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Opana for Pain User Reviews

Opana has an average rating of 8.0 out of 10 from a total of 78 reviews for the treatment of Pain. 77% of reviewers reported a positive experience, while 9% reported a negative experience.

Opana rating summary

8.0 average rating out of 10

78 ratings from 83 user reviews.

Compare all 1446 medications used in the treatment of Pain.

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21%
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Reviews for Opana

  • Anonymous
  • Taken for 6 months to 1 year
  • December 9, 2012

"I have cervical stenosis, bulging discs, and neuro issues resulting from them. I have been on Fentanyl patches, Oxycodone, and huge doses of Morphine ER with IR for breakthrough. I thought my pain would never end, and it was not only debilitating, but depressing to the point of, although not suicide, definitely not wanting to get up in the morning and wishing I could just die. When I moved and got a new Pain Management doctor, he questioned many of my old doc's decisions, but above all, he changed me onto Opana 30mg ER twice daily with 30mg IR Morphine for breakthrough 3x day. I feel more alive than I have felt in at least seven years. I am awake, I am alert, and I am functional, which is more than I had come to expect. Zero side effects."

9 / 10
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  • Dos...
  • Taken for 1 to 2 years
  • December 21, 2017

"I was switched to Opana ER after OxyContin stopped working for my chronic nerve pain. Opana ER gave me at least 12 hours of relief, no high, and I took much less breakthrough meds. When I went to refill it a few months ago, I was told Opana ER is no longer available due to complications addicts are getting from injecting it. I am very annoyed that the FDA prioritizes abusers over legitimate, responsible pain patients."

9 / 10
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90 Report
  • sma...
  • Taken for 10 years or more
  • August 31, 2013

"I have been on MS-Contin for 15 years. In that time, only one dose increase! I take 2x60 mg daily. Every 2-3 months, my doc changes medicine. I used to be able to get Opana, 40 mg 2x per day, and it worked great! Even better was Efalgo, 16 mg 3x per day. 2 in the morning, one at night. Now, insurance will not pay for either. The only medicine I can tolerate is Opana, 80 mg 2x per day, and they really don't work well. It is so frustrating that the medicine that is the hardest to tamper with, Efalgo, is the hardest to get and most expensive! If I don't switch every few months, I build up a tolerance. I suffer from degenerative disc disease in my lower back, arthritis, etc."

8 / 10
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117 Report

Frequently asked questions

  • Anonymous
  • September 6, 2012

"I have been on Opana for 2.5 years and I never felt better. I take it 2x a day and oxycodone 30mgs 4x a day. I am 55 years old and with my medicines, I can do things like a 20-year-old. The best pain medicine ever. I have been on different pain medicines for 18 years."

10 / 10
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113 Report
  • Anonymous
  • August 5, 2009

"Was on OxyContin 160 mg every 12 hours for 4 years and had tried Opana at the same dose last year WITHOUT BEING TOLD TO TAKE ON AN EMPTY STOMACH, so when my new doctor changed me, at first I was scared and skeptical. However, 25 days on 40 mg Opana every 12 hours ON AN EMPTY STOMACH and I am AMAZED. I believe if we increase the daytime dose a tad, I will feel better than I have in 18 years, so anyone who didn't have a good experience with it needs to think if they ate with it. My doctor said if there is ANY food in your stomach, the food absorbs part of it and it doesn't get into your system as well, and it WILL NOT WORK FOR THE 12 HOURS IT SHOULD. I saw people making both statements, so I hope this will help others."

10 / 10
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115 Report

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  • dee...
  • Taken for 1 to 2 years
  • April 5, 2013

"Crushed and bulged discs in cervical region, but I refuse to have spinal fusion due to mixed results and incredibly invasive surgery. Was on 3-30 mg Oxycontins with 4 x 10 mg oxycodone. I can't take anything with NSAIDs in it because I had Hepatitis C, which is gone after 11 months of interferon and another medicine. The oxy combo was working fine until suddenly it became impossible to get the scripts filled. Pain management doctor switched me to 2-30mg ERs a day and three Opana 10 mg IRs a day and I have no side effects, works great."

9 / 10
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92 Report
  • Anonymous
  • April 17, 2008

"This is a wonderful pain pill. I tore my sacroiliac and could barely walk because of the pain. I have a high tolerance for pain medications and have tried pretty much everything, and this one surpassed everything I tried, and I had no side effects."

10 / 10
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118 Report
  • cc ...
  • April 21, 2013

"My experience with Opana was great. It really gave me back at least 95%. After 3 failed back surgeries on my disc low back along with both knees which my knee surgeries were helpful. I also broke my back at the same time along with my neck injury which I was diagnosed with an extreme strain of my neck. My doctor gave me a 50% chance of success so I decided not to have and live with the pain. Although when Purdue Pharmaceuticals decided to completely change the formula when making the 40mg Opana, my life changed for the worst. I haven't been the same since. Believe me because I have tried every medicine on the market since 1993."

10 / 10
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84 Report
  • You...
  • January 13, 2013

"Been taking Opana for about 4 years now. It's the best medicine I have ever taken. I folded up my neck in an ATV accident. Have a failed 4-level fusion with steel plate and 4 bolts 1/4', 3 discs removed. Also have 5 deteriorated discs, and two more spinal surgeries since the first one. I have had to increase my dose to 40mg every 12 hours or so, and up to 6 IR 10mg each day. Since the pink 10 IRs have been off the market, the white generic 10 IRs are not the same. Take this on an empty stomach for best results. And to the one patient in a previous comment who was trying to get his nerve up to ask the doc to reduce his dosage, I would say it was really in his own hands. Reduce it yourself if you really think you don't need it."

10 / 10
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83 Report
  • Alf...
  • Taken for less than 1 month
  • March 20, 2015

"Male, mid-30s, 2 herniated lumbar discs, 3 pinched nerves, bone spur, stenosis. I have been on pain meds for the last 10 years, and Opana is by far the most effective pain med I've ever tried, and believe me, I've been on everything. Most recently, I was on OxyContin 20mg 1x a day and Oxycodone IR 20mg 5x a day. The problem with Oxycodone is that it has a very low half-life of 3-4 hours and is very addictive because of the short duration of action, you find yourself 'chasing the pain'. I suggested Opana to my PM doctor as I heard good things about it, best pain relief I've had in years! I take Opana ER 40mg 2x a day and Opana IR 10mg 2x a day PRN for breakthrough pain. This med is a wonder drug for those in 24/7 chronic pain!"

10 / 10
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71 Report
  • Anonymous
  • February 20, 2012

"I have had 24/7 severe headaches for 7 1/2 years due to a condition I have called occipital neuralgia. I have tried every kind of pain medicine and preventative medicine out there. Nothing worked! I am on 40mg of Opana 3x/day, and it is wonderful. I can function and work and play with my kids and be out in the sun for the first time in 7 years. This totally keeps my pain under control. I love it. I highly suggest that anyone with chronic severe pain try it. It works."

9 / 10
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86 Report
  • jim...
  • January 31, 2015

"I have degenerative disc disease, and Opana is the best pain medication that I have ever used. I have tried them all, and I take 2 20mg a day, 1 every 12 hours. It usually takes about 20 to 30 minutes to take effect, but it works!!!"

10 / 10
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70 Report
  • Anonymous
  • July 18, 2008

"This is one of the best drugs I have taken. I am able to do things I need to do. I can walk and clean house. Before taking Opana, all I could do was lay on the couch. I have rheumatoid arthritis, fibromyalgia, and Hepatitis C. This is the only drug that has ever helped me."

10 / 10
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82 Report
  • sex...
  • May 17, 2008

"I have had a lot of back pain for a few years, but since my doctor has put me on Opana, I have never felt better. I can go about my life without the worry of being in so much pain at the end of the day. What a relief it has been. A pure Godsend."

10 / 10
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77 Report
  • Mau...
  • April 10, 2017

"I have been on Opana ER 60 mg 3x a day for over a year now for chronic back pain. It is wonderful. Nothing has ever worked for me like it has. Not fentanyl patches, not oxys, nothing. I suggest any of you have a genetic test done by your pain doctor. I did. It allows your doctor to be able to tell what pain meds work for you the best. It isn't always about what med is the strongest, it's about what your body will use."

10 / 10
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43 Report
  • kjc...
  • Taken for 1 to 6 months
  • March 11, 2017

"Has been a lifesaver to me. I have a very long history with trauma and it has caused me a lifetime of serious pain: CRPS, fibromyalgia, PTSD. All my doctors had said the pain was 'in my head,' and hearing someone who SHOULD understand that you can have unimaginable pain due to trauma combined with other neurological and psychiatric issues. Thanks to my psychiatrist for prescribing this for me. It's helped with my depression, anxiety, and insomnia as well. My doctor and I have an incredible bond... A bond that has taken years, decades, to build the most respected form of trust. I DO NOT MESS WITH NOR USE MY MEDICATIONS FOR ANYTHING OTHER THAN WHAT I'M PRESCRIBED. I keep my RXs to myself and hidden well. Do not mess with medicine. NOT INTENDED FOR RECREATIONAL USE, EVER!!!!"

9 / 10
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43 Report
  • Anonymous
  • February 5, 2012

"I have been on various medications for years, some have been Lortab, non-narcotic pain medications, MS Contin, OxyContin, and fentanyl patches. I was on 150 micrograms of fentanyl every 48 hours before switching to Opana ER. Initially, I was taking 20 mg of Opana twice a day, and it was not sufficient for my pain, but I couldn't handle the side effects of the fentanyl patches (narcolepsy), so I worked with my doctor to increase my dosage and frequency, so that I now take 30 mg twice a day and 20 mg once a day. It is expensive, but I am finally able to live a near-normal life. I play with my kids, I don't miss work, and I even keep the house up (with great help from my better half). Opana ER has been great for pain relief with almost no side effects!"

10 / 10
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61 Report
  • muc...
  • July 20, 2010

"The doctor had me on 100 mg of morphine ER 2x a day, the side effects were really bad. He put me on Opana ER 40 mg 2x a day and Opana IR 5 mg for breakthrough pain. It's the best pain medication I've ever been on. I have spinal stenosis, degenerative disc disease, and osteoarthritis. I was in terrible pain before Opana, now at least I can stand to be alive again."

8 / 10
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63 Report
  • Lor...
  • August 7, 2015

"Been taking Opana for 15 months now and couldn't be happier. Diagnosed with DDD in my L-4, L-5, S-1, scoliosis, and fibromyalgia 3 years ago. My PM doctor put me on MS Contin 60 mg 2x a day, which I had an allergic reaction to… My feet and legs swelled up. He then put me on a fentanyl patch 75 mcg, which my body did not tolerate, I ended up getting pains down my neck and severe nausea. A guy ran a red light and T-boned my side of the car. In the hospital, they gave me dilaudid for pain, which completely took my pain away. My doctor decided at that point to put me on EXALGO 12.5 mg 1x a day. Worked better than anything! Insurance stopped covering it, GAHH. Put me on Opana ER 20 2x a day and IR 3x a day. Amazing! No side effects!!!"

10 / 10
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44 Report
  • Goo...
  • November 14, 2009

"Currently taking 2 x 10 mg ER and up to 4 x 5 mg IR. Tolerance has developed quickly, what used to take the pain away only halfway dulls it now. My doctor is not convinced of my pain. I have asked for more, but he, without coming right out and saying no, has refused me an increased dosage. My advice is, even though Opana works well initially, you will develop tolerance rapidly and require more in order to provide pain relief. I do have several bulging discs, but for some reason, my doctor does not see this as cause to increase the dose—only continue the same dose that I began with about 9 months ago. Sorry for the rant, but it may be something you might not have considered if I had not brought it up. From what I have gathered from independent research on Opana and Oxycodone, Opana has the greatest tolerance increase potential between the two."

7 / 10
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63 Report
  • Two...
  • Taken for less than 1 month
  • November 11, 2012

"I took one dose of 20 mg of Opana ER. I became dizzy, woozy, lightheaded. I developed a pounding headache! I became extremely agitated and anxious. I became very shaky. My lower back pain increased, not decreased. Seven hours after taking this one dose, I had projectile vomiting."

1 / 10
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52 Report
  • pop...
  • January 31, 2012

"I have neck and back pain requiring fusion surgery, already had two laser procedures on them. Only thing I haven't taken is fentanyl. Started with a morphine Avinza, Dilaudid combination, to Dilaudid and oxycodone combination to straight up 8 x 30 mg Roxicodone and Xanax daily. Pain relief with that was amazing and cheap. However, with that being said, I asked my doctor about switching. Since I was on such strong medicines, I was able to get 2 x 20 mg Opana ER daily along with 5 Opana IR. Have been on this four months now, and it's the best relief I have had in five years."

9 / 10
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52 Report
  • len...
  • December 30, 2007

"The doctor's instructions were to take 1-2 or 3 tablets at bedtime for cervical pain. I tried 3 on 3 different evenings and, unfortunately, had absolutely no pain relief. I also tried for pain in my hip and thigh with no results. (I do have a very high pain threshold and, consequentially, need strong pain meds). Haven't yet found a drug for pain relief at night."

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  • You...
  • September 12, 2009

"Opana has worked better than anything I have been prescribed. I have several bulging discs, 4 in the lower back and 4 mid back. I was taking 3000 milligrams of Vicodin daily, 8 to 10 x 325 mg tabs. Now, I take 2, 20 milligram Opana daily, and only 2 or 3 Vicodin as needed. Be sure to take Opana on an empty stomach, and don't eat for about 2 hours. Opana is incredible, my next doctor's visit, I will request a slightly higher dose and quit the Vicodin altogether. Thank you, Opana!"

8 / 10
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57 Report
  • Anonymous
  • April 22, 2009

"I have lupus, arthritis, and had most of my back crushed in an auto accident. Opana is the only pain medication that has relieved a majority of my pain throughout the day. I take 40 mg every 8 hours, and I am able to walk around and do things I couldn't do before when I was on the patches and all the other drugs I tried. Opana is the best long-term medication that keeps working without fail for me."

9 / 10
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58 Report
Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.