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Latanoprost ophthalmic and Fatigue: What Users Say

Brand names: Xalatan, Iyuzeh, Xelpros

Fatigue: mentioned by 6 users (8.7%)

Based on user experiences from 69 Latanoprost ophthalmic reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

anxiety 13.0%
burning 8.7%
cough 8.7%
fatigue 8.7%
sore throat 8.7%
blurred vision 7.2%
dry eyes 7.2%
joint pain 7.2%
nausea 7.2%
runny nose 7.2%

Reviews for Latanoprost ophthalmic

Commonly mentioned side effects
  • Gor...
  • Taken for 1 to 6 months
  • November 10, 2017

For Glaucoma, Open Angle "After using for one month, noticed cloudy vision, runny nose, sore throat, joint pain, and general fatigue. Finally realized all these side effects were from the drops and stopped using them. All above-mentioned side effects began to abate after 48 hours. This stuff is poison. People don’t usually think that eye drops affect anything other than eyes. They are wrong. Very wrong."

1 / 10
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158 Report
  • Jod...
  • Taken for 1 to 6 months
  • May 10, 2021

For Glaucoma, Open Angle "I am 52 years old, great shape and on no other meds. After about 4 months being on latanoprost I realized my joints hurt, like shoulders, hips & knees (I had ACL surgery years ago). I felt so stiff and sore and couldn't figure it out. Eye Dr nurse said she never heard of that before & pharmacist said a small % showed muscle and joint pain. That has gotten a little better... but I can't tell you how fatigued I am. I have NO ENERGY TO DO ANYTHING. I could sit all day long... that's not me!! I had a hard time believing two eye drops at night would do this, until I read all these reviews. Thank you for your time, everyone. I hope mine message helps someone. I'll go back to Dr and see if another Rx is an option, just to see if I get my energy back & joints feeling better. It's a fine line between that and treating my glaucoma....(!?) My pressure went from 21/22 to 18/17, so not as low as he wanted, he may switch me for that reason."

6 / 10
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77 Report
  • Ann...
  • Taken for 6 months to 1 year
  • September 12, 2018

For Glaucoma, Open Angle "No two generics are alike. I was on the Sandoz/CibaVision brand for 8 months. No side effects. Felt fine. My pharmacy changed the brand to Rising Pharma. Within 4 weeks, I realized this drug was making me physically ill. Fatigue, joint pain, nausea, headaches, pressure behind my eyes, sinus problems, anxiety, blurred vision, dry eye. Everything on the list of side effects. I stopped taking the drops & within days the side effects greatly subsided. A medication should not do this to a person just because it's from a different pharmaceutical company. FDA should track this information. Anyway, my doctor took me off these eye drops. Considering Selective Laser Trabeculoplasty (SLT)."

2 / 10
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91 Report

Frequently asked questions

  • Woo...
  • Taken for less than 1 month
  • July 11, 2022

For Glaucoma, Open Angle "I took Latanoprost for two weeks. I experienced insomnia beginning the first night. It took a little while to make the connection because insomnia was not listed as a possible side effect in the information provided with the prescription or with initial online research. I was awake all night or waking up every hour, which led to extreme fatigue and inability to focus or concentrate during the day. After doing further research, I eventually found one site that listed insomnia as a potential side effect. I stopped Latanoprost and switched to Brimonidine two days later. The insomnia stopped immediately! I'm not sure if I had any other side effects because I was so disoriented by the insomnia. So far (two weeks), the only side effect with Brimonidine is minor drowsiness, which is manageable since I know what to expect. I have looked at some of the posts here and was very surprised that insomnia has not been mentioned. I don't take any other meds, so it was not due to an interaction."

1 / 10
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20 Report
  • Sus...
  • Taken for less than 1 month
  • January 25, 2023

For Glaucoma, Open Angle "Used Sandoz brand for years with minor issues. Pharmacy changed to Greenstone, and I am nauseous 24/7 with extreme fatigue and major reflux issues. Only taking this brand for three weeks, but getting more and more scared."

3 / 10
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7 Report
  • Vit...
  • Taken for less than 1 month
  • June 21, 2022

For Intraocular Hypertension "I have been on latanoprost for just over a week. I'm experiencing anxiety, lack of focus, mild palpitations, and some kind of dizziness. I have trouble focusing and have been feeling fatigued throughout all this time. My doctor says to use it for another week and then stop a week before I visit him again. This way, he reckons he'll be able to tell whether or not to take me off it completely or change the drop."

5 / 10
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4 Report

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