Pazopanib User Reviews & Ratings (Page 3)

• l59
• January 28, 2018

Votrient (pazopanib) for Renal Cell Carcinoma "My mum is soon to be 90 and had never been in hospital only to have her four children. Mum got pneumonia and in November, 2017 was in hospital for 6 days. Diagnosed with pneumonia and an enlarged heart. Mid December, 2017 she came back to hospital with laboured breathing. Tests done showed collapsed lung due to fluid and to our shock later diagnosed with RCC, gone into Renal Artery and met to liver. By Wednesday 24th January 2018 she started on Votient, 2 a day. She already has white hair so I don't think that will change but she was taken off blood pressure tablets in hospital (which she had been on for 50 years) as her blood presssure was perfect. On Votient it has gone up again so am taking her tomorrow to see if they want to put her back on them. Mum has 20 great grandchildren and 12 grandchildren and wants desperately to be able to go to my sons wedding in March and her birthday is 1st May. The oncologist is confident that she will make both....Here's hoping"

• Debi...
• Taken for 1 to 6 months
• May 24, 2017

Votrient (pazopanib) for Renal Cell Carcinoma "Out of the blue, diagnosed after ct scan, stage 4 renal cell carcinoma, spots on liver also, spot on lung, adrenal glands involved, was told should expect to live 1-5 years. started Votrient 800 mg on April 13th and have not had a repeat scan yet. Side effects are horrendous to me. Scalp sore like a sunburn type feel, tender, have noticed hair thinning on top of scalp. Mouth is on fire to where I can eat few foods- puddings, water, ice cream mostly melted, soups. Some days mouth hurts so badI can not eat. Can not taste salt. A few days did not take votrient because I did not eat all day. Burning with urination, scalded. Burns with diarrhea also. Cracking of lips on each side of mouth. Keep telling myself it could be worse. God bless."

• CCR
• Taken for less than 1 month
• September 15, 2023

Votrient (pazopanib) for Soft Tissue Sarcoma "I started Votrient 10 days ago on 400mg. I feel no side effects. I was diagnosed one year ago with a rare soft tissue sarcoma called 'epithelioid hemangioendothelioma', stage IVB. We did 2 surgeries, which were very successful, but I still have some nodules on both lungs and liver. All nodules left have been stable for the last year, but one nodule on the upper right lung showed some growth, so that's why we decided to start the medication. We did a test using a live cell biopsy that showed good results for Votrient. I hope to see some good results on the CT scan in 3 months. I maintain a very healthy lifestyle; I only eat healthy meals, no processed food, no sugar, no gluten, or dairy. I also exercise, do yoga, attend dancing classes, and try to live my life as normally as possible."

• Jeff
• Taken for 1 to 6 months
• August 21, 2020

Votrient (pazopanib) for Soft Tissue Sarcoma "Stage 4 soft tissue sarcoma I was on 800 mg of Votrient. After 3 weeks the doctor took it down to 600mg because the side effects were too much for me. On 600mg they were still bad, but he said he couldn't go lower. After 3 months the cancer had grown and spread to my spine. Now I am having radiation on the spine then Chemo, I was told if I do nothing I have "weeks to months" left. If I do Chemo. "months to a year" some choice huh? I'll try the Chemo, but if the side effects are not worth it, I'll stop"

• Sunray
• Taken for 1 to 6 months
• September 10, 2020

Votrient (pazopanib) for Renal Cell Carcinoma "I am a 72 year old female. Diagnosed 2010 large kidney tumour. Radical right side nephrectomy. 2014 recurrence of cancer in left kidney and remaining adrenal gland. Tumours were progressing very slowly. Started on 800mg dose in January 2020. Reduced to 600mg after blood pressure spikes. By mid March all tumours had shrunk by 5mm. Due to Covid-19 treatment put on hold until mid July. I have a scan every three months and am due for my next one in October 2020. I am fortunate to be free from side effects up to now and I feel I’m lucky to have the best care through our NHS in the United Kingdom."

• Tamas...
• January 3, 2017

Votrient (pazopanib) for Renal Cell Carcinoma "1/3/16. Was told had cancer bottom of kidney and it got large Dr. Said and is pressing into spine. Was on voltrient about 2 1/2 months and scan showed tumor size had not changed. After taking voltrient about 5 months I got very sick and could not eat or drink about 10 days. Did lot of vomiting. Stomach hurt for many days. Need to ask Dr if I should get back on it (mass must shrink a lot Dr says before they would consider surgery). This has been very scary as mass pressing and causing tightness twisting of left leg but I'm doing lot of praying for self and all cancer patients. We desperately need cures. I get scans Jan 16. "

• Bose...
• Taken for 1 to 6 months
• February 5, 2017

Votrient (pazopanib) for Renal Cell Carcinoma "I have undergone radical nephractomy of my left kidney in November, 2014 with staging T2 N0 M0. Doctor said that I am now ok. During 2015 I have undergone quarterly check up by USG of abdomen and chest X Ray. In November 2015 CT scan of thorax and done and found two suspicious small nodes in left lungs but positionwise very small. Next scan done after six months, there was no change in size of those nodes or new growth. Pain started in left shoulder joint and in back since October, 2016. Went for CT scan followed by bone scan, which detected tumors in left shoulder and D4 spine, also increase in size of lung tumors. mRCC confirmed by biopsy. Started Votrient 800mg daily from 14th December, 2016. No major side effect except testlessnes"

• twh
• Taken for less than 1 month
• September 10, 2018

Votrient (pazopanib) for Renal Cell Carcinoma "RCC Stage 4 - Dec 2015 Unfortunately, cannot comment on efficacy of Votrient; was only on it for about a few weeks. Yeah, the gastro side effects started on about day 3, but it was the fevers that drove me to the hospital. Liver enzymes thru the roof. Was taken off med immediately, followed by a 3 week recovery period, then placed on Cabometyx (which Dr wanted me on in the first place). Cabo has worked wonders for me - into 15th month now - no side effects, dramatic reduction in tumors. Best Luck to you all"

• sre
• April 14, 2017

Votrient (pazopanib) for Renal Cell Carcinoma "My husband's left kidney was removed in March 2015 . No signs of cancer for one and a half years. In October 2016 he had cough and lower back pain. Did PET CT and found mets in lungs and spine . Started taking votrient since December 2016. After 3 months tumours in lungs are found shrinking. Major side effects are vomiting ,muscle and bone pain. Nowadays he is full time on bed due to muscle pain. Acid reflux is overcomed with Pan D . We are hoping and praying for positive results."

• Faith
• Taken for 1 to 6 months
• April 4, 2019

Votrient (pazopanib) for Renal Cell Carcinoma "Votrient nearly killed me by attacking my liver. I tried it twice. First time was for 4 weeks. During that time I had just about every side effect possible change in taste, diarrhea, white hair, tiredness. I finally had brick red urine and turned yellow as it attacked my liver. Found out side effects were so bad because a previous cancer drug, Opdivo, was still in my system. After 6 weeks of steroids, I tried Votrient again. This time, I got tired and had a fever within a week. Blood test showed it was attacking my liver once again. I was back on steroids. It did reduce the size of my tumors while one it, but was killing me by attacking my liver."

• Tiny...
• July 18, 2015

Votrient (pazopanib) for Soft Tissue Sarcoma "Hello Group, I just started Votrient 3 days ago, I have no side effects at all. I've felt great the past several days, just like my old self before I was diagnosed with a 11.2 cm tumor in my pelvis that was surgically removed in Feb of 2015. However the leiomyosarcoma mets to my liver, lung and I was told bones. After 6 treatments of Gemszar and taxatere the liver and lung mets spread and grew. I was sent to another hospital for Phase II trial trial drug to build the immune system charging the T-cells to go after the caner, while Dixol chemo attack the cancer. The Dixol could only be used 10 due to possible problems with heart pump. I said no thanks, thats when I asked what else they had so I was put on Votrient."

• dku
• December 19, 2015

Votrient (pazopanib) for Soft Tissue Sarcoma "My mother went on this wonderful drug and it was bad, it burnt and blistered this inside of her mouth and throat to the point she could not eat solids anymore. She lost all her strength to the point we had to carry her to the bathroom, and finally she lost her life."

• Sunray
• Taken for 1 to 2 years
• May 1, 2021

Votrient (pazopanib) for Renal Cell Carcinoma "Update.... on Votrient 800mg the since January 2020 with short period of treatment paused because of the pandemic. I resumed July 2020. Only side effect is elevated blood pressure ( controlled ). Latest scan showed dramatic shrinkage of RCC mets in remaining kidney, pancreas and adrenal gland. Also, lung mets no longer visible on latest scan. I feel very fortunate that this drug is working for me. My thoughts are with you all. Keep fighting."

• SSir
• August 28, 2017

Votrient (pazopanib) for Soft Tissue Sarcoma "I am on Votrient from 1st Jun and yesterday had my first Scan (3 month on Votrient, 800mg dose). It has shown the marginal increase in the size of the tumor but SUV uptake has gone down from 4.6 to 2.7. As per my doctor, the tablets are working and we will continue the same. Is it really working?"

• Lee
• Taken for 1 to 2 years
• June 11, 2020

Votrient (pazopanib) for Renal Cell Carcinoma "January 2017 left kidney, adrenal and 5 lymph nodes removed. 45 weeks into a trial came back in t9 vertebrae cleaned out. 2019 January started 800 mgs bad side effects went to 600 now 1and 1/2 years spot on left lung shrinking right adrenal sight reduced. Occasional diarrhea white hair. Medical marijuana helps with appetite and nausea, sleeping and anxiety. I will stay on until it stops working."

• Manny...
• Taken for 1 to 6 months
• January 26, 2016

For Renal Cell Carcinoma "I have had metastasis cancer for 9 years Had my kidney removed 2006. 4 years later my 3 left ribs removed , Jan 2015 my spinal code had an Operation done to remove cancer again. Then Sept 2015 it came back again I stay positive ,Sept 2015 this time my consultant put on 400 pazopanib and 3 weeks later 600 this dose. I could not handle all sorts of side-effects Went off for 7 day .back again on 400 .3 weeks then as soon as it got to the stage I could not handle it . I stopped for 7 days Jan 2016 pet scan . BIG DAY all CLEAR no sign of cancer I m on 400 for one more year 7 days ON 7 days OFF I have side effects but not that bad To all my friends have faith in PAZOPANIB IT WILL WORK NO PAIN NO GAIN"

• Renee
• February 22, 2021

For Soft Tissue Sarcoma "Hi, May 2016, I was diagnosed with metastatic mesenchymal chondrosarcoma. The mass was in my left fibula, and I took two different chemotherapy treatments (doxorubicin + Ifosfamide) followed by surgical resection Oct 2016. Devastated! Cancer metastasized in my lungs, and abdomen area. I got a bone scan done, blood work done, then started chemotherapy, using doxorubicin. I maxed out on doxorubicin, took a break and started caelyx chemotherapy. Got a scan. Found out this was not working. The mass in my left retroperitoneal was now 9 x 7 cm. The doctor gave me five high doses of radiation October 1, 2020. I started the pazopanib October 27, 2020. 600mg/day, had a scan February 17, 2021, saw the doctor February 22, 2021. OMG!! Thank you Pazopanib for keeping this metastatic disease stable. Tumors have shrunk, and others are stable. I will remain on 600mg of Pazopanib and will see the doctor in three months, for another scan and update."

• meo...
• Taken for 6 months to 1 year
• August 4, 2017

Votrient (pazopanib) for Renal Cell Carcinoma "Update-tolerating Votrient 400mg. Last 2 scans status quo. Diarrhea controlled with immodium. Pattern of a couple good weeks followed by fatigue and general awful feeling. Medicinal marijuana has been a godsend for these bad times. Almost like setting a reset button both mentally and physically. Only do it when I feel awful and won't be leaving the house."

• 3...
• October 17, 2021

Votrient (pazopanib) for Renal Cell Carcinoma "I was diagnosed with renal cancer 6 years ago. My left kidney was removed. I received no chemotherapy or radiation due to the fact it was ineffective on a clear cell carcinoma. I had 3 nodules on my lungs at the time it was diagnosed. 5 years later a CT scan showed the 3 nodules grew and two more appeared on my right lung. A wedge section was removed from my left lower lung. The Metastasis was confirmed to stage 4 cancers. After 2 opinions I tried a combination of Keytruda infusion and Inlyta tablets. I had a severe reaction to the Keytruda thankfully the doctor and nurses saved me. I had several options and went for Votrient. I have had no serious side effects. My blood pressure became elevated but was brought under control with an increase of blood pressure medication. I just had a CT scan. The 3 remaining nodules shrunk and 1 disappeared. No other signs of cancer. I am a new user but so far I think this drug is a miracle."

• Clem
• April 25, 2020

Votrient (pazopanib) "I started on Votrient in mid Janaury for Nueroendocrine Tumor and have been on for a little over 3 months at 600mg day. It was rough at first. Felt bad , upset stomach, diarrhea, mouth sore, food tasted bad and all my hair turned white. Lost weight as well. My blood counts were not affected and only slightly raised my blood pressure. I have toyed with when I take the medicine to try to mitigate symptoms. A couple times I've stopped for 4-5 days due to horrible diarrhea. It would clear up after 24-48 hours of stopping the medicine. My taste would return as well. After 3 months I now take the medicine around 3AM or when I wake up to use the restroom in the night, when my stomach is most empty. This made a huge improvement. I always take 2 Imodium before breakfast , 1 before lunch and 1 before dinner. This leveled out the diarrhea. Other than my white hair, all other symptoms have mostly subsided and I am able to carry on as normal. CT scan coming up next month."

• tony
• April 22, 2015

For Renal Cell Carcinoma "One year of use. Experienced all common side effects. Consult with a nutritionist for weight loss. Ensure has been helpful for me. Dermatologist and podiatrist for hand foot syndrome . Med to control blood pressure . Imodium for diarrhea. Basically stable at this time. Votrient is the first line treatment , do everything you can to continue treatment. Good luck."

• Anonymous
• July 24, 2016

For Renal Cell Carcinoma "My husband started 800mg Votrient 12 months ago 3 months post right renal nephrectomy with grade 4 renal cell carcinoma nodules in both lungs. CT scans 3 months later showed all nodules had shrunk, last 3 CT scans have revealed no change and he is stable BUT he is suffering from massive bouts of diarrhea as in some days / nights 10 or more times, he finds drinking the required amount of water makes him nauseous but he looks dehydrated, pale and is lethargic. Because of the urgent diarrhea he is always worried about going places unless he knows where he can rush to the toilet so he tend not to go far so this really impacts his life, he also has vomiting at times. His specialist only says to take anti diarrhea tablets and prescribed Maxalon."

• Kiwib...
• Taken for 5 to 10 years
• March 9, 2021

Votrient (pazopanib) for Renal Cell Carcinoma "Using Votrient Jan 2013 until July 2020 Had right kidney removed Nov 2011 on diagnosis of my cancer. Metastasised in my submandibular and parotid glands in Sept 2012 starting Votrient Jan 2013. SE’s appear to improve over the years, main issue was blood pressure and diarrhoea. I stopped Votrient to try SRT which appears to be working."

• Des2e
• Taken for 1 to 6 months
• December 5, 2016

For Renal Cell Carcinoma "Had radical nephrectomy Aug 2014 and I was clear until Jan 2016 when spots found on both lungs. Had ops to remove the cancer on lungs (big mistake). Cancer returned within 6-8 weeks. Started Pazopanib 5 mths ago. It's working!! Lung spots have shrunk. Side effects seem to come in waves for me. I'll have a few weeks of normal bowel then I'll have a week or so when it's bad. Hair has turned white (I'm 47). Bad taste in mouth, I've lost weight (10lbs), appetite comes and goes but it's mainly not there. Ulcers in mouth have gone but can't get rid of the ones in my throat. Blood pressure is normal. I feel tired at the end of the day (earlier than usual) but no real fatigue. Overall I'm feeling good and still working. Keep fighting all, God Bless"

• Anonymous
• December 27, 2021

Votrient (pazopanib) for Renal Cell Carcinoma "My husband had a nephrectomy of his left kidney, it had spread to his left testicle and had the testicle removed as well. Before the operation, the surgeon said that the mass had been slow growing for roughly ten years. He is 67, and in mostly good health outside of the cancer. It has been a year and a half on Votrient. The first dosage was too high and caused him a few hospital visits to stabilise his liver function. Now he is on half that dose, the only prominent side effect is the occasional nausea, fatigue and vomiting/fainting spells. Of course his hair has also gone completely white. He is very thin and struggles to put on weight but has a healthy appetite. It seems that this dosage is working, his cancer cells have shrunk. He goes for a PET scan twice a year and has been clear so far. In 4 months will be 2 years since diagnosis. So far the medication is working. The diet seems to be the trickiest part and I would recommend that you see an expert dietician. A specific diet is NB."