Leuprolide for Endometriosis User Reviews (Page 4)

• Anonymous
• January 22, 2009

Lupron Depot (leuprolide) "I have taken monthly injections for the past 6 months. I had a very difficult time for the first 6 weeks of treatment, but since then have not had many side effects. I had severe stomach cramping initially, along with migraines and mood swings. As those side effects subsided, the hot flashes began. With the hot flashes came nausea and unpredictable crying fits. My doctor put me on a low dose of Estradiol and Prozac. Within a few days, I was pretty much back to my old self, minus the horrible belly pains. I have to say overall the good outweighs the bad."

• Anony...
• Taken for less than 1 month
• December 11, 2018

Lupron Depot (leuprolide) "I received my first shot almost 2 weeks ago. I am on the 3 month dosage. Absolutely no side effects the first couple days, but pelvic/abdominal pain began day 3. My period came as normal on day 12 of getting the shot. I was really hoping to not have any at all. I will gladly deal with the more common side effects if my pain and period will go away! Only a few bouts of nausea and moments where I’ll feel so sad. I’m 39, no kids, and have been suffering with debilitating, life altering pain since 12! I’m praying this helps!"

• Trying...
• Taken for 1 to 2 years
• February 23, 2016

Lupron (leuprolide) "I took it 8 years ago for fibroids, cysts, and severe endometriosis. I was on Lupron for a year after trying other options. I had hot flashes and joint pain, plus a lot of the other symptoms mentions. Calcium and Vit D helped with joint pain. The symptoms remained consistent while I was on the Lupron, however even with the side effects, the year that I was on Lupron was the best I have ever felt. FINALLY no more debilitating pain. I got pregnant after the 6 month weening off period and had two kids. If endo is an inconvenience for you, maybe not the best drug. If endo is ruining your life, some side effects and symptoms are worth getting your life back. I am on it again and grateful that there is something out there that gives me relief"

• Anonymous
• November 8, 2009

Lupron Depot (leuprolide) "I was very pleased with my Lupron experience. I was on a six month course and found the first three to four months easy. I did experience hot flashes, mood swings, and slight insomnia. My fifth and sixth month were a little more difficult for me. The hot flashes became a little more apparent, the mood swings more frequent, and my face began to break out. To me, that was the worst. Along with the Lupron, I had a laproscopy 2 months before the medication and I started acupuncture treatments about a month before beginning Lupron which really helped with the side effects. My pain levels before medication were unbearable. I could hardly bring myself to get out of bed. I now notice that my pain level is low if I have any at all."

• KCMO
• Taken for 1 to 6 months
• May 28, 2016

Lupron Depot (leuprolide) "My first 3 weeks on Lupron were miserable. Painful, the heaviest period I've ever had, and just overall regretting my decision. It's now been about 2 months and I'm feeling amazing! Hot flashes and forgetfulness, yes. But the pain is almost completely gone. My pain had me bedridden some days and now my worst days just require a heating pad. I can't believe the turn around."

• bitch...
• June 11, 2016

Lupron Depot (leuprolide) "I was diagnosed with endometriosis during an appendectomy, but due to cluster headaches hormones were contraindicated. Eventually Lupron was advised. My mom, who NEVER had any menstrual cramps, told me horror stories and I reacted as usual and agreed to the Lupron injections, and I have lived to regret it. Like so many others, I had severe menopausal symptoms, mood swings that made my fiance think I was bipolar, and attempted suicide twice in a 3 month period, which is very unlike me. It caused weight gain, which I'd never had, and threw me into early menopause at the age of 46, 8 years after treatment. Now I'm suffering from acute hypertension and I'm at risk for a stroke, which can't be attributed to anything else. But hey, no cramps!"

• Singer
• September 4, 2019

Lupron Depot (leuprolide) "So I’ve been on Lupron Depot with an add back for 10 months. I have severe endometriosis. I would bleed severely every month for at least two weeks if not longer with the worst pain of my life. I wanted to die. I definitely wasn’t living. The smallest movements and I’d be soaked in blood. The pain was literally unbearable and I’d have to make a trip to the emergency room. Yes, I do have side effects from the Lupron Depot. Headaches, tired and drained, and for a few weeks out of my three month cycle, my body hurts so bad I can barely walk around. But these side effects have nothing on the pain and depression I was suffering before. I had no life at all. Everything revolved around my period. It’s the only thing that’s given me relief."

• Ang
• February 4, 2020

Lupron Depot (leuprolide) "My doctor told me about Lupron Depot, told me the side effects and I was weary because it's an antineoplastic. I started it along with the add back therapy of provera 5mg and had barely any side effects the first few weeks then I slowly started to gain hot flashes and some cramping in my right ovary where my cyst was. My period stopped before the second shot. I will say not to get it in the arm (deltoid) because my first shot was in my right arm and it hurt even a month after. I get my fourth shot on the 18th and I can tell you, the benefits will outweigh the negative side effects I'm having. So far I've had: thinning and loss of hair, my back and neck constantly hurt, hot flashes 2-6 times a day (mainly at night), vaginal dryness which causes a lot of pain during sex, mood changes (I cry a lot)"

• Ash
• January 4, 2020

Lupron Depot (leuprolide) "I have severe endometriosis and adenomyosis and am scheduled for a hysterectomy on Jan 29th. My doctor wanted me take get a couple of lupron injections so that I can have some pain relief as well as experience some of the symptoms I will be dealing with after my surgery. Well it's been 3 weeks since my first ( and LAST) injection. I have night sweats every night as well as a full aching headache all day long. The headache goes away with Tylenol or sleep but is back the very next day. So I'm hoping the headaches stop once this horrible drug is out of my system. Didn't have headaches until I got this injection!!"

• Lash
• Taken for 6 months to 1 year
• February 4, 2021

Lupron Depot (leuprolide) "I've been suffering from endometriosis and ovarian cysts for 22 years. After trying all the hormones, we discovered I also had fibroids and adenomyosis. My doctor performed a hysterectomy with RSO. Even with that, I kept having cyclical bleeding and endo pain. We agreed on starting lupron depot for 6 months with progesterone add-back. I was incredibly nervous because of all the reviews. The first 2-3 weeks were pretty rough. Migraines, emotions all over the place. By week 4, I felt amazing! As the first 3 month shot started to wear off, symptoms began returning and I couldn't wait for the next round. Dose #2 is coming to an end and I can confidently say I haven't ever felt better. This drug was a dream come true for me! We've decided to proceed with removing the last ovary and, hopefully, I can start truly living life."

• cj200...
• November 22, 2015

Lupron (leuprolide) "This drug should be taken off the market, It kills your immune system and the side effects never wear off. I had three injections in 2002 and am still suffering from what has happened to my body. The joint pain and hot flashes are unbearable. This medication has robbed me of enjoyment of life. It's only purpose is money for Big Phar and ease of surgery for the doctor. No Benefit to the patient at all. Do not take this, it will ruin your life."

• Anonymous
• Taken for 6 months to 1 year
• February 7, 2016

Lupron Depot (leuprolide) "I had a laparoscopy done march 2015 and they determined stage 4 endemetriosis. Before then I had maybe 1 week out of a month without pain for over a year, it was horrible. My first injection was in September 2015. I had a laparotomy in October 2015, the doctor did an amazing job, removed all the scar tissue and cyst's. My second injection was December 2015 and the hot flashes are brutal. I am now on a low dose of estrogen to help with the hot flashes. It has helped but not fully. I highly recommend the injection if you want to be pain free, the hot flashes are brutal but way better then the pain."

• l84appt
• Taken for 6 months to 1 year
• January 2, 2016

Lupron Depot (leuprolide) "I was on Lupron for a year (2006 -2007) and I have never felt the same. I am going on 50 but my body feels 100 years old. I was once described as a vivacious and enthusiastic individual. Today, I can barely keep up with friends and family (many of them are older than me). "

• Monta...
• September 18, 2016

Lupron Depot (leuprolide) "I was diagnosed with ovarian cysts and endometriosis at 18 years old (very early to find). I've suffered 4 years of this before I got diagnosed until eventually I was rushed to the hospital from the pain. My only option was lupron depot shot, I got the 11mg one. Worst decision of my life. I am thankful for having 100% coverage because it would've been a waste of money. I feel sad, depressed, anxious, its awful. I already have depression and anxiety. I feel like I'm going through withdrawals, I get heat flashes, the pills they give, what they call norlutate, didn't help the symptoms, I've noticed they made it worse, I had headaches every single day. I wouldn't recommend this shot. I'm still having period pain and its been 3 month"

• Kamcc
• Taken for 1 to 6 months
• October 11, 2016

Lupron Depot (leuprolide) "I started this about 6 -7 weeks ago after laparoscopy for small endo on my bowel and top of cervix was unsuccessful. The first month was a nightmare. Started with worsening pain symptoms and an extra-long last period. Mood swings were outrageous. Crying, all the time and a little feet/ankle swelling. Started adding back therapy and spironolactone a week ago and as I reach the end of month two, I'm pain free and I feel emotionally more stable. The side effects are manageable, at least right now. So if you can get past the initial period, it works."

• Robyn...
• November 13, 2016

Lupron Depot (leuprolide) "So I had BAD adverse affects to the Depo Provero shot.. SO bad that I lost my job. I had bad fevers for 6 months.. It felt like my body was on FIRE..No energy and it triggered hypothyroidism in me. I'm only 37. I have finally got to feeling better, the shot is out of my system as of a couple weeks back, losing weight now. No period yet, but my gyno said the next thing he could do is Depo Lupron.. needless to say I'm TERRIFIED! It's only the month shot, but I'm still scared to death. I already suffer with mental illness. I just wanted a hysterectomy to get this nightmare over with, so I could get back to life and never worry about this crap again. If you have any insight, let me know Thx."

• Mauya
• Taken for 1 to 6 months
• August 19, 2015

Lupron (leuprolide) "I've recieved my first round in June 2015. Almost immediately I started experiencing side effects. Headaches, weight gain, hot flashes,constant sweating,mood swings,made my depression worse, now swollen legs and ankles also severe joint pain. This is becoming unbearable and I'm rethinking doing the next cycle. It's help with my endometriosis, which I'm happy about but these side effects are a...."

• Anonymous
• April 7, 2012

Lupron Depot (leuprolide) "Had my first shot about a week ago. I have major pain in my joints (elbows and knees), hot flashes and night sweats. But honestly so far so good. I am no longer feeling the horrible endometriosis pain. Will update more once I'm further in. Plan as of now is to do 6 months of Lupron and see if my Fallopian tubes have less swelling and inflammation as my husband and I would love a baby of our own. Good luck to all. This is not easy. But I am hoping it will be worth it."

• skahlua
• Taken for 1 to 6 months
• November 8, 2016

Lupron Depot (leuprolide) "I got a month shot right when I was about to start period. Period ended up lasting about 12 days. I was told night sweats and menopausal symptoms would happen but I did NOT expect the suicidal urges (I've been diagnosed with depression but it was manageable before this shot), migraines - worst migraines I've ever experienced in my life, nausea, cankles. I've had to take roughly 5 days off of work just in the last 3 weeks and I may even lose my job. I am so irritable and cannot sleep for the life of me. I wake up at least 30 times a night. I'd rather have my excruciating menstrual cramps than go through this ever again. My body did NOT like this AT ALL!"

• Hysto...
• Taken for 1 to 6 months
• December 16, 2016

Lupron Depot (leuprolide) "At age 42 I had partial hysterectomy (uterus only) to remove large fibroids. (daughter was born when I was 32). Dr found stage IV endometriosis. He left my ovaries and said he never wanted to do surgery again - endo everywhere. He suggested Lupron to arrest the Endo. It took me a year to start Lupron. I had to contact a foundation to qualify to receive the medication for free. I did two 3 month shots. I remember some hot flashes, nausea & a few mood swings but it passed fairly quickly. Now, I am 46 and in full menopause. I have osteopenia with some degenerative disc issues. Chronic back pain hurts most when laying on stomach in bed. But I do not use pain meds or H.R.T. I hope the brain fog & other symptoms continue to improve."

• memem...
• Taken for 1 to 6 months
• September 13, 2016

Lupron (leuprolide) "Was prescribed Lupron after endo surgery since not all growths could be removed. I was very scared to be taking it after I read about it (I cried in doctor's office when getting the injection). But I ended up loving it. It stopped my periods and the pain, so my anemia was under control and I had so much energy! As for side effects, there was insomnia (but I was not tired from it, so it was OK) and hot flashes started after about two months - but that was nothing compared to the relief. I only got one 3-month shot, but the positive effects lasted for quite a bit. I hope to get another 3-6 months soon. I know there are risks to this, and everyone reacts differently, so I could not advise anyone to take it or not, but for me it was wonderful."

• Mimie
• February 28, 2021

Lupron Depot (leuprolide) "Straight after the injection I regret it because of the side effect but after 3-5 days it makes me feel better and it makes my life back. It has been 8 years that I have been in pain, 1 ectopic pregnancy and terrible pain every single period. To much medicine I had take and it is a risk to my kidney function and no medication help me at all. I just keep asking how come I only had this Lupron after 8 long years in suffering the terrible pain. It makes me feel better and be able to do the things that I never ever been doing for 8 years because 2-3 weeks in pain every period. Now I can do all the normal activities and it feel so good to be up in the morning after having a good sleep and pain free. I am looking forward for my second injection."

• pose
• Taken for 1 to 2 years
• February 6, 2016

Lupron (leuprolide) "I was diagnosed with stage 4 endometriosis after my 1st laparoscopy in june 2015. Following my 1st surgery i started Lupron injections in hopes to slow the endo growth. I had 3 rounds of Lupron causing terrible side effects which included but not limited to: fatigue, night sweats, mood swings, joint pain, severe abdominal pain, lack in sex drive, natural lubrication, anxiety.. Dec 2015 my 2nd laparoscopy and 6mths of Lupron left me with stage 3 Endometriosis. Doc wanted to continue with 6 MORE months of Lupron and another surgery. I declined such offer. I am very unhappy with how this drug effected my life.My body will never be the same after Lupron. Dont take this drug."

• Nasty...
• Taken for 1 to 2 years
• November 28, 2016

Lupron Depot (leuprolide) "I was diagnosed with stage 5 Endometriosis, back in the early 90's. My Dr. suggested to me the Lupron shots.. The reason we did not do the surgery at that time, I was young and wanted children, so to help with the awful pain, and miserable time of the month, we started Lupron Injections. Let me say, the side effects were awful! THE HOT FLASHES, I wanted to go out into the snow naked to cool off. The mood swings were out of control, however I was put through the menopause stage and no periods, that was heaven. I was on the injections for 6 months, then after I was off the wicked horrid pain and cycle started. The weight gain was insane. I had to go back on the injections, but since the weight gain, I quit after the 2nd injection."

• Renee
• May 28, 2018

Lupron Depot (leuprolide) "I personally have endometriosis and have had laparoscopic surgery for treatment. I have been told by multiple doctors that adding hormones to your body to lessen your “pain” (in quotes because no birth control has proven to do so for my endometriosis) so I have taken no birth control since my surgery 10 years ago and it has gotten easier to deal with not worse! They also offered two other options to stop the pain hysterectomy/ ablation.. either way would be fine since endometriosis will and has eaten up my reproductive organs. After the laparoscopic surgery it did take me 5 months to heal internally, so if you do this option please prepare yourself for a much much much heavier and DIFFERENT period for a least the first two months. But after sex seemed easier with less pain and going to the bathroom (taking a bowl movement) while on and off my period was much easier. Hope my experience helps anyone that has or has been recently diagnosed."