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Zyprexa for Bipolar Disorder User Reviews (Page 4)

Zyprexa has an average rating of 6.3 out of 10 from a total of 159 reviews for the treatment of Bipolar Disorder. 53% of reviewers reported a positive experience, while 26% reported a negative experience.

Reviews for Zyprexa

  • sj1...
  • Taken for less than 1 month
  • December 30, 2019

"I had a horrible, 6-day experience with this medication Zyprexa. While it was prescribed to me primarily for sleep, which 5 mg was effective, it made my anxiety 10x worse with paranoia and tremors. It was the worst. It has been three nights without it now and I still feel it's effects of increased anxiety and a fog-like head. The physical symptoms ceased 48 hours post-Zyprexa. I took 20 mg of Paxil with this medication for anxiety and was noticing some improvement with Paxil alone. Zyprexa made me feel as if I was never taking Paxil AND take five steps backwards. My official diagnosis is TBD but this was the first medication I've taken where I absolutely refuse to take again at any dosage"

1 / 10
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  • Anonymous
  • July 14, 2009

"At first, I was reluctant to take this medication, but eventually, I realized that I needed it. This medication helps me sleep longer, fall asleep faster, and wake up less. Also, this drug has given me very few side effects, which are insignificant."

9 / 10
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40 Report
  • Dim...
  • May 5, 2018

"Out of the 4 antipsychotics I tried, this one worked wonders for me. I was diagnosed back in 2011 for a psychotic episode and developed bipolar psychosis. Took 5 mg for years, and I was feeling great. The only thing is that I would have some tactile hallucinations but wouldn’t hear any voices. I would just feel like a crazy maniac who wouldn’t sleep for days before going on Zyprexa. Anyway, I went off of it, and then a year later I am here taking it again because I just can’t stand my anxiety, delusions, and mood swings. I mix it with Seroquel sometimes. Anyway, this drug works wonders. I don’t get an increased appetite. The only problem is that when I wake up, I don’t feel like eating anything, so I end up eating at 2 PM. The side effects for me are decreased appetite and some fatigue, but other than that, I can finally enjoy life again. Remember that it takes a few weeks for it to take full effects, and side effects do become more tolerable over time."

9 / 10
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21 Report

Frequently asked questions

  • mee...
  • Taken for 1 to 6 months
  • November 12, 2015

"I have been taking Zyprexa 5 grams a day, and I don't get any effects from the pill. It keeps me mellow but not tired like everyone says. Kinda helps with mood swings, but not really! At least not for me."

4 / 10
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  • Jad...
  • Taken for 1 to 6 months
  • December 26, 2014

"This medicine works really well as a mood stabilizer for me. The only major drawback is weight gain. I just can't control myself when the carb cravings happen. I am usually very much in control of my dietary habits, but on Zyprexa that just isn't possible. I also suffer from schizoaffective disorder and hear voices. Although Zyprexa suppresses them, it does not completely get rid of them in my case; they are quiet enough to tolerate, though. I have gained 35 pounds in less than about a month and a half. I am going to wean off of these and ask the psych-doc for something else."

7 / 10
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28 Report

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  • Tkv...
  • Taken for 1 to 6 months
  • September 27, 2015

"This drug caused me a lot of problems. At first, it made my mania go away, but after a month on it, I developed very stiff muscles. I was given Cogentin, but that didn't help, and after two months, I became very spaced out, and my family said I was saying some weird stuff, but I couldn't remember. My pdoc finally took me off Zyprexa after four months when I showed her how stiff my muscles had become (walking a block was a chore) and told her my leg would start twitching by itself. Overall, a horrible experience."

2 / 10
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  • Ter...
  • Taken for 5 to 10 years
  • October 11, 2019

"Started Zyprexa 7 years ago. I had never been happier. I laughed, enjoyed life, lost the paranoia - then my yearly physicals started showing my A1C was elevated, so I started on Metformin. I gained between 6-12 lbs/year (132-179). Now on a BP med. Suffer from dry mouth & tongue edema. I take 25 mg Benadryl every 4-6 hrs to prevent it. I've weaned down to 1/2 of 1.25 mg every 3rd night. I'm okay as long as I don't go past that 3rd night. If I try for 4, I pay dearly. It's like I've been hit by a Mack truck - the worst case of flu ever. I take the missed dose & 24-36 hrs later, I feel human again. This drug saved my life because I was suicidal, but also now I don't want to die of complications from the co-morbidities that I'm developing now because I can't get off it. The real kicker: Zyprexa affects your metabolism, so it's even harder to lose weight, and it interferes with how Metformin works, making it less effective. Talk about a double-edged sword. I may be on this for the rest of my life."

8 / 10
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  • Anonymous
  • November 7, 2012

"After the first time I took Zyprexa, my head and legs felt like they weighed one ton each! I tried it for 2 weeks, and this got worse! It increased my appetite a lot too. My doctor is currently trying to find a medicine that works for me. It's so hard as I get a lot of strange side effects on these medicines!"

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  • Ed ...
  • Taken for 5 to 10 years
  • November 26, 2016

"I took 3 mgs of Zyprexa, contained in Symbyax, nightly for about 6 years. The medicine worked well for the first 2 to 3 years. Around year four, I started having severe side effects and did not realize it was from the Zyprexa as it had been working so well. I suffered with increasing seizures for about three more years. Bad ones. I wound up in the hospital emergency room, and it was the ER doctor that informed me that the Zyprexa was causing the problem. My regular doctor denied Zyprexa as a contributing factor to my seizures. I quit the Zyprexa cold turkey. To say the least, it was an absolutely horrible experience. Wean off this drug over a long period of time, and even then, get ready for horrendous withdrawal symptoms after your last dose."

3 / 10
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  • Jas...
  • Taken for 5 to 10 years
  • June 27, 2018

"DO NOT take this medication unless you are either psychotic, bipolar or have an extreme neurological condition. I took this medication for 8 years and it ruined my life to be honest. These drugs are EXTREMELY dangerous and powerful and can ruin your life even by taking it for 1 week. This drug is NOT for anxiety or ANY mild to average condition. Move to the countryside for 3 months and rent a cabin, it will solve your issues. If you are a parent, do not EVER put any child on this drug. Anti-psych drugs are 1000 times more dangerous than you can ever imagine. Same goes for Abilify or any atypical or typical anti-psychotic. Tardive dyskinesia is a potentially permanent side effect that can ruin your life within a week. Saying that, they work EXTREMELY effectively for severe mental disorders and may save your life if you are suicidal."

5 / 10
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  • Hon...
  • Taken for 1 to 2 years
  • February 13, 2018

"Been on 20 mg a day for a couple of years. Been off of everything for about eight months. When I was taking it, I had zero issues with weight gain. Another huge benefit was that it reliably put me to sleep. Take my 20 mg football in the evening, and it’s lights out within two hours. But getting up in the morning was tough. Plus, it did slow me down mentally. I didn’t think it did, but I had a few old friends point out that I’m way slower than I used to be. Like most psych meds, it can work wonders for one patient and do more harm than good for another. Due to life’s circumstances, I had to quit cold turkey. Bad idea. Sleepless nights and all that... Thankfully, my condition is on a very mild end of the spectrum. You absolutely have to work with your doctor to find out what works best for YOU! All the best!"

10 / 10
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  • Ron...
  • Taken for 1 to 2 years
  • October 21, 2022

"I've been battling depression and bipolar disorder for over 25 years. Tried everything under the sun and nothing really made me feel like a normal person until olanzapine. I started a year ago and was on 2.5 milligrams for 6 months and then bumped it up to 5 milligrams currently. The only drawback is weight gain (15 lbs) but I'm feeling well enough to start exercising and should get back to a healthy weight soon. This medication is a life saver."

9 / 10
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  • Anonymous
  • March 2, 2008

"My 6-year-old son was diagnosed with bipolar disorder. I thought it was ADHD, but they started him on Zyprexa, and we've seen a lot of improvement in his behavior. Would highly recommend. Virtually no side effects. He eats a little more, but most 6-year-old hyperactive boys could stand to eat a little more."

9 / 10
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  • Anonymous
  • December 9, 2009

"I've been taking Zyprexa for almost 3 years now. It has been wonderful for me and my family. I had tried so many different medicines that I had given up. I now hardly have any mood swings, and I can sleep at night. The downside is that I have gained a lot of weight, but to make me easy to live with for my family, it's worth it!"

10 / 10
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  • TJa...
  • Taken for 1 to 2 years
  • July 7, 2018

"Works great every time! I have rapid cycling bipolar, and this is the most effective out of all antipsychotics. Sometimes they put me off it, but every time I’m on it, it feels like a world of change, like my brain starts to function again."

9 / 10
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  • MT2...
  • Taken for 6 months to 1 year
  • April 7, 2017

"I was diagnosed with psychotic depression for 7 months, and my psychiatrist put me on Zyprexa 5 mg. After using antidepressants, I got into mania. This medicine is a miracle. I was relieved in one week. I am still taking it, but I became a bit hesitant to continue due to some horrible reviews. Tried Invega and had suicidal thoughts. This medicine is great for mood in combination with Lamictal."

8 / 10
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  • Bet...
  • Taken for 1 to 6 months
  • April 25, 2018

"My psychiatrist put me on 10 mg of Zyprexa and 20 mg of Prozac. He said those two meds are supposed to work well together. After two months, I was still feeling depressed, so he increased the Zyprexa to 15 mg. This has been a miracle drug for me. I fall asleep within 30 minutes of taking it and sleep very well, except it is difficult to wake up in the morning. I set three alarms around my bedroom. One I have to physically get out of bed to turn off, so it helps me get up. But that side effect is getting better after two months of taking Zyprexa. I no longer have ruminating thoughts or bouts of rage. My mood is very even. I have had some weight gain due to the med making me feel hungry all the time. Now I'm trying to drink water instead of eating, and that seems to help."

9 / 10
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  • Yay...
  • December 6, 2016

"I had been so unwell off meds for over a year and vomiting daily due to bipolar. I thought vomiting was from physical illness. As soon as I started this med, all BP symptoms left, and my stomach is settled. No sexual side effects. Old me is back. No sides! Miracle drug! Weight gain for me will be a plus, not negative."

10 / 10
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  • Anonymous
  • September 30, 2011

"I have been taking Zyprexa for about three years. Although it seems to help me restrain from the hyper-manic episodes, it seems to also hinder my personality. I feel like my spirit is being suppressed, and life for me is not as enjoyable. I do, however, feel it makes it easier for my loved ones, as I don't send them through my 'energetic' episodes that they say are more tiring for them. I, too, have gained a lot of extra weight, especially around the middle. I feel starved an hour after eating."

6 / 10
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  • Gon...
  • Taken for less than 1 month
  • April 22, 2017

"I gained 10 lbs in under 1 week, which sets a speed record among the weight-gain meds I've taken. Since that pushed me up to the pre-diabetic border, my psychiatrist pulled me off of it ASAP - not to mention that when you're severely depressed, how is super chunking up supposed to make you feel better no matter how well the med works? 1 month & I would have been up 40 lbs! I felt no other side effects, nor any positive effects, but 1 week probably wasn't long enough for it to make a difference in my mood - only my rear end."

1 / 10
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  • daB...
  • Taken for 6 months to 1 year
  • April 8, 2024

"Zyprexa has been an amazing drug. I have bipolar and psychosis, and it has worked miracles for my mental health. I have left what I thought was a mothership and have a good life here on earth. Seriously, it's a great drug and sometimes you need that little bit of help."

9 / 10
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  • Anonymous
  • March 15, 2011

"I have been on Zyprexa for 6 months now, and it has calmed me down quite a bit. I have no more racing thoughts. I don't hear voices or see things anymore. The only downfall to this medicine is the weight gain. I would highly recommend it though."

8 / 10
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  • pre...
  • March 7, 2010

"I have been diagnosed with bipolar for 15 years and for the first time experienced a manic state beyond anything I imagined or experienced before. I was suffering from severe paranoia and psychosomatic symptoms. Zyprexa is a Godsend, and I am happy with it. My major problem with it is the morning hangovers I feel. I have gained weight, but desperately needed to do so."

8 / 10
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  • edy...
  • June 30, 2010

"I was diagnosed with bipolar disorder at the age of 49. I was immediately put on Zyprexa and, essentially, the next four years are a blur to me. To say I felt like a zombie is a gross understatement. I changed my doctor and insisted he take me off the drug, which he did. I am now taking 'plain old lithium' and have been doing well for the past five years. I understand that everyone doesn't have the same experience with Zyprexa that I had, but people should be aware that there are long-proven alternatives. I only wish that my doctor had considered them first."

1 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • September 21, 2012

"Puerperal psychosis: Made me incredibly hungry and then not even remember eating things! One time I ate seven doughnuts in one night - I only know this because I found the empty packet the next morning. I have no memory of eating them. I put a lot of weight on doing this."

4 / 10
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25 Report
Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

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