pain, but having severe side effects (involuntary musclular movement involving jerking of legs and difficulty speaking, urinary retention and inability to urinate, dramatic weight gain of 30 pounds so far)"

6 / 10
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  • Alicat
  • January 10, 2016

"I started taking Lyrica about 8 months ago. In about 3 days I had felt a significant change. It was working great for my Fibro, but I also have spinal arthritis. It did nothing for that or my sciatica. Finally I was bumped up to high dose, but do to other things in life I had to stop because of financial difficulties. I couldn't even afford copays. So I'm on gabapentin and it barely works. If I could, I would get back on Lyrica! Thank you all for sharing your experiences!"

6 / 10
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  • Murr
  • June 14, 2017

"I started taking lyrica 25mg 2 weeks ago. I was sleepy day 1, took nap. Next day 25mg felt well and energetic. I'm combining low dose which a massage every 2 weeks. I'm interested in what others have to say about long term use at a low dose."

8 / 10
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  • Great...
  • Taken for 1 to 6 months
  • November 3, 2016

"Two attempts at treatment for fibromyalgia with Lyrica. Both had similar outcomes, in that the "cure" was worse than the illness. Side effects were overwhelming from the onset: increased fatigue, terrifying anxiety, tremors. In addition, this drug's efficacy was zero. I received no positive effects from Lyrica and discontinued use. Side note: I need to learn about illnesses that affect me and medications that I take or are offered to me. Doctors may mean well, but I need to know how they affect ME, not just what is printed in a package insert. And if a doc is not right for me, it's time to find her replacement."

1 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • July 10, 2012

"I have only been diagnosed for about a year now. I have completely lost my life due to fibromyalgia pain. My doctor started me on Cymbalta, which worked for awhile but then stopped, then put me on Lyrica without weaning me off Cymbalta....WITHDRAWALS hello. Had to start again and wean off while also taking Lyrica. The Lyrica seemed to help at first too, then wham just like everything else, stopped working....EXCEPT on weight gain and brain fog. I was a zombie. So now I'm worsening day by day even though I try to stay active have cut all caffeine, etc. because my doctors just don't believe pain medicines help and say there isn't much else they can do for me. Glad for the people it has helped."

1 / 10
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  • cat_b...
  • Taken for 1 to 2 years
  • January 26, 2013

"I started taking this at 150mg twice a day with some relief of pain, no side effects. I've recently increased to 225mg twice a day, which is the maximum dosage. I'm experiencing vertigo, sleepiness, and weight gain, but virtually no pain. My doctor feels the results out-weigh the side-effects and I agree."

9 / 10
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  • TMarie
  • June 4, 2016

"Lyrica has done a great job on my Fibro pain, but I am trying to get off it primarily due to side effects. It has caused mymetabolism to slow down so I can't lose weight, chronic constipation, and terrible gas. I can't go around anymore farting everywhere I go. I'll live with the Fibro pain."

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  • emily
  • Taken for 6 months to 1 year
  • August 20, 2015

"Lyrica did not work particularly well for me. I had previously taken Cymbalta 60mg for 7/8 years and was feeling that it was no longer as effective so my doctor prescribed Lyrica. I noticed a large amount of weight gain (which I would not have minded if helped the pain!) about 50 pounds over 6 months before it stabilized. After some time of taking the medication (9 months or a year I forget) I was always complaining to my doctor about pain and fatigue being bad so he switched me to Savella. I noticed a huge difference and I lost the weight!"

2 / 10
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  • Sherry...
  • April 18, 2017

"Been on this Lyrica 200mg for @ least 2 yrs I still have a lot of pain from having the disease of Fibromyalgia & Chronic pain along with arthritis they raised it up to the highest dose & still hurt very much & I agree with the lady above u do gain weight trying to hang in there! Hope they find something better for me & every one else Blessings to all "

5 / 10
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  • Anonymous
  • Taken for less than 1 month
  • July 29, 2012

"This medication left me unable to think coherently and I had difficulty talking. It was like being around a drunk. I had to stop it after a month because I work in a school and was unable to converse adequately with parents/students/staff. "

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  • foggy
  • Taken for 1 to 6 months
  • August 23, 2018

"Currently I have been taking 75mg twice a day of Lyrica. Not only do I have Fibromyalgia but I also have severe osteoarthits in my spine and multiple bulged discs cervical and lumbar. I had been treated in the past with Gabapentin and experienced too many side effects and it wasn't working so my doctor started me on the Lyrica. I have no insurance so was able to get it through the Pfizer assistance program. Since I have been on it there has not been any significant pain relief, I have gained 32 pounds in 4 months, and my memory has been terrible. I have struggled with concentration and I will me talking with my doctor about getting off of this medication. There has to be a better option out there for me. It may work for some people but in my case I have not seen much benefit to it."

2 / 10
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  • hope...
  • Taken for 2 to 5 years
  • October 23, 2013

"I have been taking it for about a year now, I only have one negative comment the withdrawl is horrible. I have no pain,I sleep well, my bipolar disorder is under control.my feet do swell every so often, I think it is a very good medicine to try .I also take 200mgs 3x a day the max dosage is 600 mg a day"

10 / 10
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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

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