Hyaluronidase for Dissolution of Dermal Filler User Reviews (Page 2)

• Life...
• Taken for 1 to 6 months
• January 30, 2022

"This substance is very intelligent and extremely evil. I'm 5 months in and no signs of withdrawal. It attacks in sessions - you never know where next attack will be. My whole body affected - now my joints and tendons. Eyes totally destroyed. I went from 100% working to being disabled over night. Ugly big brown spots on skin emerging from nowhere. Facial skin always edematous and jelly-like. The palm of hands has dried out and skin on the top of hands wrinkly and loose. Skin collapses on top of blood vessels making them bulge on hands and feet. The burning pain and agony is unbearable due to the targeted slow process. Substance is hiding and is manufactured to look like body's own. Doctors will never find it and will give you substitute explanations. Not sure I will survive this. There's no antidote existing."

• Jean
• July 31, 2021

"Hyaluronidase must be used with caution. All too often doctors or dermatologist inject far too much when trying to dissolve filler! They are just too heavy handed! Also it must be dissolved in enough saline! Sometimes it's too concentrated or not dissolved properly before being injected! Please ensure you see a reputable and knowledgeable practitioner and ask them to proceed slowly - bit by bit at a time! And wait a few days in between, to see the effect. I hope this helps a bit. I used it to dissolve filler and it worked fine. But use caution."

• Ptt
• Taken for less than 1 month
• June 6, 2022

"I was injected with 2 full undiluted syringes to dissolve undereye filler. The dermatologist explained to me she does this all the time with no issues, needless to say I was in the ER that week.. The months following were horrific.. night sweats, hallucinations, gums receding and teeth numbness, nerve damage, constant blood in nose, eyesight, burning which spread from my undereyes all the way through my cheeks then ears then neck then hands and legs and what looks like feet at month 4-6. Fat became jellylike. . At month 4 I had a reaction from something I ate, the whole inside of my nose and around burned and scabbed up. I'm 6 months and the systemic issues are out of this world. Constant infections, hair falling out, eyelash loss, cartilage changes in nose and ears, skin on whole body is becoming loose. Joint pain, head pressure etc etc etc."

• ACM
• Taken for less than 1 month
• March 27, 2022

"I recently had filler excess dissolved from under my eyes. I took initial swelling and discoloration as due to the lidocaine mixed in but am wondering if it was another side effect from hyaluronidase. I am very sad to say I truly regret having this injected. It's been about 45 days and my under eyes are not only sunk in at the outer corners but I also have huge bags as if they were herniated due to the loss of connective tissue. I had my 2-week follow up appointment and we were happy with the dissolving results, except that it kept dissolving. Another 2 weeks and I returned for a re-fill and mentioned the bags. I think what hurt me the most was how the injector completely dismissed me and implied that I probably did something to my eyes as they looked so different than the last visit. Regardless, as so many other women here, I am now on a quest to find a solution. It's very unfortunate that injectors and doctors use this drug all the time without understanding how terrible it can be."

• Dra...
• Taken for 1 to 6 months
• October 20, 2021

"This was used to dissolve filler. Unfortunately, an inept doctor overcorrected my tear through and after 5 months and asking colleagues who supposedly knew, they didn't tell me anything about the side effects. I wanted to put less units but the doctor who did it told me that it was little , a disaster. I am a doctor and there aren’t articles which mention the loss of tissue or skin, the doctors do not say it, it can only be used in an emergency."

• Bodour
• Taken for less than 1 month
• October 1, 2021

"I treated my under eyes filler with hyaluronidase. It resulted with hyperpigmentation and loss of tissues under eyes. I experienced bad hollow. Dermatologists asked me to fill the hollow with filler again after 10 days and I did. Very worried about my own skin and this color that I have now. I don't know what to do now"

• Ban...
• Taken for less than 1 month
• June 9, 2023

"I had too much filler in my cheeks under my eyes and had hyaluronidase injected to remove it. Within days I felt a burning pain sensation in the sinus and nose and within a month my inner eye caved in, I had dark areas of skin, and nose depletion. After 5 months I am still in pain."

• Mama
• August 21, 2022

"This product has devastated many users. It most certainly can and does destroy your own tissue. There needs to be more disclosure about it. It can melt connective tissue and cause significant sagging on the tissues, especially in the face. It's criminal that people are injecting this stuff into others without fully disclosing the risks"

• Damaged
• Taken for 1 to 6 months
• August 14, 2022

"I used hyaluranidase to dissolve filler under my eye before my facelift and was left with dark pigmentation that I did not have beforehand. I read all these comments and I’m wondering if anyone has contacted a lawyer? The pharmaceutical company doesn’t have a warning label."

• RBK
• Taken for 1 to 6 months
• August 1, 2022

"If your doctor tells you its safe, run! I thought I could take risk, that it’s used all the time. I saw these reviews but my doctor promised he’s never seen any side effects. These past two months have been hell. I’ve had face burning, head burning, eye burning, dry eye, fatigue, terrible eye bags, volume loss, saggy skin. I don’t recognize myself anymore. I am getting tested for nerve damage this week. If things don’t get better I don’t know how I can live like this."

• Sarah
• Taken for less than 1 month
• April 2, 2022

"Shocked at so many scary reviews and sad for people’s negative experiences . I personally have had hyaluronidase for filler dissolving on around 6 different occasions over 4 years for lip, chin, jaw dissolving with no issues at all. Had tiny swelling, minimal bruising which went with a few days to a week maximum. Also went to different injectors for dissolving with same results. Noticed no difference in my skins elasticity, texture etc apart from with lips but they then went back to normal after a few days. I was patch tested each time and only proceeded with following no reaction after around 20 minutes."

• Ooo
• Taken for less than 1 month
• April 21, 2024

"I was injected with 200 units of hyaluronidase in late January, and it has ruined my life. There is pain throughout my entire face. My chin, my jaws, my cheeks, even my forehead, are constantly in pain. The pain is debilitating, and I'm terrified I will never heal."

• AshleyA
• March 13, 2023

"I got hyaluronidase two separate times in my upper lip to dissolve the migrated filler. It destroyed my lip tissue. I have dents in the places she injected, I'm not sure if she did it unevenly or put too much but the corners of my mouth dropped and my cheeks sagged. I have parenthesis lines around my mouth I didn't have before because of the sagging. It aged me 10 years. I have barcode lines on my upper lip as well. I'm disfigured. I look much, much worse than I did with migrated filler. I regret so much I went into a depression. I look so bad, it looks so strange. I used to be a beautiful girl, I was a model. And now my looks are gone at 35. I was not told this could happen, I was told I look the same as before the filler. My injector admitted it dissolved my natural tissue and I lost structural support. It continues to get worse over time. This filler was 10 years old. It did not dissolve on its own like I was told it would. My quality of life is significantly affected."

• Anonymous
• Taken for less than 1 month
• October 21, 2021

"I had this to remove dermal filler under the eyes and cheeks. The dermatologist used too much hyaluronic acid based filler in my tear troughs, cheeks and mouth. I had two sessions of hyaluronidase treatments in these areas to remove it. After the first session, I noticed crepey skin under the eyes and was horrified. I did not have this prior to treatment. I mentioned this to my doctor and he said it was temporary. Time has gone by and it’s not temporary. I’m so distressed. I’ve aged 10 years in a month. Some of the overfill was removed, but not all. I would never agree to hyaluronidase treatment again. The doctor should cautiously inject dermal fillers to avoid overfill. Hyaluronidase treatment will permanently wrinkle your skin and create hollows under the eyes."

• Crystal
• Taken for 6 months to 1 year
• June 23, 2022

"Had the filler under my eyes dissolved with a small amount of hyaluronidase. My skin has never been the same! I have hollowing at my temples/sagging in my jawline/dry flaky skin and orange peel texture that I never had before! Not to mention gaping hole underneath my eyes/my tear trough. Please do not allow this product to be used on you!!"

• MAha
• Taken for less than 1 month
• April 27, 2023

"When I was 27 years old, I made the decision to dissolve the filler in my face, as I had always looked younger than my age. However, the enzyme used in the process ended up melting my face, and the doctor injected too much of it. Despite the passage of several years, my face has not fully recovered. I still have dents and sagging caused by the enzyme, and my entire scalp has shrunk. My family and relatives frequently comment on how saggy my face looks. My coworkers have said that I look much older, and members of the opposite gender are no longer interested in me. I experience a lot of rejection now before I was able to attract anyone I wanted. This experience has had both emotional and physical consequences that have persisted for years. Now that I am in my 30s, aging has hit me much harder than my peers, as my face was already compromised and sagging. I strongly advise others to stay away from this procedure."

• Hylenex
• March 23, 2022

"This was used for Female, 28 yo. Nasolabilas' fold filler dissolving. Loss of volume overall on face, skin laxity, apparition of hyperpigmentation marks, enlarged pores, entire face skin thinning. All effects appeared within a week from the injection."

• Cryst...
• Taken for less than 1 month
• March 23, 2023

"I have been systematically damaged by hylenex after getting my lip filler dissolved. What was supposed to be “safe” and effective” has changed my life for the worse. I’m 30 years old and my facial skin is loose, very thin, textured, saggy, my eye lids are covered in veins and have lost their almond shape, my entire face had sunken and dropped. The skin on my body is thin and see through, you can now see veins everywhere where you couldn’t before, it’s especially noticeable on my hands, chest and feet. I have a greyish hue to my skin. I was never told this could happen from dissolver and have been dismissed by doctors. This has been an incredibly traumatic experience and it doesn’t appear I will get any sort of help. Please think twice before dissolving. I’d only use it in an emergency setting. My situation was not an emergency, I just didn’t like how the filler was placed. I’d much rather have wonky filler than this. I don’t know how much longer I can bear this."

• Bambi
• Taken for 1 to 6 months
• September 18, 2022

"I had a full vial of hyalase injected to dissolve 1.5 mil of filler. Less than 2 months later it caused my temples to sink in and hollow. Has also sunken in my cheeks and resulted in stretchy skin. Other more mild side effects include blurred vision and thin skin that sags, hollowing of eyes and pitting edema. Do NOT ever risk using this product, the effects are highly unpredictable. I feel as though it has resulted in rapid ageing within months. I’ve been researching and many people have experienced ongoing deformation of their faces for up to 3 years. I am so afraid it will cause my face to collapse and I wouldn’t want anyone else to experience this. The product is NOT TGA or FDA approved for aesthetic use. Instead it is used off shelf when it comes to dissolving filler. Hyaluronidase is also known to play a role in cancer. It’s simply a dangerous product and it’s current use is entirely irresponsible and should be made illegal for use in cosmetics."

• Sad...
• Taken for less than 1 month
• August 22, 2022

"I really got lied to right to my face and asked repeatedly if it could hurt my eyes. I specifically asked because they shoot it with a cannula right towards your eyes to remove eye filler. Then later talked down to by another nurse injector. Vitrase ruined my eyes and stole my vision. It's left me with constant eye itching and I cannot wear makeup. Dry eye and corneal inflammation. Skin inflammation that doesn't stop. I am so sad. They didn't tell me anything like this could even happen. That it was safe for the eyes well it isn't, I have read lots of articles about the damage it can do to the cornea. Not to mention what its done to my face and self confidence. And now I cannot even see, even with glasses. It is not even FDA approved for this use. Its also cost me more money than I can say because of all the medications and Drs to try and fix my eyes."

• Danelle
• Taken for less than 1 month
• January 7, 2023

"I had hyluronidase (hylenex) in my nasal fold area. Day 2 I had itchy eyes almost dermatitis looking & that evening, I couldn’t sleep. I had pain in my head like someone was squeezing it & tingling in my nose. The next day I had weird skin indentions like I had slept on it but I hadn’t slept there. These lines come and go. I got a double steroid shot day 5. I am still having pressure in my head, my eyes have sunk in some due to tissues being dissolved. It took all my filler out everywhere and then my own. This stuff is toxic and evil. Has anyone tried a SOT treatment. I’ve read there's a place in Poland that supposedly treats this? Does anyone have anything that helped this. I want to get this out of my body ASAP????"

• Dora
• Taken for 1 to 2 years
• June 23, 2022

"I got a tiny amount injected in my top lip to dissolve an unwanted amount of filler and I ended up with systemic damage throughout my whole body. My face completely collapsed and all of my tissues feels like they’re tendered and are really porous. My gums hurt, my eyes have shrunk and caved into my skull. I lost my whole identity to this enzyme and I don’t know how much time I have left to live if this damage doesn’t stop, since it feels like it is dissolving me while I am alive. The safety regulations regarding this drug as a dermal filler dissolver is not existing and I am scared it won’t be for years. All I can say is do not under any circumstances use Hyaluronidase."

• Sam
• Taken for less than 1 month
• March 12, 2023

"Hello! I just wanted to add my experience. After reading all of the reviews I was absolutely petrified of getting my horrible lip filler dissolved, I ended up doing it and I am so happy with the results, no pain at all, and my lips are back to normal. It was the best choice for me and I’m so glad I went through with it despite reading all the reviews. Don’t let the horrible experiences scare you away, there are negative side effects for everything it doesn’t mean it will happen to you."

• Evelyn
• Taken for 1 to 2 years
• June 27, 2022

"I experienced a nightmare from hyaluronidase. A year ago I had Hyaluronidase in my face to reduce fillers. After that I felt a burning sensation and terrible nerve pain. Dry eyes, nose, mouth, tachycardia, etc. It's been a year and I'm still suffering from pain, especially dryness in the mucous membranes, right now I can see dots and lines and blurry. Please don't use hyaluronidase even if the doctors say it has no side effects. I used to be healthy and never had any problems ."

• Anonymous
• Taken for less than 1 month
• May 15, 2022

"Caused a strange disease that appeared 8 months later. Strange randomized swellings on my lips and area. Starts with tingling and then swells greatly. Lasts minimum a few days, happened every week. Could be nerve related as felt tingling in chin area as well. Also area that was dissolved did not go back to "normal". It grew a new visible vein, and looked like I had aged 20 years."