Metoprolol Succinate ER and Depression: What Users Say

• Mag...
• Taken for 2 to 5 years
• May 31, 2019

For High Blood Pressure "I hate this drug. I had been taking 25mg for years along with another blood pressure pill, amlodipine. Worked okay although the metoprolol took me a long time to adjust to. It makes me feel really lousy. The side effects are terrible. Last year I had to have open heart surgery to have my aortic valve replaced. Afterwards, they put me on 100 mg of the metoprolol extended-release. Oh My!! I’ve been on it for 7 months. I might as well be dead. This dosage makes me dizzy, lightheaded, depressed, extremely fatigued, I sleep all day, weight gain, headaches! I took half a pill each day for a few days and actually felt better. I hate this drug. I’m going to tell my cardiologist to lower my dosage way back or I’m just going to stop taking it. I feel worse than I have ever felt in my life. But hey, my BP and pulse are great!"

• Bsh...
• Taken for 6 months to 1 year
• August 16, 2021

For Supraventricular Tachycardia "I can't believe it took me this long to correlate my symptoms with this pill, and I'm a 25-year-old RN. Forty-six years old and have had SVT since my 20s. A couple of years ago, I had a 24-hour stay to evaluate HR of 165. All testing normal. No treatment. A year later, back in the ER with a pulse of 250. I was given Adenosine to convert me and then given Metoprolol Succinate 25mg daily. I've been on it for a year. I noticed some tiredness but nothing major. Over the next year, my tiredness became debilitating, and I suffered severe depression, insomnia, and panic attacks. I didn't make the connection and blamed it on the pandemic and all the isolation and restrictions everywhere. I thought I was just having a hard time. Then the drenching night and day sweats started. Still, I blamed it on perimenopause. But then came the heat and activity intolerance. Minimal activity caused me to become SOB, shake, and be drenched in sweat. Sleep was non-existent. I began having numbness in legs and feet."

• Fre...
• Taken for 1 to 6 months
• July 8, 2018

For Supraventricular Tachycardia "I was diagnosed with moderate/severe obstructive sleep apnea and supraventricular 'events' 4 months ago. I was put on a ResMed PAP machine and Metoprolol Succinate ER 25 mg. I have gained 10 pounds. I feel: no energy, chest heavy, heart pumping weak, breathing decreased/light, affect flat, tired, constipated, I can't think. My events are rare now, but I don't know if my events were due to the sleep apnea and if the PAP helped decrease them because I started both med and PAP at the same time. I miss being extroverted, energetic, and outgoing. I don't know if there is any other treatment available. Ablation? I don't like this med."

• jjo...
• Taken for 1 to 6 months
• April 18, 2019

For Supraventricular Tachycardia "I have only been on Metoprolol Succinate ER for SVT for a few months. I started on 25 mg 2x/day, which was upped to 50 mg 2x/day. The medication keeps my blood pressure in a great range (was borderline high before). So far, I haven't had a reoccurrence of SVT. I did have increased depression, but my thyroid levels were low as well. With regular exercise, the depression seems to have subsided. I gave up all caffeine, which has helped with sleep and anxiety."

• Mee...
• March 11, 2018

For Supraventricular Tachycardia "I have only been taking for 3-4 days and hate it. I have the lowest dose, I'm told. Went to doctors and then E.R. for a second opinion and was told my heart beats are off and racing. Almost 3 years ago, I had an ablation done where they snipped something to stop my rapid heartbeats because I was having them too often. Then this one day, they give me this. It makes me depressed and then at night my whole body hurts. But I'm fine in the morning. I have heartburn as well, so I have to take Tums. Going back to my doctor tomorrow because I don't want to take this anymore. Only taking 25 mg."

• Ann...
• Taken for less than 1 month
• May 17, 2018

For Supraventricular Tachycardia "I've tried to use this drug two separate times, and in less than two weeks, extreme, almost suicidal depression set in, along with fatigue, shortness of breath, and a constant heavy feeling in the chest. It made my diastolic heart failure feel much worse. At night, my heart rate was 45, even when I was wide awake. All this on just a 25 mg starting dose. I had the same reaction to propranolol several years ago. I'll live with the SVT far more comfortably. Quality of life counts!"

• mko...
• Taken for less than 1 month
• April 28, 2022

"Used it in connection with Marfan's syndrome. My dose was 50 mg. My heart rate lowered as intended, and it did help with some anxiety symptoms, which was a nice bonus. However, I became tired all the time, I lost interest in my studies, and it also caused slurred speech. After 2 weeks of usage, the 50 mg dose was not working as effectively in terms of keeping my heart rate down. I did not see any reason to keep going, as raising the dose to 100 mg would have probably destroyed my life. My doctor agreed that the side effects would cause long-term damage, and I'm being put on a different beta-blocker now. The medicine is cheap, and the benefits it had in the beginning were really nice, so I wish that my body didn't react so negatively to Metoprolol."

• Met...
• Taken for 6 months to 1 year
• February 5, 2022

For High Blood Pressure "It got my blood pressure under control with 25 mg metoprolol. I take it with 40 mg propranolol divided 2 times a day. Must say it helped a lot. Had social anxiety, which has been almost gone away. Sure, it takes a few weeks/months to get into it, at the beginning, I felt depressed, tired, erectile dysfunction (which is easily treatable with citrulline/arginine or Viagra) and got low blood sugar. Now, after almost a year, I have mild side effects but are treatable (tiredness). Have tried before: diuretics, ACE inhibitors, calcium channel blockers, and ARBs, and for me, beta blockers are the best since the other medications had far worse side effects. Something I have to add is I might have POTS (self-diagnosed), and maybe it’s why it works so well for me. My pulse gets from 60 to under 100 bpm without these."