Relistor and Cramps: What Users Say

• MRS...
• Taken for less than 1 month
• February 28, 2013

For Constipation, Drug Induced "Follow-up to my previous review on 4/12. I recently began taking the 8 mg injections and have used one every other day for the past 10 days. The pain, nausea, and distension had destroyed my quality of life. I was unable to eat more than a few bites of food at a time. I have had FANTASTIC results with this medicine. It works within 10 minutes or less following injection, causes almost NO side effects except a slight cramping sometimes, so effective I can feel the movement starting right away. I am continuing to use this every other day, to me, this is truly a miracle."

• Sco...
• May 21, 2020

For Opioid-Induced Constipation "I've been on opiates for 20 years and have struggled with constipation. It seems to be getting worse all the time. I drink Milk of Magnesia throughout the day in an effort to produce a bowel movement. I've tried Movantik and Linzess, Dulcolax, Miralax, Senna, and Colace with no luck. Last night I went to the ER because I hadn't pooped in 5 days, and I was in pain. They gave me Relistor, and within 20 minutes I exploded, but it was just brown water and no poop. I had about 5 bowel movements, about every five minutes, but none produced any poop, just water. I also experienced cold sweats and severe cramping and back pain, which passed quickly. I was home in two hours after the injection, and I didn't have any more bowel movements, so my problem wasn't solved. I'm still constipated, and I'm afraid I might be obstructed or impacted. So I guess I'll be headed back to the ER when I can peel myself away from my heating pad and comfy bed. This is miserable!"

• Sil...
• April 9, 2015

For Constipation, Drug Induced "Current pain meds: Fentanyl 50 mcg x 72 hrs & Percocet 10/325 x 4 hrs PRN. Condition: DDD L4-L5 S1 & muscle damage of left shoulder. Past over-the-counter meds: Polyethylene glycol, lactulose, & Amitiza. Relistor experience: Started 2 days ago and was able to have a bowel motion within 30 min with mild cramping & no other side effects. Conclusion: Excellent relief from OIC... 5 stars!!"

• Nie...
• March 8, 2016

For Constipation, Drug Induced "I have been on opioids for 29 years now. About 10 years ago, my doses were so high and the constant pushing because of fecal impaction unless I was taking 10 laxatives at night to wake up with unbearable cramps to have diarrhea, then taking more laxatives throughout the day cured the fecal impaction. But I ended up with an external prolapsed bowel that would come out even going to the bathroom. The doctors had never seen one completely outside, which I would have to manually push back in every time. Surgery was 10 nights in the hospital on one of those automatic beds that move position so you don't get bedsores. 1000+ stitches and staples and now Relistor doesn't always work, but when it does, OMG! It feels like heaven. Yeah!!!!"

• Wou...
• Taken for less than 1 month
• September 19, 2012

For Constipation, Drug Induced "It works! But, and there is a but, the side effects can be pretty intense. Mostly the abdominal cramps and slight headache. It did not work with my first dose but did with my second, approximately two hours after injection. For me, it's definitely worth it because for the first time in months, I went #2 all by myself (meaning no enemas, no suppository!). Amazing, I do stress that if you do use it, make sure you have time to rest and wait. The cramps will stop, you'll have a lot of gas, and then you'll go potty like a normal person."

• Sod...
• February 18, 2011

For Constipation, Drug Induced "I just used Relistor for the first time. I have chronic abdominal pain that provides the wonderful need for strong narcotics. They are terrible on my system and possibly from the constipation or maybe a result of the many, many surgeries I have been through. I have very painful bowel movements. It's like I can feel the stool winding through my bowels, and it feels like sharp rocks! After the injection, I had almost instant cramps and only a moderate amount of gas. I felt the 'winding rocks' moving with a vengeance. That's why I'm not giving this a 10, because of the cramps (which could possibly be issues with my system). Like another reviewer said, I had a massive movement 30 mins later. NICE!"

• Ell...
• June 11, 2016

For Constipation, Drug Induced "The first time I took this, it worked within 5 minutes. I continued to take as directed for the next month. Absolutely nothing. Other than severe cramps, sweating, flushed, sick. I have been on and off of this for over 6 months. It has only worked 1 more time in 6 months."

• cro...
• Taken for less than 1 month
• November 3, 2013

For Constipation, Chronic "My 1st 12 mg injection cramped me severely with sweating & nausea. Got to go about 20 mins later, had been 4 days. Have been on pain meds for 21 yrs and finally found this medicine. Getting ready for 2nd injection, hope the cramping ain't as bad as the first time."

• loc...
• Taken for less than 1 month
• October 2, 2016

For Constipation, Drug Induced "My doctor just put me on Relistor. It's been 6 weeks since I had a small bowel movement. This is my 6th day of 12mg shots, and I've only had one small bowel movement, like a rabbit! Something’s gotta give. I have cramps, nausea, sweating like crazy, severe cramps. I don't know what to do next? Help."

• Glo...
• Taken for 1 to 6 months
• October 23, 2024

For Opioid-Induced Constipation "It actually works! Look, I’ve been on opioids for nearly 13 years due to an accident involving 2 semi trucks. The OIC caused by the opioids is a real issue and can be fatal if not properly addressed. Relistor has made it possible for me to manage it and take more regular BM. The first time I had the shot in my stomach and within 20 minutes, I had bad cramps and gas. I barely made it home and side skirted to the toilet! I pooped weeks of the most awful crap. I could feel it breaking down in my intestines and moving through me. And I went until I had liquid coming out. It completely flushed me. It’s very dangerous for our systems to back up with feces. Don’t allow this to happen. While taking opioids, as this drug is only meant for this, keep regular doses going. Follow directions! Must be 30 mins before a meal. Or it won’t work immediately. Instead, you’ll find yourself waking in the middle of the night on the toilet several times. You won’t go just once. My experience, I go a few times."