Linzess and Upset Stomach: What Users Say (Page 2)

• Ker...
• February 7, 2020

For Chronic Idiopathic Constipation "I had a hysterectomy last week and hadn’t been able to use the restroom (constipated). I’m also on many medications that make me constipated. The doctor gave me the 72 mcg Linzess capsule, and it worked within two hours. It relieved the bloated feeling I had since my surgery. I wouldn’t take this long term though, as it does seem to cause diarrhea. It cleans you out very well. But I needed that. I liked it, as it did not cause cramps, gas, or stomach discomfort with other laxatives or things I’ve taken to relieve constipation."

• Tit...
• Taken for 1 to 6 months
• July 9, 2021

For Irritable Bowel Syndrome with Constipation "Linzess works. It does have a major flaw. It can affect the stomach for hours. It also may upset your stomach and have you running periodically to the bathroom. I'm taking it twice a week to curb unwelcome side effects. My advice is to plan when not to take it in order to enjoy your day."

• Che...
• April 28, 2019

For Chronic Idiopathic Constipation "64 yr old female. When in my 30s, I used Zelnorm. Loved it, but it was taken off the market. In my 40s, I switched to Amitiza. I used it, but it has always given me flu-like symptoms. Body aches, nausea, headache, did not like it. I also found that with all these drugs, you have to start low on whatever dosage works for you, but your body develops a tolerance for it over time and you need to up the dosage. I was having to take more Amitiza, making me feel sicker. When Linzess came out in my mid 50s, it worked for me and it does not make me sick. But over time, I have noticed increased bloating, puffiness, weight gain, and joint pain. Hate that! All of them caused diarrhea. I take mine when I go to bed, maybe around 11:00, and begin to feel stomach cramps about 3-4:00 in the morning. I get up and go, then sleep a couple of hours until 6:00 when I get up for work. I don’t get great sleep that night, but it’s better than being at work and going, and going. I take 2 highest doses every 2-3 days."

• Csm...
• Taken for less than 1 month
• January 25, 2020

For Chronic Idiopathic Constipation "I take pain meds that cause constipation. I've tried OTC for years, but nothing helped without extra issues. My neurologist gave me samples of Linzess to try. I took a 72 mcg capsule this morning and had a BM within 2 hours. Since then, I'm having the gurgly stomach noises and some discomfort. I realize I've literally taken 'one'... But, I'm commenting because it seems like every person has very different experiences. I've never seen such inconsistencies with a drug as far as reviews!? Between this and my symptoms, I'm reluctant to continue..."

• MsJ...
• Taken for less than 1 month
• June 20, 2014

"I have been diagnosed with small bowel bacterial overgrowth. I had eaten at a restaurant last September and had gotten very sick from the food, and have had stomach problems since then: bloating and constipation. The GI prescribed me Linzess a few days ago. I took the first one yesterday, and a few hours later, I had such horrible, severe diarrhea. My stomach cramped most of the day, and I was pretty nauseated to where all I felt comfortable eating was toast and Cream of Wheat. Just took my second one; I will see if that was a one-time effect or if it'll happen again. If it does, I will not take any more, as the diarrhea was so, so severe that I'd rather put up with the bloating and constipation than the severe diarrhea."

• Ser...
• Taken for 1 to 6 months
• August 31, 2021

For Chronic Idiopathic Constipation "I have been taking this med at 145 mg for about two months. It does work, but it's very harsh. Within three hours of taking it, I'll have an intense bout or two of diarrhea that wrings me out completely. A few days of this in a row leaves me feeling fatigued, so I alternate: two days with Linzess, two days without. Side effects include feeling very bloated and a weird stomach ache that I can only describe as a raw, torn-up feeling. I've also had a few accidents, especially in the first week of taking. What a mess. So altogether, it's not ideal, but it's better than never going to the bathroom at all."

• Kat...
• Taken for less than 1 month
• May 23, 2018

For Irritable Bowel Syndrome with Constipation "My doctor gave me samples of Linzess to try. I have IBS (Irritable Bowel Syndrome), she says. But I am not constipated. I told her that. Two days of taking the lowest dose at 8 a.m. produced seven hours of watery diarrhea and stomach cramping and backache for over five hours. At this rate, I will have dehydration and malnutrition. I am a 66-year-old female with a diagnosis of gastritis and esophagitis. I just called her office to report my results. I had a colonoscopy, and this one pill did more than my prep!"

• Jam...
• Taken for 1 to 6 months
• January 4, 2022

For Chronic Idiopathic Constipation "I was prescribed Linzess after being backed up for more than 3 weeks. A trip to the ER and what felt like an exorcism of my colon later, the GI gave me this. The first couple of days taking it, my stomach cramping was still happening, and I had a lot of discomfort. Taking it regularly produces bowel movements on a regular basis. Once I was going every couple of days, I stopped taking it and started getting backed up again. Took it with the hopes of it working later in the evening, but it worked within an hour or two, and I was racing for the toilet at a family gathering."

• Hug...
• April 6, 2016

For Irritable Bowel Syndrome with Constipation "I took one pill that gave me a terrible stomach ache that lasted three days."

• Kin...
• December 2, 2016

For Chronic Idiopathic Constipation "I bled from my rectum after using this medicine. I had stomach cramps as well. I recommend that you never use this medicine unless you want to be in severe pain."

• Ric...
• Taken for less than 1 month
• August 27, 2019

For Chronic Idiopathic Constipation "I was given a sample of the lowest dose Linzess to try this morning and developed severe cramping, followed by the runs and stomach rumbling. I had to use both Pepto as well as Imodium to help me."

• Mka...
• February 1, 2018

For Chronic Idiopathic Constipation "Tried this for my chronic idiopathic constipation (CIC), but it caused bloating, and my stomach felt upset. Had to stop, will try something else."