CD20 monoclonal antibodies
What are CD20 monoclonal antibodies?
Monoclonal antibodies used in immunotherapy are produced artificially from a cell clone therefore consist of a single type of immunoglobulin. They are targeted towards specific antigens and bind to the antigens to form a complex. The complex can be recognized and destroyed by phagocytes or used for other diagnostic purposes. Natural antibodies are proteins made by the B-lymphocytes in response to antigens. Each B-cell makes only one type of antibody. For therapeutic purposes a significant amount of a particular antibody is needed. These are obtained from a culture that gives a one type of antibody, which are called monoclonal antibodies. CD20 monoclonal antibodies are targeted against B-cell antigens, and were originally developed to treat B-cell Non-Hodgkin's lymphoma.
List of CD20 monoclonal antibodies
| Drug Name | Avg. Rating | Reviews |
|---|---|---|
| ocrelizumab systemic (Pro) Brand name: Ocrevus |
195 reviews | |
| rituximab systemic (Pro) Brand names: Rituxan, Truxima, Ruxience, Riabni |
175 reviews | |
| ofatumumab systemic (Pro) Brand names: Arzerra, Kesimpta |
79 reviews | |
| ublituximab systemic (Pro) Brand name: Briumvi |
14 reviews | |
| obinutuzumab systemic (Pro) Brand name: Gazyva |
9 reviews | |
| ibritumomab systemic (Pro) Brand names: Y-90 Zevalin, Zevalin | No reviews | |
| hyaluronidase / rituximab systemic Brand name: Rituxan Hycela | No reviews | |
| hyaluronidase / ocrelizumab systemic Brand name: Ocrevus Zunovo | No reviews | |
| For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective). | ||
See also
Medical conditions treated or associated with CD20 monoclonal antibodies:
Further information
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