Linzess Interactions
There are 59 drugs known to interact with Linzess (linaclotide), along with 2 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 10 are moderate, and 49 are minor.
- View all 59 medications that may interact with Linzess
- View Linzess alcohol/food interactions (1)
- View Linzess disease interactions (2)
Most frequently checked interactions
View interaction reports for Linzess (linaclotide) and the medicines listed below.
- albuterol
- amlodipine
- aspirin
- atorvastatin
- baclofen
- bupropion
- cyclobenzaprine
- Cymbalta (duloxetine)
- duloxetine
- famotidine
- gabapentin
- hydroxyzine
- levothyroxine
- lisinopril
- losartan
- Lyrica (pregabalin)
- melatonin
- meloxicam
- metformin
- MiraLAX (polyethylene glycol 3350)
- montelukast
- omeprazole
- ondansetron
- pantoprazole
- prednisone
- tizanidine
- tramadol
- trazodone
- Vitamin B12 (cyanocobalamin)
- Vitamin D3 (cholecalciferol)
Linzess alcohol/food interactions
There is 1 alcohol/food interaction with Linzess (linaclotide).
Linzess disease interactions
There are 2 disease interactions with Linzess (linaclotide) which include:
Report options
QR code containing a link to this page
More about Linzess (linaclotide)
- Linzess consumer information
- Compare alternatives
- Pricing & coupons
- Reviews (885)
- Drug images
- Side effects
- Dosage information
- During pregnancy
- Support group
- FDA approval history
- Drug class: guanylate cyclase-C agonists
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
