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Naloxone User Reviews & Ratings

Brand names: Narcan, Kloxxado, Rezenopy, Rextovy RiVive Zimhi

Naloxone has an average rating of 8.3 out of 10 from a total of 26 reviews on Drugs.com. 76% of reviewers reported a positive experience, while 20% reported a negative experience.

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Reviews for Naloxone

  • JAB...
  • June 15, 2019

Narcan Injection (naloxone) for Opioid Overdose "I have primary progressive multiple sclerosis and was on opioids for chronic pain. Was on a high dosage for multiple years. I overdosed and was taken to a local ER. They administered IV Narcan to reverse the opioids. It was the most horrifying experience I've ever had. It felt like being continuously electrocuted. My body felt on fire. I pleaded for someone to make it stop but was ignored. I too, like someone else posted, would rather die than to ever feel that excruciating pain again. The Narcan also caused permanent effects on my body. Because stress to the body causes MS symptoms to increase, my disease has progressed significantly. It left me unable to function. I didn't deserve to end up like this."

1 / 10
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38 Report
  • A P...
  • Taken for less than 1 month
  • November 28, 2016

Narcan Injection (naloxone) for Reversal of Opioid Sedation "Singularly, like being electrocuted for 30 minutes! I have CRPS and was getting IV Lidocaine infusions, and was on heavy opioids.......I was near to unresponsive, but breathing, etc., but in a very deep sleep. Ambulance gave naloxone. Set me on fire from head to toe, eyes, everything... I was screaming, no help given... People giving Narcan need to know more about CRPS (complex regional pain syndrome) or RSD (reflex sympathetic dystrophy) and the effects this drug has when reversing all pain meds. I believe it was totally unnecessary to use this. My vitals were fine.... Worst experience of my life, like being skinned and boiled alive. I'd rather die."

1 / 10
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36 Report
  • Jim...
  • May 16, 2014

Narcan Injection (naloxone) for Opioid Overdose "It has saved my life three times in the ER. If it would not have been for this medicine, I would have died a junkie and would not have had the chance to change my life for the better. Thank you for this medicine."

10 / 10
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44 Report

Frequently asked questions

  • Pro...
  • Taken for less than 1 month
  • November 6, 2021

Narcan (naloxone) for Opioid Overdose "I’ve carried Narcan nasal spray for the last three years, after a friend I’d never suspected to have a drug problem had nearly died of an opiate overdose when he’d relapsed. And feeling anxiously helpless about not wanting him to die, I dove into online research and decided that carrying Naloxone nasal spray was something I could do in order to help anyone near me dying as a result of a relapse. He’s never once needed it, but six separate times I’ve administered it to unhoused strangers utterly foreign to my life until I stumbled upon them while I was biking or walking in Portland. Naloxone was miraculous and gave them a bridge that successfully saved their lives by keeping them breathing until an ambulance arrived with paramedics. EVERYONE should carry it. Period!"

10 / 10
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15 Report
  • She...
  • Taken for less than 1 month
  • September 4, 2019

Narcan (naloxone) for Opioid Overdose "My parents administered Narcan nasal to me after finding me with pinpoint pupils and non-coherent. I had snorted what I thought was a 30 mg OxyContin I bought off the streets. But it was fentanyl. I am writing this today because Narcan saved my life! Thank you for this miracle drug..."

10 / 10
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20 Report

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  • Jdi...
  • Taken for less than 1 month
  • December 21, 2022

Narcan (naloxone) for Opioid Overdose "I was given a spray of this in the nostrils after experiencing labored breathing from taking Hydrocodone. A few minutes after receiving the Narcan spray, I was on the floor! I had dripping body sweats, I couldn’t hear, couldn’t move, couldn’t speak, nothing! It was like I was in a coma! I laid there for maybe an hour before this wore off and I started feeling better. I would have rather just dealt with the breathing issues than go through that! It was the scariest experience I’ve ever had. I didn’t know if I was experiencing a stroke or heart attack. All I know is I couldn’t move for an hour! This may help some people but I do t think it’s good for all. I’ve never experienced this kind of horror even when pounding the opioids down!"

1 / 10
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8 Report
  • Eri...
  • November 26, 2016

Narcan Injection (naloxone) for Opioid Overdose "This works too well. The hospital I was at overdosed me on opiates one night while going through multiple kidney failure. The Narcan injection they gave me to spring me back was the most painful experience I have ever had. I hope not a soul on earth has to go through that. Ever. So this product did what it needed to do. Saved my life from an opiate overdose. So it was very effective, painful but effective."

10 / 10
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22 Report

More FAQ

  • Too...
  • August 30, 2015

Narcan Injection (naloxone) for Opioid Overdose "I am a cancer patient and take strong pain meds. One night I had accidentally taken other sensitive type meds and possibly a second dose of narcotic pain meds. My daughter called an ambulance when she couldn't keep me awake. When I got to the ER, my pulse was 30 and dropping at times as low as 20. I could have and probably should have gone into cardiac arrest. I was administered this medicine, and it literally saved my life. I have been battling a terminal but treatable cancer for 3 years, multiple myeloma. I fight every day to stay healthy so I can be here for my kids and grandkids. I don't want to lose my life over something avoidable like an accidental overdose!"

10 / 10
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23 Report
  • Bog...
  • Taken for less than 1 month
  • December 17, 2016

For Reversal of Opioid Sedation "Due to my doctors not listening to my complaints about pain and my mental state, I decided to self-medicate. I obtained 2-50 mg fentanyl patches, which I applied, and took a clonopin for mental reasons. Lo and behold, the two drugs don't mix. At the ER, my vitals started to crash, so they hit me with the naloxone. It snapped me right up and am still breathing today! My lesson learned (the hard way): don't play doctor."

10 / 10
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16 Report
  • Jim...
  • December 31, 2016

For Opioid Overdose "Long story short, I was up for 2 days abusing narcotics. On day 3, I think my body had enough. I was on a car ride when I crashed, me, not the car. My brother was driving and noticed I didn't look well... I was blue. He took me to the ER. Apparently, they told him I would wake up screaming. I did after the injection. It felt like cold water was being pumped into my veins and muscles. I also had heavy muscle spasms. If they held me down, no idea. Everything was going on in slow motion as I came to. They injected me with something to calm the spasms. Then, I was in and out until waking up in the ICU. Nonetheless, it's a lifesaver. It's a painful one, but hey, I'm alive."

9 / 10
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13 Report
  • Big...
  • Taken for 2 to 5 years
  • March 4, 2020

"I was in a bad motorcycle accident that landed me in the hospital for 4 months. After reconstructive surgeries (11), I began to have pain issues. After being forced through the oxy dead-end road, I finally ended up on buprenorphine and acupuncture, and it worked! I was great for 4 years. When my doctor retired, my new doctor forced me to add naloxone to the buprenorphine. I'm having breathing issues now, and this doctor is refusing to remove the naloxone. There are side effects to naloxone use. I don't care what the doctors say."

1 / 10
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8 Report
  • Dob...
  • October 13, 2016

Narcan Injection (naloxone) for Reversal of Opioid Sedation "Severe withdrawal pain for fire burns victim over 65 percent third-degree burns, resulting in increased blood pressure. After several hours, the patient was able to sit up, but not without an extreme burning feeling, as though the fire had just taken place."

8 / 10
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11 Report
  • Tim...
  • September 17, 2015

For Opioid Overdose "I had been taking Valium, crack, and heroin for the day and ended up getting a bit more heroin at night. After I took it, my friend kept telling me I was grey with blue lips, but I was too doped to care! We ended up staying at my house, and I nodded off very fast. I woke him up 3 minutes later by vomiting on him, but he couldn't wake me, so he put me in the recovery position and phoned the ambulance. Fifteen minutes later, they came and found that my heart was beating just 6 times a minute and I was unresponsive, so they pumped air into my stomach and gave me a shot of Narcan. I just remember seeing white lights as my lights were on in my room and the green clothes of the paramedics. They carried me into the ambulance, and when I arrived, they had to give me another dose. It saved my life."

10 / 10
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11 Report
  • Big...
  • January 4, 2017

For Opioid Overdose "After receiving the medicine from the medic, the only side effect I experienced was a very warm sensation over my body that lasted about 1 1/2 hours, that was it. I thank goodness for this medicine, it truly saved my life."

10 / 10
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9 Report
  • Mam...
  • Taken for less than 1 month
  • September 15, 2017

Evzio (naloxone) for Reversal of Opioid Sedation "Product works as expected, very similar to auto-injected allergy medicines. Liquid is visible through clear glass window in center of unit that shows whether or not product is still in usable condition, instructions are written on side of container. Verbal instructions begin as soon as you begin step 1 by removing the cap, follow each step, up through, and including injection, and calling emergency help. Comes in approximately 1/2 inch wide rectangle shaped plastic case is about 2X3 inches. My script came w/two autoinjectors and one test unit for training, which is great. All these came in a canvas travel pouch with a CPR mouth barrier and rubber gloves."

10 / 10
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8 Report
  • Mwt...
  • August 28, 2017

For Opioid Overdose "48 hours ago my fiance and I decided to do Fentanyl just to get high we're not physically dependent and we've actually had some significant clean time in between it was my third time so I knew how strong it has gotten or at least our tolerance wasn't as high as it used to be. It was his second time and being who he is he decided to do more than I suggested which I'm not promoting it I'm just saying normally... I didn't realize I only had some much space to type my experience anyway needless to say it was the most terrifying experience of my life I've never overdosed before and I am just grateful they had they naloxone I had it nasally administered... They said I was on the verge of death. Scary stuff man thank God for Narcan"

10 / 10
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6 Report
  • 999...
  • July 24, 2017

For Opioid Overdose "A friend gave me what she thought was Xanax to help with a panic attack. Spoiler alert: It was not Xanax. I woke up in the back of an ambulance with no idea what had happened to bring me to that point. I had no memory of the past hour or two. I was told my heart had stopped beating and they had performed CPR. I swore to them up and down I had taken Xanax and the paramedics told me that was impossible as they had revived me with Narcan. They treated me like a heroin addict and were not very pleasant. Never trust anyone else when it comes to what you are putting into your body. The most innocent intentions can have severe consequences. I did not suffer any type of pain as a result of the Narcan as others have experienced."

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6 Report
  • Che...
  • May 11, 2017

For Opioid Overdose "I am really unsure how to rate this, because I do not believe I was properly given it in the ER. I was severely overdosing on a barbituate (it is part of my headache medication) and I took too many, ironically even leaving the hospital my head was pounding. I just wanted to rate this so/so, because by the time I woke up after my shot and a rest, I felt somewhat better minus the extreme headache. BUT my boyfriend last year was ODing and when I called EMT's, they were able to successfully resuscitate him !!! Life changing experience, I'm glad he is opiate free still today. Naloxone is a wonder drug for addicts, people who take too much by accident, you name it. You can even get it at the drug store to keep on hand if/when you see an overdose."

7 / 10
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5 Report
  • Ver...
  • Taken for less than 1 month
  • July 5, 2022

For Opioid Overdose "I witnessed somebody being given this medication who had taken a small amount of oxycodone. He wasn’t overdosing, he just didn’t like the feeling and then decided to take naloxone. He got extreme stomach pain within about two minutes, and then lost consciousness. He was convulsing as if epileptic for about 40 minutes. That reaction ended quite suddenly."

1 / 10
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  • Anonymous
  • September 7, 2021

For Opioid Overdose "After using a counterfeit oxycodone I overdosed on fentanyl… my girlfriend found me unresponsive and CPR was given until medical team arrived. I was then given narcan and despite feeling like I was dying for the next hour It absolutely saved my life…"

10 / 10
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1 Report
  • Bob...
  • Taken for 2 to 5 years
  • February 20, 2024

Narcan (naloxone) for Opioid Overdose "I died 56 times. It was once a week on average for the year I was shooting up heroin. I have all the Narcan containers on the wall in my friend's garage. The nasal spray has the worst of the side effects. Your head starts ringing and gets progressively more intense. The taste when it eventually hits the back of your throat is awful and lingers for ages. It seems that the precipitated withdrawals are much more pronounced than they are with the injection (IM/SC). After about a year on heroin, I switched to fentanyl and experienced only 6 overdoses during that following year of daily use. I attribute the lower overdose rate to a more consistent opioid level/quality despite the increased efficacy of fentanyl. Narcan/Naloxone has saved my life so many times, and I’ve used it on at least a hundred other people."

10 / 10
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  • Mom...
  • Taken for less than 1 month
  • April 12, 2019

Narcan (naloxone) for Opioid Overdose "I found my son unresponsive, blue, and barely breathing. CPR was given until paramedics arrived. He overdosed on heroin that was laced. Narcan saved his life!!!"

10 / 10
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14 Report
  • Bdu...
  • May 22, 2014

Narcan Injection (naloxone) for Opioid Overdose "Narcan has saved my life twice in the ER. Every day I rose above the misery of addiction."

10 / 10
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19 Report
  • Anonymous
  • December 8, 2021

For Opioid Overdose "Same as most people set my whole body on fire and wished someone would just end its honestly the most terrifying experience you will ever have in your life"

10 / 10
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6 Report
  • Nar...
  • August 18, 2022

For Opioid Overdose "This stuff had me feeling like I was dying. Like I had ⚡ shooting thru my body for 3 hours and I broke a TV and computer from the shock of my muscles and this was like I had become the exorcist!!!"

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4 Report
Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.