Skip to main content

Linzess for Chronic Idiopathic Constipation User Reviews (Page 5)

Reviews for Linzess

Commonly mentioned side effects
  • Anonymous
  • Taken for less than 1 month
  • June 22, 2014

"I have been constipated for over 20 years. Recently, I started having stomach pains. After one week of discomfort, I went to the ER. They took a flat plate x-ray and concluded that I should see my doctor right away. The doctor prescribed Linzess 145 mcg. He gave me samples for 16 days and a prescription to fill. After taking 1/day for 6 days, I called the doctor, and he instructed me to take 2 (290 mcg). It worked like a miracle, so I took it for 2 days and went back to taking 1/day, and this time with the same results, like when I took 2 caps. This is amazing and without any side effects. But I am unable to purchase it because it is too expensive."

8 / 10
Was this helpful?YesNo
72 Report
  • Hur...
  • Taken for less than 1 month
  • September 20, 2020

"Dr. gave me samples (290 mcg dosage) for constipation. Took one pill 6 hrs ago, and I have been back and forth to the toilet for the last 2 hrs. The first bowel motion was normal, but every other bowel motion after is all water. I feel a rumbling in my belly, and I immediately have to run to the bathroom, or it will hit the floor. My anus is on fire! I will never take this again, and I don't recommend anyone else should."

1 / 10
Was this helpful?YesNo
44 Report
  • Kim...
  • January 19, 2016

"I'm a 45-year-old extremely fit woman who eats extremely healthy, but has suffered with IBS-C for 25 years. I used to take Bentyl when I would have IBS attacks, but I kept needing more and more, which would continue to constipate me. Welcome Linzess! After getting the dosing and timing right, it's been a LIFESAVER! I take the lower dose before bed and have 4-5 loose BMs in the morning, which cleans out my system. I have not had a single IBS attack in MONTHS since I started Linzess. Yes, it's a pain in the bottom, but I'd rather have 4-5 loose stools in the morning than live with constant constipation. The days I don't take it at night, I don't go to the bathroom in the morning. Relief...finally!"

7 / 10
Was this helpful?YesNo
63 Report

Frequently asked questions

  • Bet...
  • June 28, 2014

"I have had constipation problems for years. Before Linzess, I was taking up to 6 different medications to try to go, and then it would hit with a vengeance and last all day long. I couldn't work a full-time job because of it. I was miserable all the time with bloating, cramping, and nausea. I have only been on it for a week, and I already feel so much better. I now have bowel movements like normal people. Yes, there is some diarrhea, but I think I am still getting used to it. If the diarrhea gets bad, I will cut back to every other day. But, I will talk to my doctor first."

8 / 10
Was this helpful?YesNo
71 Report
  • LJa...
  • March 19, 2014

"I began taking medication for my thyroid about a year ago. Prior to that, I NEVER had issues with constipation. I was an 'at least once-a-day goer' and happy about it. The various medications I started REALLY messed me up. I would go DAYS without a bowel movement and I FELT TERRIBLE. I was not made for this. I tried every over-the-counter medication, both natural and not, that you can imagine. Nothing would work. About 40 days ago, my doctor prescribed me Linzess, and I have gone *almost* every day since. It is almost ALWAYS loose stool, however, I sometimes even have to run to the restroom. But I will take that over constipation ANY day. One other drawback is that my stomach is VERY loud when I'm on it. Quiet rooms and quiet meetings..."

8 / 10
Was this helpful?YesNo
77 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
  • Gid...
  • December 17, 2019

"Neurological side effects: I'm taking Linzess 290 for more than 2 years. I suffered years from constipation, and Linzess solved the problem like a kind of miracle. The problem started a few months ago. I started to feel a 'pins and needles' feeling. (The professional name is paresthesia.) It started with the limbs and later all over the body. I went to a few doctors: neurologist, orthopedist. I did many checks (blood, EMG, etc.), and all the results were normal. At the beginning, no one connected it to Linzess because it's not one of the known side effects, but then one of the doctors suggested I stop taking Linzess for a few days. After 2-3 days, all the neurological symptoms disappeared! Now I'm taking Linzess 145. It solved the neurological problem, but then I suffered a little bit from constipation, so my doctor suggested I add lactulose, and now it's okay."

8 / 10
Was this helpful?YesNo
42 Report
  • Mar...
  • November 6, 2013

"After trying everything under the sun...nothing ever worked. Not to go into a long drawn-out story...tried Linzess 145, didn't work...tried the Linzess 290, got results within hours all that day. I am very happy with it. I've done colonics, all kinds of laxatives, detoxes, enemas, etc. The best thing in my life right now is LINZESS."

10 / 10
Was this helpful?YesNo
71 Report
  • yol...
  • August 2, 2013

"I have been on long-term/long-acting narcotics which have made me very constipated. I was going once every 3-4 weeks, and when I did go, it was hard and caused a lot of bleeding. I have tried everything imaginable: enemas, suppositories, laxatives, and stool softeners, to no avail. I asked my GI doctor for this or Amitiza and was told that these were only available for IBS-C. He told me to do things I was already doing (drink plenty of water, eat leafy green veggies, and take stool softeners). My primary care doctor (who is a saint) said let's try it anyway, and it worked! I only go 2-3 times per week, but it is so good to know that I have some semblance of regularity now."

10 / 10
Was this helpful?YesNo
73 Report
  • Lov...
  • Taken for 6 months to 1 year
  • July 17, 2017

"Holy hell! I suffer from chronic constipation, IBS, and I have diverticulosis. I tried fiber products that you mix with water, chia seeds, every laxative, and nothing worked 'right.' Laxatives gave me cramps, and fiber gave me bloat. I took Linzess 145 mcg, and 30 minutes later I literally exploded at least 8 times. Over a month, I took it 2-3 times a week, couldn't handle daily. But I did lose pounds, from 142 to 128. It has helped me so much, I love it! I've always been thin, but my gut was growing. Problem solved. No more constipation! Highly recommend it, but stay close to a toilet."

10 / 10
Was this helpful?YesNo
57 Report
  • Fli...
  • Taken for 1 to 6 months
  • January 17, 2015

"I have suffered for a year with severe gastro problems that landed me in the emergency room three times and a ride in the ambulance. This medicine is a miracle but can cause severe diarrhea (like stay close to the bathroom and don't leave your house till you adjust). It is a miracle medication and has greatly improved the quality of my life."

9 / 10
Was this helpful?YesNo
66 Report
  • LNC...
  • Taken for less than 1 month
  • July 14, 2019

"I had my gallbladder taken out 19 years ago. For the first 5 years, I had chronic diarrhea, never diagnosed with IBS, but then it went completely opposite and I started having chronic constipation for the last 14 years. I have been on this medication for 2 weeks, and it is amazing! I normally can’t go to the bathroom except for maybe once a week, if not once every 2 weeks, even after using magnesium citrate! Now I go once, if not twice a day, and feel so much better. I highly recommend this medication!"

10 / 10
Was this helpful?YesNo
41 Report
  • Ava...
  • April 1, 2015

"I have been taking this for a little over a month, and I am extremely happy. I have suffered from chronic constipation my entire life. Since being on this medication, I have regular bowel movements and less cramping and bloating. It does make me drowsy, so I now take it before I go to bed. I take one at night, and by the morning, I am able to go."

9 / 10
Was this helpful?YesNo
67 Report
  • KAR...
  • October 9, 2014

"Linzess is a wonderful medicine. It provides optimal relief of chronic constipation within hours of ingesting it, without any cramping that I have experienced with similar medicines and over-the-counter laxatives!"

10 / 10
Was this helpful?YesNo
67 Report
  • DEE...
  • May 19, 2014

"I started Linzess and within about 5 days, it worked for me. Actually, I got very loose bowels, but it was working. Within a couple more days, I felt sick, very weak and tired. I almost felt like I was drugged and could feel my head moving back and forth. This happened for two days. I stopped it for a day or two and was fine. I took it again, and the same thing happened. I had to get in bed and sleep it off. Tired, felt weird. I stopped taking it."

2 / 10
Was this helpful?YesNo
74 Report
  • Ipo...
  • Taken for 1 to 6 months
  • May 20, 2016

"This is a life-changing, amazing medication. I found that it works best for me if I do not eat past 6 pm and then take the pill before bed around 9 or 10 pm. Then I go to the bathroom in the morning 2-3 times before work, and I have never felt better. I have too much energy now and a flatter, not bloated, painful stomach! I know it does not work for everyone, but it worked for me, and if you have issues, you should try this for sure. I had to play with the time I took it for a while, but now that I have it dialed in, I hope I never have to live without it!"

10 / 10
Was this helpful?YesNo
58 Report
  • Lim...
  • October 11, 2013

"This has been a miracle for me. I had a bowel prep for a colonoscopy and endoscopy which cleared my system. My doctor started me on 290mcg of Linzess the day after the procedure. I have gone to the bathroom every day since, sometimes more than once. I have little or no reactions to the medicine other than when I need to go, I need to go now. I keep it by my bed and take it with a glass of water first thing in the morning. No more bloating or gassiness. Cost is the only drawback. Expensive if you do not have insurance. I have suffered with chronic painful constipation for about thirty years."

10 / 10
Was this helpful?YesNo
69 Report
  • Gra...
  • March 29, 2017

"I am 68 years old and a recently retired registered nurse. I have had problems off and on with irregularity most of my adult life. I used OTC laxatives sporadically and ate a lot of roughage. Six months ago, I had a minimally invasive mitral valve repair, followed by a heart attack and stroke six days post-op, and an emergency cardiac stent. I had been prescribed Ativan for anxiety and Tramadol for pain, as well as Amiodarone. All of these contributed to chronic constipation. A few months back, I thought I was having a bowel obstruction. My primary physician recently prescribed Linzess. Within hours, I experienced a bowel movement without straining for the first time in six months. It was the best day I've had since last August."

10 / 10
Was this helpful?YesNo
54 Report
  • Sup...
  • Taken for 2 to 5 years
  • December 19, 2015

"I have had a sluggish bowel with incomplete emptying on a daily basis. I was always full, bloated, and miserable. Since taking 145 mg of Linzess in the morning, I empty 100% and feel great every day. It has changed my life, it's a miracle drug for me."

10 / 10
Was this helpful?YesNo
60 Report
  • loi...
  • Taken for less than 1 month
  • March 27, 2015

"I have had severe constipation all my life. I was taking over-the-counter laxatives daily to go to the bathroom, so I decided to talk to my doctor about a prescription laxative. She gave me Linzess. Well, I have been on Linzess for a week now. Mornings are such a breeze. I take Linzess 145 mg a half hour before meals and have an elimination within 2 hours or less. This medicine is a miracle for me."

10 / 10
Was this helpful?YesNo
63 Report
  • Ano...
  • April 6, 2015

"I have had chronic constipation for most of my life. I have had to take a laxative on a weekly basis to be able to go once a week. My doctor gave me this at my request, and I have to say it has been a lifesaver. I now am able to go every day. I have some discomfort in my abdomen that lasts for a couple of hours, but it is minimal and certainly nothing like the discomfort of being blocked up. I am so very pleased and hope it continues to work. I would highly recommend this drug!"

10 / 10
Was this helpful?YesNo
60 Report
  • DC2...
  • January 4, 2015

"I was prescribed Linzess for chronic constipation. Within 6 days, I gained 7 pounds. When you're only 120 pounds, 7 is great! I'm an extremely active person and a healthy eater. I thought it was water weight from the medicine, but I've been off the medicine for over a week and still weigh the same. Wish I had seen all the posts online about rapid and stubborn weight gain prior to taking it!"

5 / 10
Was this helpful?YesNo
77 Report
  • Byp...
  • Taken for 1 to 6 months
  • May 31, 2016

"This works great, however, the side effects are less appealing. You cannot trust a fart on this, ever! I take it first thing in the AM on an empty stomach, and you better not leave the house within an hour because exactly one hour later, hot lava explodes. Ugh. But the constipation is gone! Be sure to have a huge supply of fresh underwear when you take this!"

8 / 10
Was this helpful?YesNo
56 Report
  • SBa...
  • Taken for 1 to 6 months
  • May 19, 2019

"I have suffered for years with chronic constipation, literally, it would be weeks of not being able to properly go. I finally heard about Linzess and asked my doctor about it, and he said it was worth a try. I was so hopeful that I might finally find relief. Well, it worked for approximately 2 weeks, and then all of a sudden, nothing. I’m on the 145 mg dosage, but after reading so many reviews from others, I’m highly doubtful that the 290 mg will work for long term. I’m sick of hearing the same blah blah from the doctors: “drink more water, exercise, eat bulk fiber foods.” I do all that, I drink plenty of water, run three miles a day, and eat more roughage than my horse, and I’m still constipated. I wish that there was something out there that would “fix” this problem that so many people suffer from."

2 / 10
Was this helpful?YesNo
41 Report
  • Por...
  • April 30, 2019

"I've been using Linzess for about 6 months and wanted to share how I made the medicine work for me. I tried taking it in the morning like the directions say but couldn't handle the gas and bloated stomach for several hours after. I decided to try taking it before bed instead, and it's been so much better! I now have a bowel movement about 30 minutes after I wake up and none of the side effects. I also highly recommend taking it for several weeks before you give up because it takes some time to adjust, and then I had hardly any side effects. I started on the 145 mg dose, which worked for a little while but stopped, so now I'm on 290 mg, and it's working great."

8 / 10
Was this helpful?YesNo
40 Report
  • Vea...
  • Taken for less than 1 month
  • July 16, 2016

"This medication has been great thus far. I have had severe constipation my entire life. I was so desperate for help, with teas and other laxatives not working, the doctor gave me this Rx. I have not had the severe cramping that others have had at all. I take it in the morning on an empty stomach, eat a meal about 1/2 hour later. It produces a bowel movement for me, which is complete or feels complete in about 30 minutes; stools are soft, no straining, and most of all I don't fear going to the bathroom. I have had, on occasion, two or three follow-up BMs, nothing major, and they are quite small. I will start cutting back the medication from every day to every other day or so and see what happens, but right now this medication is a huge relief."

10 / 10
Was this helpful?YesNo
54 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.

Learn more about Chronic Idiopathic Constipation

Care guides