Lupron and Sweating: What Users Say

• Pro...
• Taken for 2 to 5 years
• April 15, 2018

"My husband was only 41 years old and diagnosed with stage 4 prostate cancer. PSA was 59 and Gleason 9. It was in 5 lymph nodes. Surgery was not an option. He went through chemo and 45 rounds of radiation and has been on Lupron every 3 months for 5 years now (he was given 2 years to live). I thank God every day for having him here with me, but he isn’t the same man I’ve been with for the last 30 years. This drug is the only thing keeping the cancer from growing, but it’s destroying him and our marriage. The physical side effects are joint pain, sweats all the time, muscle loss and strength, and our sex life went from 5-6 times a week to 1-2 a month. Mentally, he’s a mess, and dealing with him is so hard. He went from having too much testosterone to none. He’s overly jealous, crying easily, sensitive, and just downright crazy sometimes, and he was none of these things before."

• Jus...
• Taken for 6 months to 1 year
• May 10, 2017

For Endometriosis "Many years of pain - After exploratory surgery and a part of one ovary taken, then laparoscopic 3 times to get rid of the endo, I thought this was going to be my saving grace! It has ruined my life, and I'm talking well over 20 years ago. If I remember correctly, it was a new drug they were trying at the time. Yes, it stopped my period and pain, but literally jumped from 110 to 140 in one month, had a complete breakdown, first time ever in my life breaking a glass table. Depression and anxiety and anger became my life. I reported all symptoms, even the little ones, such as sweating and not sleeping, hot flashes, etc. So not worth the lasting side effects, depression never went away! Don't use this drug, it took my happiness in life -"

• Fut...
• April 17, 2013

For Endometriosis "I was diagnosed with fibroids twice, an ovarian cyst 8 cm big, and endometriosis. I'm going to take my third dose in two weeks, and I was prescribed this medicine for six months. Pros: after the first injection, no periods! Five months without a period was right up my alley, being I had been bleeding so much for so long, I needed the break. Cons: if you eat salty food or heavy carbs, you feel like you are going to throw up. Hot and cold flashes, sweats, stiff joints, joint pain, headaches, sleeplessness/severe insomnia, dry skin and dry eyes. I could go on, but I'm doing this to rid myself of ongoing bleeding, pain, and infertility. It's worth it to stick it out if it really works, I don't know if it does yet, but I know I'm not bleeding."

• Mic...
• Taken for 1 to 6 months
• June 28, 2017

For Endometriosis "The hospital OBGYN decided to give me this while I was receiving treatments to prevent me from bleeding out (I have leukemia) and only told me I would get night sweats and a slight mood swing, and I would not get my period. I had my period for a month and a half straight, causing me to get transfusions almost daily. My bones feel like they're breaking, I went from 115 to 170, I'm constantly about to punch through things or cry uncontrollably, suicidal thoughts shot through the roof, blood pressure dropped, sweating so much, I can't walk much anymore without sharp pain and tiredness, etc. I begged them not to give me it on my second round of chemo, and they still did. Do yourself a favor and don't take this drug."

• Mau...
• Taken for 1 to 6 months
• August 19, 2015

For Endometriosis "I've received my first round in June 2015. Almost immediately, I started experiencing side effects. Headaches, weight gain, hot flashes, constant sweating, mood swings, made my depression worse, now swollen legs and ankles, also severe joint pain. This is becoming unbearable, and I'm rethinking doing the next cycle. It's helped with my endometriosis, which I'm happy about, but these side effects are a...."

• Bil...
• Taken for 6 months to 1 year
• November 30, 2024

For Prostate Cancer "I was diagnosed with high-risk prostate cancer. I opted for complete removal of the prostate and follow-up treatment of ADT and radiation treatment. My first injection was June 2023, and the second was January 2024. PSA test every three months since the first injection, and PSA was 0.00. I experienced many of the normal side effects from the Lupron injections, the worst has been the fatigue, joint pain, sweats, and hot flashes. It has been almost a year since my last injection. I still have some lingering side effects, with the worst and most often the sweats and hot flashes."

• Tom...
• June 16, 2016

For Prostate Cancer "Been on this drug for 15 months. No libido at all, day sweats, night sweats, and hot flashes, irritability, and erratic memory episodes. PSA from 30 to 0.01 after radiation and continues today."

• Bil...
• Taken for 1 to 6 months
• October 28, 2024

For Prostate Cancer "Hot flashes, heavy sweating. These happen all times of day and night. I am in the 3rd month of a 6-month injection. I don't yet know about the results."