Leuprolide User Reviews & Ratings (Page 5)

• Hol...
• Taken for 1 to 6 months
• September 16, 2018

For Uterine Fibroids "This shot did not shrink my fibroids in my uterus before my operation. As a matter of fact, they grew. It’s going on four months since I’ve had the shot, I already had my operation. I do still have my ovaries. I’m still getting hot flashes. I have a headache every day of different levels. The nausea almost went away. Hot flashes are worse at night, so I’m losing a lot of sleep. For the last three weeks, my legs have been aching every day when I get up. I have no desire to have sex. This is definitely miserable. My doctor said the effects of the Lupron would be gone in three months, but they’re still here. I don’t recommend the shot for anybody for any reason."

• upt...
• December 4, 2017

For Uterine Fibroids "I was so skeptical about these shots, scared to death of the side effects after reading posts. I could kick myself! My shirts fall past my waist, I always looked pregnant. Slight headache, took generic aspirin, did the trick, hot flashes, weird but not that bad. Cycle, had one regular (heavy) period then skipped. Overall, I was so satisfied, I just called and ordered my second shot (I get them quarterly). Everyone reacts differently to different types of medication. What works for others may not work for you, but this did work for me. Good luck. Sorry for the grammar stuff, I was in a rush."

• Rid...
• Taken for 1 to 6 months
• April 4, 2017

For Prostate Cancer "I was diagnosed with prostate cancer in November of 2016. My PSA was 14.8, and my Gleason Score was 6. The good news is that the cancer did not spread outside the prostate and was in 9 out of 12 from the biopsy. I took Casodex for one month and had one Lupron injection, then started 44 treatments of radiation. Around treatment 20, my PSA went down to .09. After I complete radiation, I have one more Lupron injection to take, then that is it. No more cancer, I hope. The side effects are some hot flashes, weight gain, shrinking testicles, and frequent urination. After my next and last Lupron injection, I hope to be done with cancer."

• wor...
• July 26, 2015

For Precocious Puberty "My daughter was prescribed Depo Lupron when she was about 6 years old. I would never recommend it to anyone. She gained a lot of weight, became obese, has a lot of stretch marks, has high cholesterol, high sugar levels, sleep apnea, and uses a CPAP machine to sleep. She fights with me to binge eat. I am so sad, I feel guilty for using this drug. I wish I would have let her get her period, she would have only struggled for a little bit with that, than with a lifetime of health issues. Who cares if they stay shorter? Short is beautiful too, and even big is beautiful, but this med gives health problems that did exist. I feel like I scarred her for life :("

• Ton...
• Taken for 1 to 2 years
• July 24, 2020

For Prostate Cancer "Taking Lupron injections for 7 months, out scheduled 18 months for prostate cancer. Experiencing common side effects like hot flashes, weight gain, reduction in size of testicles. Completed 28 treatments of radiation this past May. Taking injections in the buttocks every 3 months. Injections are not bad. A little soreness for a couple of days. The side effects are manageable so far."

• Ema...
• August 11, 2013

For Uterine Fibroids "Received one shot for three full months. Nearing the end. Major side effects were the hot flashes and some weird feeling of uneasiness. I would not take it again. Hot flashes are not cool. Just had an ultrasound and will be seeing the doctor soon to see if the shot was a success in killing cysts. The drug may work, but wow, all these side effects."

• WHE...
• Taken for less than 1 month
• March 29, 2016

For Prostate Cancer "Nov. 2012, I had a double lung transplant. July 2014, I was told I had prostate cancer (this after several PSA's that never dropped below 4. My last was in the high thirties, and I had had 3 biopsies). Had a radical surgery in November, which included nerve scraping and removal of 11 lymph nodes. Post-surgery, I had no radiation but did have the long-term Lupron injections twice. I was cancer-free for a year, and now it is back. Started Lupron again, and the side effects are already out in full force (after 4 days). Because of my compromised immune system and the medications I must take for life, and kidney issues as a result of the lung transplant, I worry that the Lupron will not work. What would be an alternative treatment?"

• Anonymous
• January 25, 2012

For Uterine Fibroids "I was bleeding 24/7 and anemic due to a large fibroid. First, I tried Depo Provera shots, which didn't work. All bleeding stopped about a week and a half after my first Lupron shot. At this point, it's only been a month, so I don't know if I'll still need a hysterectomy."

• Kat...
• Taken for 1 to 6 months
• October 4, 2019

For Uterine Fibroids "I had the Lupron shot on 1st July 2019 for fibroids. It was fine for the first 2 weeks. Just slight breast soreness and general signs like I was gonna get my period. After the first 2 weeks, I started getting hot flashes, fatigue, and memory loss. Had a lot of problems recalling thoughts. I never bled since I had the shot, which was weird. I thought I'd get one last major period or something. I had surgery to remove my fibroid in early September. The fibroid never shrank. Guess the jab didn't work on me. I'm still getting the hot flashes, and the body aches, as well as fatigue, has gotten worse. I also gained weight! I found the drug increased my appetite. I still haven't gotten my period yet. Kind of happy about that but worried my hormones are all messed up. For reference, I'm 40 years old."

• klu...
• Taken for 6 months to 1 year
• July 26, 2017

For Prostate Cancer "I was diagnosed in September 2016 with prostate cancer, and I have been on Lupron ever since. In between, I had 37 radiotherapy sessions. I have to be on Lupron for 2 years, but I would love to end it now. It has done okay at lowering PSA, but my QOL has suffered greatly, along with that of my dear wife. My mental health has taken a big hit with extreme depression and anxiety, and bodily I have no strength and no ED. It works great for some men without any side effects, but for others like me, they can be overwhelming. Best wishes to all on this journey. Kluff."

• Mel...
• Taken for 1 to 6 months
• April 20, 2017

For Uterine Fibroids "Had a large pedunculated fibroid tumor on my uterus. The shot was administered, they found my fibroid got larger after 3 months. Had to have a partial hysterectomy to have it removed so I could sit, drive, and have sex without being uncomfortable or bleeding. I had every side effect, which was miserable. I had extreme hair loss (thinning), and I'm still trying to grow it back. This drug did not work for me. It has been over a year."

• Anonymous
• April 10, 2010

For Precocious Puberty "I was diagnosed with precocious puberty when I was 8 and started getting a Lupron shot once a month. It stopped all signs of puberty except the mood swings, which often worsened in the week before I got a shot. After 3 years, I was taken off the medicine and started puberty normally. I had continued to grow taller throughout that time and am now 5'1". My grandmother and cousin both had precocious puberty as well, and neither were treated. They both stopped growing around age nine and neither reached five feet."

• Eti...
• October 31, 2015

For Prostate Cancer "Stage 2B prostate cancer. Proton beam therapy coupled with six months on Lupron. Dreaded getting the second 3-month shot. Side effects: Almost total loss of libido and sexual function within 30 days-lasting for several months post-usage; debilitating hot flashes (2X/hour, 24/7); 15 pounds of weight gain; 50% increase in cholesterol under the same diet; dangerous liver impact (GGT > 130) without alcohol use; significant breast growth."

• cmf...
• Taken for 1 to 6 months
• August 19, 2015

For Uterine Fibroids "I had the 3-month 11.25 mg on 3/30/2015 to shrink my giant fibroid to the size that the laparoscopic myomectomy can be performed. I had no symptom of side effects for the first month and also had my period, but ever since the second month (May), the side effects have been really hitting me hard; including hot flashes and night sweats. I had my surgery at the end of June, and my doctor confirmed that I had reacted to the Lupron more than expected, as the fibroid not only shrank but part of it was degenerated. So, instead of a 2-hour operation, it ended up being a 6-hour one. Now, it's been 5 months, and the Lupron is still lasting (period still not back yet); don't know when it will be gone..."

• alp...
• Taken for 6 months to 1 year
• August 21, 2018

For Uterine Fibroids "I am 28 with a 21 cm x 13 cm uterine fibroid. I was told my surgery would be risky and would leave me with a scar from under my chest to my pelvic area. Since I am only 28 and would like to have children of my own, they decided to put me on Lupron for 6 months to shrink the fibroid by hopefully 50% and have a much smaller and less risky surgery. Went on the shot in June, with the first month being the hardest, with headaches, night sweats, hot flashes, and my first period being very heavy with lots of clots. But I am on my second shot, 2.5 months in, and I can say most of those symptoms went away. I only get hot flashes, which are definitely bearable."

• lup...
• Taken for 1 to 6 months
• November 7, 2018

For Uterine Fibroids "I had very heavy periods. My doctor offered a Lupron shot. I decided to go with 2 Lupron shots hoping it would shrink my fibroid. Instead, my fibroid grew bigger. It caused me horrible headaches with the strongest painkillers not helping. After each shot, my period would not stop for a month (at least it was not heavy). Hot flushes were horrible. Good night's sleep was gone. I would wake up multiple times a night, all drenched in sweat. After the effect of Lupron wore out and my period restarted, it was as heavy as before. The only benefit I got was not having a period for a few months (with some bleeding in between), but at a very high price (side effects and actual price). I think, as heavy as my period was, it was better to have my period for a few days a month than have frequent very bad headaches and constant hot flashes. I would not recommend it based on my experience. I would not have it done if I had to decide today."

• dOC...
• Taken for 1 to 6 months
• February 13, 2017

For Prostate Cancer "Hot sweats were the thing most mentioned and most noticeable. My apologies for lack of empathy to all those who I've known going through them. Muscle mass loss and decreased exercise tolerance. My total weight lifted in a usual workout fell to about 1/3. Dry scaling skin and increased dry hair. However, my creeping male pattern baldness was certainly less noticeable. Testicular size and libido took a hit."

• Cha...
• September 6, 2011

For Endometriosis "I LOVE LUPRON. I have stage 4 endometriosis, and Lupron has been AWESOME. I have only had one side effect: hot flashes, which I do not mind at all, they only come twice a day and last for up to 2 minutes. Hopefully, my husband and I can have intercourse without pain. I'm 23 years old."

• Mrs...
• Taken for 1 to 6 months
• November 3, 2013

For Endometriosis "I was given the three-month injection in July 2012, with no mention of the potential side effects. I have been off Lupron for over one year and still have debilitating bone, joint, and muscle pain. I have had significant hair loss, short-term memory problems, and depression. My physical disabilities mean I will probably have to give up work. It is disgraceful that this drug was given to me with no discussion around these life-changing side effects. I'm worse now than before I started!!"

• Ang...
• April 10, 2010

For Uterine Fibroids "I love that it completely stopped my outrageous heavy bleeding, which in turn made me anemic. So I am happy for that. However, the only side effect that I am experiencing is super dry skin on my arms, neck, and face... I feel it is aging me overnight. Some constipation, and not really hot flashes, but warm spells every now and then. Can't wait for surgery to get my hormones back to work."

• 23...
• Taken for 1 to 6 months
• November 18, 2013

For Endometriosis "I'm on day 48 of treatment and had my second shot on 11/04/2013. With the first shot, I bled 2 weeks prior and another 3 weeks after. After that, I haven't bled since. I'm being treated for lifelong (23 years) endometriosis. I have been disabled since 13 years old because of it. The only symptom I have had is severe non-stop hot flashes. I will have a hysterectomy in December."

• Sad...
• Taken for 1 to 2 years
• March 14, 2023

For Prostate Cancer "My husband cannot comment, as he died 5 years ago. He was diagnosed with stage 3 prostate cancer. He also had radiation treatments. He suffered from fatigue, depression, and insomnia. Radiation caused damage to the urethra. His prostate-specific antigen (PSA) test was low while on Lupron Depot, but he was miserable and committed suicide. It would have been nice to have an alternative treatment. He didn’t want to live that way."

• sur...
• Taken for 1 to 2 years
• March 27, 2021

For Prostate Cancer "Had a prostatectomy in Oct. 2019, and PSA rose in April 2020. Took bicalutamide pills and a Lupron injection in Aug. 2020, second injection in Jan. 2021. The next injection is May 2021. My side effects are mostly really bad hot flashes day and night, extra fat around my waist, and got the mood thing going. My wife said I should talk to the doc before the next dose. I also got an inguinal hernia after surgery. It is a hard drug to live with, but at 71 years old, I'll take it every day. I see the doc next month for a checkup after a blood test. I also had 39 radiation visits in Jan. 2021. I hope my PSA is still around 0.034 due to Lupron. I have to take a total of 5 injections, which have been every 4 months. Good luck to people who have to take this route."

• EJo...
• Taken for 2 to 5 years
• July 27, 2012

For Endometriosis "Six years ago, I experienced severe pain caused by an ovarian cyst and endometriosis. I eventually had my cyst removed, but after a few months, severe pain returned. I was dying of pain most of the time, until I could not tolerate it any longer. In August 2008, I was given Lupron Depot. The first month was a nightmare for me, I thought I was dying because of extreme bleeding. After that one month, my body slowly progressed. For three months, I had a 3.75 mg dose, and after that, I was on 11.25 mg. I am so relieved that it has allowed me to live a normal life. I am pain-free, and fortunately, the side effects were not too extreme. My last shot was in March, and I was supposed to have it last June, but due to the unavailability of my specialist, I am waiting for my next step. So far, I am doing fine."

• Anonymous
• November 15, 2011

For Uterine Fibroids "This medicine has given me my life back. I no longer have to stay by a toilet due to extremely heavy periods that left me anemic. I no longer have pain during intercourse due to large fibroids and extremely painful periods. I was put on this medication to shrink fibroids for a safer hysterectomy or until menopause kicked in. I am 49, and I have had no side effects since starting this medication."