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Linzess User Reviews & Ratings (Page 4)

Linzess has an average rating of 6.6 out of 10 from a total of 870 reviews on Drugs.com. 56% of reviewers reported a positive experience, while 27% reported a negative experience.

Reviews for Linzess

  • RLR
  • Taken for 1 to 6 months
  • May 16, 2024

For Chronic Idiopathic Constipation "I am a 43-year-old female and have dealt with severe chronic constipation issues for a good portion of my life. I have tried everything to the point of losing my mind. I started on Linzess 290 in 2021 and took it exactly as prescribed - in the morning with LOTS of water 30 mins before breakfast. All it ever did was make me bloated & partially work maybe 2 times out of 10, so I quit taking it. Fast forward to March 2024. My symptoms were getting worse, so I saw my gastro dr again and figured I'd give it another shot out of desperation. Took it again as directed for 2 weeks with the same issues as they were in 2021. So I did some reading of reviews and saw others having success taking it at night after eating, so I decided to do the same...this has been a game-changer for me! I take it every other night about 20 minutes after I eat dinner and drink a huge glass of water with it, and the next morning...RELIEF! I feel like a new person! I pray it continues to work like it has been."

10 / 10
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  • JDano
  • Taken for 1 to 2 years
  • August 19, 2019

For Chronic Idiopathic Constipation "I have had horrible constipation issues for years, when I finally went to my gastroenterologist and they put me on Linzess it really did change things. The first few times I took linzess before I went to bed which was a mistake, I won't go into great detail about that but let's just say I had a mess or two to clean up. When I take it like I should it works wonderful, and I'm so thankful that there is something out there that actually works because I have tried everything. This medicine may not be for everyone but it definitely has worked for me the past year-and-a-half."

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  • Thank...
  • Taken for 1 to 2 years
  • June 19, 2019

For Chronic Idiopathic Constipation "I have suffered from constipation all of my life. I’m 44 years old and I would barely have 2 bowel motions (BM) a month. My GI doctor gave me Linzess a year ago and told me to take 145mg twice a day. Omg it worked so good. Now I take only 145mg on a Wednesday and Saturday. This medication was heaven sent. Because it has really helped a lot of people including myself. As far as side effects the only side effects I’ve had was watery stool. That’s why my GI reduced it to 145 mg once a day. But heck I only take it twice a week and I have a BM every other day as long as I take it twice a week. But hey it’s no cramping or painful BM as laxatives always done."

8 / 10
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Frequently asked questions

  • DCG
  • Taken for less than 1 month
  • February 10, 2020

For Irritable Bowel Syndrome with Constipation "I have Gastroparesis / ibs-c so I tried taking Linzess for 10 days. Each day my weight went up another 1/2 pound, my abdomen became more and more swollen and my blood pressure skyrocketed. Been off of it for 2 days now and my BP is still 165/88 (usual for me is 125/70). Resting heart rate is still up 15 points and I am completely swollen with fluid from my head to my feet. Gained 6 pounds of fluid since I have been on it. It only worked on the 1st day and did not work after that. Milk of Magnesia works much better than this drug and is a lot less expensive."

1 / 10
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  • Allie...
  • November 3, 2014

For Chronic Idiopathic Constipation "I've been taking Miralax as I was told to take it daily for my chronic bowel constipation, which always resulted in blockage. I recently saw a commercial for Linzess and decided to research it on my own. I saw my physician, and they let me try it for 30 days, only because of the severity of my blockages, to see a gastroenterologist. I have been on it now for 4 days, and this is the best I've felt in 11 years since my bowel was damaged in surgery by error. I finally feel hope for my physical future."

10 / 10
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Are you taking this medicine?

  • Cathy
  • July 27, 2018

For Chronic Idiopathic Constipation "This medication is a lifesaver! I have had chronic constipation/ IBS my whole life. However, the last two years, I had a health scare that required me to be on high doses of narcotics until I finally had surgery to correct the problem. During this time, I tried stool softeners, senna tea, etc., to help with the constipation, but often times I would need an enema to help. After my surgery, between the increase in all the pain meds prescribed and the surgical pain, going to the bathroom was a nightmare. My surgeon had me on Colace stool softener, Miralax twice a day, and a senna stimulant, but they didn't work. Thankfully, she suggested this medication, and my God do I wish I found this YEARS ago! 2 hours after taking this medication, I felt the urge to go to the bathroom! I actually cried tears of joy to be able to go to the bathroom normally (husband laughed at me - lol). No hurt, no hard stools, no diarrhea, no adverse effects. Thank you, Linzess!"

10 / 10
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  • Doesnt...
  • Taken for 1 to 6 months
  • February 14, 2019

For Chronic Idiopathic Constipation "I feel I need to share my history and reason for treatment with Linzess, as I see many negative reviews here. I have been completely dependent on laxatives for my entire adult life, I’m 44 yrs old. Making me constantly sick. Obviously, this is not sustainable, I was reluctant to try this medication bc other prescriptions have failed me in the past. My gastrointestinal doctor wanted me to at least try Linzess. And I must say, it’s a miracle ! No pain, no cramps, no nausea ! And works like magic ! Yes, you will have diarrhea "

10 / 10
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  • Kaye...
  • Taken for 1 to 6 months
  • September 12, 2019

For Chronic Idiopathic Constipation "I have had chronic constipation for15 plus years its unbearable pain very depressing pain so intent I have passed out with pain from trying to poop. I found linzess about two months ago and I love it. Sometimes it rough due to diarrhea but it worth it to me. The price is unbelievable TO EVER ONE THAT TAKES LINZESS GO TO PRESCRIPTION HOTLINE its for people that can't afford there meds. I thought yeah right $432.00 for linzess they got for me through their manufacturer and I get it for $49.99 a month. That is awesome I can afford to keep taking it they are super about helping you. GOOD LUCK"

10 / 10
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  • Ecgbe...
  • Taken for less than 1 month
  • July 21, 2019

For Chronic Idiopathic Constipation "From viewing many of the comments, it seems that in some cases, this drug was incorrectly prescribed. This drug worked for me as I have a long history of mega-colon and chronic constipation. Even taking Magnesium carbonate (the fizzy kind), I'd have diarrhea that would flow around the extensive compacted stool throughout the large bowel. Also, fiber would only create inflammation in my intestines. Linzess is minimally absorbed which is good as I usually react badly to most modern drugs. I started on the low dose (72mcg) first and then tried the medium (145mcg) dose, which seems better. It took about 2 weeks to eliminate most of the compacted stool, so it may take a while to perceive effective results."

10 / 10
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  • compu...
  • Taken for less than 1 month
  • February 6, 2014

For Chronic Idiopathic Constipation "Tried to get my husband to take this since it came out in January. I was tired of him moping around the house taking laxatives. He has opioid-induced constipation of the worst kind. He finally gave in and tried this and says it is a miracle. It worked within 3 hours and did the job. It also did it smoothly without pain. He will be taking it regularly from now on. He had to pay $30 copay with our insurance."

10 / 10
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101 Report
  • Anonymous
  • Taken for 6 months to 1 year
  • March 5, 2015

For Chronic Idiopathic Constipation "This medicine is everything. I take this and within an hour I'm in the bathroom. Once I take the pill, I drink a whole bottle of water and it helps a whole lot better. I usually go 2-3 times when I take the medicine. This medicine has saved my life."

10 / 10
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  • Ms Tee
  • March 10, 2016

For Chronic Idiopathic Constipation "I have dealt with chronic constipation all my life. No matter how I change my diet, no matter how much I work out to keep things moving, I still get constipated. I can go weeks at a time with no BM and sometimes a whole month. I know this is definitely not normal. My doctor has done 3 colonoscopies and can't seem to find anything wrong. About 3 months ago, I went in with severe constipation and nothing I took helped. He gave me samples of Linzess. I was afraid to take them at first, but I was so miserable I said, 'What the heck, better out than in.' I took the Linzess and within 4 hours I was in the restroom. I still had to do just a little light pushing since the stool that was already in the rectal area was hard as a brick. I love Linzess."

10 / 10
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  • Cindy
  • Taken for 1 to 6 months
  • June 5, 2020

For Chronic Idiopathic Constipation "Have been taking linzess for about 6 months, and it worked great! The my pharmacy quit using Linzess, I was required to get a new prescription for a different drug. Because it worked so well, my doctor give my prescription to a different pharmacy. My insurance now says I don’t “qualify” , and the new prescription is $1600 for 90 days!!! The card from Linzess is not valid because I have insurance! So I guess I will use Ex-Lax because Linzess not available for me!"

1 / 10
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  • jeannie
  • Taken for less than 1 month
  • June 30, 2024

For Chronic Idiopathic Constipation "Reiterating what others have stated: When you start this drug, do it on your day off, or on a day where you do not have anything planned. This is so you will get to know how long it takes to work, and how your body will react to it. Take early in the morning. Wait at least 30 minutes before eating. I take it when I get up, usually 7-8. I run up to DD and get my daily iced coffee. Come home, put coffee in the freezer, take Linzess, and then wait 30 minutes. I then drink my iced coffee. Sometimes I will make some toast. Within 30-60 minutes of drinking coffee, I get the strong urge to use the bathroom. Usually once will do the trick. I strongly recommend you do not do your daily bathing or showering until after the Linzess takes effect. This drug does exactly what my doctor said it would do: cleans you out. No side effects. If I have an appointment or errand in the morning, I skip my dose and take it the next day."

10 / 10
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  • Ron_42
  • Taken for 1 to 6 months
  • March 1, 2014

For Irritable Bowel Syndrome with Constipation "Have suffered from Irritable Bowel Syndrome and Constipation for many years. Have been taking Linzess for 2 months now. I take it every morning 30-60 minutes before I eat, and it works wonderfully! I no longer have to deal with that bloated feeling and belly pain I would feel throughout the day. I also feel that I completely get my stools out, no longer deal with straining on the toilet. Having a bowel movement is now very easy for me and I no longer have to deal with these issues on a regular basis. You do have to take it every day and not skip a dose. You might get loose stools on the first couple of doses when you start Linzess, wasn't a big deal and went away after the first few days. Probably 'loosening' my stools up so I would no longer be constipated."

10 / 10
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  • Arlin...
  • Taken for less than 1 month
  • August 5, 2013

For Chronic Idiopathic Constipation "My doctor said I have chronic constipation. Since laxatives stopped working, fiber supplements, water, fruit, and vegetables don't do anything for me. I had an entire bottle of Magnesium Citrate and it didn't do anything for me. I was so miserable and constipated that I didn't know what to do anymore. My stomach looked like a big balloon and I had gas. My doctor gave me 4 bottles of Linzess 145 mcg/capsule. I took it and it works. I am so happy I found out about Linzess. The first few days, the bowel motion was watery, but now it looks better. It's best to take it early in the morning with a tall glass of water. Within an hour, you will go. I am so happy to know about Linzess and I hope it keeps doing miracles for me. Recommended."

7 / 10
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  • GI nu...
  • February 23, 2015

For Chronic Idiopathic Constipation "I have severe chronic idiopathic constipation. And Linzess usually works within 2-3 hours after taking it. It doesn't work every time, but if it works 2 times a week, then I'm happy. Without it, I only had a bowel motion once a month at the most. And that's after using magnesium citrate."

10 / 10
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  • Keri...
  • June 25, 2013

For Chronic Idiopathic Constipation "I just wrote a note of appreciation to the physician who prescribed LINZESS for me. I have been taking it now for about three months, and it has truly improved my life significantly. After suffering from constant constipation for over thirty years, I am so thankful to have this life-changing medication. It works consistently and predictably every day without any noticeable side-effects. If my schedule does not permit its use, for example having an early flight, I simply do not take it that day. For me, this medicine has been miraculous."

10 / 10
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  • CPano
  • April 16, 2020

For Chronic Idiopathic Constipation "Have had problems with constipation following abdominal surgery. Dr. prescribed Linzess 72 and it worked perfectly right away, with no aftereffects whatsoever. I hope others with constipation problems consider this medication."

9 / 10
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48 Report
  • Hurt
  • Taken for less than 1 month
  • September 20, 2020

For Chronic Idiopathic Constipation "Dr gave me samples (290 mcg dosage) for constipation. Took one pill 6 hrs ago and I have been back and forth to the toilet for the last 2 hrs. The first bowel motion was normal, but every other bowel motion after is all water. I feel a rumbling in my belly and I immediately have to run to the bathroom or it will hit the floor. My anus is on fire! I will never take this again and I don't recommend anyone else should."

1 / 10
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  • Trish
  • Taken for 1 to 2 years
  • September 15, 2020

For Chronic Idiopathic Constipation "I've been on this for over a year, it worked at first then stopped up the dose to 290, same works for a while then stops and I have to use milk magnesia. Can't go out and about unless I wear a depend. You never know when it's going to work."

4 / 10
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  • LIfet...
  • Taken for 1 to 6 months
  • November 22, 2014

For Chronic Idiopathic Constipation "From infancy to my 50s, I've used it all - phenothalein laxatives, castor oil, fiber, Miralax, enemas, bisacodyl, exercise, hydration, Zelnorm while it was available, and on and on. Only the phenothalien/old Ex-lax formula laxatives and Zelnorm were of use. Phenothalien also required drinking 8-16 ounces more fluid when you were already congested, adding painfully to existing distension and then needing to wait up to hours. Since that laxative was removed from the US market in the 2000s, availability now is very limited; Zelnorm was recalled by the FDA for strokes and cardiac issues (and did cause punch-in-the-gut cramping.) Linzess is amazing, reliable, no pain, some diarrhea, but complete control and great increased quality of life!"

10 / 10
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  • Const...
  • Taken for 1 to 2 years
  • August 11, 2019

For Chronic Idiopathic Constipation "Linzess is truly a miracle answer to my prayers. I’m not sure how this voodoo medicine works, but it works!! It has been years of cramping and discomfort until I found Linzess. Rectal fissures requiring surgery, hemorrhoids, etc. I would go 3 weeks without pooping WHILE taking stool softeners. Nothing worked. I could down 3 bottles of Miralax and water, senna tablets, along with some of those magnesium drinks in one sitting and still NOTHING. Linzess is MAGIC. I sometimes get diarrhea from using it, but it dulls the pain so it’s nothing like regular diarrhea. Anyway, if you have chronic constipation and have tried everything (or not), Linzess is for you!!"

10 / 10
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  • MEano
  • April 6, 2021

For Irritable Bowel Syndrome with Constipation "I have IBD with C. I like Linzess. I use it like a laxative once or twice a week in the evenings after work. I can take it around 5 pm and conclude the "trotting back and forth to the bathroom" well before bedtime. The only thing I wonder is will my constitution ever be "normal"?"

10 / 10
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  • Bdani...
  • Taken for less than 1 month
  • July 11, 2014

For Chronic Idiopathic Constipation "I was hospitalized for a week because of a bout with diverticulitis. As a result, my intestines, so I was told, stopped pushing waste through. I was constipated for 3 weeks! My doctor gave me samples of Linzess. It was a miracle! I began having bowel movements on the first day! Some mild diarrhea, but I'm going and there is no cramping, no aches, no bloating. Amazing. I have had constipation issues for years, but not anymore! I highly recommend trying it! Thanks Linzess!"

10 / 10
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84 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.