Ocrelizumab User Reviews & Ratings (Page 4)

• Anonymous
• Taken for 6 months to 1 year
• April 24, 2021

Ocrevus (ocrelizumab) for Multiple Sclerosis "I was diagnosed in August 2020 with PPMS at the age of 51. Ocrevus is every 6 months. I had half infusions on 9/16/20 and 9/30/20, respectively, and my first full infusion on 3/29. No infusion reactions at any time. I'm curious to know what all reviewers with negative comments chose to do: get Ocrevus or not? I have seen no new lesions on MRI, but feel my symptoms are much worse, and I'm curious what everyone who responded negatively chose to do?"

• Bet...
• Taken for 6 months to 1 year
• May 2, 2020

Ocrevus (ocrelizumab) for Multiple Sclerosis "Properly diagnosed PPMS last Sept. Had first Ocrevus two (split) treatments in November. Had MRI before first full dose, which showed new lesions on the brain. Infusion was 2 weeks ago and feel so fatigued, but will see what the next MRI shows. I’m going to keep persevering with the Ocrevus - this fatigue may be short term. I have not noticed any other difference, except I’m not tingling as much. I’m in Australia and it doesn’t cost anything."

• Car...
• Taken for 1 to 2 years
• October 20, 2020

Ocrevus (ocrelizumab) for Multiple Sclerosis "Please read this if you are thinking of stopping your Ocrevus treatment. First half infusion (pre-COVID): slight fatigue after it, had to work from home for a few days and sleep a lot. Second half infusion: horrible side effects: off work for 10 days as a result. Spent my birthday in bed :( I told myself I would never use this drug ever again. Was not possible to switch, so did not have any other choice than to stick to it. First full dose infusion (about 10 months later due to COVID): I went to the hospital reluctantly, expecting the worst again... but to my surprise, I did not need any time off work after the infusion, I have felt more tired for sure, but nothing unbearable. So give it another try if you are hesitant. My MRI shows no new lesions and some have shrunken..."

• Deb...
• Taken for 2 to 5 years
• April 1, 2020

Ocrevus (ocrelizumab) for Multiple Sclerosis "Living in Australia, Ocrevus is PBS listed... so no cost involved. I started this drug in November 2017. I was diagnosed with RRMS at the start of 2017. I have pain in my wrists for a couple of days after the infusion. If that is a side effect, I am happy with that, as I have no other side effects. I have also had no progression on my MRI. Yes, I'm tired, but who isn't? I still work full time as a nurse."

• MSi...
• Taken for 2 to 5 years
• March 12, 2022

Ocrevus (ocrelizumab) for Multiple Sclerosis "I had 4 infusions, 2 years basically. No initial bad symptoms first time. Noticed a huge onset of symptoms about 2 months prior to the second infusion. Afterwards, back to regular symptoms. That lasted for 4 months also. Then all hell broke loose in my GI system. I haven't been normal since. I've lost almost 50 pounds, devastating my powerlifting hobby. I can't hold food in my body, so I'm always exhausted. I don't blame my doctor, and I know it's worked amazing for some people, but it is not a miracle. Please stop advertising this dangerous drug as a cure for MS. I take Gilenya now, but I will never be the same."

• Pik...
• Taken for 1 to 2 years
• April 2, 2019

Ocrevus (ocrelizumab) for Multiple Sclerosis "Diagnosed with multiple sclerosis in 2013. Taken Tecfidera, Gilenya, Plegridy, & Ampyra. I'm 55, with PPMS (primary progressive multiple sclerosis) and started Ocrevus 7/2017. The first dose lasted 3 months, second dose 2 months, and the third dose 5 weeks. The fourth dose in 2019 has done nothing at all. Lost my job, now walk with a cane, balance & pain worse. Six months is too far apart for my condition. I am worse now than when I started it. I'm totally finished with it. Mayzent will be next, a daily pill for SPMS (secondary-progressive MS)."

• DTT...
• Taken for 1 to 2 years
• December 10, 2019

Ocrevus (ocrelizumab) for Multiple Sclerosis "I just took my 4th dose of Ocrevus. I have had PPMS for 20 years now. I have done chemo/steroid treatments (those worked best for me) and many of the injections. I also used CellCept for a number of years but was prone to infection while on it. The first three infusions did nothing, but they didn't hurt either. Having PPMS and nothing happening is a good thing. However, this last infusion, anxiety and depression hit me like a ton of bricks. I hope it wears off because I take enough meds without adding antidepressants to it."

• Rei...
• Taken for 1 to 2 years
• February 5, 2019

Ocrevus (ocrelizumab) for Multiple Sclerosis "Switched to Ocrevus after becoming JC+ on Tysabri after 6 years. While I don't know the efficacy in terms of disease progression, almost all symptoms have increased in intensity since the change. Tysabri was effective in slowing progression; would switch back if I could."

• Sta...
• Taken for 6 months to 1 year
• November 23, 2020

Ocrevus (ocrelizumab) for Multiple Sclerosis "I received my first full Ocrevus infusion for MS in September. Wow! This brought me from using a cane daily and a wheelchair as needed to not using a cane at all and being able to get a part-time job. I see it as a miracle, in my opinion. It’s brought me from the first up to daylight."

• Mad...
• Taken for 2 to 5 years
• July 26, 2021

Ocrevus (ocrelizumab) for Multiple Sclerosis "I started this medication in 2017 and finally quit in September 2020. Although my MRIs remained stable, I declined physically. I walked into my first infusion unaided, now I need a full-time cane/walker and a scooter. My mobility has been most affected, other symptoms, which I could have lived with, include hair loss, fatigue worse than usual, and cystic eye styes. The worsening of mobility, balance, and weakening of muscles has made choosing this drug the worst decision I ever made. If I didn’t do CrossFit every day, I’m sure I would be bedridden."

• Tru...
• Taken for 1 to 2 years
• August 5, 2018

Ocrevus (ocrelizumab) for Multiple Sclerosis "I was diagnosed with MS in very early 2002, almost 7 years after my one (and thus far only) MS episode, which for me was optic neuritis. Nevertheless, brain MRIs show numerous lesions, and my quality of life has taken a substantial hit, resulting from severe fatigue, sexual dysfunction, an episode of severe depression and anxiety, which took almost a year to get under control and for which I'm still receiving treatment, etc. In a sense, I can say that the three MS therapies that I've been on have been equally effective because I have yet to experience a relapse while on any of them. I switched to Ocrevus based on my conclusion that MS continues to damage your CNS whether or not you are aware of symptomatic changes. And I thought that it was time to switch to a therapy that is believed to be more powerful than many. I have been very pleasantly surprised by the minimal side effects that I've experienced thus far. So, I am able to report that I'm happy with my Ocrevus experience."

• Pet...
• Taken for 1 to 2 years
• December 7, 2018

Ocrevus (ocrelizumab) for Multiple Sclerosis "I have been on Ocrevus for 1.5 years. I just had an infusion three days ago. As with all MS meds, you are never sure if it is doing anything. I have no new lesions and seem to have areas in my legs that I can feel. My hands have not changed. Still numb, and fatigue is the same. Over the 20 years, I have taken Betaseron, Copaxone, and Gilenya. Betaseron was the worst. Copaxone was good. I really am unsure if there has been an improvement by any. I just get worse and pay a lot of money."

• Mic...
• Taken for 6 months to 1 year
• October 15, 2020

Ocrevus (ocrelizumab) for Multiple Sclerosis "I had optic neuritis as my first and only real symptom. I got more headaches and some orbital pain periodically after that - there was a little bit of burning sometimes in localized areas in my head that I am not sure how to explain. They said I have tumefactive MS. After taking Ocrevus, the headaches and eye orbital pain went away. I think I had a couple of muscle twitches, but I don't know if that was anxiety from taking the medication and being worried about getting an infusion reaction. So overall, this was a very good experience, and I had no issues taking it, no reaction to the infusion, and my headaches mostly went away :)"

• Jdr...
• Taken for 2 to 5 years
• May 26, 2021

Ocrevus (ocrelizumab) for Multiple Sclerosis "I've been on Ocrevus since June '19. This drug has been a game changer for me. On my last MRI, it showed absolutely no new lesions. I have no pain, my gait is much better, and I very rarely get tongue-tied. Ocrevus has made me feel 'normal.' I realize that everyone will react differently, but I honestly couldn't be happier."

• KJa...
• Taken for 1 to 2 years
• August 25, 2018

Ocrevus (ocrelizumab) for Multiple Sclerosis "I’ve been on Ocrevus now for one year. Like all MS drugs, who knows if it is working except by MRI scans and the hope for no new lesions. It is very convenient for me, just a twice-per-year infusion. I’ve had no side effects, and using it has been a positive experience. No rash like Tecfidera, and no pills. I feel fortunate that I tolerate it well."

• Lor...
• Taken for 2 to 5 years
• March 20, 2023

Ocrevus (ocrelizumab) for Multiple Sclerosis "Diagnosed in 2019 with PPMS at age 61. Started them right away. Seven doses later, I’m going to stop now because of chronic sinus infections following Covid. I felt it was showing me how hard it is to fight infection. Now, thinking at my age, I would be better off without taking them, and the neurologist agrees. I have tolerated infusions pretty well. It’s time to make a decision because five months of this with no end in sight versus a more severe infection is not ideal! Every day counts for MS patients."

• 102...
• Taken for 5 to 10 years
• January 22, 2024

Ocrevus (ocrelizumab) for Multiple Sclerosis "I have RRMS that was extremely aggressive. After years of unsuccessful medicines, I tried Ocrevus. It has changed my life. I am basically normal now, when I could hardly walk when I started it. So, so grateful."

• Dod...
• Taken for 1 to 6 months
• October 11, 2024

Ocrevus (ocrelizumab) for Multiple Sclerosis "I took my first full dose of Ocrevus, and I have nausea, diarrhea, fever, chills, tiredness, and no appetite for a week. The infusion went great, it was the aftereffects that have me concerned. My doctor told me it was a GI issue, and there was nothing he could do for me, yet he is the one that prescribed the infusion and should know how to handle any side effects if he is going to use the product. I did really well with the small dosages at first. I was really tired for about 48 hours but had no other side effects."

• lan...
• Taken for less than 1 month
• October 13, 2024

Ocrevus (ocrelizumab) for Multiple Sclerosis "I am newly diagnosed with MS and have experienced two flare-ups in 4 months. I have reduced feeling in both lower legs but feel so lucky this is the only long-term effect I have so far. I just had my second loading dose of Ocrevus. During the first dose, I had a slight facial reaction where my jawline became very itchy and red, but this went away by slowing the rate down and having a small break. My second dose had no reaction at all. I haven’t experienced any flu or cold feelings, but do feel pretty knackered. The antihistamine didn’t knock me out like it seems to for others, the steroids also didn’t keep me awake that night. I am wholeheartedly optimistic and believe that the treatment will work to slow everything down because it has to. I worry about the future, but I think that MS forces you to live in the present, which is no bad thing. Hopefully, in the next 6 months to a year, Ocrevus will evidence that it’s working for me. Best of luck on your choice too."

• Kyl...
• Taken for 1 to 2 years
• November 12, 2020

Ocrevus (ocrelizumab) for Multiple Sclerosis "I was diagnosed with MS in 2018, and I have only been on Ocrevus. It has been amazing. My neurologist said he wanted to go aggressive with treatment, and that was Ocrevus. The only reaction I've had was itching and nausea, both passed. Some days I can walk short distances without my cane or walker. I have an MRI in December and am hoping for no new lesions. All the bad reviews on here coaxed me to share my story. I did 6 months of PT and continue the at-home exercises, but for me, Ocrevus has been a godsend."

• Jun...
• Taken for 1 to 2 years
• November 2, 2019

Ocrevus (ocrelizumab) for Multiple Sclerosis "I have secondary progressive multiple sclerosis, and I have gotten 4 doses, and Ocrevus hasn’t helped my SPMS. I have noticed that every injection I’ve had, my hair is getting thinner, and my hair falls out quite a bit. I’m going to talk with my neurologist about the problems I’m having and not feeling it’s helping me. My first 1/2 dose, I felt great and wasn’t so tired."

• Kyl...
• August 11, 2020

Ocrevus (ocrelizumab) for Multiple Sclerosis "I have RRMS. I did 2 infusions of Tysabri and got scared from my high JC+ test. Switched to Ocrevus and I’ve had NOTHING happen with me. Some mild symptoms for the first couple of months. But nothing at all. This is my first year of being diagnosed, and I’ve done my two half doses. I just hope it’s still all good after my first full dose. I’m a little concerned with a study I was looking at about “prolonged use of Tysabri might make your switch to Ocrevus HARD” (can’t remember the exact statement), but basically I read that taking Tysabri for more than 3 months and then switching can make your MS worse. I’m just glad I switched because if that’s true, I was not informed by any doctor."

• Joa...
• Taken for 1 to 2 years
• January 24, 2021

Ocrevus (ocrelizumab) for Multiple Sclerosis "PPMS. Been on Ocrevus about 2 years. No side effects, and so far, no changes on MRI, but MS disability progression is pretty steady. Have gone from walking maybe 1/4 mile with 1 cane to about 1/10 of a mile with 2 canes in these two years. But with MS and DMDs, how do you know? If I weren't on it, maybe I wouldn't be able to walk at all by now. There is no way of knowing. For that reason, I rated it as a 5. One thing I've noticed is some claiming that they have improved on this drug. People, NO MS drug can do that. All any of them can offer is slowing, or, at best, stopping disease progression for a while. The only treatments that have shown the ability to reverse MS damage are stem cell therapies, and the jury is out on them AFAIK. Please be realistic with your expectations."

• Anonymous
• Taken for less than 1 month
• February 7, 2019

Ocrevus (ocrelizumab) for Multiple Sclerosis "Just started my first infusion, and I noticed a difference in my energy right away! No side effects for me either. I even went to the gym that night after the infusion. We will see at my next scan if it is working for me as far as lesions."

• Mys...
• Taken for 1 to 6 months
• March 27, 2020

Ocrevus (ocrelizumab) for Multiple Sclerosis "I am on my six-month dose of Ocrevus and haven't had any noticeable side effects. I was a little overdue for my dose, and some spasticity started to get a little worse, but not too bad. According to my neurologist, I have had no progression on my MRIs since I started Ocrevus, and prior to that, I had had progression on them every six months. So all in all, I think that things are going well. I only have to go in twice per year, the cost is less overall (for my insurance) than the other two treatments that I was on (Avonex and Tecfidera), and I don't have to worry about forgetting."