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Singulair and Tiredness: What Users Say

Tiredness: mentioned by 9 users (4.1%)

Based on user experiences from 221 Singulair reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

anxiety 12.2%
depression 10.9%
irritability 8.6%
anger 7.2%
headaches 6.3%
shortness of breath 5.4%
insomnia 4.1%
suicidal thoughts 4.1%
tiredness 4.1%
mood swings 3.6%

Reviews for Singulair

Commonly mentioned side effects
  • Ang...
  • March 9, 2020

For Asthma "Be careful! After years of being misdiagnosed, I was given Singulair. Within 4 weeks, I no longer needed my nebulizer or rescue inhalers. I gradually became more tired and extremely agitated. I began hearing voices in my own home, and I live alone. It got worse, not better. One night, I was convinced someone was in my home. Every light in the house was on. I still kept seeing someone! Coming from a military background and secure in owning firearms, I was searching my home with a gun. I was looking for an intruder who was NOT there! That was my final straw. I threw my Singulair in the garbage. I’m still agitated and frustrated. I am going to try over-the-counter medication deemed safe. I’m not sure how long the agitation and tiredness will last. I pray this will help someone. Please be careful on this medicine. For me, it’s not worth it. In 55 years, I’ve never seen anyone or heard voices in my home until Singulair. (5 weeks total taking it)"

1 / 10
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355 Report
  • Ver...
  • November 5, 2016

For Asthma "Since taking Singulair I have tooth pain, tingling in my face, and a bad metallic taste in my mouth. Plus my anxiety level went up, feel really tired, and very agitated. Stopped taking it last night. Hope these side effects go away soon. This metallic taste is driving me crazy! This is the 2nd time I've tried it. Same side effects and more."

1 / 10
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78 Report
  • Gco...
  • October 19, 2016

For Allergic Rhinitis "My wife was on this stuff for at least a couple of years. She suffered severe tiredness, nightmares, irritability, and even suicidal thoughts, accompanied by severe depression! Although it did make her feel better, the side effects are not worth it at all! She switched to Flonase, and it is just as good. Please, if you are on this medicine and have any of these side effects, please stop!"

1 / 10
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66 Report

Frequently asked questions

  • Cas...
  • April 7, 2015

For Allergic Rhinitis "Been suffering from ETD for about two years. I've been on Singulair for about 4 months, and it has dramatically improved my symptoms, no more ear crackling. Occasional tiredness and headache, but it's tolerable. It has helped me tremendously."

9 / 10
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49 Report
  • Nos...
  • September 12, 2015

For Allergic Rhinitis "I have severe allergies every day right when I get up in the morning. My nose just starts to run and drip. If I do not have tissues, my mucus would just drip on the floor. My allergies always go away around lunchtime. I took generic Singulair (montelukast sodium) every day in the morning. Then I switched to the evening. I may have only missed one or two tablets throughout the 3 months that I took it, but my drip is the same as before. This medication does not work for me. I have tried the generics for Claritin, Allegra, and Zyrtec. Now I have tried the generic form of Singulair. All of these medications do not work for me. The only medication that works is Benadryl, but Benadryl makes me so exhausted and congested."

1 / 10
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39 Report

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  • Anonymous
  • Taken for 2 to 5 years
  • September 21, 2012

For Asthma "This really did help with my allergies and asthma symptoms I sometimes experienced. I took this for 2 years and never on a daily basis, but as needed (when my allergies would act up). It took me a while to figure this out, but I have now determined that when taking this medicine, I am very lethargic the next day, depressed feeling, and extremely agitated. For a while, I had just concluded I was a moody person, but after taking one, seeing how I felt, and then going off of it, I put two and two together. Literally, the next day without the pill, I feel back to my old self. So though it did help for allergies, for me, the pros don't outweigh the cons."

5 / 10
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46 Report
  • Gai...
  • December 24, 2017

For Allergic Rhinitis "This drug did nothing for my stuffy nose, cold, cough, and wheezing, but the side effects are horrible. After less than a week of taking it, I could not sleep, was unable to focus, had a panic attack at the grocery store with sweating and dizziness, felt like I was going to faint, was very tired and achy. I did not connect it to the drug at first, but then I went to take it, and it dawned on me that maybe I should check out the side effects. These are all side effects of the medication. I had lost my mother about a month ago, and I kept thinking I was just not coping well, but once I stopped taking the medication, I was able to sleep and the sweating and dizziness went away. My aches are much less as well."

5 / 10
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  • Hid...
  • Taken for 1 to 2 years
  • May 26, 2023

For Asthma "I was on this for a year with no improvement in my asthma. Two days after getting off of it, I began to have horrific withdrawals, including severe headaches, exhaustion, irritability, weepiness, depression, lightning shocks throughout my body, severe body aches, and inability to sleep. The worst seems to have occurred for 48 hours straight, with no signs of fever or sore throat to indicate flu. After seeing others in forums, it seems to be this medication."

1 / 10
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  • Anonymous
  • Taken for less than 1 month
  • October 1, 2012

For Asthma, Maintenance "I've been taking Singulair for three weeks now after going off Advair, which is no longer covered by my insurance. I now have to use a rescue inhaler several times a day and am constantly coughing, feel out of breath, and tired. Maybe three weeks isn't long enough of a trial period. I'm hoping my breathing gets better in the next week, or I'm calling the doctor to try another medication."

2 / 10
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25 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.