Osimertinib and Rash: What Users Say

• LAF...
• Taken for 1 to 6 months
• June 9, 2024

Osimertinib for Non Small Cell Lung Cancer "I was diagnosed with stage 4 Adenocarcinoma non-small lung cancer end of October 2023. Had bloodwork and discovered I had EGFR mutation. My oncologist told me of this targeted therapy just taking a pill daily. It's Tagrisso. I was scheduled for chemo but turned out I thank God didn't have it. Started on Tagrisso 80 mg, was on it for 2 months and got a severe skin rash. My doctor took me off for a month until the rash cleared up, then started me back on but half the dose. So far just a couple of spots have developed on each leg and one under my left breast. I put the gel on daily that my oncologist prescribed. That's the only side effect so far that was serious. Been on it now for 5 months, recent scans showed my tumors have shrunk considerably, the large one in a lymph node outside the lung in the chest cavity is now half the size and the small ones gone, and my oncologist said the disease is now minimal and small and I'm doing amazingly well. Tagrisso is a magic pill!"

• Alv...
• Taken for 1 to 6 months
• September 29, 2017

For Non Small Cell Lung Cancer "I developed resistance to erlotinib, which served me well for three years. I now have 4 months with Tagrisso (osimertinib), and I feel much better, the side effects of diarrhea and rash are more tolerable and showed improvement to the RX."

• Rac...
• Taken for 6 months to 1 year
• March 2, 2025

Osimertinib for Non Small Cell Lung Cancer "I have non-small cell lung cancer metastasized to bones and liver. I was diagnosed in last July 2024. I started Tagrisso in August and also had 4 courses of carboplatin and pemetrexed, then two more courses of just pemetrexed. I had a facial rash for the first few weeks on Tagrisso and then smaller intermittent rashes on my arms for a few more weeks. After that, I developed worsening constipation (chronic constipation has been a lifelong problem for me), a frequent feeling of pressure in my lower intestine, and very achy muscles. My dosage was reduced to 40 mg and the muscle aches improved, but not my intestines. In my seventh month, I started getting an intermittent queasy stomach. My scans have been good-initially showing a 60% reduction in tumors, then stable to slight shrinkage. My appetite has continued to be good, but I have still lost some weight, which concerns me. I do also have fatigue and spacey feelings that come and go."