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Linaclotide for Chronic Idiopathic Constipation User Reviews (Page 3)

Brand names: Linzess

Linaclotide has an average rating of 6.6 out of 10 from a total of 563 reviews for the treatment of Chronic Idiopathic Constipation. 56% of reviewers reported a positive experience, while 26% reported a negative experience.

Reviews for Linaclotide

  • Happy...
  • Taken for 2 to 5 years
  • June 12, 2019

Linzess (linaclotide) "I have been taking Linzess for over four years now. Started at 145 every morning 1/2 hour prior to first meal. At some point during the day, I would develop diarrhea at unpredictable times. Started taking it right before bedtime, and the next day would start with diarrhea again, but at least it would be done by 10 o’clock in the morning. Better! Then the 72 dose became available. Started with that dose right before bedtime. TaDa!!! Seven mornings a week with my first cup of coffee! Linzess has been a lifesaver for me! I believe if you experiment a bit to find the right dose and time of day ~ Linzess can work for anybody! No side effects except those experienced during my trial and error period, which was about three months. Stick with it until you find what is right for you. Highly recommend!"

9 / 10
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  • Cant...
  • Taken for 1 to 6 months
  • January 13, 2014

Linzess (linaclotide) "I'm 36 years old. I've battled with constipation for as long as I can remember. It got so bad I was taking a pill laxative once weekly routinely, which, as you know, was painful. I got Linzess 290 samples from my doctor. I took it at 4 p.m. In less than 2 hours, I felt my stomach rumble as if I may have diarrhea. Thank goodness I was near a bathroom. Anyway, it cleared me out, no pain. I take it when I want to go. It works, just be near a bathroom. I swear I can't live without it now. Being constipated is far worse than diarrhea any day, in my opinion!"

10 / 10
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  • KKano
  • Taken for less than 1 month
  • January 5, 2020

Linzess (linaclotide) "Began Linzess last month after years of constipation. started on 145 dose and had no effect at all. Dr increases to 290. Still no effect other than some gas. However, when coupled with Metamucil 2x per day and Miralax 1x day, I have decent BMs at least every other day. No diarrhea or bloating. Took all 3 meds for me...nothing effective on its own."

8 / 10
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  • Stacart
  • Taken for 1 to 6 months
  • May 2, 2017

Linzess (linaclotide) "I am a 40+ female. I thought I was going to live in misery the rest of my life. I had bowel movements every 3-5 days. I had so much bloating. I was cranky and had very little energy. I had constant pain in my back under my ribs. Since taking Linzess, all of that is gone and I have had a bowel movement every day. My energy is so much better. I am a different person. Thankful to God!"

9 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • March 28, 2013

Linzess (linaclotide) "I have suffered from Gastroparesis for about 6 years now. This is a disease where your stomach and intestines are paralyzed. It is EXTREMELY painful!! Severe constipation is a MAJOR factor when you have this disease. Recently, I went to the ER with terrible gut pain, and my entire abdomen was distended to the point of looking like I was 8-9 months pregnant! I had not had a bowel movement for 6-8 weeks, but when I told the doctor on-call this, after waiting to see him for 5.5 hours, he laughed and told me 'it isn't possible to go that long without having a bowel movement!'. I then went to see a different doctor at a different clinic. He gave me samples of Linzess, and I FINALLY WENT! Just wish ALL doctors knew about this medicine!"

10 / 10
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  • IBS-c
  • Taken for 1 to 6 months
  • October 17, 2014

Linzess (linaclotide) "Best stuff to help with irritable bowel syndrome! I take it every day and have noticed the diarrhea subside and have 'regular' bowel movements after two weeks. If you take it each day and not 'as needed,' you'll notice a huge difference."

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  • KhyliJ
  • Taken for 1 to 6 months
  • February 25, 2020

Linzess (linaclotide) "I have been diagnosed with CIC. I was 'normal' until after a hysterectomy a year ago. I didn't have a BM for 15 days after surgery and rarely have gone on my own since. I have to use enemas, suppositories, mag citrate etc to force a BM. If I take the 'wait and see' approach, I simply don't go. At all. I tried Amitiza and it did nothing but make me so nauseous and headaches that I couldn't function. Switched me to Linzess. I started on 72mcg dose for 2 weeks and except for a few noticeable tummy gurgles, it did not work. Two weeks later I had to use mag citrate and an enema to get things flushed out. Dr upped the dose to 144mcg daily. It's been a full week and nothing but insane bloating and nausea. I have had every test under the sun and it all comes back normal. But this med has not worked either."

1 / 10
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  • Mom_i...
  • Taken for 1 to 2 years
  • June 29, 2016

Linzess (linaclotide) "I have been using Linzess or Constella as it's known in Canada for over a year. It has been 100% a miracle for me and my life. I have played around with it and I wanted to share with everyone what I found. 1. I take this every 2 or 3 days and completely clear out. 2. The days I take it, I set my alarm to wake me up at approximately 4 or 5 am and take my dose along with 1 liter of water and go back to sleep. By the time I get up, I'm ready to empty. 3. You have to take it with more than a glass of water. One liter has worked best for me. Being dehydrated or not drinking enough water stops it from working as well since it's an osmotic (pulls water to the bowel). 4. Be aware you will have loose stool for the day. I will take it any day over constipation!!!"

9 / 10
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  • RLR
  • Taken for 1 to 6 months
  • May 16, 2024

Linzess (linaclotide) "I am a 43-year-old female and have dealt with severe chronic constipation issues for a good portion of my life. I have tried everything to the point of losing my mind. I started on Linzess 290 in 2021 and took it exactly as prescribed - in the morning with LOTS of water 30 mins before breakfast. All it ever did was make me bloated & partially work maybe 2 times out of 10, so I quit taking it. Fast forward to March 2024. My symptoms were getting worse, so I saw my gastro dr again and figured I'd give it another shot out of desperation. Took it again as directed for 2 weeks with the same issues as they were in 2021. So I did some reading of reviews and saw others having success taking it at night after eating, so I decided to do the same...this has been a game-changer for me! I take it every other night about 20 minutes after I eat dinner and drink a huge glass of water with it, and the next morning...RELIEF! I feel like a new person! I pray it continues to work like it has been."

10 / 10
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  • JDano
  • Taken for 1 to 2 years
  • August 19, 2019

Linzess (linaclotide) "I have had horrible constipation issues for years, when I finally went to my gastroenterologist and they put me on Linzess it really did change things. The first few times I took linzess before I went to bed which was a mistake, I won't go into great detail about that but let's just say I had a mess or two to clean up. When I take it like I should it works wonderful, and I'm so thankful that there is something out there that actually works because I have tried everything. This medicine may not be for everyone but it definitely has worked for me the past year-and-a-half."

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  • Thank...
  • Taken for 1 to 2 years
  • June 19, 2019

Linzess (linaclotide) "I have suffered from constipation all of my life. I’m 44 years old and I would barely have 2 bowel motions (BM) a month. My GI doctor gave me Linzess a year ago and told me to take 145mg twice a day. Omg it worked so good. Now I take only 145mg on a Wednesday and Saturday. This medication was heaven sent. Because it has really helped a lot of people including myself. As far as side effects the only side effects I’ve had was watery stool. That’s why my GI reduced it to 145 mg once a day. But heck I only take it twice a week and I have a BM every other day as long as I take it twice a week. But hey it’s no cramping or painful BM as laxatives always done."

8 / 10
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  • Allie...
  • November 3, 2014

Linzess (linaclotide) "I've been taking Miralax as I was told to take it daily for my chronic bowel constipation, which always resulted in blockage. I recently saw a commercial for Linzess and decided to research it on my own. I saw my physician, and they let me try it for 30 days, only because of the severity of my blockages, to see a gastroenterologist. I have been on it now for 4 days, and this is the best I've felt in 11 years since my bowel was damaged in surgery by error. I finally feel hope for my physical future."

10 / 10
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  • Cathy
  • July 27, 2018

Linzess (linaclotide) "This medication is a lifesaver! I have had chronic constipation/ IBS my whole life. However, the last two years, I had a health scare that required me to be on high doses of narcotics until I finally had surgery to correct the problem. During this time, I tried stool softeners, senna tea, etc., to help with the constipation, but often times I would need an enema to help. After my surgery, between the increase in all the pain meds prescribed and the surgical pain, going to the bathroom was a nightmare. My surgeon had me on Colace stool softener, Miralax twice a day, and a senna stimulant, but they didn't work. Thankfully, she suggested this medication, and my God do I wish I found this YEARS ago! 2 hours after taking this medication, I felt the urge to go to the bathroom! I actually cried tears of joy to be able to go to the bathroom normally (husband laughed at me - lol). No hurt, no hard stools, no diarrhea, no adverse effects. Thank you, Linzess!"

10 / 10
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  • Doesnt...
  • Taken for 1 to 6 months
  • February 14, 2019

Linzess (linaclotide) "I feel I need to share my history and reason for treatment with Linzess, as I see many negative reviews here. I have been completely dependent on laxatives for my entire adult life, I’m 44 yrs old. Making me constantly sick. Obviously, this is not sustainable, I was reluctant to try this medication bc other prescriptions have failed me in the past. My gastrointestinal doctor wanted me to at least try Linzess. And I must say, it’s a miracle ! No pain, no cramps, no nausea ! And works like magic ! Yes, you will have diarrhea "

10 / 10
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  • Kaye...
  • Taken for 1 to 6 months
  • September 12, 2019

Linzess (linaclotide) "I have had chronic constipation for15 plus years its unbearable pain very depressing pain so intent I have passed out with pain from trying to poop. I found linzess about two months ago and I love it. Sometimes it rough due to diarrhea but it worth it to me. The price is unbelievable TO EVER ONE THAT TAKES LINZESS GO TO PRESCRIPTION HOTLINE its for people that can't afford there meds. I thought yeah right $432.00 for linzess they got for me through their manufacturer and I get it for $49.99 a month. That is awesome I can afford to keep taking it they are super about helping you. GOOD LUCK"

10 / 10
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  • Ecgbe...
  • Taken for less than 1 month
  • July 21, 2019

Linzess (linaclotide) "From viewing many of the comments, it seems that in some cases, this drug was incorrectly prescribed. This drug worked for me as I have a long history of mega-colon and chronic constipation. Even taking Magnesium carbonate (the fizzy kind), I'd have diarrhea that would flow around the extensive compacted stool throughout the large bowel. Also, fiber would only create inflammation in my intestines. Linzess is minimally absorbed which is good as I usually react badly to most modern drugs. I started on the low dose (72mcg) first and then tried the medium (145mcg) dose, which seems better. It took about 2 weeks to eliminate most of the compacted stool, so it may take a while to perceive effective results."

10 / 10
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  • compu...
  • Taken for less than 1 month
  • February 6, 2014

Linzess (linaclotide) "Tried to get my husband to take this since it came out in January. I was tired of him moping around the house taking laxatives. He has opioid-induced constipation of the worst kind. He finally gave in and tried this and says it is a miracle. It worked within 3 hours and did the job. It also did it smoothly without pain. He will be taking it regularly from now on. He had to pay $30 copay with our insurance."

10 / 10
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  • Anonymous
  • Taken for 6 months to 1 year
  • March 5, 2015

Linzess (linaclotide) "This medicine is everything. I take this and within an hour I'm in the bathroom. Once I take the pill, I drink a whole bottle of water and it helps a whole lot better. I usually go 2-3 times when I take the medicine. This medicine has saved my life."

10 / 10
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92 Report
  • Ms Tee
  • March 10, 2016

Linzess (linaclotide) "I have dealt with chronic constipation all my life. No matter how I change my diet, no matter how much I work out to keep things moving, I still get constipated. I can go weeks at a time with no BM and sometimes a whole month. I know this is definitely not normal. My doctor has done 3 colonoscopies and can't seem to find anything wrong. About 3 months ago, I went in with severe constipation and nothing I took helped. He gave me samples of Linzess. I was afraid to take them at first, but I was so miserable I said, 'What the heck, better out than in.' I took the Linzess and within 4 hours I was in the restroom. I still had to do just a little light pushing since the stool that was already in the rectal area was hard as a brick. I love Linzess."

10 / 10
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  • Cindy
  • Taken for 1 to 6 months
  • June 5, 2020

Linzess (linaclotide) "Have been taking linzess for about 6 months, and it worked great! The my pharmacy quit using Linzess, I was required to get a new prescription for a different drug. Because it worked so well, my doctor give my prescription to a different pharmacy. My insurance now says I don’t “qualify” , and the new prescription is $1600 for 90 days!!! The card from Linzess is not valid because I have insurance! So I guess I will use Ex-Lax because Linzess not available for me!"

1 / 10
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  • jeannie
  • Taken for less than 1 month
  • June 30, 2024

Linzess (linaclotide) "Reiterating what others have stated: When you start this drug, do it on your day off, or on a day where you do not have anything planned. This is so you will get to know how long it takes to work, and how your body will react to it. Take early in the morning. Wait at least 30 minutes before eating. I take it when I get up, usually 7-8. I run up to DD and get my daily iced coffee. Come home, put coffee in the freezer, take Linzess, and then wait 30 minutes. I then drink my iced coffee. Sometimes I will make some toast. Within 30-60 minutes of drinking coffee, I get the strong urge to use the bathroom. Usually once will do the trick. I strongly recommend you do not do your daily bathing or showering until after the Linzess takes effect. This drug does exactly what my doctor said it would do: cleans you out. No side effects. If I have an appointment or errand in the morning, I skip my dose and take it the next day."

10 / 10
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  • Arlin...
  • Taken for less than 1 month
  • August 5, 2013

Linzess (linaclotide) "My doctor said I have chronic constipation. Since laxatives stopped working, fiber supplements, water, fruit, and vegetables don't do anything for me. I had an entire bottle of Magnesium Citrate and it didn't do anything for me. I was so miserable and constipated that I didn't know what to do anymore. My stomach looked like a big balloon and I had gas. My doctor gave me 4 bottles of Linzess 145 mcg/capsule. I took it and it works. I am so happy I found out about Linzess. The first few days, the bowel motion was watery, but now it looks better. It's best to take it early in the morning with a tall glass of water. Within an hour, you will go. I am so happy to know about Linzess and I hope it keeps doing miracles for me. Recommended."

7 / 10
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  • GI nu...
  • February 23, 2015

Linzess (linaclotide) "I have severe chronic idiopathic constipation. And Linzess usually works within 2-3 hours after taking it. It doesn't work every time, but if it works 2 times a week, then I'm happy. Without it, I only had a bowel motion once a month at the most. And that's after using magnesium citrate."

10 / 10
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  • Keri...
  • June 25, 2013

Linzess (linaclotide) "I just wrote a note of appreciation to the physician who prescribed LINZESS for me. I have been taking it now for about three months, and it has truly improved my life significantly. After suffering from constant constipation for over thirty years, I am so thankful to have this life-changing medication. It works consistently and predictably every day without any noticeable side-effects. If my schedule does not permit its use, for example having an early flight, I simply do not take it that day. For me, this medicine has been miraculous."

10 / 10
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  • CPano
  • April 16, 2020

Linzess (linaclotide) "Have had problems with constipation following abdominal surgery. Dr. prescribed Linzess 72 and it worked perfectly right away, with no aftereffects whatsoever. I hope others with constipation problems consider this medication."

9 / 10
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48 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

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