Nystatin and Dry Mouth: What Users Say

• Kay...
• June 30, 2019

For Oral Thrush "I was on antibiotics for an extended time and after 4 months, I developed thrush. After starting this medicine, I noticed my mouth became extremely dry, especially at night while sleeping. My tongue had a funny burning sensation and everything tasted odd. Has anyone else had this same problem? Also, I got really bad diarrhea and stomach cramps."

• Dal...
• Taken for 1 to 6 months
• September 6, 2020

For Oral Thrush "Just finished my 2nd bottle of nystatin for oral thrush. Ever since then, I wake up with severe dry mouth. My heart even skips a lot now. This dry mouth is so bad, when I sleep, it is horrible. Now, not sure if the oral thrush is even gone. Now on my 3rd 14-day treatment with this junk... Seems to get rid of thrush for only a week or so. May have to do pill next. Pill can cause heart issues though, so trying to avoid it."

• Inv...
• Taken for less than 1 month
• June 15, 2021

For Oral Thrush "So far, I’ve been on Nystatin “mouthwash” for 4 days, and it’s been miserable. My mouth is so dry it’s uncomfortable, and my tongue feels raw and dry. Nothing is helping, so I’m beginning to wonder if this side effect isn’t from overusing. My thrush cleared in 2 days with this, so by all means, it’s amazing for oral thrush, but I’m beginning to wonder if it’s not just burning my tongue since there’s no longer thrush in my mouth to fight. That rubber banana flavor is quite literally vomit-worthy. My tummy has been making LOUD noises, and like others, I’ve had a few strange heart palpitations after taking it, but it DID work (4ml 4x daily) to clear the icky. I cannot wait to be done with it."

• pff...
• Taken for 6 months to 1 year
• April 3, 2023

For Oral Thrush "After the use of inhaled steroids and having a dry mouth for 8 months, I used nystatin four times daily for 12 days. I was religious about keeping it in my mouth for 10 minutes on each side and then swallowed it. Occasionally, I would scrape my tongue. It worked like I hoped it would."

• TJL...
• Taken for less than 1 month
• March 25, 2023

For Oral Thrush "Used this medication religiously as prescribed for seven days. Had to order another bottle as this fungus is persistent. My mouth feels like it's full of dry cotton every time I swish and gargle this seemingly useless medicine! It takes hours to get my mouth to feel moist again, just in time to swish and gargle again!"

• bai...
• Taken for less than 1 month
• May 24, 2021

For Oral Thrush "I took it as a swish and spit for thrush. After a few days, I developed dry mouth and a bit of burning after I took it. Some stomach cramps also occurred. None of these side-effect symptoms were too much, and I finished a 2-week prescription."

• Wil...
• Taken for less than 1 month
• May 31, 2022

For Oral Thrush "Used it for a week as I picked up what I think was thrush after an endoscopy. This didn't work as I've still got a dry mouth and sore throat that won't go away after 4 weeks."