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Zoladex User Reviews & Ratings (Page 3)

Zoladex has an average rating of 6.8 out of 10 from a total of 96 reviews on Drugs.com. 54% of reviewers reported a positive experience, while 19% reported a negative experience.

Reviews for Zoladex

  • louro...
  • Taken for 1 to 2 years
  • March 13, 2016

For Endometriosis "Have been on zoladex once a month injections for a year now. Awful side effects for the first 8 months . Terrible joint pain, hot flushes, bowel habit changes, bad mood swings, complete lack of sex drive, depression that drive me to contemplate my place on earth, lethargy . Also massive weight gain ....Over 2 stones. The plus is I now am free from periods and the horrific pain I endured. Prior to zoladex I had an ablation where they burnt off my womb lining. This was unsuccessful . Make your choice as the side effects are really awful but the pain I suffered was so life limiting . I would be screaming out in pain unable to move a muscle. Now I am pain free."

6 / 10
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  • Connie
  • Taken for 1 to 6 months
  • July 27, 2022

For Prostate Cancer "I had my implant 6 weeks ago. My PSA dropped significantly but the side effects were severe: night sweats even though if my air conditioning was set at 17c. My average blood pressure rose from 120/65 to 140/75 and my blood sugar also rose from 5.5 to 8.3. So Zoladex works but beware that the side effects can be quite distressing."

8 / 10
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4 Report
  • Jane
  • September 21, 2018

For Bleeding Disorder "I’m 40 and have no children, I was suffering abnormal bleeding due to fibroids but no pain. I was loosing so much blood, I had been rushed into hospital on several occasions. The bleeding caused me to suffer severe anaemia. I was really happy when zoladex was suggested as it meant I didn’t have to have a hysterectomy, unfortunately my experience was not good. I had my first injection and about 2 weeks in I was having cluster headaches, depression, my whole body ached, I was getting confused, the hot sweats were unbearable, I put nearly 2 stone on and I was an emotional wreck, I still had the second injection and was taking HRT to help but the zolidex was taking over. The gynaecologist had then told me not to have the 3rd, my last one was 7 weeks ago but I’m feeling so much better all ready. I would never have zoladex again I’m booked in for a hysterectomy now and can’t wait for it all to be over so I can get back to being myself. I would never take zoladex again"

1 / 10
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9 Report
  • colin
  • Taken for 1 to 6 months
  • March 7, 2023

For Prostate Cancer "Early-stage prostate cancer. Now on the third session of the Zoladex implant. PSA rapidly reduced. No not sweats or mood swings. Definite muscle and energy loss despite regular visits to the gym to try and keep fit. Small price to pay."

9 / 10
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3 Report
  • Everest
  • Taken for 1 to 6 months
  • July 28, 2019

For Endometriosis "I've had my 3rd monthly injection and can honestly say this drug has been life changing. I'm awaiting total hysterectomy but have thyroid issues which are delaying the anaesthetic. Have had years of heavy bleeding from undiagnosed endo, a huge fibroid in my uterus and ovarian endometriomas. Both ureters were compressed but within a couple of weeks of the first injection, I could pass urine freely again, all the bleeding stopped and my tummy felt normal again!! I've had headaches, hot flashes and brain fog but no issues with mood or skin/hair/weight etc. Very grateful to be symptom free even if it's only temporary!!"

10 / 10
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7 Report

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  • Tyiokhv
  • Taken for 1 to 6 months
  • March 8, 2022

For Endometriosis "Awful! Had three and experienced constant neck, shoulder, calf and bone pain everyday. I’m still experiencing these pains one month after stopping Zoladex. I was also given HRT add back and it didn’t help at all. Feeling anxious, tired, constant headaches and the pain all over is terrible. Hoping once my periods return I will also return to feeling normal"

1 / 10
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4 Report
  • VREmrs
  • Taken for 1 to 6 months
  • September 20, 2017

For Endometriosis "I have been on this injection for three months and it has changed my life! I wake up happy not worrying about what day of the month it is and being totally pain free From this awful disease! It has stopped the inflammation of the endometriosis which is growing all over my womb and ligaments and I'm not bleeding every 21 days! My skin in perfect my nails strong and weight has stayed the same despite an increase in appetite ! No heaving floods or crippling cramps and bowel pain! Also just started Taking the Tipolone to counteract bone issues just dreading the last zoladex injection and getting my periods back for that three month stop gap. 3 months of misery . But side affects have been hot flushes and anxiety hoping tipolone works."

10 / 10
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9 Report
  • Anonymous
  • Taken for 1 to 6 months
  • September 7, 2018

For Endometriosis "I had a laparoscopy to treat endometriosis a month before beginning course of treatment. Monthly dose. On implant 3 of 6. First month was most difficult. No period after first month. Chronic pelvic pain has subsided. Pain and bleeding on injection site, bloating, nausea, fatigue, lethargy, dizziness, aches and pains, heavy feeling in chest and pelvic cramps for a few days after injection. Hot flushes and night sweats gradually became more intense and frequent after first month. They’re bothersome. Emotionally up and down throughout treatment with bouts of depression, anxiety and panic attacks (have a history). Headaches, a possible cause of sleep deprivation in combination with the drug. Weight, appetite, skin and hair - normal. I’m conflicted with how I feel about the drug. I can say not having chronic pelvic pain and a period has been relieving."

5 / 10
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  • Kano
  • Taken for 2 to 5 years
  • July 28, 2019

For Bleeding Disorder "The Zoladex injection has been my only saviour. I am now 24, I was put on the drug to initially ‘reset’ my reproductive system to see if it could stop my excessive unexplained bleeding but once coming off zoladex last year for 6 months the same pattern emerged. I have now had over 20 Zoladex injections with the intention of continuing this until I have children. I have been lucky in the sense that I have regained my life in being able to participate in normal experiences without the worrying of bleeding everywhere. I’ve experienced some of the side effects including hot flushes, weight gain, headaches and bone pain which comes and then goes just as quickly (besides the weight sadly). Depression is definitely something I have mildly developed since being on the drug but the continuous bleeding was leading me down that path anyway!"

8 / 10
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6 Report
  • Molster
  • March 5, 2017

For Bleeding Disorder "Stopped periods as expected great news no more heavy bleeding stopped chronic pain that dropped me to my knees when standing or moving Downsides are memory loss, chronic fatigue, bone pain, loss of hair, sore breasts I'm on zoladex 3.6 once a month with HRT injection number 4 Overall I'm in less pain but still struggling with every day tasks and to carry on working as a normal healthy 36 year old woman should be able to roll on coming off this drug and having my hysterectomy"

10 / 10
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8 Report
  • Miss...
  • Taken for 1 to 6 months
  • August 6, 2022

For Endometriosis "To be honest this drug has helped me in such a way that I don't get admitted at the hospital anymore whenever I'm my period due to fibroids and endometriosis. My doctor recommended zoladex for me after my surgery for three months, I'm done with the last one and now I feel no pain and no bleeding just that the side effect is sometimes unbearable. Severe hot flashes, sweating ,acne, hair breakage, bone pain, dizziness fortunately for me I had no mood swings. In all I don't regret using the drug the only unfortunate thing is that it is expensive"

10 / 10
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  • Molly
  • Taken for less than 1 month
  • March 21, 2023

For Endometriosis "One injection of lower dose Zoladex was all it took to give me permanent headaches in the forehead region. I could hardly walk. I felt every bone in my body. Dizziness, vomiting. The blood tests showed Raised sugar levels that would become permanent, as high calcium in my blood. I am not allowed to take Zoladex now because it had severe side effects. My fibroid shank a little bit, but Zoladex didn't return any benefits other than making me very ill. I have never felt the same after taking this medication. Don't treat pain temporarily with Zoladex it causes more harm long term. My headache today has lasted three days I take panadol most days."

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  • Berley
  • Taken for 1 to 6 months
  • January 23, 2021

For Bleeding Disorder "I’m 38 and have a 13yr old but was planning on having more kids. All was normal till I hit my 30s when my heavy bleeding started then I notified my Gp. I was prescribed iron tablets and tranexamic acid to control my bleeding. A year or so later, I was diagnosed with multiple fibroids leading to severely anemic, cramping, my 5 day cycle now lasting 7 days or more, clotting. With the tranexamic acid not helping at all, I had to drop it. My partner and I have been trying to conceive for the last 6 yrs to no avail. I’ve had a couple unsuccessful fibroid resection surgeries. My Gynae has started me on Zoladex 3.6 to help shrink the fibroid in preparation for my Myomectomy. Had my 4th injection 2 days ago, the hot flashes are a pain in the butt but feels good to be free of my cycle for now. My anxiety has calm down. Hopefully I’m not on Zoladex for long as it’s not advisable with fibroids for more than 3 months??? My gynae advises longer but I'm skeptical about this. Just want this over with"

6 / 10
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  • Harriet
  • Taken for 1 to 6 months
  • December 27, 2021

For Bleeding Disorder "I’m 2.5 months into Zoladex treatment. Was extremely nervous at first but have been pleasantly surprised. Side effects only started 4th week into treatment. Hot flashes are not as bad as I thought they’d be. Headaches are probably my worst symptom - nothing a Paracetamol can’t help though. No period has been life changing. I have had a great improvement in my mental health too."

10 / 10
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  • daspi...
  • Taken for 1 to 6 months
  • May 30, 2021

For Endometriosis "Hello, Due to endometriosis and adenomyosis I had undergone surgery before 2 months of starting my Zoladex 3.6 mg for 3 months. Most important, after taking the first injection of it my bleeding continued for 15 days and i was feeling just restless during this time as it was so heavy and unmanageable. My instructor advised me not to take "Pause" to stop it as its main activity is to wash all blood and extra tissues which were not possible to remove during surgery. Now I will take my 3rd injection but since then I had no periods. Hot flashes are quite normal and manageable."

8 / 10
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  • Busym...
  • April 4, 2021

For Endometriosis "I suffer from endo and adenomyosis and when I have a flare up the pain is so severe it makes me vomit. Unbearable, hospitalised several times and have had several surgeries. Zoladex is A LIFESAVER!!! I was on it for 9 mths last year then after being off it for a few months for IVF I had a bad flare up of my adeno, had the zoladex shot and overnight the swelling and inflammation in my abdomen disappeared and my waist shrunk by 15 cm. Side effects are annoying - I have had a few angry sweaty outbursts that I know were 100% just side effects. Also there is a well known “zoladex flare” where your bleeding and pain symptoms will act up again around 7 days after injection. But after that it is much less. I didn't like the Mirena but I love Zoladex. Would be great to get the benefits without the side effects but it is not a perfect world. For me, it is totally worth it to deal with the pain and try to preserve my fertility."

10 / 10
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  • Joy
  • Taken for 6 months to 1 year
  • April 23, 2021

For Bleeding Disorder "Years of heaving bleeding. It got to the point of me collapsing in a pool of blood and being rushed into hospital a few times on blood transfusions. Fibroids were the cause . I started on Zoladex August 2020 only 1 positive is no bleeding . I can go on forever the list of negatives . Depression, looking 9 months pregnant for the last 9 months even though I'm not . Hot sweats that are so bad at night that I sleep with a fan on full and cut off my long hair to cope. I have itchy lumpy skin all over . Feeling tired, no infection exhausted, due my 10th zoladex and still waiting for a full hysterectomy. Apparently the list is long I'm on category 2 which is urgent. I can't see an end to this nightmare. I am hoping for surgery soon and get my slim body back and live life again."

7 / 10
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  • Judd
  • Taken for 1 to 6 months
  • September 9, 2018

For Endometriosis "After 10 years of endo & bowel pain, 3 laparoscopies (the last one docs said there was no endo!) and years of constant stomach pain, it has gone almost. I’m on the monthly injections but want to try the 12 week ones as the final week the endo pain returns. The hot flushes have subsided thanks to HRT and I have no other menopausal symptoms. Thank goodness for Zolodex."

9 / 10
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  • Genie
  • Taken for 1 to 2 years
  • August 3, 2020

"This medication Zoladex saved my life when many others failed I had Premenstrual dysphoric disorder. I have 6 suicidal episodes instead of 12 suicidal episodes a year on the 3 monthly injections as they cover me for 2 months."

9 / 10
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  • Kat
  • Taken for 1 to 6 months
  • December 16, 2021

For Endometriosis "I've had 2 Zodelex injections so far. I'm awaiting surgery - hysterectomy for fibroids. After having a 3 week heavy bleed on the first month, my other symptoms are pretty mild. I've had a few headaches (but this is normal for me), a few hot flushes which are barely noticeable, but I have had painful urination due to thinning of the vagina / pelvic tissues. I believe my fibroid has shrunk as can not feel the bump anymore. My breasts are not painful anymore as they would be on my normal cycle. So surprised by my lack of symptoms. Having an ultrasound after my third injection to see how much my fibroid has shrunk."

8 / 10
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  • Anonymous
  • Taken for 6 months to 1 year
  • October 19, 2021

For Endometriosis "Did not help with Endometriosis symptoms. Had terrible side effects like bone pain, joint pain, hot flashes, mood swings, hair loss. The side effects lasted for about a year after treatment with zoladex ended"

1 / 10
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  • JDano
  • April 21, 2021

For Endometriosis "I was on Zoladex for six and a half years due to Endometriosis causing severe pain and frequent hospital visits requiring morphine. Initially, for six months but I did so well on it, completely pain free that I decided to continue until menopause as opposed to a complicated hysterectomy. I tried coming off at age 49 but had to go back on due to pain coming back, I tried again at 51 and was great for 18 months but sadly intolerable pain returned although no bleeding. MRI showed large mass believed to be adenomyosis with ovaries stuck to uterus and uterus stuck to bowel very low down at the rectum! They are still reluctant to do surgery so I'm now back on zoladex aged 53. Three months in still having pain and problems. On the whole, Zoladex was great for me, I got my life back after 30 years of pain, I had some hot flushes and sleep disturbance but a small inconvenience and far more preferable than the constant pain. Although I'm having problems again, I still recommend Zoladex."

10 / 10
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  • AbbieDB
  • May 18, 2018

For Endometriosis "I had my laparoscopy beginning of November 2017 and was diagnosed with endometriosis after 7 years of issues. They fitted the mirina coil as a treatment but I was still spotting, stabbing internal pains, so when I returned to the gyno she suggested Zoladex. HATE the drug. I've only had 2 injections and have a 3rd left, which my doctors are contacting my gyno to cancel. Maybe I'm hormone sensitive or me being 22 plays a part but I'm still spotting, I've never had a cycle so that doesn't change much... Agonising joints, overall body ache, leavjng me unable to even do my office job! It's even in my spine. Worst part is I've been told they can't reverse the effects Til the drug is out my system (up to 4 months). Hot flashes happen often, but luckily I have fans to help :) I've been given the choice to be signed off for the months this lasts but I have bills. I was happier with the endo pain as it was at least manageable most days"

4 / 10
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  • Nous
  • March 3, 2018

For Endometriosis "I've just done my surgery for endometriosis and am on treatment for 6 months hope all goes well and with the zoladex injection just got muscle pain, dizziness and headache all of a sudden but it's normal as my gynecologist already told me in advanced it's side effects"

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  • Chann...
  • June 2, 2021

For Endometriosis "So I have been struggling with endometriosis since I was 16 years of age and have had the “invisible” disease that was left undiagnosed with endometriosis. I have been suffering for years and have really been on so many trials, zoladex was my last resort. I have only been on it once and there is still severe clotting, heavy bleeding, painful cramps that never go away and it’s constantly me crying in a ball. If anything I’m not going back on this again, I know I’ve only had it once but it’s not helping me at all. I’ve had no morphine to help, no laparoscopy that would help. I have been trembling and crying since last week, been feeling nauseas, angered, tearful, depressed, change of appetite and as someone who has such a short temper it makes my temper worse."

1 / 10
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1 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.