Ondansetron for Nausea/Vomiting User Reviews

• zof...
• Taken for 2 to 5 years
• December 18, 2019

Zofran (ondansetron) "I have been taking this medication at least once a week for about four years now. I have terrible stomach issues now that I no longer have my gallbladder that cause stomach pain, nausea and no appetite, as well as anxiety that manifests as nausea and stomach pain. I also have a HUGE fear of vomiting. This pill has always worked and kept me from vomiting, but on occasion the nausea sticks around but it’s nothing too terrible. I don’t know what I would do without this medication. It helps me live a normal life. I take 4 mg every 4-6 hours as needed, if it’s a rough day I’ll take 8 mg every 6-8 hours. The only downfall is the side effect of constipation, but as someone who is terrified of vomiting, I’ll take the constipation over vomiting any day."

• Ste...
• Taken for 2 to 5 years
• October 28, 2019

Zofran (ondansetron) "I take oxycodone for chronic persistent back pain because of spinal stenosis. As a result, I frequently have nausea and vomiting, roughly 4-5 times a week. My pain management doctor always prescribes Zofran which doesn’t help in the slightest. I tell him this, but he keeps prescribing it nonetheless. He says it is safe and doesn’t make you sleepy. I say if it doesn’t work, what good is it? My GI doctor gave me Phenergan, which does help, but he tells me to go back to the pain guy to get more. I go back, tell him, yet he just gives me more Zofran. DON'T YOU JUST LOVE PHYSICIANS WHO LISTEN TO THEIR PATIENTS (sarcasm)."

• cam...
• August 7, 2014

Zofran (ondansetron) "I have generalized anxiety disorder and suffer from emetophobia. The anxiety causes stomach upset, and the fear of throwing up increases the anxiety in a vicious cycle. My psychiatrist prescribed Zofran while I was trying out SSRIs to help me get through the first few weeks of side effects. I am now on Celexa with a lot less anxiety and only take Zofran as needed! It works great, it just makes me feel sleepy. Haven't run into any constipation yet."

• Pic...
• Taken for 1 to 2 years
• April 20, 2021

Zofran ODT (ondansetron) "This medication makes me more nauseous than before taking it. After 3 surgeries and multiple nausea-filled days due to a chronic health condition, I've concluded that this drug makes things worse for me. I kept hoping it was all in my head, but other anti-nausea meds (and even peppermint) work almost immediately, at least to a certain extent. Whereas this always makes me 10x worse to the point of vomiting. It also gives me really bad headaches, and I don't ever get headaches in general. It's the only medication that gives me this side effect. So I think this either works very well for people or makes it worse. I'm wondering if it has to do with brain chemistry since it's a serotonin blocker? I'm severely ADHD with mild OCD and depression. Perhaps certain brain wiring just doesn't benefit. I'd love more research to be done on this since it's the standard anti-nausea treatment given in hospitals."

• Mel...
• Taken for less than 1 month
• January 5, 2020

Zofran (ondansetron) "I've taken this medication on various occasions, and honestly, it's a lifesaver. Today, I woke up with a stomach bug. I got out of bed, drank a glass of water, and not even five minutes later, I was bent over the toilet. I laid down, and maybe half an hour later, again within two hours, I had taken six horrible, dry heaving, painful, and exhausting visits to the bathroom. Finally, I rushed to the doctor, where it happened one more time before being seen. She quickly gave me one of these, and I haven't thrown up or felt nauseous since. I've been able to keep down liquids and solids with ease. I see this medication as a great tool to help me get better faster than expected!"

• Dol...
• Taken for less than 1 month
• June 5, 2020

Zofran (ondansetron) "I have acute gastritis, and this medicine makes me feel worse. Too many side effects are associated with it. I feel more pain in my stomach, lightheaded, dizzy, and just overall bad. I was starting to feel better before I took this medicine, and now I have to wait for it to run its course."

• Man...
• Taken for less than 1 month
• September 26, 2014

Zofran (ondansetron) "I had the norovirus last year and took Zofran, and it worked very well. The pills are small and dissolve easily on your tongue, so you don't have to drink water and risk throwing up the medicine. If possible, I think it would be great to offer this medication over the counter."

• Anonymous
• Taken for less than 1 month
• April 20, 2013

Zofran ODT (ondansetron) "I've been taking ondansetron ODT 8mg tablets for about 2 days due to nausea caused by a kidney infection. When I take the tablet, it doesn't help and makes me more nauseous than I was before. I just took it half an hour ago to be sure, and I immediately became more nauseous. So I'm pretty sure it just doesn't work for me, and I'm wondering if anyone else has this problem?"

• Hgg...
• April 22, 2021

Zofran (ondansetron) "I have hyperemesis gravidarum (HG) and have been miserable. Zofran is keeping me out of the ER right now. At first, I noticed it made me a little dizzy, and it still makes me feel just a little weird within the first hour, but it’s extremely tolerable. The constipation is super annoying, but talk to your doctor about it if that’s an issue, and you can probably take something to help that. It stops me from throwing up, but I am still definitely nauseous. Brings it from like a 10 to a 5 or 6 maybe, but I can EAT now. That is huge. I am eating small meals when I haven’t had a meal in weeks. I’ve been barely eating and drinking. I am completely dependent on Zofran to be any type of functional right now. It makes me a little tired but also gives me more energy to not just stay in bed all day because it makes me feel better. Highly recommend, just watch out for the side effects I mentioned. Nothing to be scared of, extremely tolerable for me :)"

• Vha...
• Taken for less than 1 month
• December 23, 2019

Zofran (ondansetron) "Day 1 of what the docs think is the flu, first time puking in a long time. Couldn't hold down water or Pepto. Was so nauseous I was having dreams that were making it worse. Zofran has kicked my nausea, and now I can eat and drink again and therefore take ibuprofen and my flu meds. Holy cheese, Batman."

• KPP...
• Taken for 10 years or more
• January 4, 2020

Zofran (ondansetron) "I’ve had a fear of vomiting for years (25+). Found out about this medication when my best friend had hyperemesis while pregnant, and it helped her stop vomiting. I asked my doctor if I could get it because I had such horrible anxiety about throwing up. I take Zofran 4-8 mg when I have bad nausea and anxiety, and it seems to help me. I did throw up once after taking it, but I think it was because I had worked myself up so much!"

• Anonymous
• September 15, 2011

Zofran (ondansetron) "I suffer from both severe emetophobia (fear of vomiting) AND a panic disorder which causes nausea and gastric upset. I spent many years trapped in a horrible cycle of panicking any time I felt the slightest twinge of nausea, which in turn induced intense stomach upset, sometimes to the point of heaving. I've tried other anti-nausea medications in the past (Phenergan, Compazine), with so-so results, and the annoying side effect of extreme drowsiness. Zofran has been a real lifesaver for me. Within minutes of taking a pill, my nausea subsides. The only side effect I've experienced has been constipation, but I'll take that over vomiting any day!"

• pre...
• Taken for less than 1 month
• March 2, 2015

Zofran (ondansetron) "I'm taking this for morning sickness. I feel like it has given me my life back. I lost over 6 lbs in 5 days due to nausea and vomiting and was too sick to do anything for my toddler, myself, or my home. I can tell when it's starting to wear off (at about 6.5-7 hr.) because the nausea comes right back. I'll take being backed up and a little drowsy as a side effect... It allows me to eat and keep things down and be present in my family's life. Never thought I'd be so happy to take a medication, but I'm SO thankful for Zofran."

• Xti...
• March 9, 2015

Zofran (ondansetron) "The only medication that really does the trick. I have been prescribed it twice now due to a severe stomach virus, and it gave me relief after 20 minutes! I didn't throw up anymore afterwards, and it helped me sleep after a very restless night. Love it!"

• Bet...
• Taken for 6 months to 1 year
• June 27, 2016

Zofran (ondansetron) "I have Crohn's disease, emetophobia, and I also take quite a few pain meds for chronic pain, all of which make me extremely nauseous, so I suffer nausea a lot! Ondansetron is a lifesaver for me. I take 4 mg every 8-12 hours, and on a good day, some days I take 8 mg if it's really bad! I've been taking it daily for nearly 6 months, and it is still as effective as the first time I took it! I live in the UK, so I am fortunate that I don't have to pay eye-watering prices. I'd recommend it to anybody, it's brilliant."

• qh3...
• Taken for less than 1 month
• May 21, 2015

Zofran (ondansetron) "I was extremely hungover and was vomiting for about 14 hours non-stop before being prescribed Zofran. I know it seems silly to get medication for a hangover, but I was becoming dangerously dehydrated from binge drinking and heavy vomiting, as I was unable to keep even a sip of water down. Not even ten minutes after taking the medicine (dissolvable pills), I already felt significant relief from the nausea, and therefore the vomiting as well. A bit expensive, but completely worth it."

• pan...
• Taken for less than 1 month
• February 8, 2015

Zofran (ondansetron) "Last night I had severe diarrhea and stomach pain and dizziness, maybe I was dehydrated from the stomach bug, so I went to the ER and they said they were going to give me Zofran, which I have a phobia of trying new pills, but my stomach hurt so bad. I told the nurse I'd break it in half till I seen how small it was, and she said just let it dissolve on your tongue, so I did, and it had a strawberry flavor, which I told her, 'Wow, this tastes good.' Within about 5 minutes, my nausea had gotten so much better, it even relaxed me a bit. I'm telling you folks, if you have the stomach bug or stomach aches, give this a shot. I had no side effects at all, maybe a little sleepiness, but like others, I'll take that over the stomach pain. Thanks, Zofran."

• Art...
• October 23, 2014

Zofran ODT (ondansetron) "Zofran completely changed my life! The ODTs are perfect because I suffer from anxiety, and sometimes it gets so bad that I begin to vomit. Also, with Irritable Bowel Syndrome, it helps control the nausea and vomiting associated with it. I get no side effects, but my insurance doesn't cover more than 5 tabs at a time, so I have to get it in regular pill form sometimes at Costco, where they have the cheapest price."

• Jor...
• Taken for 1 to 6 months
• July 19, 2024

Zofran (ondansetron) "Was diagnosed with cannabis hyperemesis about 2 months back. Unfortunately, at the time, it didn't seem like anything was going to work. Eventually, was admitted to the hospital due to severe dehydration. Body went into survival mode. Was throwing up for hours a day until dry heaving. About a month after symptoms started occurring again. Was given promethazine (which works great but sedation is tenfold) as well as it can only be taken for about 10 days at a time due to its harsh nature on the body. Started taking Zofran again, this time around it works. Knocks down the nausea from a 10 down to a 5 or 6 on good days. It really does help. I don't have any major side effects, aside from the constipation. No tiredness or dizzy spells. The activation time is about 30-60 minutes for me. Usually 4 mg every 8 hours. If that doesn't help, Benadryl 25mg 3x daily on top of it can also help with nausea."

• mik...
• Taken for less than 1 month
• September 13, 2016

Zofran (ondansetron) "This medicine potentially saved my life! I had no appetite. In three days, I lost 7 pounds! My wife took me to the ER, tests were ran, and the physician prescribed Zofran 4 mg, and it worked. Within ten minutes, I was eating a turkey burger with garlic oven fries. My anxiety is gone as well. I would recommend this medicine to my friends and family."

• Jas...
• Taken for 10 years or more
• May 12, 2021

Zofran (ondansetron) "I take Zofran only if I feel nauseated with migraine headaches. Otherwise, I take Phenergan for nausea related to severe pain. These two work very differently but work very well for my specific needs. I can't take Phenergan for migraine nausea, it doesn't work. Only Zofran works for migraine nausea. I do often have to take two, though."

• J13...
• Taken for less than 1 month
• December 16, 2016

Zofran (ondansetron) "I was given this medication after a severe bout of anxiety and panic attacks. I lost 25 lbs in 2 weeks due to the panic and had no appetite. Of course, when you don't eat for that long, nausea can easily set in. I couldn't even move off the couch for fear of feeling extremely sick or dry heaving. I was finally given this miracle pill, and the nausea quickly went from 10 (the worst) to easily a 2 or 3 within about 45 minutes. I took it for a week as I tried to get my appetite back and anxiety under control with other meds. Highly effective. I did experience some constipation from this medication, but that could also be due to the starvation mode I was in for 2 weeks. Either way, highly recommend to anyone dealing with nausea."

• ash...
• November 10, 2013

Zofran (ondansetron) "As this viral stomach bug tore through me and all my kids, it presented excruciating stomach pains. I was prescribed Zofran for myself after puking and going diarrhea for 8 hours back to back with no relief. It worked like a miracle. As this bug started on each kid, I let them puke 6 times to get the virus out. Once they were consistently dry heaving, I gave one tablet (4 mg), which is recommended for 2 to 12-year-olds. Thank God it allowed the stomach contractions to subside, and they fell asleep! However, would not use on kids 4 and under without consulting an MD."

• Ita...
• Taken for less than 1 month
• December 9, 2016

Zofran (ondansetron) "I've had central vertigo for years, but the nausea and vomiting have increased lately. My gastroenterologist prescribed Zofran 4 mg once a day. It's a miracle! I can go out and shop without vomiting in the aisles of the grocery store. I have my life back."

• Ess...
• Taken for 1 to 6 months
• January 7, 2015

Zofran (ondansetron) "I am currently 25 weeks pregnant and have had bad nausea/morning sickness since week 5. This medicine has been wonderful. There are times when I still feel sick, but it's bearable, and I don't throw up. I've been taking it so long now that the sleepiness it causes doesn't affect me anymore. However, the constipation from it has been a downer."