Imipramine and Heart Palpitations: What Users Say

• Cha...
• March 27, 2017

For Panic Disorder "This medication saved my life! I've only been taking it for almost 2 weeks, but I was thrilled at the fast response I had to it! I've literally tried almost every other antidepressant without much success for over 20 years - for my debilitating panic disorder/GAD/depression. Thank you to the Dr. who started me on this recently while I was hospitalized for a suicide attempt. I can now leave my home without any fear or anxiety, my panic attacks/panic are literally gone! I feel like a new person! The only side effects I've had so far are dry mouth, dry eyes, and a bit of tachycardia. It also helps me sleep for once, I take it at bedtime. I was titrated up to the 100mg dose once at bedtime. I cannot emphasize enough how happy I am to have this!"

• Sul...
• Taken for 1 to 2 years
• November 13, 2017

For Depression "I was on imipramine for a little over a year, after trying every other antidepressant known to man. At first, I noticed a major change. It was the best I had felt in years. I was back to doing things that I used to do and felt great. It also helped me to sleep at night. The effects of the med started to decrease, so we increased the dose until I was eventually on 100 mg a day. That's when the side effects started. I went in for a routine doctor visit, and my resting heart rate was 130. Of course, panic set in, and I had a bunch of tests ran on my heart, everything was normal. The only thing different was the increase in imipramine. It caused me tachycardia. So now, I am in the process of weaning off of it. Onto something else."

• Amy...
• Taken for 1 to 6 months
• June 2, 2020

Tofranil (imipramine) for Depression "Tofranil made me painfully constipated, very nervous, irritable. Between doses, I'd get extremely weepy and emotionally distraught. It was the only time in my life that I felt life was too hard. When I started experiencing heart palpitations, I stopped taking it. I have CPTSD and borderline."