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Femara and Weight Gain: What Users Say

Weight gain: mentioned by 7 users (10.4%)

Based on user experiences from 67 Femara reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

joint pain 44.8%
hot flashes 22.4%
hair loss 19.4%
pain 19.4%
muscle pain 11.9%
brain fog 10.4%
weight gain 10.4%
bone pain 9.0%
fatigue 7.5%
night sweats 7.5%

Reviews for Femara

Commonly mentioned side effects
  • dog...
  • Taken for 2 to 5 years
  • July 19, 2014

For Breast Cancer, Adjuvant "I was diagnosed in 2009, had lumpectomy, chemo, radiation. Managed to continue working through it all. Then took tamoxifen for 2 1/2 years... had horrible muscle cramping and hot flashes, switched to letrozole after determining I was postmenopausal. The major muscle cramps lessened considerably, as did the hot flashes. I took this for 2 1/2 years, just stopping 3 weeks ago. I have muscle, joint, bone achiness 24/7, no energy, tired always, feel like I'm in a fog, tinnitus, heartburn, slow metabolism with weight gain. How long will it take to reverse all of these side effects now that I no longer take it? I even quit taking ibuprofen because it doesn't do anything for the pains. I am now 2 months from being 50 years old."

5 / 10
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  • Mrs...
  • Taken for 1 to 6 months
  • September 21, 2013

For Breast Cancer "I was diagnosed with breast cancer (stage 2) - underwent 6 months of chemo and 6 weeks radiation. My hair regrowth was pretty quick but began thinning significantly after about a year of Tamoxifen usage (could see my scalp pretty clearly in the front and on top of my head). My doctor switched me to Femara about 2 months ago - side effects include lots of hot flashes (about 6-10 daily) and weight gain which I am combating by working out every day and cutting my calories. I am prayerful that I don't experience any more hair loss or the joint pain that I keep reading about. Everyone, hang in there!"

7 / 10
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148 Report
  • Anonymous
  • May 23, 2010

For Breast Cancer "I was on Tamoxifen for 2 years following breast cancer and doing fine. My oncologist wanted to try Femara because it could be a little better. I was on it for about 3 months when I awoke in the middle of the night with horrible joint pain. It had been coming on slowly, but I thought it was carpal tunnel, maybe arthritis. Then I realized that my doctor had said that joint pain was a possible side effect of Femara. I was also gaining approximately 2 pounds a month! I have been off of it for a month now, but am still having pain. It is worse in the mornings and evenings. Trying to grip with my hands is very difficult some mornings. My doctor said it could take a few months to get this out of my system."

1 / 10
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168 Report

Frequently asked questions

  • Can...
  • Taken for 1 to 6 months
  • August 18, 2015

For Breast Cancer "Diagnosed May 2014 with Stage 3 Breast cancer after chemo, removal of the tumor & lymph nodes, radiation. I started Femara, been on it almost 6 months and I have daily joint & muscle pain, fatigue, hot flashes, and most of all weight gain. I'm really trying to eat healthy and exercise, but working a full-time job, it's a tough routine to keep up with every day (55 and post-menopausal). But hey, I'm still here and hopeful the medication does a good job of keeping the cancer at bay. Doing my best with the symptoms."

9 / 10
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90 Report
  • Bus...
  • Taken for 5 to 10 years
  • February 26, 2020

For Breast Cancer "Caused me weight gain, serious hot flashes, did not have joint pain, headaches, or dizziness before starting this medication. I know these are listed possible side effects, however, these do cause some functionality issues."

7 / 10
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51 Report

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  • Not...
  • September 9, 2016

For Breast Cancer "Considering going off of it. Too many severe side effects such as painful hands and feet, tendinitis of wrists, weight gain."

1 / 10
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81 Report
  • lkw...
  • April 23, 2012

For Breast Cancer "I have been on Femara for 4 months. Hand pain and weight gain."

8 / 10
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107 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.