Hydrochlorothiazide / lisinopril and Joint Pain: What Users Say

• CKa...
• December 16, 2020

For High Blood Pressure "I started this drug combo hydrochlorothiazide with lisinopril 3 years ago, and I didn’t realize what it was doing to me. I began to suffer serious joint pain, numbness/tingling in hands and feet, and overall muscle pain, which continued to increase over the last 3 years. The doctor diagnosed me with an autoimmune disorder as I went from a perfectly healthy 55-year-old male to crippled in 3 years. I couldn’t do anything. Through experimentation and never wanting to accept that I just all of a sudden had succumbed to an autoimmune disease, I began eliminating supplements, drugs, and foods from my diet. 2 weeks ago, I finally weaned off of lisinopril, and I am 100% sure that this was the cause of ALL of my ailments. I am on the road to full recovery as every day my symptoms are improving significantly and are mostly gone. My life was ruined for 3 years on this drug. Stay away from it or at least be aware of the symptoms early on so you can stop it."

• Emm...
• April 4, 2016

For High Blood Pressure "I was on atenolol for 15 yrs with leg swelling, facial swelling, headaches, joint aches, insomnia, no restful sleep, erratic bp in maybe 1 hr. Switched to lis/hctz 10/12.5 3 yrs ago. The only pill I take. BP steady 125/80. Throat sore, swelling closed, mouth breather, headache 12 hr after taking, tinnitus, dizzy when rising, then began vertigo, real vertigo. Dr said food allergy, stopped lin/hctz for 3 days = BP high, no tinnitus, no dizzy, no headache. 3 days ago had a bleeding floater in left eye. This morning, the ophthalmologist said lin/hctz can affect floater and macular degeneration. Deciding what to do.... lose 50 pounds and get off drug! Or put up with side effects and go blind?"

• Bet...
• Taken for 2 to 5 years
• January 8, 2022

For High Blood Pressure "This medication almost crippled me! Over the course of a year, my joints became so painful that I could barely climb or descend stairs without crying out in pain. This just started out of nowhere; I was perfectly able-bodied then - crippled. I started researching arthritis, MS, etc. On a side note, I ran out of blood pressure meds and went without for almost 2 weeks. Miraculously, my legs and knees got noticeably better each day! I figured it was a coincidence and started my BP meds again. All the joint pain came back. I did not truly make a connection until I stopped my meds again for 3 days, and I was able to deal with the stairs almost pain-free! This time I am convinced there is a connection with the Lisinopril HCTZ and looked online: there it is - muscle and joint pain! It is worth noting that I was on this med for 2 years before this happened to me. It does control my BP. So, it can start at any time. Be aware."

• Ang...
• Taken for less than 1 month
• June 13, 2022

For High Blood Pressure "I started on this medicine 5/4/22. Ended up with a 2-day stay in the hospital because of it 6/5/22. Within 3 days of starting it, I got a terrible ringing in my ears. To the point I couldn't hear the TV. Next, every time I stood up, leaned over, or turned my head too quickly, I got terribly dizzy. Then my feet and ankles got so sore it was really hard to walk. I stopped taking it on a Sat and went to the Dr. Mon morning. Dr. told me I'd feel a lot worse if I had a stroke. But he cut down to half a pill. I took the half pill for about 5 more days, and by then I felt unsafe even walking inside my own home. Between the dizziness and terribly sore feet, I was very unsteady. At the ER, they tested my potassium level, and it was way too low. Under 2.5. So I had an IV for a day and a half. I think this is supposed to be easy on your P levels, but for some reason, it did a number on mine! I still can't walk right, I just hope it clears up. And my BP has been 90/60 w/o meds, so I have no idea, but I will never take it again!"