Nystatin and Bad Taste: What Users Say

• Kay...
• June 30, 2019

For Oral Thrush "I was on antibiotics for an extended time and after 4 months, I developed thrush. After starting this medicine, I noticed my mouth became extremely dry, especially at night while sleeping. My tongue had a funny burning sensation and everything tasted odd. Has anyone else had this same problem? Also, I got really bad diarrhea and stomach cramps."

• Mai...
• Taken for less than 1 month
• April 26, 2019

For Oral Thrush "I had oral thrush on my tongue. The Nystatin cleared it in a few days, but since then (6 weeks ago), nothing tastes the same anymore. It's as if it's affected my taste buds and mucous membranes. My tongue feels strange, slightly scalded, and very squeaky against my teeth and the inside of my mouth. It's as if there's enough saliva, but it's not slippery enough. It's really unpleasant. I'm assuming it was the Nystatin that caused it and really hope it returns to normal soon as I don't enjoy anything I eat or drink."

• Vin...
• Taken for less than 1 month
• December 19, 2020

For Oral Thrush "I just started taking the oral Nystatin medication. I just read all the comments regarding not having success with it. I just caught myself taking a sip of water 5 minutes after I swallowed it. I could see that being an issue. Subconsciously, I was thinking how awful it tasted and just grabbed the water. I'm thinking for it to work to the full effect you can't drink anything for 30 minutes, otherwise, I'd be flushing my mouth and not giving the Nystatin time to work on my tongue and throat. Just my two cents. One last thing, I don't like the taste of it going down, and the aftertaste hangs there for a bit."

• Vin...
• Taken for less than 1 month
• December 19, 2020

For Oral Thrush "I just started taking the oral Nystatin medication. I just read all the comments regarding not having success with it. I just caught myself taking a sip of water 5 minutes after I swallowed it. I could see that being an issue. Subconsciously, I was thinking how awful it tasted and just grabbed the water. I'm thinking for it to work to the full effect you can't drink anything for 30 minutes, otherwise, I'd be flushing my mouth and not giving the Nystatin time to work on my tongue and throat. Just my two cents. One last thing, I don't like the taste of it going down, and the aftertaste hangs there for a bit."

• Geo...
• Taken for 1 to 6 months
• April 20, 2021

For Oral Thrush "I am very experienced with oral thrush, mostly due to corticosteroid inhaler use. I've had this bout of thrush now for two months. I'm on my second bottle of Nystatin, and I am still not better. I told my primary doctor it does not help me, but he insists on prescribing this stuff every time. I see my pulmonologist soon, and I will ask him for the troches, as I find I have better results with this medication. Plus, the taste is so much more tolerable! Nystatin is gag-worthy! For the whole day and night, I have such a sour taste in my mouth. It may work for some, but not me."

• Mar...
• Taken for less than 1 month
• March 13, 2022

For Oral Thrush "Developed oral thrush while on H. pylori treatment. The huge amount of antibiotics kills off all bacteria and can make the normal yeast that lives in your mouth get out of control. Mouth was dry, sore, fissures opened up on my tongue, the whole mouth was painful and white spots started to form. On day 3 of using nystatin, I noticed fissures are healing and moisture is returning to my mouth. Only side effects are a weird taste in my mouth. Chemical banana flavor not the best. Nystatin 2.5 ml, 3 times a day, after meals."

• Sil...
• Taken for 1 to 6 months
• October 27, 2021

For Oral Thrush "Wow! I actually found these comments by searching to see if Nystatin causes a horrible taste in your mouth. I was diagnosed with thrush a couple of months ago by my GP after noticing a white coating on my tongue, plus my tongue was burning and I had a terrible taste constantly. No change. Went for my yearly pap and showed my tongue to my gyno, who told me to throw the Nystatin away (I was on my refill at this time), and he prescribed Fluconazole 150 mg. Told me it was better, and it was only one pill. Made no difference. Got the refill on that, still no change. Back to GP...he told me to mix Cepacol and hydrogen peroxide and use as a mouthwash and to make an appointment with my dentist. Used that combo four to five times a day and the coating on my tongue went away, as well as the burning sensation...I thought I was cured. Went to the dentist yesterday, he said I still have it on my gums and the side of my tongue. Made an appointment with ENT...what's up with this medicine?"

• Nic...
• Taken for 1 to 6 months
• September 8, 2020

For Oral Thrush "Nystatin did not help my oral thrush. Horrible, strong taste."