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Monistat 3 and Cramps: What Users Say

Cramps: mentioned by 8 users (1.2%)

Based on user experiences from 693 Monistat 3 reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

burning 70.1%
itching 55.0%
pain 18.3%
discomfort 6.5%
irritation 3.6%
swelling 3.3%
stinging 2.3%
allergic reaction 1.2%
cramps 1.2%
tingling 1.2%

Reviews for Monistat 3

Commonly mentioned side effects
  • Anonymous
  • June 11, 2023

For Vaginal Yeast Infection "LADIES!!!! You are not alone or crazy if it is burning you. The package says “mild burning and cramping,” but it is way more than that for me. It feels like hot sauce in my hooha, and the cramps are awful. For me, the only thing that helps is sitting up and icing her!! The burning has been lasting about 2 hours for me. After that, it’s completely normal. I think I will stick to trying to get a prescription pill from here on out… If that isn’t possible, then I will stick to the Monistat creams rather than the capsules, as they don’t cause me anywhere near as much discomfort. Praying for you and wishes for a healthy hooha ASAP."

8 / 10
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5 Report
  • FIR...
  • Taken for less than 1 month
  • June 29, 2017

For Vaginal Yeast Infection "My husband went and got me the three-day Monistat tonight because I have been having some really bad itching. Well, I inserted it and went to bed. Less than 10 minutes later, I jumped out of bed in excruciating pain. I mean, the burning is soooooo unbearable, I am literally in tears. I sat over the toilet and started pushing and wiping with tissue and got a chunk of it out, but I'm still in much pain from the burning. I tried letting the cold shower run over and up into me, and that only helped a bit. What has happened to this brand? I have used this in the past, and all I ever felt was a bit mushy in my panties at night from the cream. I am now having mild cramps and just want to tear my whole vagina out and throw it in the garbage. I will NOT be using this again. Ever!"

1 / 10
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12 Report
  • Ahh...
  • September 17, 2017

For Vaginal Yeast Infection "The first day, I wanted to rip my vagina out. It was the most unbearable pain I have ever felt, and maybe I slept 2 hours the entire night. It was horrible. I wouldn't wish that on my worst enemy. Also, I had some slight abdominal cramping. But in the morning, the itching and burning were gone. I was seriously dreading the second night, but this time, it burned for like 10 minutes, and after that was very slightly uncomfortable. If you can get through the first night, I think the product actually works rather well. Wish me luck that the third night is more like the second."

7 / 10
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6 Report

Frequently asked questions

  • Sti...
  • December 29, 2016

For Vaginal Yeast Infection "So far, I have taken day 1 of the pack. I used the wipe, followed by the suppository, and finally the cream. I had mild itching and burning, but overall, it was tremendous relief compared to the symptoms of my YI. I experienced very minor cramps, which were resolved with Tylenol."

8 / 10
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4 Report
  • Itc...
  • March 26, 2019

For Vaginal Yeast Infection "I used this product for the 1st time last month. Worked great. Had no problems. A month later, another YI. This time I noticed some cramping, but it wasn't until tonight when I was putting the final dose in that it got rough. I have NEVER felt itching like this before. I put it in, stood up, and walked down the hall to my bedroom before the itching started. By the time I got in my room, it was insane. I almost collapsed on the floor, scaring the hell out of my husband as I ran back to the bathroom to sit on the toilet and wipe myself for relief. Luckily, I have some Vagisil anti-itch wipes leftover from my last YI. It seemed to help. I was able to go to bed. But I just woke up to use the restroom. It's been about 5 or 6 hours, and when I wiped, the itching came back. I can't understand why this last dose is different from the other five I took. I'm struggling through it because this is my last dose and it really is working, but it's hard. It's 5:37 and I just wanna go back to sleep!"

5 / 10
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2 Report

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  • ajc...
  • Taken for less than 1 month
  • September 14, 2017

For Vaginal Yeast Infection "I was very scared to use Monistat 3, especially after reading so many negative reviews about it. After the first dosage of Monistat 3, there were already fewer symptoms of the infection, but mind you there was some leakage the next morning and a couple of times throughout the day. However, this does not mean the medication was being rejected, it's normal. I just took my second dosage, and the side effects I experienced both times consisted of minor cramps and minor body twitches. It is best to lay down right after inserting, to reduce the amount of leakage. So far I am happy with Monistat because it seems to be doing the trick."

7 / 10
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  • Yea...
  • January 14, 2018

For Vaginal Yeast Infection "On day two. First dose, I had mild burning, but that was it. Today, my YI symptoms are gone, but I’m going to continue till it’s done. Second dose doesn’t burn. I did have mild cramping from dose one."

7 / 10
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  • Anonymous
  • October 10, 2017

For Vaginal Yeast Infection "I used the 3-day cream. No burning or itching. I did develop a mild stomach cramp, but that lasted a day and a half."

7 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.