Skip to main content

Prednisolone and Anxiety: What Users Say

Brand names: Millipred Orapred ODT PediaPred Millipred DP

Anxiety: mentioned by 4 users (8.3%)

Based on user experiences from 48 Prednisolone reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

headaches 12.5%
insomnia 12.5%
anxiety 8.3%
dizziness 8.3%
swelling 8.3%
itching 6.3%
mood swings 6.3%
moon face 6.3%
pain 6.3%
water retention 6.3%

Reviews for Prednisolone

Commonly mentioned side effects
  • MKa...
  • Taken for less than 1 month
  • October 8, 2019

For Immunosuppression "I took prednisone when I went to the doctor for flu-like symptoms (body aches, etc.) and was put on it for 5 days - 60 mg. I had had an allergic reaction to an antibiotic I was taking, so that's also why I was on it. By day 5, I was starting to get very anxious, and from there it just went downhill. I was crying every hour of the day for a week and a half after my last dose. I have anxiety normally, but this was next level, I have never felt that way in my life. And it wasn't like a teary cry, it was literally like someone had murdered my family member cry. I just don't think the anxiety is worth it. I can genuinely say I will never try this drug again. I'd rather die than take it, and I'm not being dramatic. To this day, I'm still trying to get back on track. If you have anxiety/depression, do not take this drug."

1 / 10
Was this helpful?YesNo
45 Report
  • Jen...
  • May 4, 2020

For Inflammatory Conditions "I was put on prednisolone for an inner ear problem caused by a hormonal imbalance. I'm very sensitive to medication, and I knew this when taking the full dose prescribed. I took 20 mg three times the first day and found that I could not sleep that night and had anxiety and a headache. I dropped down to 40 mg at 8 a.m. and 12 p.m. the next day and slept very well. No anxiety and no headache. I do take the pills with food. It has greatly decreased the inflammation I felt in the back of my head near my ear. I'm feeling better. Although, I'm on an antibiotic too. I was scared to take this after reading many poor reviews, but I'm so glad I did. I suffered for a long time before knowing it was my ear causing the problem, and I'm so glad I was prescribed this medication. I'm only taking them for 5 days though."

10 / 10
Was this helpful?YesNo
13 Report
  • TDE...
  • March 26, 2017

For Inflammatory Conditions "I have had a very stubborn sinus infection that just won't clear (6 months +). The doctor prescribed 7 days - 30 mg of Prednisolone. The first three days, I felt great. A lot of energy, clearer breathing, better sleep, however, after then it went downhill fast. My anxiety and panic skyrocketed after a year of being fine. I was shaking, weak-legged, dizzy constantly, my heart rate was through the roof (felt like I had drunk 10 coffees). I had worst sinus pressure and headaches as well. About day 5, it made my sinus problems worse as well, congestion and mucus production were in overdrive! Three days off them now and still haven't calmed down. Back to the GP we go :("

2 / 10
Was this helpful?YesNo
18 Report

Frequently asked questions

  • DM0...
  • Taken for less than 1 month
  • July 5, 2015

For Inflammatory Conditions "ENT prescribed me 1 x 25 mg daily for 10 days to treat tinnitus, in case it was caused by a blocked Eustachian tube. I had a very bad reaction to the steroid. I suffered from severe insomnia, depression, and anxiety. Psychologically, it caused me a lot of pain. I started tapering off the prednisolone after 7 days. My ENT advised to just stop and not taper, which concerned me as I was told to definitely taper, so I tapered on my own by going down from 25 mg -> 12.5 mg -> 6.25 mg. I still suffered from the same psychological issues for 10 days afterwards. Eventually, my GP prescribed me Valium. After taking 1 x 10 mg Valium, I found I returned to a normal psychological state (no anxiety, no depression, and sleeping fine). Tinnitus was not helped."

1 / 10
Was this helpful?YesNo
13 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.