Lisdexamfetamine for Depression User Reviews

• Thom
• Taken for 1 to 6 months
• May 8, 2021

"I have suffered from Major Depressive Disorder for my entire life. I did TMS and had 17 ECT treatments after trying just about every depression medicine. I changed doctors and we moved to Symbyax at bedtime and Vyvanse upon waking, I have to tell you that Vyvanse has saved my life!! I consider my current doctor to be a genuine innovator and out of the box thinker who recommended Vyvanse to me. I am more than happy to share my story of being alive again. Please don't ever give up. Keep on keeping on!"

• Luvly...
• Taken for 6 months to 1 year
• August 27, 2018

"I have been diagnosed with bipolar severe depression/Anxiety disorder And Despite being on Abilify, Prozac and Xanax. I have spent most of my days in bed; No energy what-so-ever. I have also put on 60 pounds. I asked my Psych if there was a way to break this cycle. He prescribed Vyvanse. I started to notice a difference on 30 mg and then he upped to me 50 mg. I have to say that this medication has really given me this new look out on life. I have more energy now and has given me the ability/ confidence to do things like errands, cooking for my family, interacting with people where as my anxiety prevented me from doing that. I am hoping to return to work one day after being away for 10 years. Its an amazing medication and I am thankful for my psychiatrist. Vyvanse truly does make a difference."

• Lillian
• Taken for 6 months to 1 year
• March 15, 2023

Vyvanse (lisdexamfetamine) "I’ve been taking Vyvanse for treatment-resistant depression for almost a year now. I don’t have ADHD btw. I’ve been on a dozen antidepressants and Vyvanse has outshone them all. I do still take an antidepressant for my anxiety, but my depression is insufficiently treated without the Vyvanse. I haven’t built up a tolerance either. Every aspect of my life is so much better with this med- even my social anxiety and sleep somehow. This was definitely the missing piece. Before the Vyvanse I hardly had the energy to send a text message. Now I work out in the mornings! I only take 20 mg but the difference is night and day. Be sure to use the savings card on the manufacturer’s website even if you have insurance. It can get a little pricey."

• Airti...
• Taken for 1 to 2 years
• May 11, 2021

"I was put on Vyvanse for ADHD, but my doctor had also been trying to control my severe depression as well with different antidepressants. All antidepressants I tried (at least 15) were no greater than a 5 in effectiveness, if rating them. Well, once starting Vyvanse, I noticed a dramatic and positive change in my mood after about a week. I thought that since it helped so quickly, it surely wouldn't be helpful long-term. I was wrong because I have been on Vyvanse for over a year now and I've not grown tolerant to its antidepressant effects nor its effects for my ADHD. Plus, it has fewer side effects than what I experienced with traditional antidepressants."

• Becki
• Taken for 6 months to 1 year
• September 8, 2020

"I've been diagnosed with treatment-resistant major depressive disorder, bipolar II with rapid cycling, PTSD, generalized anxiety disorder, and insomnia. I've been on so many medications over the past 20 years, it's hard to remember them all, but my First day taking Vyvanse - it was like the weight of the world lifted off my shoulders for the first time in my life! I'm currently on 70mg once a day in the morning for the past 6 months. I don't get quite the same effect anymore but it definitely makes me able to get up and stay up throughout the day. I also take ativan 2mg 4x a day to help with the anxiety, but I'm off all the antipsychotics and SNRIs and SSRIs I was on before and am actually able function and feel like a human again."

• ilike...
• April 10, 2021

"This saved my life!! Vyvanse has improved my depression more than every antidepressant I've been on combined. I used to be constantly exhausted, disinterested in everything, and dissociate constantly, just sorta floating thru life. It has given me the ability to do the things that actually make me happy, focus on my schoolwork (I've always had attention issues, but I'm not quite full-blown ADHD), work, and hang out w friends without getting drained. it brings my dissociation down from a constant 7-8/10 to a 3-5, which is huge, and it lasts long enough that I am able to be myself for 100% of the day. I also tried Adderall XR, and it was definitely better than nothing, but made me anxious + didn't last long enough (and just didn't quite work as well). The only thing I will say: Eat something with protein. I hate eating breakfast, but even just yogurt or an egg makes a huge diff in the effectiveness. Side effects are my hands are always cold, but like, whatever because this drug is literally saving my life lol"

• MsUkr...
• Taken for 1 to 6 months
• June 15, 2019

"Everyone is different. Some people like Adderall some people like Vyvanse. For me personally Vyvanse works much better. I was prescribed Adderall at first for my depression. It worked okay but then kind of stopped working. So I switched to Vyvanse. For me it’s much smoother, more natural type of feeling. Gives me energy throughout the day and lasts longer. I would definitely recommend trying it. The only side effect for me is loss of appetite so I have to force myself to eat."

• Anonymous
• Taken for 1 to 6 months
• February 27, 2022

"This medication has saved my life. Even on 3 different antidepressants, my depression wasn’t getting better. Literally after my first dose I noticed a difference. Have energy to live life again. The only side effects I have noticed is my legs have been very restless."

• Vyvanse
• Taken for 1 to 6 months
• July 11, 2022

"I have lived with depression, anxiety for most of my life! I was diagnosed with ADHD 5 months ago. I take Vyvanse, this medication has changed my life! I feel so much better, it's amazing how a tablet can help so much. I feel I can live my life now."

• Kenny...
• Taken for 5 to 10 years
• January 22, 2020

"I've been fighting what is deemed to be depression for years. I've got chronic urinary tract problems and advanced Crohn's disease which is likely the cause or greatly contributes to the cause of the depression, fatigue, etc. Long story short after all the psych docs and all the other meds I've been prescribed Vyvanse is the only medication that keeps me up and going. When I've quit taking it for any amount of time I crash and I crash hard."

• Anonymous
• January 2, 2012

"I was prescribed 20mg of Vyvanse last year after trying different medications for a couple of years without much success. I had found bupropion (Wellbutrin) before after being on SSRIs and felt better immediately after I began taking it. As a result of my mood improving dramatically on more of a stimulant type of medication, and the fact that I smoke cigarettes and drink plenty of coffee, I was prescribed a CNS stimulant to try. My doctor suggested Adderall but I didn't want the up and down mood swings that came with it, so I asked for Vyvanse instead. I moved from 20mg to 30mg a month after I started and haven't looked back. It's a very subtle medication that I find gives me the alertness I need to not feel panicky on a day to day basis."

• Roe
• Taken for less than 1 month
• September 24, 2020

"Much like the previous person, I have depression and extreme fatigue due to Crohn’s Disease. I’ve been on Adderal for a few years and tried Vyvanse too. Today I switched to Vyvanse for good. It’s much subtle and I don’t crash like I do with Adderal. I’m happy my doctor suggested it and my insurance company finally approved it. Good luck to all. Depression can be debilitating for the person suffering and the entire family."

• Toby...
• November 8, 2023

"Lisdexamfetamine has done wonders for my depression. I explained to my doctor that I was feeling kind of sedated and blunt on my antidepressant, so he prescribed me this. Unlike other ADHD medications that can treat off-label depression, the crash is nowhere near as bad as dexamphetamine and Ritalin, and wake promoters like Armodafinil."

• Toby...
• October 24, 2023

"I've finally found the one stimulant that doesn't give me a horrible crash. I don't have ADHD, but I do use lisdexamfetamine off-label for my depression. Honestly, if you're on an antidepressant, add this in conjunction with your treatment. It'll do wonders, one of them being (this isn't the same for everyone) the reduction of anhedonia, which was super bothersome. Feeling emotionally blunt all the time and the second being that it perked my energy levels up, leaving behind the constant feeling of fatigue. Definitely beneficial to have as a depression treatment, however, I wouldn't rely on it as a magic pill. I'd suggest taking it in conjunction with an antidepressant."

• DanDMan
• April 12, 2016

"I suffer from paralyzing anxiety that came on when I was 36 and I'm now 40. I haven't had it for the entire 4 yrs but I'm going theough my 3rd episode now and its brought on by finances and then I suffer a panic attacks which turns into chronic severe bedridden anxiety. I have the thought that just take over and each thought sends me spiraling and then the depression kicks in which makes it worse. I'm a father of 1 and married. Anyway, I was put on Vyvance and its takes it away for the time its in my system. I'm gonna try zoloft to help with the depression after it weres off but vyvance at least gives me a glimmer of hope. I can think clearly so iIhope this is helpful to others"

• Cynthia
• Taken for 1 to 6 months
• November 13, 2022

"I've been dealing with major depressive disorder since I was a child. Some of the medications I've taken, have taken, offer little or no relief. Some, of course, have been better than others. Lisdexamfetamine does however, offer the best relief yet. It allows me to feel like not watching tv all day, and helps me in social situations. Also, I am able to write (I'm a part time writer) with a fresh, clear-headed mind. I am taking 50mgs. but 50mgs twice daily would be ideal. Also, I am grateful when a doctor realizes that major-depressive disorder, is not the same as regular depression. Thank you for your time."

• Tiago
• Taken for 1 to 6 months
• February 11, 2022

"Depression is not exactly sadness, but inability to find pleasure and comfort in things we enjoy in life. I have tried so many meds, and none of them worked the way Elvanse does to me. I highly recommend giving it a try, if other meds for depression haven't helped you yet! The only side effect that I notice from it is increased sweating, and at some point appetite loss."

• AmirA
• May 19, 2023

"Not suitable at least for bipolar depression at all. This one was a letdown, too. It gave me too much sudden mental energy and I just desperately wanted to talk to someone due to the huge urge it gave me. Nobody was in the mood. It actually put me through an intense depressive bipolar disorder. I just made a fool of myself. These medications make so many people having bipolar disorder just overexert themselves and reaching out to anybody for socializing. It doesn't work. In addition, it made me hate food which wasn't good in my case. It made me just a needy person who was in desperate need of talking to others, but others don't care. Just waste of mental energy and money as usual. At the end of the day, I'm more depressed and just worked too much without getting any appreciation from my boss."

• gemit
• Taken for 10 years or more
• May 5, 2023

"35 years of chronic depression, more than a dozen different medications prescribed leaving me even more depressed because of hopelessness and negative side effects. One drug seemed to work but lost its effectiveness after a month, Ritalin. Then a new psychiatrist hearing this about Ritalin prescribed me Vyvanse and from day one to day 5500 (been on it for 15 yrs) I feel normal about an hour after I take it. Life no longer feels like climbing a mountain and my negative thoughts are not totally uncontrollable. I call Vyvanse my miracle drug. It's about to go generic, but even so Shire and now Takeda has a patient assistance program that takes the cost down from $300-$400 to $0. Only problem and it's not a little one, is trying to have doctors prescribe it and pharmacists fill it. As a schedule II drug I have had sooooo much trouble filling it over the years, and these days all it takes is 2 days off it, and I literally get suicidal. Drs do do harm when they keep it from me."

• jm266
• Taken for 5 to 10 years
• April 30, 2024

"Lisdexamfetamine is the only thing I know that helps my depression. It has to do with it being a prodrug that doesn't release the amphetamine until the body metabolizes it and how that affects the dopamine and norepinephrine. During this 'shortage' of stimulant medications, there are times I haven't been able to get it in time. When it runs out, I am essentially immobilized by my depression. I also get very irritable, so my family suffers. I have taken all the other medications, currently Effexor - never, ever get on this, it is literally impossible for me to get off due to the withdrawal symptoms and am stuck with the minimum dose and side effects for the rest of my life - lamotrigine, and trazodone. Again, lisdexamfetamine is the only thing I know for sure helps me."

• Mr Clay
• Taken for less than 1 month
• June 19, 2019

"I’m a 39 year old male who suffers from major depressive disorder and chronic fatigue. Things have gotten so bad that I’m on disability and sleep 12-16 hours a day. My doctor prescribed me this in hopes of it boosting my energy. I took my first 30mg dose this morning. For 3 or 4 hours my heart was beating out of my chest and then I crashed. Not a pleasant experience on day 1 probably won’t take this tomorrow"

• Joni
• Taken for less than 1 month
• April 6, 2024

"I’ve suffered with treatment-resistant depression since I was 30. I'm now 67... Years of trying at least 10 antidepressants, mixed with Abilify and lamotrigine. I was really struggling with getting out of bed, bathing, feeling like a loser because I thought I was lazy. Worried about losing my marriage because I had little to give. I spent most days in my bedroom sleeping. My new doctor of 3 years has been patient with trying different therapies and combinations. He prescribed lisdexamfetamine along with Prozac and lamotrigine. It has helped so much. It doesn’t make me feel crazy, but it gets me out of bed to complete a few tasks a day, even run errands and make scheduled appointments. I'm feeling like I’m actually participating in life. I sleep fine at night. But there is a BIG problem... my insurance is denying coverage for this drug or generic Adderall. It’s expensive on a fixed income. Adderall is cheaper, but I crash at about 2 pm on it. Lisdexamfetamine is smooth."

• TobyP...
• October 29, 2023

"I've been prescribed two stimulants for my depression as an insurance plan to get a little bit of short-term relief from the lack of motivation and low energy to get me out of bed and get going. I was prescribed Dexamphetamine and Ritalin and, unfortunately, to no avail. I was happy for 2-3 hours and then the crash would linger for longer. HOWEVER, Lisdexamphetamine, being a slower release stimulant, has done a very good job for my depression and Anhedonic symptoms. I do get a crash, however, it's not anywhere near as tearful or irritable as the previous two meds. The worst-case scenario is a headache and maybe a little bit of drop in energy, other than that it's great. I've been on this trial for 5 days now, and it's really been mostly positive so far. Definitely recommend giving it a try if fast-release ADHD stimulants aren't working for you."

• Anonymous
• Taken for less than 1 month
• November 19, 2012

Vyvanse (lisdexamfetamine) "I am on my third day of taking this now. First day: mild headache that got worse as the day went on, mild upset stomach, sleeping normal, itchy at night. Second day: bouts of nausea, strange uncomfortable feeling, hot and cold flashes, not a good sleep, itchy at night (worse). Third day: Feel really moody, negative and I have a strange feeling, also exhausted. It clearly isn't for me. I don't feel like "myself" in three days? Kind of scary."

• Depre...
• Taken for 6 months to 1 year
• March 17, 2017

"Taking Vvyanse for treatment resistant depression, started to notice half life extending from 11 hours to 15 hours. Very unusual. The only other med I've taken that has this half life is modavigil, does anyone have similar experiences"