Lupron Depot-Gyn User Reviews & Ratings

• Anonymous
• November 15, 2011

For Uterine Fibroids "This medicine has given me my life back. I no longer have to stay by a toilet due to extremely heavy periods that left me anemic. I no longer have pain during intercourse due to large fibroids and extremely painful periods. I was put on this medication to shrink fibroids for a safer hysterectomy or until menopause kicked in. I am 49, and I have had no side effects since starting this medication."

• my...
• November 3, 2010

For Uterine Fibroids "Lupron Depot 11.25 mg 3-month suspension has given me my life back. I have been on this for a month and saw my doctor today. His first words were, wow! It is shrinking my huge fibroids. I had constant bleeding with flooding every month. Finally, on Sept 8th, 2010, I hemorrhaged. I was admitted into the hospital unconscious. Thank God my husband had the presence of mind not to sign a consent form for an emergency hysterectomy. I spot rarely now and have lost 4 pant sizes because the fibroids have shrunk so much. I will take my second shot on Jan 4th, 2011, and hope it will put me in permanent menopause. I am 49 and will avoid surgery at all costs. My side effects have been mild at best. My experience has been fantastic so far."

• tir...
• January 8, 2010

For Endometriosis "I found Lupron to be effective in treating my symptoms of endometriosis, particularly painful menstruation. Lupron causes one to cease menstruating, which in turn eliminates the pain associated with month-to-month and/or every two to four week menstrual periods. That said, I developed a raised bump at the base of my skull on the back of my neck that itched and hurt. I became dizzy and lightheaded and dealt with short-term memory loss, along with joint pain in my feet, mouth-watering nausea, night sweats, nasal congestion, and acne. The doctor could not give me an answer about the raised bump, and that scared me, so I chose to discontinue treatment."

• mel...
• May 11, 2011

For Endometriosis "Been on this for 3 months. Yes, it does diminish the pain, but feel terrible by the side effects. Get mood swings, hot flashes, acne, and if that's not bad enough, weight gain. It's like you are a whole new person and not a very nice one. I have also been feeling very depressed. I only have one more month until my surgery, so I'm trying to stick it out. Best of luck, ladies."

• Dee...
• August 14, 2015

For Endometriosis "I began a 6-month course of Lupron with add-back therapy in January 2015. I was terrified from everything I've read online. I had none of the horrible side effects, some hot flushes here and there, but nothing unmanageable. I am a 41-year-old female with endometriosis. I was pain-free for the entire six months and felt good. Everyone is different, but with so many negative comments about this therapy flooding the Internet, I thought it might be helpful to add my 2 cents."

• klu...
• July 19, 2017

For Prostate Cancer "My experience on this drug mirrors that of Albert Owens. The side effects are truly awful, no energy, no sex, headaches, no sleep. I am either sweating or peeing all night. Deep depression, anxiety, nausea, memory loss, legs swelled, 2 stone weight gain around the middle, no quality of life left. I must agree with burned-out wife also because my wife feels just like her, and it is not nice. I have over another year on this stuff. I am happy for the men it has worked for, bless them, but for myself and others, it can be a nightmare. Take care and good luck to all."

• Flo...
• Taken for 1 to 6 months
• January 9, 2013

For Uterine Fibroids "I was having very heavy periods due to fibroids. My GYN gave me the shot, and it was amazing! No more periods! The trade-off I took was night sweats and early onset menopause, but after such heavy bleeding that I have a very low blood count, anemia, and vitamin D deficiency, it was well worth it! I'm only in the last few weeks of my first shot, but I can't wait for the next one!"

• 2-p...
• Taken for 5 to 10 years
• February 16, 2016

For Prostate Cancer "I have advanced prostate cancer and have found that when I stop or delay a 90-day injection, my PSA climbs. From June 2010 (PSA over 350) through Jan 2013 (PSA 9), my cancer was controlled. I suspended the shots for 18 months due to cost, and my PSA climbed to 270. In 5 months, my PSA is at 4.2."

• nik...
• April 9, 2010

For Uterine Fibroids "I didn't experience any major problems, except some mild stomach cramping initially and continued heavy bleeding for the first two injections. By my 3rd shot, just mild spotting and occasional cramping. I just finished my 4th round, still no hot flashes, etc. I'm actually looking forward to my upcoming surgery soon."

• Anonymous
• August 28, 2015

For Uterine Fibroids "I started taking Lupron in November 2014, and I am currently still taking the shots. I have had almost no side effects except for occasional hot flashes. I was put on Lupron because of heavy bleeding due to my large fibroids. I am extremely happy with the results. My fibroids have shrunk to the point that I can now have a laparoscopic hysterectomy rather than the old-fashioned full abdominal surgery. I haven't had a menstrual cycle in 9 months."

• enq...
• February 9, 2016

For Endometriosis "So my gyn started me on the Lupron a little over a week ago. I have had some horrible mood swings, severe pain worse than when I began, swelling in my hands and feet, and I started to bleed very heavily late last night. Has anyone else had these experiences? Did they get better over time? My biggest worry is I suffer from anxiety and depression prior to the injections. Things have been getting worse, is this normal, or should I be worried?"

• Jen...
• August 6, 2016

For Endometriosis "Absolutely horrible drug. Complete poison. I was given this five years ago for endometriosis. Did absolutely nothing for it, but I had all the horrible side effects. Five years later I'm still dealing with side effects of this drug. Bone loss, bone pain (to the point of just walking down the street sometimes it feels like my legs are going to break). My teeth are literally just shattering eating bread. My dentist looked at my records, then said we need to talk. This is what he said: 'Five years ago you didn't have anything wrong with your front teeth at all. You see this (pointing to the X-rays)? This is all bone loss. This doesn't just happen, it can't. This takes years and years and years to happen.' DON'T TAKE IT!!!"

• Opt...
• Taken for less than 1 month
• May 26, 2018

For Endometriosis "I am 54 years old. Obese and suffering from hypertension. Never had any gynecological problem. For the last 1.5 years, my periods became irregular and prolonged. And extremely painful. Initially, I thought it was due to menopausal changes. My gynecologist advised TVS (transvaginal ultrasound) and pelvis MRI, and it was diagnosed for endometriosis. I was advised a course of 3 injections of the dose. I hope it works for me."

• kml...
• September 20, 2015

For Endometriosis "I would never recommend this medication to anyone! The disclosure of the side effects isn't truthful. There are some serious, debilitating side effects that are not listed for this medication. I am the unfortunate patient that is experiencing the 'rare' side effects that weren't disclosed. I am suffering from short-term memory loss that gets worse every day. I never had anxiety problems until now. I shake/jittery and have tingling/numbness in my fingers, feet, and face. My nails are very brittle to the point I had to cut them all off. I am also losing my hair. I am severely constipated. My appetite is curbed, and I am losing weight instead of gaining it. And the headaches are terrible! Not worth having these side effects!"

• Iha...
• Taken for 1 to 6 months
• May 19, 2017

For Uterine Fibroids "I was on this medicine about a year ago, but I only took it twice over six months (it was an every three months shot). I did not see any difference in the size of my waist. I didn't have a professional test to show me a change in my size, I measured my waist each day. The measurement didn't change at all. Multiple doctors advised me that there would be no change, if any, due to the fact that I was very large. I recently had the Acessa procedure to help shrink the fibroids small enough to manage with a myomectomy surgery or hopefully without any other surgeries. At this point, it has been six weeks since the surgery, and I am too afraid to measure myself yet. Will update in a couple of months or so."

• Ter...
• Taken for 1 to 6 months
• November 5, 2018

For Endometriosis "My endometriosis pain did go away with the Lupron! However, I had major side effects! Swollen eyelids, nausea, exhaustion, joint pain, headaches, and my last symptom was hip bursitis, which I then stopped Lupron! Three months later, my endometriosis pain is back, and now I have hip bursitis in both hips! Climbing upstairs is agony for me! Between my knee pain and hip bursitis, my legs feel like they are going to give out completely! I’m praying this isn’t permanent for me!"

• Anonymous
• March 10, 2017

For Endometriosis "I have taken this injection on 12th Sept 2016. Now it has been 7 months, still, my period has not come. I don't know. Does this drug remain in the body for such a long time?"

• Sam...
• July 8, 2009

For Endometriosis "Been on it for a week and have none of the symptoms I experienced."