Kesimpta for Multiple Sclerosis User Reviews (Page 2)

• Ike...
• Taken for less than 1 month
• February 14, 2024

"I have RRMS, this is my 5th med to try. I took the first injection, which of ANY self-injection was the easiest I have ever done (no pain, didn’t even feel it, so kudos there!) waited for the side effects and thought I was home free. I always did great on Ocrevus, like a burst of energy great, so I thought maybe it would be like that. Two days went by and nothing. Then the third day, almost 72 hours exactly, it hit. I got widespread muscle spasms from my back to my toes. I got deep bone and joint pain, even my ear canals and fingernails hurt. I ran fevers up to 104 all night. By morning, I just felt tired and VERY sore for the rest of the day, for 3 days I was very sore and slow moving. Not sure if I can do this since I am a mom, too. But desperate to slow down my progression. Not sure what to do."

• Jay...
• Taken for 2 to 5 years
• November 15, 2024

"Kesimpta has helped me maintain my multiple sclerosis symptoms. Having a monthly self-injection ensures I get my medication. It's easy to use. I've had few side effects from it. I'm grateful I switched to Kesimpta 2 years ago."

• Mel...
• Taken for 6 months to 1 year
• January 14, 2023

"I was diagnosed with MS in 2001. I was immediately put on Rebif, I couldn’t tolerate it! So I struggled with episodes! When my father died, then I started going downhill. Within 2 years, I can’t walk without a walker! I can’t work anymore, and I struggle every day to function! I tried Ocrevus, and I couldn’t get through the first infusion cycle, but then my doctor suggested Kesimpta, and after the first dose, I had immediate improvement! I’m in physical therapy, and never felt stronger! I have a 13 mm oval-shaped lesion that was found over two years ago and has been stable, with no new lesions since taking the Kesimpta, so if it worked for me, there’s still hope for you! Don’t give up!"

• Inf...
• Taken for 1 to 2 years
• April 21, 2022

"I love Kesimpta. Not having to worry about veins being blown out by infusion treatment. I did run a 104 fever from the first injection, but the second and third were fine. I began to feel my feet again after the first injection. Mixed emotions about that. For the time being, I can't really say if I'm slowly getting worse or better. Good and bad days. I did have an icy hot sensation in my leg for a month after taking the first 5 doses, which vanished after steroid treatment."

• Kes...
• Taken for 6 months to 1 year
• May 19, 2023

"I'm on the 7th month of Kesimpta. I was 2 days late for the injection. I got severe, agonizing chills, body pain, and migraine, worse than the loading dose. A week before the injection, usually my best time, my heart rate went down so low I was afraid to go to sleep, my urine was dark even when drinking lots of water, and my body hurt. I wish doctors would approach prescribing Kesimpta with these side effects in mind. It feels condescending to be told that these side effects are acceptable and don't require anything beyond ibuprofen. If I had to do this more than once a month, I'd quit. Bimonthly dosing would be great. I'm worried about my organs. I haven't had an MS flare since starting, but the injection itself is worse than having one. I'm getting an MRI in 3 months, and I'll know if I should stay on it. The only reason I recommend it is that there aren't incapacitating stomach effects like Tecfidera or multiple injections like Copaxone."

• Gre...
• Taken for 1 to 2 years
• June 27, 2023

"I have been on Tysabri, Tecfidera, and Gilenya. I had liver issues with Gilenya, anaphylactic shock with Tecfidera, and Tysabri was OK, but it was too time-consuming to get the monthly infusions. Kesimpta has been by far the best medication I have taken to treat RRMS. I have been on this for over a year and had one minor flare-up, which was easily treated with a pill steroid. I am very happy with this drug, and I haven't felt better since my diagnosis in 2015."

• Mar...
• Taken for less than 1 month
• July 15, 2023

"I have completed the loading doses for the first three weeks. This week is my week off before the permanent fun begins. First reactions were pretty miserable. About six hours after my injection, I started shaking and was absolutely freezing. I had a mild fever, about 1°. I could not get warm, and I live in South Florida! The shaking stopped after a couple of hours and then I started getting really hot. I had a couple degree fever by then. And I was hot, hot, hot. By mid-afternoon the next day I felt 90% fine. The second injection was way better and I only got a mild fever and a headache. The third week was better still. A mild headache and about a half a degree fever. But now, during my off week, I have been feeling really tired and frequently mildly nauseous. I don't know what that means. Overall though, I feel like this is way easier than how I felt during my 14 years of Avonex."

• Kes...
• Taken for 1 to 6 months
• April 19, 2023

"Being realistic about MS meds and side effects, I know they cause pains, fatigue, and other unfavorable side effects. I got through the loading doses, the side effects were akin to having a short but very severe flu. I was prepared for that. I tend to feel like a normal person towards the next dose when enough time has passed. I like not having constant severe pain like I did on Copaxone. However, I wish that medical professionals would stop minimizing and undertreating the pain of this disease and how it can be further aggravated by taking DMDs. There are times on Copaxone and Kesimpta that I dread the myalgia resulting from the scheduled dose because I know the Aleve or Advil the doctor or nurse has emphatically declared will cure, won't fully help. The increased risk of sunburn was surprising, and the constant scalp irritation, even with intense conditioning and hydration, has been baffling. That being said, I'm still grateful to be functional with a medicine that only requires once-a-month dosing."

• Don...
• Taken for 1 to 2 years
• August 13, 2023

"Have been on Kesimpta for 20 months (I am 67). No side effects even with loading doses. At about the 10-month mark, I felt like I turned a little corner and was fully in my system. Only thing is I feel like my walking has declined over these 20 months. It's easy to use and painless, and some months I feel pretty good. Just concerned about the decline in walking, so I am trying to increase my daily steps to see if that helps. Overall, I like it."

• Zoa...
• Taken for less than 1 month
• June 12, 2022

"Felt awful after my initial dose and had signs of an allergic reaction, so I was given antihistamines and an EpiPen for my second injection, but it was absolutely fine. No side effects. Was on Tysabri for the past 7 years, which I loved, but my JC virus score was increasing too much."

• DLe...
• Taken for 1 to 6 months
• April 25, 2023

"The medication has a positive effect on my condition. My mobility has improved greatly, which I'm more than thankful for. The negative that I've experienced is currently a breakout on the back of my right hand, a small reaction on my left hand, and both my arms. These are a small irritation, which I'll happily deal with for the positive effects the medication has had on my overall condition."

• Ang...
• Taken for 2 to 5 years
• December 9, 2024

"Starting Kesimpta 3 yrs ago brought me back from the brink of being nearly wheelchair-bound. I have had a huge increase in catching every sickness, but I do have an elementary-aged child, lol. One thing I didn't notice until missing a full month's dose (bc recurring sickness) is increased leg pain. When I finally injected my dose, I was so overwhelmed with pain, like how did I live like this?! But like before, I became accustomed to this level of pain in about a week or two. It's not all sunshine and rainbows, and it doesn't work for everyone, but the benefits outweigh the costs for me. Also, I feel like a hot, soggy dumpster for a day or two after my dose. But it beats the side effects from other meds I've tried."

• Nat...
• Taken for less than 1 month
• December 28, 2023

"I just had my second dose of Kesimpta yesterday. It's fantastic. I was previously on Ocrevus for a year and a half, and it floored me every time for at least a week. I had to take time off work as I wasn't able to function. Kesimpta is a game changer for me. No side effects for me, and it's super easy to self-administer. I am over the moon with it and cannot recommend it highly enough."

• Gli...
• Taken for 6 months to 1 year
• March 25, 2023

"Has effectively stopped further MS activity as shown on MR tests. However, after four months of use, I have developed side effects: severe pain in my leg, like flashes during the night and lasting about three weeks, after sore foot and burning sensation on the upper side of the foot. Tried massage (professional), which seemed to help. Experience “trigger finger symptoms” in both hands: thumb and point fingers. Also, burning sensation in the leg muscles when getting up from a chair/bed. I have some cramps in my feet and lower legs. Calf muscles locking. Goes away when standing up. Have been using Kesimpta since July 2022. So, 9 months. Dosage 1/month. Very easy to use. No side effects when taking the medicine (within 24 hours) so far."

• LuL...
• Taken for less than 1 month
• May 20, 2022

"I have taken my first dose two days ago. Due to COVID, insurance, and medication shortage, I was without any medication for 7 months. Begged for a steroid treatment, which I hate, and my neurologist wouldn’t do it. I have been nauseous, with a mild headache, very tired, and HOT! It’s humid here (SC), and the night sweats were so bad. The reviews have been helpful. I will know more when I get to my second and third dose. Not given up yet. Keep your fingers crossed!"

• Mar...
• November 4, 2022

"Have been taking for 14 months. Periodic stints of feeling a little better and able to get around pretty well without my cane. Yesterday I got bold and raked leaves in my yard. Today I can hardly walk. Back to my cane again. The last couple of months my sinuses have been excessively, constantly draining. My PCP started me on an antihistamine and Mucinex. Had no positive results. Then I researched potential side effects of Kesimpta, finding nothing listed for Kesimpta and sinusitis. Then I researched Ofatumumab extensively. I did find that Azerra was the name of the Ofatumumab given for CLL (Chronic Lymphatic Leukemia). Found several sites indicating sinusitis was a common side effect of Azerra. One listing indicated saline nasal spray may be beneficial. I did try the saline nasal spray with extremely positive results. Finally, I am able to sleep without choking on the continuous nasal drainage that woke me up frequently at night. Now I am able to do things around my house."

• Ter...
• Taken for 6 months to 1 year
• October 26, 2022

"Started in late Jan. Got sick (fever, flu-like symptoms) only after the 1st dose and have had no problems since then. I do take ibuprofen and Benadryl 1 hour before injection, and I inject at night right before bed. Too soon to know if it's working, but very easy to take."

• Cc1...
• Taken for less than 1 month
• January 22, 2023

"First time taking my Kesimpta injection last night, it was painless and was fine for the first hour. After 1 hour, I had chills and back pain. After 4 hours, I had a fever that got to 101.09 and went to bed using an ice pack. That helped and took the fever down. The next morning, I felt 100%, but I have itching on my face. Going to call the doctor to see if this is serious. Hope everyone is doing well, and good luck."

• Jus...
• Taken for 6 months to 1 year
• May 1, 2023

"I have been on Kesimpta for 10 months so far. I recently had more scans and found out that I had new lesions and have developed numerous black holes throughout my brain. The damage may have occurred prior to starting treatment, but overall I do feel a bit better, so I am continuing treatment. The only side effects have been fatigue and fever for 3-5 days after injection."

• Kes...
• September 1, 2022

"It's not working, I have gotten worse. Since I was taking Tysabri but got the JCV virus from that, I had been on that for 13 years. The Kesimpta, my legs are feeling like they are on fire. Once I stand in the morning, after a few minutes my legs go numb! Right now, my toes on both feet feel like they are on fire, can't stand this!"

• HHD...
• Taken for 2 to 5 years
• July 24, 2024

"I feel that it's been working very well for me. I take it once monthly at home. In the initial build-up phase, I had some very minor breathing tightness and stomach problems, but that ended after I reached maintenance level. Recently, I've had some infections that I haven't felt I needed to take antibiotics for, just working on natural solutions, and they're improving. Otherwise, I'm very happy with the medication; it's easy to take, just once a month at home with no negative aftereffects, and I just go on with my day."

• Dia...
• Taken for less than 1 month
• November 28, 2022

"I have finished the 3-week shots. Each time, it did get better. I still get tired on the 5th or 6th day after the shot. I was taken off Ocrevus because getting an infusion all at once was shocking my body, and I have a weak stomach to begin with. In the beginning, I know there will be some side effects until your body gets used to it and trying to work with it. I am hoping this will keep my MS steady. Good luck, everyone. Think positive."

• Sta...
• Taken for 1 to 2 years
• May 3, 2023

"I have been on Kesimpta for 2 years. I have a bit of a love/hate relationship with it. Pros are it was only one jab a month after the initial start-up jabs. Minimally impacts my life, and it’s quick and simple. Cons are that it stings when I do the injection, and I immediately get a 24-hour headache the minute it hits my system. I do get a little more poorly if I get an infection."

• IHa...
• Taken for 1 to 6 months
• April 27, 2022

"About to take second dose. I don’t like how I feel on this drug. Migraines are worse. I’m more fatigued. I began the drug because of its ease of taking once a month via self-injection. I wanted to go back to work full time. However, I’m too tired to do the job. Can’t think clearly because I’m too fatigued. Going back to Tysabri."

• Dar...
• Taken for 6 months to 1 year
• March 15, 2024

"I was diagnosed with RRMS. I've been on Kesimpta for 10 months, it is very convenient and easy to administer. So far, I've had no issues with Kesimpta. My recent full MRI showed no further progression."