Zenpep User Reviews & Ratings

Zenpep has an average rating of 7.7 out of 10 from a total of 16 reviews on Drugs.com. 69% of reviewers reported a positive experience, while 19% reported a negative experience.

Condition	Avg. Rating	Reviews	Compare
Pancreatic Exocrine Dysfunction	7.7	12 reviews for Pancreatic Exocrine Dysfunction	64 medications
Chronic Pancreatitis	7.0	3 reviews for Chronic Pancreatitis	69 medications
Cystic Fibrosis	10.0	1 reviews for Cystic Fibrosis	104 medications

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Reviews for Zenpep

GZK...
Taken for 2 to 5 years
April 21, 2020

For Pancreatic Exocrine Dysfunction "Like my mother, I have had a duodenal ulcer, heartburn, and symptoms of EFI and steatorrhea for many years. Otherwise, I don't have pains, and I don't know if I have pancreatitis or CF. Without medicines, I would have 3-5 bowel movements every day, and it is extremely painful when I travel, which I do very often. So I started to take Zenpep, which is very effective without any obvious side effects. When I travel, 3-4 capsules of 20,000 units (the green capsules) with a meal will keep me safe for most of the day. But the worry about the side effects of long periods of usage pushes me to find alternative medicine. Luckily, I found that by chance, the non-prescription 300-400 mg capsules of Nattokinase (3-4 x 2000 FUs) with a meal have the same, if not better, effect to keep me dry for most of the day. Hope it helps anyone who may need it."

9 / 10

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54 Report

Sue...
Taken for 1 to 2 years
May 22, 2017

For Pancreatic Exocrine Dysfunction "I was diagnosed 2 years ago with stage 4 pancreatic cancer. I have had chemo and radiation, and I am doing very well. When first diagnosed, I was on Creon. I had no side effects, but wanted something a little less expensive, so my oncologist suggested I try Zenpep. It works great, as long as I don't forget and skip a dose. When I skip a dose, all my symptoms come roaring back: gas, pain, cramps, and loose bowels."

9 / 10

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47 Report

Wal...
Taken for less than 1 month
January 6, 2022

For Pancreatic Exocrine Dysfunction "I had unpleasant side effects with Creon, and an abdominal tenderness that lasted almost three years, so I quit taking it. My specialist suggested I try Zenpep. It works for me better, and the abdominal tenderness subsided quickly. I have experienced no side effects so far."

10 / 10

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19 Report

Frequently asked questions

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Anonymous
Taken for less than 1 month
November 8, 2023

For Pancreatic Exocrine Dysfunction "Just been diagnosed with pancreatic insufficiency. Was prescribed Zenpep two weeks ago. Started on 1 before every meal and snack. Just increased to two before meals and one before snack. Have seen a big improvement. Praying that it continues. Would like to find a diet program specifically for this condition."

10 / 10

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6 Report

Anonymous
January 6, 2017

For Chronic Pancreatitis "This medication works well for me, and I had no side effects. The monthly cost is so expensive! $1,875.72 monthly without insurance! With little to no help from the pharmaceutical company. When my insurance will pay for it, it's $240 monthly."

10 / 10

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24 Report

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Nan...
Taken for 1 to 6 months
February 6, 2023

For Pancreatic Exocrine Dysfunction "I was experiencing diarrhea 6 or 7 times a day, had cramps, and a rock-hard stomach and bowels. I had sleeve surgery 8 years ago, and my gallbladder was removed about 30 years ago. I was prescribed Zenpep one month ago and feel like a new person. Bloating, stomach pain, and diarrhea are gone as long as I take it with every meal. If I eat without taking it, the symptoms return. I am glad I have good insurance, as this medication costs $1,500 monthly, and I pay $30 for 2 months. It really does work well for me."

10 / 10

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8 Report

Bla...
Taken for less than 1 month
February 6, 2020

For Chronic Pancreatitis "Started using Zenpep. No side effects, but honestly, it does not work. I've been in pain ever since I started taking it. I take it during each meal, and I am in pain. Pertyze is what really works for me, but my insurance does not want to cover it. It sucks that we paid too much for insurance, and I have to beg for my meds. Actually, it's the only one I take. I eat well - I gave up sweets, red meat, and coffee, not too many carbs, but I hurt. I go on liquid diets for 3 days, if not more. As soon as I eat, there is my pain again with these pills."

1 / 10

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15 Report

Ron...
Taken for 2 to 5 years
December 9, 2020

For Pancreatic Exocrine Dysfunction "Using Zenpep has made a significant difference in the way I feel having pancreatic exocrine dysfunction (PED). Without this medication, I have a difficult time getting through a day without gastric issues."

9 / 10

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10 Report

deb...
Taken for 1 to 2 years
August 29, 2023

For Pancreatic Exocrine Dysfunction "Doctors prescribed Zenpep with meals and snacks. I pay $25 for 250 pills every month for 5 months, and then all my scripts are free for the last 7 months of the year with my insurance. This medicine works wonders. I'm so grateful. It helps with my acid reflux and gas. If I forget to take it, I realize it for sure I will start getting symptoms immediately. The doctor prescribes the max dose, so I will never run out. Forever grateful."

10 / 10

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2 Report

Cru...
Taken for 10 years or more
August 28, 2020

For Cystic Fibrosis "I've taken Zenpep for most of my life. I take 5 caps with meals and snacks because I have fat in every meal. It works great and the only time I've had an issue is if I had an extra fatty meal and didn't take an additional capsule. I recommend Zenpep to anyone with CF."

10 / 10

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2 Report

Anonymous
April 3, 2012

For Chronic Pancreatitis "Zenpep works great for me, however, the cost of the pills is ridiculous!"

10 / 10

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66 Report

Jan...
Taken for 6 months to 1 year
November 10, 2024

For Pancreatic Exocrine Dysfunction "Works well, but too expensive. I'm 79, and a $150 copay is more than I can afford."

7 / 10

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1 Report

Joe...
Taken for 2 to 5 years
July 21, 2023

For Pancreatic Exocrine Dysfunction "This medicine helped with my EPI symptoms but I experienced side effects such as dizziness, high anxiety, fatigue, and dry mouth, so I am currently looking for another alternative."

6 / 10

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6 Report

Jan...
Taken for 5 to 10 years
January 28, 2021

For Pancreatic Exocrine Dysfunction "I have been taking Zenpep for the past 10 years after having pancreatic cancer. It works great but is very expensive."

9 / 10

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9 Report

Anonymous
June 13, 2022

For Pancreatic Exocrine Dysfunction "i have been taking Zenpep for 3 weeks and I see no improvement."

2 / 10

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5 Report

CWa...
Taken for 1 to 6 months
August 3, 2020

For Pancreatic Exocrine Dysfunction "Zenpep Did not do anything for me"

1 / 10

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3 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.