Methotrexate for Eczema User Reviews

• geo...
• February 22, 2013

"After suffering from about 5 years old, I'm now 56. Only been on the medication for approx 9 weeks, the improvement has been amazing. I've been unable to cope with the pain and spent many days in bed over the years, so touch wood, this medication will keep on working."

• Scr...
• Taken for 1 to 2 years
• July 23, 2020

"Methotrexate stopped my rashes. I itched, scratched, and bled. I was diagnosed with acute eczema-atopic dermatitis-immune disorder. Because the problem is the skin making too many skin cells, the overabundant new cells try to kick out the older healthy cells. This makes you itch. My itch was uncontrollable with topicals and creams. Methotrexate works by destroying the work of folic acid (needed to build healthy cells). You need to know that a few people may develop lung webbing from methotrexate. You may feel a bit more tired and have more strange BMs a day or two after dosing. It worked for me and is generic and inexpensive. All drugs have side effects."

• Sam...
• February 3, 2021

"I have had severe eczema since I was 16, went through many different treatments and still do. From steroid creams, prednisone, Dupixent, hydroxizine, and doxepin, only steroid creams have worked, however, hydroxizine and doxepin have helped me sleep at night. When I thought all was lost because Dupixent was ineffective for me, my doctor offered methotrexate. I have been on methotrexate for about 20 weeks now. The first 8 or so weeks, I thought it was not working, but around week 10, my skin started getting very clear, no more scaling, cracking, and major peeling. In general, it has made my skin 100 times better. I have dry skin and redness in certain areas, but I apply a steroid cream triamcinolone, and it helps with the skin irritation when it flares up. Methotrexate has been very good for me in general. Many are afraid to take methotrexate because it is a chemo drug and has potentially severe side effects. Dupixent definitely is the thing to try first due to potential side effects of MTX."

• car...
• Taken for 2 to 5 years
• May 15, 2022

"I had sudden flares of severe, head-to-toe dermatitis (assumed to be eczema, biopsy showed lupus, but not my blood) for about 5 years. I was red; my face was especially bad. Methotrexate was advised by my specialist's department head instead of waiting for a drug trial. I am so thankful. It took a few weeks, but the results were extraordinary. When I have to miss a dose (I had a few infections and paused it for vaccines), I have a gradual reoccurrence of rash. I typically take 20 mg/week. I caution users that side effects are disruptive - but not as bad as prednisone. Some weeks, I get hangover-like headaches the day before it is due - frequent enough to notice a trend. I was misinformed and told ibuprofen was fine to use, and Tylenol to avoid, and developed gastritis until I stopped the ibuprofen entirely. I had a liver scan recently because I am at the 5-year mark, and it was all good, and my blood work has been consistently great. My skin is clear except for small patches."

• Ros...
• Taken for 6 months to 1 year
• January 13, 2022

"It cleared my condition extremely well, better than anything I have tried so far. However, I had to stop taking the meds due to the terrible brain fog, depersonalization, depression. It's a shame because aside from those symptoms, I didn't have any other side effects. They took about four months to go away completely."

• Anonymous
• Taken for 6 months to 1 year
• January 15, 2021

"Worked for my skin really well, unfortunately, had to stop because it was making my hair brittle and thinner. It was falling out too much for me to continue taking the medication."