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Irbesartan and Insomnia: What Users Say

Brand names: Avapro

Insomnia: mentioned by 9 users (8.5%)

Based on user experiences from 106 Irbesartan reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

tiredness 26.4%
dizziness 13.2%
anxiety 10.4%
fatigue 9.4%
cough 8.5%
headaches 8.5%
insomnia 8.5%
pain 8.5%
lightheadedness 7.5%
nausea 6.6%

Reviews for Irbesartan

Commonly mentioned side effects
  • Dre...
  • Taken for less than 1 month
  • September 13, 2018

For High Blood Pressure "I was given 150 mg of this medication for moderate high blood pressure. I’ve never had a negative reaction to any medication until this stuff. While I realize everyone is different, this stuff shouldn’t be allowed on the market. I only took it for 3 days but I can’t even begin to tell you how terrible it made me feel. Anxious, extremely tired - yet inability to sleep at all (up 100% of the night), brain fog, feeling like a zombie, and weird buzzing feeling. This is a terrible medication and I don’t suggest anyone take it."

1 / 10
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120 Report
  • Gag...
  • October 24, 2017

For High Blood Pressure "I started getting leg cramps at night. I got lots of anxiety and couldn't go to sleep. I would get up to go to the bathroom 3 or 4 times during the night to urinate. Also, I had stiffness in my neck and hands. I have blurry vision, swollen eyes, and headaches. I have been taking irbesartan for 3 years. I'm going to stop for a while to see if the side effects go away."

5 / 10
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81 Report
  • Des...
  • Taken for 5 to 10 years
  • January 24, 2018

For High Blood Pressure "I am so glad I found this site. I have been on irbesartan for several years and have had a dry cough, sweating, tiredness, increased urination, trouble sleeping, sometimes shortness of breath, muscle cramps, and general lack of interest in things. After reading these reviews, I feel sure that these symptoms must be down to the irbesartan. My doctor put me on to this drug because strokes are in my family. I'm going to stop taking the tablets whilst monitoring my blood pressure."

4 / 10
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  • Dav...
  • Taken for 1 to 6 months
  • September 25, 2018

For High Blood Pressure "Been taking this med since the Valsartan recall. Have had bouts with insomnia and anxiety. Does okay with improving BP, but the side effects are not worth it. Dr. prescribed a mild sedative, but I just want to be off of this med...and get normal sleep again."

4 / 10
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48 Report
  • Maz...
  • Taken for less than 1 month
  • November 19, 2018

Avapro (irbesartan) for High Blood Pressure "I was prescribed Avapro by a neurologist this month for consistent mild high blood pressure and numbness in hands and left foot. Also, an MRI, which I had today, to exclude cervical stenosis. I am already MTHFR genetic mutation that depletes vitamin B12, folate, vitamin B6. I have had increasing numbness in my left hand on waking and general weakness and strength. Since taking Avapro, symptoms have gotten worse. I am tired with depleted energy, nauseated, aching hips, disturbed sleep even with a sleep apnea machine. Just saw my doctor who suggested taking Avapro in the evening as that’s when my BP is the highest."

2 / 10
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43 Report

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  • Syl...
  • June 18, 2016

For High Blood Pressure "I've never felt ill, but the doctor said I had high blood pressure and put me on 125 mg. But a few weeks ago, they upped my dosage to 300 mg. Everything was fine, but I've developed a dry cough, now get cramps, cannot sleep, and today have come out in a raised, itchy, very red rash on my arms, legs, neck, and chest. I'm going to the doctor, as this doesn't seem right, and I can't cope with all these side effects."

6 / 10
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  • Mab...
  • Taken for less than 1 month
  • April 11, 2021

For High Blood Pressure "I was on a low dose of Avapro for 8 months. I developed muscle pain, joint stiffness, and a swollen lower left leg. I started to wean off some of my medications to see what the culprit was, but my BP went high. After an admission to the hospital, they commenced lisinopril and I felt great until the cough with severe choking episodes came on. So, not convinced that Avapro had caused the previous problem, the doctor recommenced it but at double the dose. I now have urinary frequency, swelling of the lower legs, episodes of tachycardia and irregular rhythm, low back pain, tendinitis in the right hip, sore hands, redness of the face, insomnia, numb fingers, sore muscles, and positional dizziness. BP is great, but this is only after 3 weeks of treatment. Time to try another drug group."

3 / 10
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  • 2ja...
  • March 2, 2009

Avapro (irbesartan) for High Blood Pressure "ALERT!!!! I could not be awakened from a deep sleep the second time I took this drug. I realized later, I almost went into a coma! I slept for 13.5 hours, and a friend had to wake me up, pour coffee down me and make me start walking. I did not even hear my dog trying to get me up. It took over 48 hours to recover. I threw all of the samples out!"

1 / 10
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71 Report
  • ste...
  • Taken for 1 to 6 months
  • January 6, 2023

For High Blood Pressure "This worked in 3 weeks to bring down BP from 160s/90s. Now it's 130/80. But the side effects are scary: loss of libido, weak erections, loss of appetite, tingling in feet, muscle twitches, neck pain, irritability, impatience, breathing problems within the first 3 hours of taking the 150 mg daily morning dose, loose bowels, anxiety, disturbed sleep, heart palpitations, and general feeling of dis-ease. Apart from these, I am happy with the BP-lowering effect, but I don't want to continue with these side effects, so I'll be asking my GP for an alternative in the coming days."

7 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.