Skip to main content

Avonex and Muscle Pain: What Users Say

Muscle pain: mentioned by 3 users (6.5%)

Based on user experiences from 46 Avonex reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

flu-like symptoms 32.6%
headaches 15.2%
chills 13.0%
pain 10.9%
tiredness 8.7%
insomnia 6.5%
muscle pain 6.5%

Reviews for Avonex

Showing 3 reviews tagged with "muscle pain". Clear filters to view all 46 reviews.
Commonly mentioned side effects
  • Nhl...
  • September 13, 2017

For Multiple Sclerosis "I just started this medication. With each injection, the side effects have gotten worse. I did my 3rd dose last night, and I'm miserable. The body/muscle aches, headaches, etc. are about unbearable. Each time, I took two 500 mg Tylenol before my injection as recommended by my training nurse. I was told about the flu-like symptoms, read the booklet my neuro gave me, but I thought the symptoms would subside at least halfway through the next day. I am so pained. I keep taking Tylenol and even my muscle relaxer, hoping for relief. But nothing seems to help. I called into Biogen after my 2nd dose. No help. Copaxone gave me bad brain fog and injection site reactions. Tecfidera kept me in the bathroom in unbelievable pain. Not sure what to do now."

2 / 10
Was this helpful?YesNo
19 Report
  • Msr...
  • Taken for 2 to 5 years
  • August 5, 2017

For Multiple Sclerosis "I am almost 68 years old; diagnosed with LOMS in '15. Immediately went on Avonex (weekly self-injectable pen). Symptoms have not progressed, and I am stable over the past 2.5 years. I do well with the shots; have learned to travel with medication and have taken care of my needs worldwide! I initially had flu-like symptoms post-injection, but they dissipated over time. Here at 30 months later, I had a really bad episode of wracking chills and muscle aches just last PM. I feel worn out and sore this AM. Why, after all this time, did I have this reaction? I have never missed a dose, so it's not like I am reintroducing medication to my system. Is anyone else having this problem?"

Was this helpful?YesNo
9 Report
  • chi...
  • March 25, 2010

For Multiple Sclerosis "I have had MS for over 25 years now and have been on Avonex for about 2 months. I find the shots to be tolerable (given to me by someone else), and the side effects are not too horrible. About 6 hours after injection, I have chills, muscle and joint aches, and a slight headache. These effects last for approx. 4 hours. The following day, I feel tired but okay. Not sure if it is helping. I hope so... time will tell. After all is said and done, the shots and the side effects are not so bad."

5 / 10
Was this helpful?YesNo
13 Report

Frequently asked questions

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.