Mepolizumab User Reviews & Ratings (Page 2)

• Maritza
• Taken for 1 to 6 months
• February 6, 2022

Nucala (mepolizumab) for Asthma "I wanted to thank everyone for taking the time to write their experiences. In particular one person wrote about the different asthma medication with same affects. My asthma has been under control while on xolair, Dupixent, forget fasenra, and now Nucala. I’ve had muscle and joint pain with all of them, but this is my third month on Nucala and the muscle and joint pains are worse. I’m having a real hard time with my thumbs, severe pain even when I’m not using my hands. I’ve developed a Bone spur on my left thumb that is extremely painful to the touch. I’m not sure if I now have arthritis. I’m so confused what to do next. I guess I’ll stay on Nucala until it’s obvious beyond any doubt that it is the cause of it all, and I’m unable to manage the pain. Back, neck, spine, hands, muscle spasm on my calves, etc. I forgot to mention my Eosinophils were so high I was hospitalized, another reason why I was switched over to Nucala. I hope some will benefit!"

• TerraCh
• February 15, 2018

Nucala (mepolizumab) for Asthma "I have been on this drug for 8 years. ( It was a clinical trial when I began) I was diagnosed with HES (hypereosinophilia) and it was attacking my lungs the most. Chronic pneumonia/lung infections and asthma. Despite a healthy lifestyle I could no longer walk a flight of stairs or even half a block without being winded and dizzy. Steroid use exacerbated the infections. My dr suggested the mepolizumab clinical trial. The dose was much higher via IV when I started and results were apparent within a week. Main side effect was nausea which has subsided with the lower dose. I now get monthly injections and am perfectly healthy. I work out daily and am very fit. I still have some mild asthma symptoms but rare and easily controlled without prednisone. Haven’t noticed any long term use side effects. I believe this drug saved my life. Downside is cost... Hopefully you have a great drug plan to cover it. But I would definitely recommend trying it!"

• Mary
• Taken for 5 to 10 years
• August 12, 2023

Nucala (mepolizumab) for Chronic Rhinosinusitis With Nasal Polyps "Nucala has been a game changer for me. I suffered from nasal polyps, severe asthma, and sinusitis for 20+ years. I was dependent on prednisone (20 years on a daily basis) and other maintenance and rescue medications. I've had multiple sinus surgeries. After one month of being on Nucala, my polyps cleared and the asthma and sinusitis went away. I have been on Nucala for 5 years now and it is still working wonderfully. This drug is nothing short of miraculous. So grateful for Nucala! I have not experienced any side effects from Nucala. 10+++"

• Straw...
• Taken for 1 to 6 months
• January 10, 2020

Nucala (mepolizumab) for Asthma "I have now had my second injection of Nucala, I was so happy with the results of no runny nose, chest congestion was much better I also have a back problem, and have had one hip replacement surgery and waiting for the second one. I take maintenance medications for pain management. I started with pain so bad, my joint aches, my skin hurt, I was so tired, got exhausted just going to town and trying to get groceries, I stay on my heating pad day and night. I am up and down frequently, my pain meds not working well. I made an appointment to go back to the Dr and see what can be done. I liked the results of the Nucala and what it does for my breathing. Anyone have any ideas?"

• Shelby
• Taken for 1 to 2 years
• January 2, 2024

Nucala (mepolizumab) for Eosinophilic Granulomatosis with Polyangiitis "It took a long time for doctors to figure out what was wrong with me--I had adult-onset asthma that was worsening along with chronic sinusitis. Then, I developed GI issues and was diagnosed with eosinophilic colitis and eosinophilic gastroenteritis. I have been on prednisone for two years. I started Nucala at 100 mg, and it helped immensely but wasn't strong enough to fully resolve everything. So, we recently increased the dosage to 300 mg due to my diagnosis of Churg-Strauss (EGPA), as that is the recommended dose. It is working quite well. My goal is to get off prednisone. I am currently taking 8-10 mg a day. I do not experience too many side effects on Nucala, except for a lot of joint pain. My arthritis has become severe, and I am soon getting surgery on my hand. Overall, Nucala is a miracle drug that has allowed me to feel so much better."

• Duffc
• Taken for 1 to 6 months
• January 24, 2019

Nucala (mepolizumab) for Eosinophilic Granulomatosis with Polyangiitis "I am coming up to my third shot of Nucala. After the first shot I felt normal without any allergy symptoms for the first week, but as the month went on less comfort and more allergies came back. The second month same thing I felt great the first week or so then my sinuses dried out and I started a humidifier which helped with that. The 3rd week I started getting anxiety and it reminded me of the symptoms I had with singular. (Agitated and nervous overwhelming feelings and then it would pass and come back at times when it was warm in the house or where ever I was). I am due for the 3rd shot and they claim it will improve but I am afraid of anxiety coming back. I wish I could figure out if it’s the Nucala causing it but it seems this is only mentioned once in a side effect on here. The shots do seem to help but my asthma was not as serious as some described above. I am on symbicort and xopenex in addition to Nucala"

• Lila
• July 2, 2021

Nucala (mepolizumab) for Asthma "I will definitely start reporting again as the symptoms are the similar to others. It’s definitely making my asthma better but I have side effects of having lower back pains, ear aches, muscle spasms which are real with this injection. Please report your side effects guys, the better data they have gathered from the community the better for the next person."

• 500Sp...
• Taken for less than 1 month
• January 9, 2018

Nucala (mepolizumab) for Asthma "I have been a severe asthmatic for about 45 years. I have been on a steady dose of prednisone and put on tons of weight. I worked for a while then when reducing the dosage I was again in trouble. My specialist finally said lets try Nucala, what a game changer. The second day I felt like a new person, I could go up and down stairs without being winded. I could actually go out and enjoy myself. Our recent weather with sub zero temps what a real test as I usually wheeze terribly. No wheezing. The company that makes the medication is a life saver. Thank You so much for giving me my life back."

• Amber
• Taken for 1 to 6 months
• October 9, 2019

Nucala (mepolizumab) for Eosinophilic Granulomatosis with Polyangiitis "Hi a brilliant drug has helped with the lungs I stop wheezing after first injection I now been on nucula for six months but I have hair loss and severe pain in foot and all over body so painful 24 hours all the time I not sure if it is reducing steroids slowly from 10mg to 5mg over the months or the drug but seem to have all the symptoms everyone is having. It has saved me from my wheezing lungs so I will continue see how I go"

• barney
• Taken for 1 to 6 months
• September 18, 2018

Nucala (mepolizumab) for Asthma "Severe asthma since 14 years old and slowly increasing regular use of steroids, struggling to keep my peak flow over 200. Now I'm 52 and seriously thought I had just months to live. Affecting my family life every day. My eosinophil levels not very high but doctors thought the steroids masked the true level so put me on Nucala. I felt a massive difference within 48hrs . Managed to reduce my steroids down to 7mg by 2nd shot. PF at 400 and stable. It's made a massive difference to our lives and so I write this hoping it will help others. No side effects !"

• Pjb
• Taken for 1 to 6 months
• February 25, 2022

Nucala (mepolizumab) for Hypereosinophilic Syndrome "Just received my 3 shots (300 milligrams) and administered it at home . After working with my doctors. My eosinophils have gone down. But the tiredness, back pain and headaches are horrible. Time will tell if this will be worth it . Totally off prednisone after years of taking it . Unfortunately severe osteoporosis from the prednisone. Age 57"

• severe...
• Taken for less than 1 month
• October 27, 2017

Nucala (mepolizumab) for Asthma "I have severe asthma. Prednisone made me feel better for a little while. I had a severe allergic reaction (anaphylaxis) immediately after receiving Nucala in an infusion center in a hospital. I was transferred to the ER. I was treated and released on high doses of prednisone and benadryl. I had anaphylaxis again (4 days later). An ambulance took me to ER again. I was treated and given an epi pen. I continued to have an allergic reaction for weeks (high doses of prednisone and benadryl.). I wish that I hadn't been allergic to this medication."

• Anonymous
• Taken for 1 to 6 months
• February 27, 2020

Nucala (mepolizumab) for Eosinophilic Granulomatosis with Polyangiitis "I have been getting the Nucala injections for about 6 months now and the first couple of months I could breath ok but developed a sinus/ear infection that caused a complete blockage to my ear. Have still been having to use my nebulizer treatments and rescue inhaler and have severe fatigue, headaches, muscle spasms and back pain. I will not be getting anymore of these injections."

• Rick
• Taken for 1 to 6 months
• May 20, 2023

Nucala (mepolizumab) for Chronic Rhinosinusitis With Nasal Polyps "I am 72 years old and have had stage 3 nasal polyps for 8 years. I just received my second shot of Nucala and have not experienced any side effects from this drug. Before treatment, I would wake up every hour to blow my nose to breathe and prevent mucus from draining onto my pillow. Now, I am able to sleep for up to 2 hours before needing to clear my sinuses, so the drug is definitely moving me in the right direction. If you have concerns about the listed side effects, don't worry. Start taking Nucala and regain control of your life. It's difficult for me to provide a complete rating for the drug since I haven't fully experienced the effects of my second shot, but I would give it a 7 based on the improvement I saw after the first shot. One last thing to note is that the injection process is straightforward and simple. After receiving 2 injections and training at a clinic, you can administer the injections at home and avoid clinic trips if you feel comfortable using an EpiPen to inject yourself."

• Bill
• Taken for 6 months to 1 year
• May 11, 2023

Nucala (mepolizumab) for Chronic Rhinosinusitis With Nasal Polyps "Had nasal polyps and a loss of smell for several years. Started nucala and budesonide rinses at the approximately the same time. Discontinued budesonide and continued on nucala. polyps are better and some smell is back."

• Gmaof
• Taken for 1 to 2 years
• October 8, 2018

Nucala (mepolizumab) for Asthma "Nucala was a life changer for me. My eocinophils were out of control requiring three hospital stays in three months. My doctor prescribed Nucala and for me it was a miracle drug which gave me back my normal active life style. Unfortunately I am not currently getting Nucala injections due to billing errors by a provider and resulting in huge co-pay amounts due from me. I am now in a post Nucala phase until I pay the balance due. Age 70+"

• Veron...
• Taken for 6 months to 1 year
• July 25, 2018

Nucala (mepolizumab) for Asthma "Nucala has turned my life around. I did not expect the immediate relief I experienced after the first injection. I used to get such a build up of mucus in my lungs that I'd have to stop half-way to the bathroom and sit down to cough up a lung. I used to choke on the mucus so badly that sometimes I'd almost blackout. I effortlessly walked the half-mile home after my last injection! I went from going to the ER every 4 to 6 weeks, with 5 hospital stays in a 7 month period, to forgetting to use my nebulizer! I had to get special permission from my employer's insurance to cover this med and it's currently up for review, so I've got my fingers crossed right now. I'm optimistic because it has been so successful. It's not currently approved by the province, but I'm hoping it will be by the time I retire, because I couldn't go back to living without it."

• Anonymous
• Taken for 6 months to 1 year
• December 26, 2020

Nucala (mepolizumab) for Asthma "I have been taking Nucala for 9 months. I have severe persistent Eosinophilic Asthma. My asthma had a rapid onset and began about 2 years ago. I was completely healthy prior. I was using a nebulizer every 2-3 hrs around the clock and on 02 at 3-5L because my airways were so tight. 10 days after the first injection and I was no longer requiring oxygen or neb treatments. Over the course of treatment I've had a few minor set backs but they've been small in comparison to what I was living prior. The first couple of months I had bad headaches and some back aches but both resolved with ibuprofen. I get tired and flu like at times but a short rest usually takes care of that. I have minor skin issues and my hair has thinned a bit but those are things that I'm willing to deal with to have my life back. I can take my grandbaby on walks in her stroller and not be gasping for air. Nucala has been life changing for me."

• Vetas...
• Taken for 1 to 6 months
• August 13, 2020

Nucala (mepolizumab) for Asthma "I just had my 4th Nucala shot.I am not impressed. My severe asthma is still horrible. The shots seem to not help me. My pulmonologist said that I needed to try it through the 4th shot. I got it this morning and had 3 bad asthma attacks since then. I am going to contact my pulmonologist as soon as possible. I am not going to get anymore Nucala shots. Everyone of the shots did absolutely for my severe asthma."

• terri...
• Taken for 1 to 6 months
• April 17, 2023

Nucala (mepolizumab) for Eosinophilic Granulomatosis with Polyangiitis "Where do I start? I was fine until I took Nucala. My PSA immediately doubled, my blood pressure went up, I had debilitating back and shoulder pain, my bowels got clogged up, I was tired, and I had abdominal pain. In short, the stuff was poison to me. All these issues that came up I never had until Nucala. NONE of them. I am no off Nucala but my back still won't heal and is very painful. Be careful what you take and what you believe about these biologics. You could not pay me to take Nucala!!"

• Dare
• Taken for 1 to 6 months
• August 14, 2018

Nucala (mepolizumab) for Asthma "Within 2 hours of my first dose the congestion in my lungs was gone. I still have some minor asthma symptoms but I only have attacks the last week before an injection, and those are mild compared to before."

• Weezy...
• September 19, 2019

Nucala (mepolizumab) for Eosinophilic Granulomatosis with Polyangiitis "Late onset asthma about 18 years ago, polyps, heart valve problems, high eosinphiilis, Periocarditis for over five years. Given Nucala for both severe asthma and Churg Strauss Has helped wheezing and breathing. Have noticed attacks immune and weakest part of body. Constant bladder infections, headaches, sore throats. Am exhausted all the time. In stage Two of disease. Like any other meds helps one thing causes another. Have had nine times, hoping to put disease in remission."

• Weezy
• Taken for 2 to 5 years
• February 5, 2021

Nucala (mepolizumab) for Asthma "I had an allergic reaction to Xolair and have been on Nucala for about 3 years now. I always got headaches felt tired a day or two after I received the injection but today was different. I got the injection Wednesday today is Thursday and when I got home I wasn't feeling good real tired short of breath my heart was racing itchy throat pain in my shoulder and up my neck where I received the shot which I usually feel chest is sore and my oxygen was 92-93. I went to the ER and the doctor told me not to get the injection any more. He did a chest x-ray gave me breathing treatments. The injection really gave me a better quality of life but I am scared to get it again unsure what to do. My pulmonologist is supposed to call me back Saturday and we're supposed to talk about getting the injection again or not. With xolair he said I could die if I get it again so of course I said no I don't want it has anyone else experienced this getting Nucala??"

• n4nw
• Taken for 1 to 2 years
• October 26, 2020

Nucala (mepolizumab) for Asthma "Until I started taking Nacala, my asthma was mostly out of control. Now, in combination with daily high dose cortiosteroides I feel like I have a new set of lungs and have got rid of the elephant that used to feel like it was standing on my chest"

• Scano
• August 23, 2020

Nucala (mepolizumab) for Asthma "I have just started Nucala after being on fasenra for a year (to which I suffered severe side effects) just like what is mentioned in other reviews about Nucala. After reading many reviews I'm not sure about this drug. I had some fatigue and body aches after first injection but not really bad. So I will wait until next injection see how it effects me. Hopefully better than the fasenra."