Skip to main content

Systane Ultra and Headaches: What Users Say

Headaches: mentioned by 4 users (10.8%)

Based on user experiences from 37 Systane Ultra reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

burning 18.9%
itching 18.9%
blurred vision 16.2%
redness 13.5%
headaches 10.8%
pain 10.8%
dizziness 8.1%
swelling 8.1%

Reviews for Systane Ultra

Commonly mentioned side effects
  • Mat...
  • October 17, 2016

"I was advised to use the Systane Ultra by my optometrist, but the irritation it caused and splitting and crusting of the skin around my eyes has been unbearable. The skin around my eyes is itchy and crusty and splitting at the corners. My vision is blurred and worse for using it. It will take a few days to settle down, it seems, but I won't be using it again!"

1 / 10
Was this helpful?YesNo
11 Report
  • Jka...
  • Taken for less than 1 month
  • October 9, 2019

For Dry Eye Disease "Dr. told me to use this 2 times a day for dry eyes every 12 hrs. 1st day it seemed to help, had a bad headache. 2nd and 3rd day, by 4th day my right eye hurt and was so irritated, and my eyes were so blurry after reading these reviews. I stopped the Systane. My eyes are still bothering me, but I’m 100% sure my eyes are more blurry and irritated than they were. These drops might help some people, but I wish I would have never used them."

1 / 10
Was this helpful?YesNo
8 Report
  • Jen...
  • September 25, 2021

For Dry Eye Disease "Almost from the beginning, my eyes felt better for a few days, but on the third day, I noticed my eyes stayed swollen, red, began to have headaches, crust around my eyes, and now I can’t see as well, so I have to have stronger eyeglasses. Also, I noticed the outer rim around my iris continues to thicken. These drops are horrible, and I do not recommend them to anyone, and they should be taken off the market."

1 / 10
Was this helpful?YesNo
6 Report
  • Lor...
  • Taken for 1 to 6 months
  • March 13, 2021

For Dry Eye Disease "Prescribed for red, dry, irritated eyes. Been using as prescribed, disappointed with results-blurred vision and slight headache. Found that it had crystallized in the corner of my eye. Not going to use them from here on, very expensive, normal saline would do."

2 / 10
Was this helpful?YesNo
5 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.