Midodrine for Postural Orthostatic Tachycardia Syndrome User Reviews

• Ben...
• Taken for 1 to 6 months
• October 22, 2022

"Again, unfortunately, not all drugs work well in some. I am 91 years old and was put on midodrine x 3 daily for hypotension (the doctors have only realized I have an underactive thyroid). Side effects of midodrine were dizziness and falling over (broke my back and knee; was told it was age-related), severe anxiety and confusion (was told I have the beginning of dementia), couldn't talk due to breathlessness (was told I have heart failure and COPD - never smoked or drank), and had a heart scan and X-ray 1 month before starting midodrine, no heart problems. Burning all over, insomnia (walking around the house in the middle of the night confused), cramps all over my body (was told I have osteoarthritis), lack of appetite (was told it was age-related). It's a shame doctors, etc., don't want to know or help when you reach a certain age and just tell me I have heart problems, dementia, and osteoarthritis. My grandson stopped the midodrine, and within two days, ALL the above symptoms magically disappeared."

• HS0...
• August 13, 2014

Midodrine "I take 10mg midodrine three times a day for Postural Orthostatic Tachycardia Syndrome. It has changed my life completely. I'm able to be active and do all the things I used to avoid. I go to concerts, movies on opening night, and shopping at places with long lines. I can date without worrying about whether we're going somewhere that I'll need to stand still. There are side effects - weird sensations and goosebumps mostly. The benefit far outweighs any negative effects or risks."

• Lif...
• Taken for 6 months to 1 year
• February 17, 2023

"Midodrine gave me my life back when I was ready to give up. I'm a 33-year-old woman and take 5 mg three times per day, and now I can think clearly, stand up without having to brace myself to prevent fainting. I can stand through 95% of my showers now (was sitting most of the time before). I can walk (even up stairs) at a normal pace without getting completely out of breath. My chronic fatigue and brain fog have dramatically improved. I don't feel the blood draining out of my arms when I lift them above my heart or feel blood pooling in my feet anymore. Even my hair started growing again, and my acne has improved. This has literally been life-changing for me! My body feels a level of peace I've never experienced before. I never got any of the negative side effects others talk about, like goosebumps or tingles. However, the first 3 days on this, I felt really weird and almost quit, but I'm glad I pushed past that and adjusted. I will never be without Midodrine again. It makes life worth living."

• tog...
• October 3, 2015

Midodrine "I have been diagnosed with dysautonomia and postural orthostatic tachycardia syndrome and many other things, but this medicine was my only option. I can't take beta blockers because I need to be able to use my epi-pen, and I had a bad reaction to Florinef, so we decided to try midodrine. It is a lifesaver! I can't go anywhere or do much of anything if I don't take it. I will pass out if I'm not on this medicine, I'm very pleased! I do have to deal with flushing and frequent headaches, but it's very much worth it, the cost."

• Ddo...
• August 17, 2010

Midodrine "ProAmatine is the best thing since sliced bread! Without ProAmatine, POTS patients like me would not be able to function! The side effects are minimal and short-lasting (they usually go away within the first week), and it gives people their lives back!"

• Ano...
• March 22, 2023

"I was on 10 mg midodrine for years for my P.O.T.S. I’ve had this condition for 17 years and am now 70. When I started taking this script, it cost me $450.00 a month! It was extremely hard to come up with that cash, but it was the only thing that worked. (I also take 5 mg of nadolol.) I take 10 mg every 4 hours in the daytime and sleep in a head-elevated bed. My blood pressure rose too high last year, and my doctor took me off of it. It was a struggle. I am back on it now because I had an infection, and every time I get sick, POTS returns with a vengeance. I do feel the itchy and tingly scalp, but that goes away as time goes on. My cost is very reasonable now that I’m on Medicare. I can put up more with this med but still can’t drive because I feel like everything is shutting down, and I can’t concentrate on the road. I never want to be without this medication. It doesn’t make me as strong on my feet as healthy people my age, but at least it is a good crutch for a more normal life."

• POT...
• October 1, 2010

Midodrine "Didn't seem to lower my heart rate very much, except when I tried to walk around in physical therapy class. Then it caused a severe drop in my heart rate, from about 95 in the relaxed sitting position to below the 50s when I walked a few yards. Bradycardia is a documented side effect, and unfortunately, one I suffered from. Also had lots of goosebumps, tingling scalp, chills, and flushing throughout the day. I'm not totally knocking it, because I know it works for some POTS patients, but it wasn't the medicine for me."

• 18...
• Taken for 1 to 6 months
• August 30, 2021

"I love it! Only positive effects for me. Helps my anxiety and dizziness/spotty vision. Also helps with my energy levels too! So helpful! 10/10. Only thing is how often I have to take it: every 4 hours."

• can...
• June 22, 2017

"I get seizures with allergic reactions from mast cell activation syndrome (MCAS), but I didn't when I first took this drug in 2016. Lots of goosebumps, tingling, tight scalp, chills, shivering, and felt like a zombie, though. Became a different person-dissociated, honestly. That'd never happened to me before, was so afraid. Doctor made me try again, seized the entire time, and the tingling burned so bad it felt like I was on fire. Got bradycardic within 2 hours of taking it, too. I get brady sometimes as it is (my heart rate was at 30 the other day), so this medication wasn't a good idea in the first place. Bad call on my doctor's part and bad call on mine for even listening to him."

• Mar...
• February 1, 2012

"Goosebumps on arms, legs, chest, and back; scalp tingling. Reduced my POTS episodes to one or two a month. Wish it were a once-a-day pill instead of every four hours. I take it early morning, lunch, and late afternoon."

• POT...
• August 17, 2011

"Midodrine does not affect postural orthostatic tachycardia syndrome, you need a beta-blocker for that (I am on Propranolol), which keeps your heart from kickstarting the fainting reflex that POTS patients are very susceptible to. Midodrine saved my life, it allows me to literally get up off the floor and get on with life. I have been on it for 10 years, it has a very short life span, so I take both medicines every 3 hours. I am able to function quite well, not super-duper, but I can do most things. If it ever is pulled off the market, I will literally be going to another country."

• Anonymous
• Taken for less than 1 month
• January 4, 2021

"My 19-year-old with COVID-induced POTS tried taking midodrine, and the side effects were not tolerable. One issue is she was freezing cold with goosebumps all over, and they were painful, like a stinging feeling. She only took it for a week, and then we stopped it."

• pot...
• July 21, 2014

Midodrine "Has definitely helped, along with the Digoxin I take, to keep me from feeling faint or dizzy. Has improved my quality of life quite a bit. The side effects (for me) are not bad enough to make me stop taking it."

• Roc...
• Taken for 2 to 5 years
• July 20, 2020

"I was doing well on midodrine for my POTS, but also take propranolol and fludricortisone for it. After a few years, my blood pressure got too high, and my doctor had me stop the midodrine. My POTS is now running my life. I can't even walk around the house without being extremely dizzy."

• Ln2...
• Taken for 1 to 6 months
• October 16, 2020

"Not the drug for me personally. Suffered with POTS for 10+ years, now starting new medicines for it. I was prescribed 10 mg Midodrine to start. No improvement of POTS symptoms and was on it for about a month. No negative symptoms other than goosebumps at first, but after about a month on it, my blood pressure started shooting up and I felt super sick from it. I had high hopes because it helps so many people, but it just wasn't for me."

• Gib...
• Taken for 10 years or more
• May 20, 2024

"I have POTS and as well as fluctuating heart rates, I'd get crazy arterial BP swings - up a little, down a little, and I started fainting at work and couldn't drive. Then I started Midodrine and after a week, the side effects went away and the benefits were amazing. Stable HR and stable BP but it works by increasing venous return in POTS rather than changing arterial BP. Literally kept me employed!"

• kck...
• Taken for 1 to 6 months
• July 19, 2021

"This drug, midodrine, is so short-acting, there is a small window of time that it helps. Am now on 10 mg tid, which is about the max dose. Have added fludrocortisone 0.1 bid to support BP and increased salt intake considerably. The salt really helps, the biggest, quickest way to increase salt intake is soy sauce! Propranolol 5 mg bid, a tiny, tiny dose, takes care of tachycardia."

• Anonymous
• Taken for 1 to 6 months
• August 30, 2024

"Midodrine helps with my tachycardia, but it makes me itch. If I take doses back to back, I have uncontrollable itching. When I first started it, I had an appointment to cut my hair, and the stylist told me I had a head full of scabs and open bleeding spots from all the itching."

• sim...
• December 20, 2009

Midodrine "Rash, goosebumps even when hot, odd blood pressure swings, scalp tingling, and other problems. Was taken off it fairly quickly."

• Lot...
• Taken for 2 to 5 years
• January 19, 2025

"Definitely helps with postural symptoms, make sure to take it regularly (at least 4 hours between), although I did get headaches when my dose was too high."

• Anonymous
• Taken for less than 1 month
• April 20, 2016

"Really bad reaction with me. Severe side effects with little to no results."