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Olanzapine for Depression User Reviews (Page 3)

Brand names: Zyprexa, Zyprexa Zydis, Zyprexa Relprevv, Zyprexa Intramuscular

Olanzapine has an average rating of 4.9 out of 10 from a total of 163 reviews for the treatment of Depression. 36% of reviewers reported a positive experience, while 46% reported a negative experience.

Reviews for Olanzapine

  • Anonymous
  • September 27, 2020

"Had a very bad effect with olanzapine with had hair loss. I don't know if anyone had this effect but for me it was really bad. I trying to stop on olanzapine now, waiting for the dr to prescribe something else. I had weight gain too. I wish I can continue with it but unfortunately has to stop. Had anyone experience hair fall please advise."

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  • Maxie...
  • December 23, 2016

Zyprexa (olanzapine) "Definitely relieved morning anxiety attacks. I'm also taking Effexor and Klonopin. I take the Zyprexa at night because it does make me sleepy. I wasn't eating anything at all before starting this drug, so I'm not worried yet about the weight gain; I'm not overdoing it with the food. I don't plan to be on this for long; my doctor told me it's not really a maintenance medication. But if it gets me through the Holidays and my horrible anxiety about work, I'm fine with that."

7 / 10
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45 Report
  • Chook
  • July 20, 2015

Zyprexa (olanzapine) "This medication has made me unemotional and boring and like many others I'm forever hungry. I have put on an insane amount of weight, admittedly needed, due to suffering anorexia, but when I started on this medication I weighed 37kg and 6 months later nearly doubled to 65 kg. This I feel is an unnatural weight gain in such a short time, and now I don't go out due to feeling bad about how I look."

1 / 10
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50 Report
  • Hazyh...
  • Taken for less than 1 month
  • January 4, 2022

Zyprexa (olanzapine) "After being prescribed zyprexa for depression I immediately went to Google for reviews, they were horrible!!! In all honesty it works for me yet I'm on a small dose of 5mg at bedtime. I can tell a huge difference in my mood. I can't speak for anyone else but I hope to continue taking zyprexa until hopefully I no longer need it."

10 / 10
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19 Report
  • Mom...
  • October 28, 2010

Zyprexa (olanzapine) "My doctor started me on 5mg of Zyprexa and the first 2 days I slept over 14 hours falling asleep within 20 mins of taking it. By day three I couldn't sleep at all and went on for days making me feel out of control, confused, forgetful, pretty much out of it and unable to even have my daughter home with me. I was also very bloated, feeling and looking. On the start of the 7th pill/day I began swelling to the point of GOUT, had breathing problems, dry mouth, was oddly emotional/ crying a lot, and hurting badly due to the MASSIVE swelling and couldn't put on any of my pants. I quit taking the medicine but the next night it all got worse with the addition of tightening in my chest. I am now having skin irritations on my hands. This medicine is bad news."

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  • Now...
  • August 6, 2021

Zyprexa (olanzapine) "I have never written a review but what I am experiencing is something I do not wish on anyone. Please listen to what I am saying before it is too late for you. The first thing I want to point out is that they say this drug is not addictive. I will tell you that is the biggest crock I have ever heard. It is beyond addicting. You cannot just stop it. The nausea, vomiting, upset stomach, depression, mania, insomnia, desire to just die to get this over with, shaking, you feel cold and hot at the same time. The withdrawals are unbearable so naturally people keep taking it. The only solution I see to this is to find a rehab for this and have professionals help me through this. I should have never been placed on this drug to begin with. I needed to gain weight. But to give me one of the strongest antipsychotic for that is criminal. Sure I gained 40 pounds but I have no life. No desire to live. No focus. No motivation. Nothing. If you are not psychotic do not take this poison."

1 / 10
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  • y-thi...
  • Taken for 6 months to 1 year
  • May 12, 2016

"This med is the only thing I tried that worked for my anxiety and depression. It might just be the way my brain is made, but every other antidepressant I tried made me worse or caused reactions. Anti-psychotics however help me. I've been taking olanzapine for a year and haven't noticed much side effect, no weight gain at all. It doesn't completely cure my depression, but I feel much better. Dr. suggested that I take a higher dose, but I'm a bit worried about diabetes."

9 / 10
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  • neil...
  • August 29, 2016

"I'm 47 and have had classic depression and anxiety since my early 20's. Been on citalopram, fluoxetine, marititizapam and now sertraline. Also have dizapam as a back up. This year has been extremely difficult no major incidents but my depression was changing from day to day. No ups but plenty of downs. Finally couldnt cope and pressured the dr to give me something for mood swings in addition to my sertraline. I can say I have felt the best I ever had in 20 years!!!! My mood before was a 4/10 and now its a 7/10 which is great for me. I even seem to get excited about life which I havent done for years. It does make me hungry but I dont care as this so far is a life saver. Also gives me a very dry mouth so need lots of water."

10 / 10
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  • Anony...
  • October 29, 2011

Zyprexa (olanzapine) "After taking the 2.5 dosage for 4 days I feel very irritable. I am experiencing crying spells, tiredness, extreme moodiness and just want to be alone. This medicine was prescribed for a mood disorder that I have been experiencing. I also take other anti-depressants. I don't think this is a good mix with other medicines or just not right for me."

1 / 10
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  • Gemma...
  • January 4, 2023

Zyprexa (olanzapine) "If you want to lose your good emotions and connections to the world, then take this poison. I'm not sure why you would want that though. You'll get obese on this crud, horrible torturous withdrawals that will last years. Who in their right mind would invent something like this? Only a psychopath."

1 / 10
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12 Report
  • Color...
  • Taken for 2 to 5 years
  • January 24, 2016

"This drug did horrible damaged my life! When I went on this medication, no one told me I would gain 60 pounds in a matter of months! I would have never gone on it. Even after getting off the drug I could not loose that weight. Fortunately, after 10 years, a doctor suggested testosterone therapy in hopes it would take the weight off. It was a miracle! I lost about 45 lbs. BUT I also lost 10 years of my life. Now I have permanent damage to my skin. Excess skin on my face and body after I lost the weight. The doctors tell me it won't return to its original state because I gained the weight so fast. I was a zombie while on the drug. Don't let your loved ones take it! I want to cry when I look in the mirror at my body now!"

1 / 10
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41 Report
  • zuser
  • April 26, 2019

"I have been taking HALF of a 2.5mg dose for a few months. It makes me so exhausted I can barely think straight. It does help with anxiety but only so much in that it puts me into a complete state of exhaustion. I feel mentally and physically depleted. The level of drowsiness/impairment concerns me at what is probably considered a sub-therapeutic dose."

2 / 10
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28 Report
  • piceli
  • Taken for 5 to 10 years
  • November 5, 2016

Zyprexa (olanzapine) "In 2010 I take Zyprexa 20mg for 2 months. Now I manage to eat one meal a day cause I got diarrhea up to 5 times per day. I'm surprise to be alive. I hate so much what Zyprexa did to me cause it's so awful."

1 / 10
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  • Anonymous
  • April 20, 2012

"I was prescribed olanzapine as an off-label mood stabiliser for clinical depression. It took away all my positive emotions, leaving me feeling permanently "grey" and essentially soulless. I lost interest in all activities I previously found enjoyable. In four months of "treatment" I'd gained 4 stone, and couldn't stop eating. Only now am I coming off this, a process which has been extremely difficult due to a resurgence of the condition the medicine was treating. "

1 / 10
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  • Anonymous
  • July 26, 2015

Zyprexa (olanzapine) "Zyprexa brought me out of a severe depression within a day or two. It has also been fairly helpful with anxiety/panic attacks. Unfortunately, I have gained over 40lbs and never feel full. It has also increased my cholesterol and fasting blood sugars. I've also noticed I don't have much energy or drive. Due to the metabolic issues my doctor wants me to try latuda."

7 / 10
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39 Report
  • Symbyax...
  • February 4, 2016

"I took 3mgs of olanzapine every night for five years. This med worked like magic for a couple years, then I started having severe memory issues. This is when I found out the hard way, that quitting this medication without suffering is not possible. So I decided to taper slowly over a period of 6 more months. Even then, after tapering to almost nothing before quitting completely, I had anxiety, liquid stools, confusion, and severe memory problems."

1 / 10
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36 Report
  • Robin...
  • June 20, 2015

"Olanzapine is great for bringing down a manic episode but can hinder recovery as it made me feel so depressed. On 2.5 mg and going to come off as it makes me so low and depressed. I sleep for about 15 hrs and have no interest in anything. It's helped with my anxiety but would rather feel anxious than live with the depression I am counting down the minutes till the day is over. Previous have done this and have felt better within days, longest I've stayed on it this time but also longest I've felt depressed. Will let you know how I get on"

5 / 10
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  • Geoff...
  • February 26, 2021

"I was prescribed 2.5 mg of this medication for sedation. I took it roughly for a week and it caused my hunger to skyrocket. I stopped it and my otherwise mild depression has become unbearable. I am crying and scared. Never felt this bad ever before. I was so better. Hope this ends someday and I am back to my previous self. I am not the only one with such an experience. Can anyone with similar experience please share how long the worsened depression last ?"

1 / 10
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  • jamaas
  • Taken for 6 months to 1 year
  • February 14, 2018

"I have been on this drug for the last several months on 5 mg/day. For most of my life, I have been underweight or at a healthy-weight level (work out on a regular basis). However, with this drug, I am overweight even though I am on a caloric-restricted diet. This drug initially caused a noticeable increase in suicidal thoughts and ideation as well. Eventually, it wore off for the most part. However, I no longer feel anxious but I also kinda feel "empty" inside -- I don't feel fully human, almost like a robot. I am trying to get off this medication because I felt that while it did improve my depression/anxiety - it robbed me of my motivation, personality, and a fully functional brain. My cognition has taken a noticeable decline since on this medication -- I feel like I stepped back into the 7th/8th grade, mentally. Also, short-term memory has significantly declined."

4 / 10
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  • Shyllie
  • Taken for 1 to 6 months
  • July 24, 2015

"Zyprexa has given me my life back in 4 weeks! I have the worst panic attacks ever, anorexia and chronic nausea!! I have been on every medication under the sun with no relief, if not worse nausea because of the side effects of all the medications. I was on Klonopin, propranolol, hydroxyzine, and zofran every single day and I was still having really bad nausea and panic attacks so bad, I could not leave my house. Dr. prescribed Zyprexa 5mg and after 3 days, I started eating again. I have already gained 2 lbs but I needed to because I was so nauseated I couldn't eat. I'm so excited that I can eat again without feeling like I'm going to vomit!! I hope it doesn't "poop-out" on me bc It's been a miracle!!"

10 / 10
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  • Mola
  • October 21, 2016

"On this drug which I've taken for a just a few weeks, I have now developed a chipmunk memory. I can barely remember anything past 3 or 4 seconds, and I feel as though I almost can't think or hear my own voice in my head. Hopefully these effects will change when I'm off it, but as of right now, I don't feel quite normal yet."

1 / 10
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  • Eduardo
  • August 23, 2016

"This drug was prescribed to me for depression and anxiety, but it had an unexpected effect. I simply cannot stop eating. I eat the entire day, and right after I finish eating a full meal, I feel hungry as if I hadn't eaten anything, so I eat again and again. I have gained 9 kg in less than 3 weeks and I am loving it. People always make fun of me because I'm skinny, I never thought a psychiatric drug could fix this.. I am so happy when I look in the mirror. Olanzapine is the best drug if you are a skinny ectomorph who struggles with lack of appetite."

6 / 10
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  • Radas...
  • Taken for 6 months to 1 year
  • October 26, 2019

"I was injected with this drug because I had a psychotic episode. It took care of psychosis but it developed tolerance for negative symptoms and depression so I got depressed while on the drug (because your brain stops producing serotonin while on it). Quitting it was very difficult but I managed and now am in remission only with vitamins and nutrients. They can treat mental disorders! You can read more about this in William Walsh'es book "Nutrient power: heal your biochemistry and heal your brain"."

1 / 10
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  • Nikki...
  • Taken for 6 months to 1 year
  • July 26, 2020

Zyprexa (olanzapine) "Zyprexa made me have hallucinations the first 4 nights I had taken it. (Cray, scary) Then they stopped. I gained a good amount of weight (but that didn't matter because I was extremely overweight) So this med basically saved my life. I don't feel 100% better off of it but I do recommend that it's a decent drug. I've tried SO MANY meds and there are some many more worse ones than this."

8 / 10
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  • Dunco
  • Taken for 6 months to 1 year
  • August 9, 2020

"I used 5mg of olanzapine every day for the past 8 months and when I read a little more about it, I decided it wasn't for me. I have been tapering for about 6 weeks and I have now been off it for 12 days and my withdrawal symptoms are so bad I can't do daily things. I look like even canceling my golf game...it is the pits and together with an enlarged Prostate, I get no sleep and feel sick all day. I don't eat much as I don't feel like anything and all I can hope is that these withdrawal symptoms go away SOON. I wish my Dr. would've told me about these issues BEFORE prescribing it to me."

1 / 10
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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.